ES2369547T3 - Procedimiento para el tratamiento de enfermedades humanas asociadas con un contenido elevado del ácido desoxirribonucleico en los espacios extracelulares de los tejidos y preparación médica para llevar a cabo dicho procedimiento. - Google Patents
Procedimiento para el tratamiento de enfermedades humanas asociadas con un contenido elevado del ácido desoxirribonucleico en los espacios extracelulares de los tejidos y preparación médica para llevar a cabo dicho procedimiento. Download PDFInfo
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- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/21—Endodeoxyribonucleases producing 5'-phosphomonoesters (3.1.21)
- C12Y301/21001—Deoxyribonuclease I (3.1.21.1)
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Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
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| PCT/RU2006/000642 WO2008066403A1 (fr) | 2006-11-28 | 2006-11-28 | Procédé de traitement de maladies humaines accompagnées d'une teneur plus élevée d'adn dans des espaces intercellulaires et préparation médicamenteuse destinée à sa mise en oeuvre |
Publications (2)
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| ES2369547T3 true ES2369547T3 (es) | 2011-12-01 |
| ES2369547T8 ES2369547T8 (es) | 2012-01-05 |
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| EP (1) | EP2095825B8 (enExample) |
| JP (1) | JP5372769B2 (enExample) |
| KR (1) | KR20090087095A (enExample) |
| AT (1) | ATE513557T1 (enExample) |
| ES (1) | ES2369547T3 (enExample) |
| IL (1) | IL199005A (enExample) |
| PL (1) | PL2095825T3 (enExample) |
| WO (1) | WO2008066403A1 (enExample) |
Families Citing this family (18)
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| US8388951B2 (en) * | 2003-07-14 | 2013-03-05 | Cls Therapeutics Limited | Method for treating systemic DNA mutation disease |
| US8431123B2 (en) | 2003-07-14 | 2013-04-30 | Cls Therapeutics Limited | Method for treating systemic bacterial, fungal and protozoan infection |
| US8710012B2 (en) | 2003-07-14 | 2014-04-29 | Cls Therapeutics Limited | Method for treating oncological diseases |
| US8916151B2 (en) * | 2005-04-25 | 2014-12-23 | Cls Therapeutics Limited | Method for treating a reduction of fertility |
| ATE513557T1 (de) | 2006-11-28 | 2011-07-15 | Cls Therapeutics Ltd | Verfahren zur behandlung von krankheiten des menschen im zusammenhang mit einem erhöhten desoxyribonucleinsäuregehalt in extrazellulären räumen von geweben und medizinische zubereitung zur durchführung des verfahrens |
| KR20130128478A (ko) | 2009-09-18 | 2013-11-26 | 닛뽄 가야쿠 가부시키가이샤 | 글리세린의 탈수 반응에 의한 아크롤레인 및/또는 아크릴산의 제조용 촉매 및 방법 |
| US10617743B2 (en) | 2014-06-19 | 2020-04-14 | Cls Therapeutics Limited | Method to improve safety and efficacy of anti-cancer therapy |
| RU2017125957A (ru) | 2015-01-04 | 2019-02-04 | Проталикс Лтд. | Модифицированная днказа и ее применения |
| RU2726131C2 (ru) * | 2015-05-22 | 2020-07-09 | Дмитрий Дмитриевич Генкин | Внеклеточная днк в качестве терапевтической мишени при нейродегенерации |
| EP3359658A2 (en) | 2015-10-07 | 2018-08-15 | Novozymes A/S | Polypeptides |
| WO2018197547A1 (en) | 2017-04-25 | 2018-11-01 | Lipoxen Technologies Limited | Methods of treating diseases related to net formation with parenteral administration of polysialylated dnase i |
| KR20200122320A (ko) | 2018-01-16 | 2020-10-27 | 씨엘에스 테라퓨틱스 리미티드 | 데옥시리보뉴클레아제 (dnase) 활성을 갖는 효소의 간 발현에 의한 질환의 치료 |
| US12480150B2 (en) | 2018-06-29 | 2025-11-25 | Viktor Veniaminovich Tets and Georgy Viktorovich TETS | Compositions for modulating gut microbiota |
| US20200046809A1 (en) * | 2018-08-07 | 2020-02-13 | Bradley G. Thompson | Methods for regulating endogenous production of dnase1 |
| AU2019401586A1 (en) * | 2018-12-17 | 2021-07-29 | Dennis C. Mynarcik | Compositions and methods for removing dental calculi |
| US12478571B2 (en) | 2018-12-17 | 2025-11-25 | Pontis Biologics, Inc. | Enzyme based compositions and methods for removing dental calculi |
| CA3194643A1 (en) | 2020-10-07 | 2022-04-14 | Ilya Ruderfer | Long-acting dnase |
| WO2022249170A1 (en) * | 2021-05-24 | 2022-12-01 | Peri-Ness Technologies Ltd | Therapeutic regimen with dnase |
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| ATE132742T1 (de) | 1991-08-16 | 1996-01-15 | Vical Inc | Zusammensetzung und verfahren zur behandlung von zystischer fibrose |
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| EP0879289B1 (en) | 1996-02-05 | 2006-07-05 | Genentech, Inc. | Human dnase resistant to actin inhibition |
| AU2324997A (en) * | 1996-03-15 | 1997-10-01 | Penn State Research Foundation, The | Detection of extracellular tumor-associated nucleic acid in blood plasma or ser um using nucleic acid amplification assays |
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| RU2227029C2 (ru) | 1998-07-16 | 2004-04-20 | Рисерч Дивелопмент Фаундейшн | Новые днк-расщепляющие противоопухолевые агенты |
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| JP2002530436A (ja) | 1998-11-25 | 2002-09-17 | ジェネティカ インコーポレイテッド | 増殖能を増強しかつ複製老化を防止する方法及び試薬 |
| DE60035851D1 (de) * | 1999-08-17 | 2007-09-20 | Tanuma | Deoxyribonuklease, dafür kodierendes gen und verfahren |
| US6428785B1 (en) * | 1999-10-28 | 2002-08-06 | Immunolytics Inc. | Method and composition for treating prostate cancer |
| UA78486C2 (uk) | 1999-12-10 | 2007-04-10 | Хемджен Корпорейшн | Композиція для перорального введення птахам та тваринам для лікування або зниження ризику інфекції травного тракту (варіанти), її застосування (варіанти) та спосіб лікування або зниження ризику інфекцій травного тракту (варіанти) |
| WO2001074905A1 (en) | 2000-04-03 | 2001-10-11 | Antisoma Research Limited | Compounds for targeting |
| RU2202109C1 (ru) | 2001-08-03 | 2003-04-10 | Научно-исследовательский институт неврологии РАН | Способ выявления степени нарушения реологических свойств крови |
| RU2207876C1 (ru) | 2001-11-08 | 2003-07-10 | Ткаченко Виталий Васильевич | Способ комплексно-индивидуализированного воздействия на организм при медленной вирусной инфекции и способ подготовки лабораторного животного для испытания способа такого воздействия |
| WO2003068254A1 (en) * | 2002-02-18 | 2003-08-21 | University Of Southampton | Glycosaminoglycan-dnase combination therapy |
| RU2207676C1 (ru) | 2002-04-24 | 2003-06-27 | ООО "Предприятие "Контакт-1" | Плоский радиолокационный отражатель |
| DE10221194B4 (de) | 2002-05-13 | 2005-02-10 | Fryda, Waltraud, Dr.med. | Hyaluronidasehaltiges Hautpflegemittel |
| US20040001817A1 (en) * | 2002-05-14 | 2004-01-01 | Giampapa Vincent C. | Anti-aging nutritional supplement |
| RU2239442C1 (ru) | 2003-05-05 | 2004-11-10 | Красноярская государственная медицинская академия | Способ профилактики внутриутробных инфекций у детей |
| RU2269358C2 (ru) * | 2003-07-14 | 2006-02-10 | Дмитрий Дмитриевич Генкин | Способ лечения генерализованных инфекций, вызываемых бактериями, или заболеваний, вызываемых грибами и простейшими, или атеросклероза, или сахарного диабета, или заболеваний, связанных с реакцией гиперчувствительности замедленного типа, или заболеваний, обусловленных мутациями генов соматических клеток |
| US8710012B2 (en) * | 2003-07-14 | 2014-04-29 | Cls Therapeutics Limited | Method for treating oncological diseases |
| US8431123B2 (en) * | 2003-07-14 | 2013-04-30 | Cls Therapeutics Limited | Method for treating systemic bacterial, fungal and protozoan infection |
| RU2269359C2 (ru) | 2004-03-12 | 2006-02-10 | Дмитрий Дмитриевич Генкин | Способ профилактики развития онкологических заболеваний или инфекций, вызываемых бактериями, грибами и простейшими, или атеросклероза, или сахарного диабета, или заболеваний, связанных с реакцией гиперчувствительности замедленного типа, или заболеваний, развивающихся вследствие мутации генов соматических клеток (варианты) |
| US8388951B2 (en) * | 2003-07-14 | 2013-03-05 | Cls Therapeutics Limited | Method for treating systemic DNA mutation disease |
| RU2269356C2 (ru) * | 2003-07-14 | 2006-02-10 | Дмитрий Дмитриевич Генкин | Способ лечения онкологических заболеваний |
| WO2005004904A1 (en) | 2003-07-14 | 2005-01-20 | Dmitry Dmitrievich Genkin | Method for treating diseases associated with modifications of qualitative and/ quantitative composition of blood extracellular dna (variants) |
| EP1666055A4 (en) | 2003-07-14 | 2010-02-10 | Viktor Veniaminovich Tets | METHOD OF TREATMENT OF ONCOLOGICAL, INFECTIOUS, AND SOMATIC DISEASES, METHODS OF MONITORING THE EFFICACY OF TREATMENT, AGENTS AND PHARMACEUTICAL COMPOSITIONS THEREOF |
| RU2239404C1 (ru) | 2003-09-17 | 2004-11-10 | Бессонов Дмитрий Михайлович | Способ профилактики старения организма человека |
| RU2269357C2 (ru) | 2004-03-12 | 2006-02-10 | Дмитрий Дмитриевич Генкин | Способ замедления наступления болезненных состояний, связанных с увеличением возраста человека |
| RU2267329C2 (ru) | 2004-03-12 | 2006-01-10 | Дмитрий Дмитриевич Генкин | Способ лечения заболеваний, сопровождающихся изменениями качественного и/или количественного состава внеклеточной днк крови (варианты) |
| US9592277B2 (en) * | 2004-04-14 | 2017-03-14 | Avirid, Inc. | Compositions with modified nucleases targeted to viral nucleic acids and methods of use for prevention and treatment of viral diseases |
| JP3989936B2 (ja) * | 2005-04-07 | 2007-10-10 | 進 須永 | 抗腫瘍剤及び新規ｄｎアーゼ |
| US8916151B2 (en) * | 2005-04-25 | 2014-12-23 | Cls Therapeutics Limited | Method for treating a reduction of fertility |
| EP1904638A2 (en) * | 2005-07-18 | 2008-04-02 | Metabogal Ltd. | Mucosal or enteral administration of biologically active macromolecules |
| RU2308968C2 (ru) | 2005-07-19 | 2007-10-27 | Дмитрий Дмитриевич Генкин | Способ лечения заболеваний человека, сопровождающихся повышенным содержанием дезоксирибонуклеиновой кислоты во внеклеточных пространствах тканей, и лекарственный препарат для его реализации |
| CA2666794C (en) * | 2006-10-18 | 2017-12-12 | Periness Ltd. | Method and pharmacological composition for the diagnosis and treatment of male sub-fertility |
| ATE513557T1 (de) | 2006-11-28 | 2011-07-15 | Cls Therapeutics Ltd | Verfahren zur behandlung von krankheiten des menschen im zusammenhang mit einem erhöhten desoxyribonucleinsäuregehalt in extrazellulären räumen von geweben und medizinische zubereitung zur durchführung des verfahrens |
| GB0922006D0 (en) | 2009-12-17 | 2010-02-03 | Genome Res Ltd | Diagnostic |
| WO2012075506A2 (en) | 2010-12-03 | 2012-06-07 | Beth Israel Deaconess Medical Center, Inc. | Methods for predicting and treating infection-induced illnesses and predicting the severity of infection-induced illnesses |
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Also Published As
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| WO2008066403A1 (fr) | 2008-06-05 |
| IL199005A (en) | 2012-04-30 |
| ES2369547T8 (es) | 2012-01-05 |
| ATE513557T1 (de) | 2011-07-15 |
| IL199005A0 (en) | 2010-02-17 |
| US20100061971A1 (en) | 2010-03-11 |
| EP2095825A4 (en) | 2009-12-30 |
| US8871200B2 (en) | 2014-10-28 |
| KR20090087095A (ko) | 2009-08-14 |
| PL2095825T3 (pl) | 2011-12-30 |
| JP2010511039A (ja) | 2010-04-08 |
| JP5372769B2 (ja) | 2013-12-18 |
| EP2095825B1 (en) | 2011-06-22 |
| EP2095825A1 (en) | 2009-09-02 |
| EP2095825B8 (en) | 2012-03-28 |
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