ES2340807T3 - Oligonucleotidos sinteticos utiles terapeuticamente. - Google Patents
Oligonucleotidos sinteticos utiles terapeuticamente. Download PDFInfo
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- ES2340807T3 ES2340807T3 ES07015976T ES07015976T ES2340807T3 ES 2340807 T3 ES2340807 T3 ES 2340807T3 ES 07015976 T ES07015976 T ES 07015976T ES 07015976 T ES07015976 T ES 07015976T ES 2340807 T3 ES2340807 T3 ES 2340807T3
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/18—Type of nucleic acid acting by a non-sequence specific mechanism
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| US20030032610A1 (en) | 1996-06-03 | 2003-02-13 | Gilchrest Barbara A. | Method to inhibit cell growth using oligonucleotides |
| WO2000061597A1 (en) | 1999-04-08 | 2000-10-19 | Uab Research Foundation | Antiproliferative activity of g-righ oligonucleotides and method of using same to bind to nucleolin |
| US7960540B2 (en) | 1999-04-08 | 2011-06-14 | Advanced Cancer Therapeutics, Llc | Antiproliferative activity of G-rich oligonucleotides and method of using same to bind to nucleolin |
| US8114850B2 (en) | 1999-04-08 | 2012-02-14 | Advanced Cancer Therapeutics, Llc | Antiproliferative activity of G-rich oligonucleotides and method of using same to bind to nucleolin |
| US6949520B1 (en) * | 1999-09-27 | 2005-09-27 | Coley Pharmaceutical Group, Inc. | Methods related to immunostimulatory nucleic acid-induced interferon |
| JP4772245B2 (ja) * | 1999-12-13 | 2011-09-14 | バイオニケ ライフ サイエンシーズ インコーポレイテッド | 治療上有用な合成オリゴヌクレオチド |
| CA2420103A1 (en) | 2000-08-29 | 2002-03-07 | Bioniche Life Sciences Inc. | Modulation of fas and fasl expression |
| EP1350262B8 (en) * | 2000-12-08 | 2008-08-13 | Coley Pharmaceuticals GmbH | Cpg-like nucleic acids and methods of use thereof |
| US7087586B2 (en) * | 2001-04-24 | 2006-08-08 | Bioniche Life Sciences, Inc. | Oligonucleotide compositions and their use to induce differentiation of cells |
| MXPA04001315A (es) * | 2001-08-17 | 2004-05-20 | Bioniche Life Sciences Inc | Relacion de conformacion-actividad de oligonucleotidos de fosfodiester inductores de apoptosis. |
| AU2002341264B2 (en) * | 2001-10-03 | 2007-07-12 | Bioniche Life Sciences Inc. | Therapeutically useful triethyleneglycol cholesteryl oligonucleotides |
| MXPA04010415A (es) * | 2002-04-22 | 2005-02-17 | Bioniche Life Sciences Inc | Composiciones oligonucleotdias y su uso para la modulacion de respuestas inmunes. |
| AU2004226605A1 (en) * | 2003-04-02 | 2004-10-14 | Coley Pharmaceutical Group, Ltd. | Immunostimulatory nucleic acid oil-in-water formulations for topical application |
| CA2526212C (en) * | 2003-05-16 | 2013-08-27 | Hybridon, Inc. | Synergistic treatment of cancer using immunomers in conjunction with chemotherapeutic agents |
| US20080009455A9 (en) * | 2005-02-24 | 2008-01-10 | Coley Pharmaceutical Group, Inc. | Immunostimulatory oligonucleotides |
| JP2008532520A (ja) * | 2005-03-09 | 2008-08-21 | ベイラー カレッジ オブ メディスン | Ｔｏｌｌ様受容体８のシグナル伝達によるｃｄ４＋調節性ｔ細胞の抑制機能の直接的な反転 |
| GB2443591B (en) * | 2005-09-07 | 2010-04-28 | Secr Defence | Adjuvanted vaccine |
| CN102439149B (zh) * | 2009-02-12 | 2018-01-02 | 库尔纳公司 | 通过抑制针对胶质细胞衍生神经营养因子(gdnf)的天然反义转录物来治疗gdnf相关的疾病 |
| GB0906234D0 (en) | 2009-04-14 | 2009-05-20 | Secr Defence | Vaccine |
| KR100998365B1 (ko) | 2009-06-29 | 2010-12-06 | 압타바이오 주식회사 | 치료 효능이 있는 변형핵산 및 구아노신을 함유하는 올리고뉴클레오티드 변형체 |
| EP2490767A4 (en) * | 2009-07-15 | 2013-02-13 | Santaris Pharma As | GLI2 TARGETING TARGET ANTAGONIST FOR THE TREATMENT OF LEUKEMIA |
| JP6155533B2 (ja) * | 2012-02-28 | 2017-07-05 | 国立大学法人東京農工大学 | Ｔｄｐ−４３細胞内存在量関連疾患の認定方法 |
| EP4000597A1 (en) * | 2020-11-17 | 2022-05-25 | The Boots Company plc | Tetrapeptide and compositions comprising tetrapeptides |
| AU2022421244A1 (en) * | 2021-12-22 | 2024-07-11 | Camp4 Therapeutics Corporation | Modulation of gene transcription using antisense oligonucleotides targeting regulatory rnas |
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| US3172815A (en) * | 1962-04-24 | 1965-03-09 | Warner Lambert Pharmaceutical | Method for preparing reticulo-endo-thelial system stimulant and stimulant thereof |
| FR2160326B1 (enExample) * | 1971-11-19 | 1975-02-07 | Anvar | |
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| CA1020460A (en) * | 1973-02-23 | 1977-11-08 | Wellcome Foundation Limited (The) | Isolation of immunostimulating glycopeptide from bacteria |
| US3976544A (en) * | 1973-06-19 | 1976-08-24 | The Agence Nationale De Valorisation De Le Recherche | Water-soluble immunological adjuvants, in particular for vaccines, obtained from mycobacteria and related microorganisms and process for their extraction |
| FR2374042A1 (fr) * | 1976-06-04 | 1978-07-13 | Merieux Inst | Nouveau medicament immunostimulant et son procede de preparation |
| JPS54140710A (en) * | 1978-03-10 | 1979-11-01 | Mitsui Toatsu Chem Inc | Anti-tumor substance and its preparation |
| DE3011461C2 (de) * | 1980-03-25 | 1986-10-30 | Dr. Madaus & Co, 5000 Köln | Verwendung von Propionibakterien |
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| IT1277025B1 (it) * | 1995-12-04 | 1997-11-04 | Cooperativa Centro Ricerche Po | Classe di oligonucleotidi fosfodiesterici ad attivita' citotossica composizioni farmaceutiche che li contengono e loro uso |
| US6015710A (en) * | 1996-04-09 | 2000-01-18 | The University Of Texas System | Modulation of mammalian telomerase by peptide nucleic acids |
| CA2255822A1 (en) * | 1996-05-20 | 1997-11-27 | The Government Of The United States Of America, Represented By The Secre Tary, Department Of Health And Human Services | Oligonucleotides which specifically bind retroviral nucleocapsid proteins |
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| JP4772245B2 (ja) * | 1999-12-13 | 2011-09-14 | バイオニケ ライフ サイエンシーズ インコーポレイテッド | 治療上有用な合成オリゴヌクレオチド |
| US20020091095A1 (en) * | 1999-12-13 | 2002-07-11 | Phillips Nigel C. | Modulation of Fas and FasL expression |
| CA2395493C (en) * | 1999-12-28 | 2010-06-22 | Bioniche Life Sciences Inc. | Hyaluronic acid in the treatment of cancer |
| AU2002341264B2 (en) * | 2001-10-03 | 2007-07-12 | Bioniche Life Sciences Inc. | Therapeutically useful triethyleneglycol cholesteryl oligonucleotides |
| MXPA04010415A (es) * | 2002-04-22 | 2005-02-17 | Bioniche Life Sciences Inc | Composiciones oligonucleotdias y su uso para la modulacion de respuestas inmunes. |
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