ES2287687T3 - Purificacion de polipeptidos. - Google Patents

Purificacion de polipeptidos. Download PDF

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Publication number
ES2287687T3
ES2287687T3 ES04700878T ES04700878T ES2287687T3 ES 2287687 T3 ES2287687 T3 ES 2287687T3 ES 04700878 T ES04700878 T ES 04700878T ES 04700878 T ES04700878 T ES 04700878T ES 2287687 T3 ES2287687 T3 ES 2287687T3
Authority
ES
Spain
Prior art keywords
antibody
polypeptide
lactate
homogenate
broth
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES04700878T
Other languages
English (en)
Spanish (es)
Inventor
Philip M. Lester
Josefine Persson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of ES2287687T3 publication Critical patent/ES2287687T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ES04700878T 2003-01-09 2004-01-08 Purificacion de polipeptidos. Expired - Lifetime ES2287687T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US43941803P 2003-01-09 2003-01-09
US439418P 2003-01-09

Publications (1)

Publication Number Publication Date
ES2287687T3 true ES2287687T3 (es) 2007-12-16

Family

ID=33299572

Family Applications (1)

Application Number Title Priority Date Filing Date
ES04700878T Expired - Lifetime ES2287687T3 (es) 2003-01-09 2004-01-08 Purificacion de polipeptidos.

Country Status (18)

Country Link
US (2) US7169908B2 (https=)
EP (1) EP1581644B1 (https=)
JP (1) JP2006517415A (https=)
KR (1) KR20050095605A (https=)
CN (1) CN100467611C (https=)
AT (1) ATE364092T1 (https=)
AU (1) AU2004230670B2 (https=)
BR (1) BRPI0406470A (https=)
CA (1) CA2511946A1 (https=)
DE (1) DE602004006831T2 (https=)
DK (1) DK1581644T3 (https=)
ES (1) ES2287687T3 (https=)
MX (1) MXPA05007378A (https=)
NZ (1) NZ540895A (https=)
PL (1) PL377653A1 (https=)
RU (1) RU2337968C2 (https=)
WO (1) WO2004092393A1 (https=)
ZA (1) ZA200504990B (https=)

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KR20190140090A (ko) 2007-07-09 2019-12-18 제넨테크, 인크. 폴리펩티드의 재조합 생산 동안의 디술피드 결합 환원의 방지
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CA2788607C (en) * 2010-02-01 2018-03-20 Digna Biotech,S.L. Process for the production of interferon alpha 5
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US9884904B2 (en) * 2010-03-10 2018-02-06 Hoffmann-La Roche Inc. Method for purifying polypeptide solutions
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CN107312062B (zh) 2010-05-17 2021-03-16 Emd密理博公司 用于纯化生物分子的刺激响应性聚合物
GB201012599D0 (en) 2010-07-27 2010-09-08 Ucb Pharma Sa Process for purifying proteins
DE102011001743A1 (de) * 2011-04-01 2012-10-04 Technische Universität Dortmund Verfahren zur Trennung/Reinigung von Biomolekühlen
CN107266577B (zh) * 2011-10-11 2022-09-13 弗·哈夫曼-拉罗切有限公司 双特异性抗体的改进的组装
CN102443055B (zh) * 2011-10-26 2017-07-28 浙江海正药业股份有限公司 一种重组人肿瘤坏死因子相关凋亡诱导配体的纯化工艺
SG11201407801VA (en) * 2012-05-31 2014-12-30 Agency Science Tech & Res Methods for use of mixed multifunctional surfaces for reducing aggregate content in protein preparations
CN102701501A (zh) * 2012-06-26 2012-10-03 天津市津华盛生物科技有限公司 工业乳酸链球菌素废水综合利用的方法
KR20150118103A (ko) * 2013-02-06 2015-10-21 에이전시 포 사이언스, 테크놀로지 앤드 리서치 단백질 정제 방법
SG11201505203XA (en) * 2013-02-26 2015-08-28 Agency Science Tech & Res Protein purification in the presence of nonionic organic polymers and electropositive surfaces
JP2016509068A (ja) * 2013-02-28 2016-03-24 エイジェンシー・フォー・サイエンス，テクノロジー・アンド・リサーチ クロマチン欠損細胞培養採取物からの抗体のクロマトグラフィー精製
CN105008384A (zh) 2013-02-28 2015-10-28 新加坡科技研究局 在高电导率下在非离子性有机聚合物的存在下的蛋白质纯化
RU2646098C2 (ru) * 2013-04-30 2018-03-01 Интас Фармасьютикалс Лтд Новый способ клонирования, экспрессии и очистки для получения ранибизумаба
WO2015166037A1 (en) * 2014-04-30 2015-11-05 Novozymes A/S Method for reducing the dna content of a fermentation broth
CN110234340A (zh) 2016-11-11 2019-09-13 好利恩风湿病制药有限责任公司 泼尼松和尿酸酶分子的组合疗法及其用途
US20200237881A1 (en) 2019-01-30 2020-07-30 Horizon Pharma Rheumatology Llc Reducing immunogenicity to pegloticase
CN108333263A (zh) * 2017-01-20 2018-07-27 北京蛋白质组研究中心 一种尿蛋白制备方法及尿蛋白质组的检测方法
TW201927335A (zh) * 2017-10-02 2019-07-16 美商拜耳保健有限責任公司 防止雙硫鍵於細胞培養收集物中還原之方法
BR112020010615A2 (pt) * 2017-12-22 2020-10-27 Regeneron Pharmaceuticals, Inc. produto farmacêutico proteico, método e sistema para caracterizar impurezas de produto farmacêutico proteico e de fármaco de baixo peso molecular, método para produzir um anticorpo, anticorpo, e, usos do método e do sistema
CN111363024A (zh) * 2018-12-26 2020-07-03 深圳翰宇药业股份有限公司 多肽的纯化方法
WO2020247983A1 (en) * 2019-06-05 2020-12-10 Viome, Inc. Sample collection methods and devices
EP4632063A3 (en) 2020-04-15 2025-10-22 Genentech, Inc. Copper loss mitigation
CN112708566A (zh) * 2021-01-25 2021-04-27 西南林业大学 一种黑曲霉生产胞外多聚物的优化培养基及培养方法
CN114774500A (zh) * 2022-04-26 2022-07-22 成都蜀星饲料有限公司 多肽及制备方法、有机复合微量元素及制备方法
US12269875B2 (en) 2023-08-03 2025-04-08 Jeff R. Peterson Gout flare prevention methods using IL-1BETA blockers

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Also Published As

Publication number Publication date
ZA200504990B (en) 2006-08-30
BRPI0406470A (pt) 2005-12-06
JP2006517415A (ja) 2006-07-27
DK1581644T3 (da) 2007-10-08
EP1581644B1 (en) 2007-06-06
US7169908B2 (en) 2007-01-30
EP1581644A1 (en) 2005-10-05
AU2004230670B2 (en) 2010-11-25
CA2511946A1 (en) 2004-10-28
ATE364092T1 (de) 2007-06-15
DE602004006831D1 (de) 2007-07-19
WO2004092393A1 (en) 2004-10-28
US7579448B2 (en) 2009-08-25
MXPA05007378A (es) 2005-11-23
US20070077625A1 (en) 2007-04-05
AU2004230670A1 (en) 2004-10-28
KR20050095605A (ko) 2005-09-29
US20050037456A1 (en) 2005-02-17
RU2005125210A (ru) 2006-01-10
PL377653A1 (pl) 2006-02-06
CN100467611C (zh) 2009-03-11
CN1759186A (zh) 2006-04-12
DE602004006831T2 (de) 2008-02-14
NZ540895A (en) 2007-03-30
RU2337968C2 (ru) 2008-11-10

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