ATE387914T1 - Verfahren zur in vitro-diagnose von infektionen durch schweinecircovirus vom typ ii und diagnostische reagenzien - Google Patents

Verfahren zur in vitro-diagnose von infektionen durch schweinecircovirus vom typ ii und diagnostische reagenzien

Info

Publication number
ATE387914T1
ATE387914T1 AT03016998T AT03016998T ATE387914T1 AT E387914 T1 ATE387914 T1 AT E387914T1 AT 03016998 T AT03016998 T AT 03016998T AT 03016998 T AT03016998 T AT 03016998T AT E387914 T1 ATE387914 T1 AT E387914T1
Authority
AT
Austria
Prior art keywords
pcv
orfs
antigen
preparation
vitro
Prior art date
Application number
AT03016998T
Other languages
English (en)
Inventor
Gordon Allan
Brian Meehan
Edward Clark
John Ellis
Deborah Haines
Lori Hassard
John Harding
Catherine Elisabeth Charreyre
Gilles Emile Chappuis
Neilly Francis Mc
Original Assignee
Merial Sas
Univ Belfast
Univ Saskatchewan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27253376&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE387914(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from FR9712382A external-priority patent/FR2769321B1/fr
Priority claimed from FR9800873A external-priority patent/FR2769322B1/fr
Priority claimed from FR9803707A external-priority patent/FR2776294B1/fr
Application filed by Merial Sas, Univ Belfast, Univ Saskatchewan filed Critical Merial Sas
Application granted granted Critical
Publication of ATE387914T1 publication Critical patent/ATE387914T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C19/00—Cheese; Cheese preparations; Making thereof
    • A23C19/02—Making cheese curd
    • A23C19/032—Making cheese curd characterised by the use of specific microorganisms, or enzymes of microbial origin
    • A23C19/0321—Propionic acid bacteria
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C19/00—Cheese; Cheese preparations; Making thereof
    • A23C19/02—Making cheese curd
    • A23C19/032—Making cheese curd characterised by the use of specific microorganisms, or enzymes of microbial origin
    • A23C19/0323—Making cheese curd characterised by the use of specific microorganisms, or enzymes of microbial origin using only lactic acid bacteria, e.g. Pediococcus and Leuconostoc species; Bifidobacteria; Microbial starters in general
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16741—Use of virus, viral particle or viral elements as a vector
    • C12N2710/16743—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/24011—Poxviridae
    • C12N2710/24041—Use of virus, viral particle or viral elements as a vector
    • C12N2710/24043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/10011—Circoviridae
    • C12N2750/10021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/10011—Circoviridae
    • C12N2750/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/10011—Circoviridae
    • C12N2750/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/10011—Circoviridae
    • C12N2750/10041—Use of virus, viral particle or viral elements as a vector
    • C12N2750/10043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
    • C12N2750/00011—Details
    • C12N2750/10011—Circoviridae
    • C12N2750/10061—Methods of inactivation or attenuation
    • C12N2750/10064—Methods of inactivation or attenuation by serial passage

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Polymers & Plastics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
AT03016998T 1997-10-03 1998-10-01 Verfahren zur in vitro-diagnose von infektionen durch schweinecircovirus vom typ ii und diagnostische reagenzien ATE387914T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9712382A FR2769321B1 (fr) 1997-10-03 1997-10-03 Nouveaux circovirus porcins, vaccins et reactifs de diagnostics
FR9800873A FR2769322B1 (fr) 1997-10-03 1998-01-22 Nouveaux circovirus porcins, vaccins et reactifs de diagnostic
FR9803707A FR2776294B1 (fr) 1998-03-20 1998-03-20 Nouveaux circovirus porcins ; vaccins et reactifs de diagnostic

Publications (1)

Publication Number Publication Date
ATE387914T1 true ATE387914T1 (de) 2008-03-15

Family

ID=27253376

Family Applications (3)

Application Number Title Priority Date Filing Date
AT98946547T ATE245191T1 (de) 1997-10-03 1998-10-01 Schweinecircoviren abgeleitete impfstoffe
AT03016998T ATE387914T1 (de) 1997-10-03 1998-10-01 Verfahren zur in vitro-diagnose von infektionen durch schweinecircovirus vom typ ii und diagnostische reagenzien
AT02017134T ATE299531T1 (de) 1997-10-03 1998-10-01 Schweinecircoviren

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT98946547T ATE245191T1 (de) 1997-10-03 1998-10-01 Schweinecircoviren abgeleitete impfstoffe

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT02017134T ATE299531T1 (de) 1997-10-03 1998-10-01 Schweinecircoviren

Country Status (21)

Country Link
US (1) US6368601B1 (de)
EP (4) EP1741785B1 (de)
JP (5) JP5008218B2 (de)
KR (4) KR100736129B1 (de)
CN (2) CN100584948C (de)
AT (3) ATE245191T1 (de)
AU (1) AU756554C (de)
BR (1) BR9812845B1 (de)
CA (1) CA2305623C (de)
CY (3) CY1110359T1 (de)
DE (7) DE69816460T2 (de)
DK (4) DK1019510T3 (de)
ES (4) ES2203984T3 (de)
FR (1) FR05C0021I2 (de)
HK (1) HK1095161A1 (de)
HU (2) HU226247B1 (de)
NL (1) NL300326I2 (de)
PL (1) PL198506B1 (de)
PT (4) PT1386617E (de)
UA (1) UA78180C2 (de)
WO (1) WO1999018214A1 (de)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7192594B2 (en) * 1997-10-03 2007-03-20 Merial Limited Postweaning multisystemic wasting syndrome and porcine circovirus from pigs
WO1999029717A2 (en) * 1997-12-11 1999-06-17 University Of Saskatchewan Postweaning multisystemic wasting syndrome virus from pigs
US6517843B1 (en) * 1999-08-31 2003-02-11 Merial Reduction of porcine circovirus-2 viral load with inactivated PCV-2
US6391314B1 (en) * 1997-10-03 2002-05-21 Merial Porcine circoviruses vaccines diagnostic reagents
US20060029617A1 (en) * 1997-10-03 2006-02-09 Charreyre Catherine E Porcine circovirus and Helicobacter combination vaccines and methods of use
FR2781159B1 (fr) * 1998-07-06 2000-10-06 Merial Sas Vaccin circovirus et parvovirus porcin
US7211379B2 (en) * 1997-10-03 2007-05-01 Merial Sas Prevention of myocarditis, abortion and intrauterine infection associated with porcine circovirus-2
FR2772047B1 (fr) * 1997-12-05 2004-04-09 Ct Nat D Etudes Veterinaires E Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection
US20040062775A1 (en) * 1997-12-05 2004-04-01 Agence Francaise De Securite Sanitaire Des Aliments Circovirus sequences associated with piglet weight loss disease (PWD)
EP1816200B1 (de) * 1997-12-11 2016-03-09 Merial Virus des multisystemischen Kümmersyndroms bei Absatzferkeln
US6943152B1 (en) * 1999-06-10 2005-09-13 Merial DNA vaccine-PCV
US6497883B1 (en) 1999-06-10 2002-12-24 Merial Porcine circovirus recombinant poxvirus vaccine
ES2170622B1 (es) * 1999-12-03 2004-05-16 Consejo Superior De Investigaciones Cientificas Clones y vectores infectivos derivados de coronavirus y sus aplicaciones.
WO2001096377A2 (en) * 2000-06-15 2001-12-20 Purdue Research Foundation Vaccine for congenital tremors in pigs
US7018638B2 (en) * 2000-12-19 2006-03-28 Wyeth Mycoplasma hyopneumoniae bacterin vaccine
CN1840656B (zh) * 2001-03-27 2010-06-02 萨斯喀彻温大学 培养环状病毒的方法
CA2454397A1 (en) 2001-07-20 2003-06-05 The University Of Georgia Research Foundation, Inc. Attenuated rabies virus with nucleoprotein mutation at the phosphorylation site for vaccination against rabies and gene therapy in the cns
US7279166B2 (en) 2001-12-12 2007-10-09 Virginia Tech Intellectual Properties, Inc. Chimeric infectious DNA clones, chimeric porcine circoviruses and uses thereof
US7276353B2 (en) 2001-12-12 2007-10-02 Virginia Tech Intellectual Properties, Inc. Chimeric infectious DNA clones, chimeric porcine circoviruses and uses thereof
ATE533506T1 (de) * 2002-08-26 2011-12-15 Pfizer Prod Inc Impfstoff gegen das fortpflanzungs- und atmungssyndrom bei rindern
KR20040021988A (ko) * 2002-09-06 2004-03-11 서상희 바이러스 증식용 돼지 신장 상피 세포주, 및 이의 용도
UA95602C2 (ru) 2004-12-30 2011-08-25 Берингер Ингельхейм Ветмедика, Инк. Иммуногенная композиция цвс2 и способы приготовления такой композиции
US7700285B1 (en) 2005-12-29 2010-04-20 Boehringer Ingelheim Vetmedica, Inc. PCV2 immunogenic compositions and methods of producing such compositions
US7833707B2 (en) * 2004-12-30 2010-11-16 Boehringer Ingelheim Vetmedica, Inc. Methods of overexpression and recovery of porcine circovirus type 2 ORF2
US8834891B2 (en) * 2005-03-14 2014-09-16 Boehringer Ingelheim Vetmedica, Inc. Immunogenic compositions comprising Lawsonia intracellularis
DK1869471T3 (en) * 2005-04-13 2016-08-01 Merial Inc PROCEDURE FOR MANUFACTURING PIG CIRCOVIRUS
EP1792996A1 (de) * 2005-12-01 2007-06-06 Consejo Superior de Investigaciones Cientificas Nukleinsäuren, kodierend für Impfstoffe gegen den reproduktiven und respiratorischen Syndrom Virus (prrsv)
MX356667B (es) * 2005-12-29 2018-06-08 Boehringer Ingelheim Vetmedica Inc Uso de una composicion inmunogenica de pcv2 para reducir los sintomas clinicos en cerdos.
US20080226669A1 (en) 2005-12-29 2008-09-18 Boehringer Ingelheim Vetmedica, Inc. Multivalent pcv2 immunogenic compositions and methods of producing such compositions
KR100870077B1 (ko) * 2006-10-27 2008-11-25 권영득 이유후 전신소모성증후군(ｐｍｗｓ)의 치료용 복합제조성물
EP2101815A4 (de) 2006-12-11 2010-10-06 Boehringer Ingelheim Vetmed Wirksames verfahren zur behandlung von infektionen mit porcinem circovirus und lawsonia intracellularis
JP5200223B2 (ja) * 2006-12-15 2013-06-05 ベーリンガー インゲルハイム フェトメディカ インコーポレイテッド Ｐｃｖ２抗原によるブタの処置
EP1941903A1 (de) 2007-01-03 2008-07-09 Boehringer Ingelheim Vetmedica Gmbh Prophylaxe und Behandlung von PRDC
EP1958644A1 (de) 2007-02-13 2008-08-20 Boehringer Ingelheim Vetmedica Gmbh Vorbeugung und Behandlung von subklinischer PCVD
US8518696B2 (en) * 2007-05-11 2013-08-27 Temasek Life Sciences Laboratory Limited Production of homogeneous cell line highly permissive to porcine circovirus type 2 (PCV2) infection
KR100948127B1 (ko) * 2007-06-27 2010-03-18 주식회사 중앙백신연구소 복합호흡기 질환 돼지의 조직유제를 함유하는 백신 조성물
US20090017064A1 (en) * 2007-07-10 2009-01-15 Wyeth Methods and Compositions for Immunizing Pigs Against Porcine Circovirus
US7829274B2 (en) * 2007-09-04 2010-11-09 Boehringer Ingelheim Vetmedica, Inc. Reduction of concomitant infections in pigs by the use of PCV2 antigen
EP2225367A1 (de) * 2007-12-21 2010-09-08 Wyeth LLC Verfahren und zusammensetzungen zur immunisierung von schweinen gegen porcines circovirus
KR20100103535A (ko) * 2007-12-31 2010-09-27 베링거잉겔하임베트메디카인코퍼레이티드 외래 아미노산 삽입물을 갖는 ｐｃｖ２ ｏｒｆ２ 바이러스 유사 입자
MX2010007815A (es) * 2008-01-23 2010-08-10 Boehringer Ingelheim Vetmed Composiciones inmunogenicas de mycoplasma hyopneumoniae contra pcv2 y metodos para producir composiciones de este tipo.
AR078253A1 (es) 2009-09-02 2011-10-26 Boehringer Ingelheim Vetmed Metodos para reducir la actividad antivirica en composiciones pcv-2 y composiciones pcv-2 con mejor inmunogenicidad
TWI508974B (zh) 2010-12-22 2015-11-21 Sbc Virbac Ltd 豬第二型環狀病毒(Porcine Circovirus Type 2)、含彼之免疫組合物、檢測套組及其應用
EP2564869A1 (de) 2011-09-02 2013-03-06 Ceva Sante Animale Synthetische Kapsidproteine und deren Verwendungen
EP2789346A1 (de) 2013-04-11 2014-10-15 CEVA Santé Animale SA Fusionspolypeptide und Impfstoffe
US9649370B2 (en) 2013-05-08 2017-05-16 Protatek International, Inc. Vaccine for PCV2 and mycoplasma
MX2016003855A (es) 2013-09-25 2016-08-04 Zoetis Services Llc Composicion de vacuna de circovirus porcino tipo 2b divergente y procedimientos de uso.
MX2016004063A (es) 2013-10-02 2016-06-06 Boehringer Ingelheim Vetmed Variante de la proteina pcv2 orf2 y particulas similares al virus compuestas por esta.
CN104383527A (zh) * 2014-11-18 2015-03-04 天津瑞普生物技术股份有限公司 一种猪圆环病毒2型灭活冻干疫苗的制备方法
EP3034609A1 (de) 2014-12-19 2016-06-22 Ceva Sante Animale Rekombinanter Schweinepockenvirus und Impfstoffe
EP3294876A1 (de) 2015-05-14 2018-03-21 Merial, Inc. Verfahren zur herstellung von porcinem circovirus und von pcv2-impfstoffen
EP3254692A1 (de) 2016-06-10 2017-12-13 Ceva Sante Animale Multivalente rekombinante spv
US20200390878A1 (en) 2017-12-08 2020-12-17 Ceva Sante Animale Recombinant swinepox virus and vaccines
WO2019191005A1 (en) 2018-03-26 2019-10-03 Boehringer Ingelheim Animal Health USA Inc. Method of producing an immunogenic composition
BR112020025211A2 (pt) 2018-06-11 2021-03-09 Ceva Sante Animale Vacinação contra circovírus suíno
KR102124260B1 (ko) * 2018-10-19 2020-06-26 대한민국(관리부서 질병관리본부장) 신속 면역크로마토그래피법을 이용한 콜레라균 진단·탐지 키트 및 이를 위한 특이항체와 항체생산세포주
MX2023001024A (es) 2020-07-24 2023-02-15 Boehringer Ingelheim Animal Health Usa Inc Vacuna porcina combinada.

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4745051A (en) 1983-05-27 1988-05-17 The Texas A&M University System Method for producing a recombinant baculovirus expression vector
US4740468A (en) 1985-02-14 1988-04-26 Syntex (U.S.A.) Inc. Concentrating immunochemical test device and method
US5030558A (en) 1986-11-07 1991-07-09 Syntex (U.S.A.) Inc. Qualitative immunochromatographic method and device
US5232835A (en) 1986-11-07 1993-08-03 Syntex (U.S.A.) Inc. Qualitative immunochromatographic method and device
CA1303983C (en) 1987-03-27 1992-06-23 Robert W. Rosenstein Solid phase assay
EP0560411B1 (de) 1987-04-27 2000-07-26 Unilever N.V. Spezifische Bindungstestverfahren
US4855240A (en) 1987-05-13 1989-08-08 Becton Dickinson And Company Solid phase assay employing capillary flow
US5120643A (en) 1987-07-13 1992-06-09 Abbott Laboratories Process for immunochromatography with colloidal particles
DK175308B1 (da) * 1987-09-28 2004-08-16 Pfizer En vaccinekomposition omfattende et inaktiveret virus eller bakterium, fremgangsmåde til fremstilling deraf samt anvendelsen af en substans eller en komposition i fremstillingen deraf
DE69034168T3 (de) 1989-03-21 2013-04-11 Vical, Inc. Expression von exogenen Polynukleotidsequenzen in Wirbeltieren
FR2649013B1 (fr) 1989-07-03 1991-10-25 Seppic Sa Vaccins et vecteurs de principes actifs fluides contenant une huile metabolisable
US5141850A (en) 1990-02-07 1992-08-25 Hygeia Sciences, Inc. Porous strip form assay device method
WO1991018627A1 (en) 1990-05-29 1991-12-12 Smithkline Beecham Corporation Swine pneumonia vaccine and method for the preparation thereof
US5238652A (en) 1990-06-20 1993-08-24 Drug Screening Systems, Inc. Analytical test devices for competition assay for drugs of non-protein antigens using immunochromatographic techniques
US5565205A (en) 1990-08-16 1996-10-15 Solvay Animal Health, Inc. Inactivated Mycoplasma hypopneumoniae bacterin and method of use thereof
US5266497A (en) 1990-08-31 1993-11-30 Japan Synthetic Rubber Co., Ltd. Immunochromatographic assay with improved colored latex
US5451504A (en) 1991-07-29 1995-09-19 Serex, Inc. Method and device for detecting the presence of analyte in a sample
DE69206631T2 (de) 1991-10-14 1996-05-15 Akzo Nobel Nv Impfstoff gegen das Fortpflanzungs- und Atmungssyndrom bei Schweinen (PRRS) und Diagnose.
US5338543A (en) * 1992-02-27 1994-08-16 Ambico, Inc. Thimerosal inactivated mycoplasma hyopneumoniae vaccine
DE9204303U1 (de) 1992-03-30 1992-06-25 Marx, Guenter Wolfgang, 7953 Bad Schussenried, De
EP0571648A1 (de) 1992-05-26 1993-12-01 Chung-Nan Weng Gegen mycoplasmale Lungenentzündung schützender Impfstoff
US6592873B1 (en) * 1992-10-30 2003-07-15 Iowa State University Research Foundation, Inc. Polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus (PRRSV) and proteins encoded by the polynucleic acids
FR2700957B1 (fr) 1993-01-29 1995-03-03 Seppic Sa Composition de vaccin sous-unitaire recombinant vivant et procédé de préparation.
CN1080300C (zh) 1993-02-08 2002-03-06 美国拜尔公司 培养猪生殖和呼吸综合症病毒的方法及其在疫苗中的应用
FR2702373B1 (fr) 1993-03-08 1996-06-07 Rhone Merieux Emulsions vaccinales fluides eau-dans-l'huile contenant une huile métabolisable.
IL108915A0 (en) 1993-03-18 1994-06-24 Merck & Co Inc Polynucleotide vaccine against influenza virus
ES2074950B1 (es) 1993-09-17 1996-03-16 Iberica Cyanamid Vacuna para la prevencion de la enfermedad reproductiva y respiratoria de la cerda.
CA2181832C (en) 1994-01-27 2012-11-27 Harriet L. Robinson Immunization by inoculation of dna transcription unit
PT676467E (pt) * 1994-04-11 2002-02-28 Akzo Nobel Nv Estirpes europeias de vacina do virus do sindroma reprodutivo e respiratorio porcino (prrsv)
CA2196865C (en) * 1994-08-05 2001-07-03 Karl P. Schneider Self-chamfering drill bit
FR2781159B1 (fr) * 1998-07-06 2000-10-06 Merial Sas Vaccin circovirus et parvovirus porcin
WO1999029717A2 (en) * 1997-12-11 1999-06-17 University Of Saskatchewan Postweaning multisystemic wasting syndrome virus from pigs
FR2772047B1 (fr) * 1997-12-05 2004-04-09 Ct Nat D Etudes Veterinaires E Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection
KR100298125B1 (ko) * 1999-04-15 2001-09-13 정명식 구리의 화학 증착에 유용한 유기 구리 전구체

Also Published As

Publication number Publication date
US6368601B1 (en) 2002-04-09
BR9812845A (pt) 2000-08-08
DE122008000069I1 (de) 2009-11-05
DE69816460D1 (de) 2003-08-21
KR100854615B1 (ko) 2008-08-27
AU756554B2 (en) 2003-01-16
UA78180C2 (uk) 2007-03-15
PT1386617E (pt) 2008-06-17
DE69830858D1 (de) 2005-08-18
EP1281760A1 (de) 2003-02-05
DK1741785T3 (da) 2014-11-10
KR20060079256A (ko) 2006-07-05
PL198506B1 (pl) 2008-06-30
CY1115749T1 (el) 2017-01-25
DK1019510T3 (da) 2003-11-10
KR100904852B1 (ko) 2009-06-25
DE69839227T2 (de) 2009-03-12
HU226247B1 (en) 2008-07-28
EP1281760B9 (de) 2005-12-28
DE69816460T2 (de) 2004-05-27
JP5008218B2 (ja) 2012-08-22
CN1278301A (zh) 2000-12-27
EP1741785B1 (de) 2014-10-01
EP1019510B1 (de) 2003-07-16
KR20090051274A (ko) 2009-05-21
DE05014998T1 (de) 2008-11-20
JP4680245B2 (ja) 2011-05-11
PL339631A1 (en) 2001-01-02
ES2246001T3 (es) 2006-02-01
EP1386617A1 (de) 2004-02-04
HUP0003756A3 (en) 2003-03-28
EP1281760B1 (de) 2005-07-13
EP1741785A1 (de) 2007-01-10
DK1386617T3 (da) 2008-07-07
JP2001519159A (ja) 2001-10-23
DE69830858T2 (de) 2006-04-20
DK1281760T5 (da) 2006-04-18
HK1095161A1 (en) 2007-04-27
JP2012193179A (ja) 2012-10-11
KR20080023271A (ko) 2008-03-12
HU230340B1 (hu) 2016-02-29
CN101724606B (zh) 2016-02-24
JP2008086317A (ja) 2008-04-17
JP2011135875A (ja) 2011-07-14
ES2203984T3 (es) 2004-04-16
KR100736129B1 (ko) 2007-07-06
BR9812845B1 (pt) 2010-03-09
AU756554C (en) 2003-09-18
CY1108113T1 (el) 2014-02-12
EP1386617B1 (de) 2008-03-05
PT1281760E (pt) 2005-11-30
ES2302885T3 (es) 2008-08-01
NL300326I2 (nl) 2008-04-01
NL300326I1 (nl) 2008-03-03
JP2015109840A (ja) 2015-06-18
DE69830858T4 (de) 2006-12-21
ATE245191T1 (de) 2003-08-15
CY1110359T1 (el) 2015-04-29
CN101724606A (zh) 2010-06-09
EP1019510A1 (de) 2000-07-19
KR20010030930A (ko) 2001-04-16
HUP0003756A2 (hu) 2001-02-28
HU0800330D0 (en) 2008-07-28
CA2305623A1 (fr) 1999-04-15
CN100584948C (zh) 2010-01-27
JP5869658B2 (ja) 2016-02-24
JP5362750B2 (ja) 2013-12-11
PT1019510E (pt) 2003-11-28
AU9355598A (en) 1999-04-27
DE122005000009I1 (de) 2005-08-04
WO1999018214A1 (fr) 1999-04-15
ATE299531T1 (de) 2005-07-15
DK1281760T3 (da) 2005-10-31
KR100944144B1 (ko) 2010-02-24
CA2305623C (en) 2008-04-01
ES2524359T3 (es) 2014-12-05
PT1741785E (pt) 2014-11-13
FR05C0021I1 (de) 2005-05-27
FR05C0021I2 (de) 2005-10-21
DE69839227D1 (de) 2008-04-17

Similar Documents

Publication Publication Date Title
ATE387914T1 (de) Verfahren zur in vitro-diagnose von infektionen durch schweinecircovirus vom typ ii und diagnostische reagenzien
TWI508974B (zh) 豬第二型環狀病毒(Porcine Circovirus Type 2)、含彼之免疫組合物、檢測套組及其應用
Potgieter Immunology of bovine viral diarrhea virus
US20200237894A1 (en) Pcv2 orf2 carrier platform
Hamers et al. Diversity among bovine pestiviruses
Hahn et al. Construction of recombinant swinepox viruses and expression of the classical swine fever virus E2 protein
Jóźwik et al. Vaccination against porcine parvovirus protects against disease, but does not prevent infection and virus shedding after challenge infection with a heterologous virus strain
Lorena et al. Classical swine fever virus (C strain) distribution in organ samples of inoculated piglets
Hammond et al. A prime-boost vaccination strategy using naked DNA followed by recombinant porcine adenovirus protects pigs from classical swine fever
RU2000111496A (ru) Новые цирковирусы свиней, вакцины и реагенты для диагностики
Lefebvre et al. Increased porcine circovirus type 2 replication in porcine leukocytes in vitro and in vivo by concanavalin A stimulation
Yang et al. Biophysical characterization of Japanese encephalitis virus (KV1899) isolated from pigs in Korea
Moennig et al. Prolonged persistence of cytopathogenic bovine viral diarrhea virus (BVDV) in a persistently viremic cattle
CN108218982A (zh) 人巨细胞病毒anti-UL148多克隆抗体及其制备方法与应用
Zelník Diagnosis of Marek's disease
Kaden et al. Oral vaccination against classical swine fever with a chimeric Pestivirus: comparative investigations of liquid and lyophilized virus
TWI393778B (zh) Recombinant swine fever virus E2 glycoprotein, its single source antibody and its application in diagnostic reagents and subunit vaccines (2)
Batra et al. A severe outbreak of contagious pustular dermatitis in a sheep flock
Jarullah et al. Prevalence of Bovine viral diarrhea virus in cattle herds from Basrah and Nassirya Provinces by direct and indirect Elisa and Real time qPCR
CN104645326A (zh) 一种预防猪流行性腹泻疾病的疫苗
CN104667296A (zh) 一种预防猪流行性腹泻疾病的疫苗
Mahmoud et al. Isolation and molecular identification of BHV-1 from cattle suffering from respiratory signs
Ventura Studies on experimental molecular vaccines for bovine viral diarrhoea virus.
Abd et al. Unmasking the effect of bovine viral diarrhea virus on macrophage inflammatory functions
AWADALLA et al. BIOCHEMICAL AND MOLECULAR GENETICS DISTINCTION AMONG SHEEP POX VIRUS STRAINS

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1386617

Country of ref document: EP