PL377653A1 - Oczyszczanie polipeptydów - Google Patents

Oczyszczanie polipeptydów

Info

Publication number
PL377653A1
PL377653A1 PL377653A PL37765304A PL377653A1 PL 377653 A1 PL377653 A1 PL 377653A1 PL 377653 A PL377653 A PL 377653A PL 37765304 A PL37765304 A PL 37765304A PL 377653 A1 PL377653 A1 PL 377653A1
Authority
PL
Poland
Prior art keywords
homogenate
broth
polypeptide
lactate
polypeptides
Prior art date
Application number
PL377653A
Other languages
English (en)
Inventor
Philip M. Lester
Josefine Persson
Original Assignee
Genentech, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech, Inc. filed Critical Genentech, Inc.
Publication of PL377653A1 publication Critical patent/PL377653A1/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PL377653A 2003-01-09 2004-01-08 Oczyszczanie polipeptydów PL377653A1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US43941803P 2003-01-09 2003-01-09

Publications (1)

Publication Number Publication Date
PL377653A1 true PL377653A1 (pl) 2006-02-06

Family

ID=33299572

Family Applications (1)

Application Number Title Priority Date Filing Date
PL377653A PL377653A1 (pl) 2003-01-09 2004-01-08 Oczyszczanie polipeptydów

Country Status (18)

Country Link
US (2) US7169908B2 (pl)
EP (1) EP1581644B1 (pl)
JP (1) JP2006517415A (pl)
KR (1) KR20050095605A (pl)
CN (1) CN100467611C (pl)
AT (1) ATE364092T1 (pl)
AU (1) AU2004230670B2 (pl)
BR (1) BRPI0406470A (pl)
CA (1) CA2511946A1 (pl)
DE (1) DE602004006831T2 (pl)
DK (1) DK1581644T3 (pl)
ES (1) ES2287687T3 (pl)
MX (1) MXPA05007378A (pl)
NZ (1) NZ540895A (pl)
PL (1) PL377653A1 (pl)
RU (1) RU2337968C2 (pl)
WO (1) WO2004092393A1 (pl)
ZA (1) ZA200504990B (pl)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2316475T (pt) 1998-08-06 2017-12-21 Univ Duke Uricase tetramérica isolada
EP1539798B1 (en) * 2002-09-06 2010-11-24 Genentech, Inc. Process for protein extraction
TWI418564B (zh) * 2005-04-11 2013-12-11 Savient Pharmaceuticals Inc 利用陽離子界面活性劑之蛋白質純化
EP1871874B1 (en) 2005-04-11 2015-04-08 Crealta Pharmaceuticals LLC Variant forms of urate oxidase and use thereof
US20080032343A1 (en) 2005-12-22 2008-02-07 Genentech, Inc. Recombinant Production of Heparin Binding Proteins
PL2013225T3 (pl) * 2006-04-12 2015-06-30 Crealta Pharmaceuticals Llc Oczyszczanie białek z zastosowaniem kationowego środka powierzchniowo czynnego
FR2902799B1 (fr) 2006-06-27 2012-10-26 Millipore Corp Procede et unite de preparation d'un echantillon pour l'analyse microbiologique d'un liquide
KR101520105B1 (ko) 2006-07-14 2015-05-21 제넨테크, 인크. 재조합 단백질의 리폴딩
US8569464B2 (en) * 2006-12-21 2013-10-29 Emd Millipore Corporation Purification of proteins
WO2008079302A2 (en) * 2006-12-21 2008-07-03 Millipore Corporation Purification of proteins
US8268586B2 (en) * 2006-12-21 2012-09-18 Novozymes, Inc. Modified messenger RNA stabilizing sequences for expressing genes in bacterial cells
US8362217B2 (en) 2006-12-21 2013-01-29 Emd Millipore Corporation Purification of proteins
BRPI0806367A2 (pt) * 2007-01-22 2011-09-06 Genentech Inc métodos de purificação de anticorpos
HUE046992T2 (hu) 2007-07-09 2020-04-28 Genentech Inc Diszulfidkötés redukciójának megelõzése polipeptidek rekombináns elõállítása során
US7887821B2 (en) * 2007-12-20 2011-02-15 Alk-Abello A/S Process for producing an allergen extract
US8999702B2 (en) 2008-06-11 2015-04-07 Emd Millipore Corporation Stirred tank bioreactor
GB0818228D0 (en) * 2008-10-06 2008-11-12 Avecia Biolog Ltd Purification process
AU2009305344A1 (en) * 2008-10-17 2010-04-22 Percivia Llc. Clarification process
SG171446A1 (en) 2008-12-16 2011-07-28 Millipore Corp Stirred tank reactor and method
RU2535038C2 (ru) 2009-06-25 2014-12-10 Криэлта Фармасьютикалз ЭлЭлСи Способы и наборы для прогнозирования риска инфузионных реакций и опосредованной антителами потери ответа при терапии пэгилированной уриказой с помощью мониторинга содержания мочевой кислоты в сыворотке крови
BR112012018956B1 (pt) * 2010-02-01 2022-05-31 Digna Biotech, S.L. Processo para produção de uma proteína interferon alfa 5
WO2011098569A1 (en) * 2010-02-12 2011-08-18 Laboratorios Leti, S.L. Unipersonal Process for producing an allergen extract
JP5814951B2 (ja) * 2010-03-10 2015-11-17 エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft 免疫グロブリン溶液を精製するための方法
JO3131B1 (ar) 2010-04-27 2017-09-20 Glaxosmithkline Llc مركبات كيميائية
CN107312062B (zh) 2010-05-17 2021-03-16 Emd密理博公司 用于纯化生物分子的刺激响应性聚合物
GB201012599D0 (en) 2010-07-27 2010-09-08 Ucb Pharma Sa Process for purifying proteins
DE102011001743A1 (de) * 2011-04-01 2012-10-04 Technische Universität Dortmund Verfahren zur Trennung/Reinigung von Biomolekühlen
WO2013055958A1 (en) * 2011-10-11 2013-04-18 Genentech, Inc. Improved assembly of bispecific antibodies
CN102443055B (zh) * 2011-10-26 2017-07-28 浙江海正药业股份有限公司 一种重组人肿瘤坏死因子相关凋亡诱导配体的纯化工艺
SG11201407801VA (en) 2012-05-31 2014-12-30 Agency Science Tech & Res Methods for use of mixed multifunctional surfaces for reducing aggregate content in protein preparations
CN102701501A (zh) * 2012-06-26 2012-10-03 天津市津华盛生物科技有限公司 工业乳酸链球菌素废水综合利用的方法
JP6329179B2 (ja) * 2013-02-06 2018-05-23 エイジェンシー・フォー・サイエンス,テクノロジー・アンド・リサーチ タンパク質精製方法
SG10201610955SA (en) * 2013-02-26 2017-02-27 Agency Science Tech & Res Protein purification in the presence of nonionic organic polymers and electropositive surfaces
EP2961761B1 (en) 2013-02-28 2018-09-12 Agency For Science, Technology And Research Protein purification in the presence of nonionic organic polymers at elevated conductivity
SG11201505192RA (en) * 2013-02-28 2015-08-28 Agency Science Tech & Res Chromatographic purification of antibodies from chromatin-deficient cell culture harvests
MX368142B (es) * 2013-04-30 2019-09-20 Intas Pharmaceuticals Ltd Metodo de clonacion, expresion y purificacion novedoso para la preparacion de ranibizumab.
CN106255698B (zh) * 2014-04-30 2021-08-03 诺维信公司 用于减少发酵液的dna含量的方法
CN110234340A (zh) 2016-11-11 2019-09-13 好利恩风湿病制药有限责任公司 泼尼松和尿酸酶分子的组合疗法及其用途
CN108333263A (zh) * 2017-01-20 2018-07-27 北京蛋白质组研究中心 一种尿蛋白制备方法及尿蛋白质组的检测方法
TW201927335A (zh) * 2017-10-02 2019-07-16 美商拜耳保健有限責任公司 防止雙硫鍵於細胞培養收集物中還原之方法
SG11202004380QA (en) * 2017-12-22 2020-06-29 Regeneron Pharma System and method for characterizing drug product impurities
CN111363024A (zh) * 2018-12-26 2020-07-03 深圳翰宇药业股份有限公司 多肽的纯化方法
WO2020160325A1 (en) 2019-01-30 2020-08-06 Horizon Pharma Rheumatology Llc Reducing immunogenicity to pegloticase
EP3980349A4 (en) * 2019-06-05 2023-07-12 Viome Life Sciences, Inc. SAMPLE COLLECTION METHODS AND DEVICES
US20210371809A1 (en) 2020-04-15 2021-12-02 Genentech, Inc. Copper loss mitigation
CN112708566A (zh) * 2021-01-25 2021-04-27 西南林业大学 一种黑曲霉生产胞外多聚物的优化培养基及培养方法
CN114774500A (zh) * 2022-04-26 2022-07-22 成都蜀星饲料有限公司 多肽及制备方法、有机复合微量元素及制备方法
US12269875B2 (en) 2023-08-03 2025-04-08 Jeff R. Peterson Gout flare prevention methods using IL-1BETA blockers

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL34079A (en) * 1969-04-01 1973-02-28 Upjohn Co Purification of ypsilon-globulins
US3607857A (en) * 1970-03-03 1971-09-21 Upjohn Co Process of removing acrinol from gamma globulin using siliceous material such as silica gel
US3903254A (en) * 1971-07-23 1975-09-02 Upjohn Co Separation of erythrocyte stroma from lysing medium and hemoglobin with acrinol
DE2308013A1 (de) 1973-02-17 1974-09-12 Behringwerke Ag Katalasearme glucoseoxidase und verfahren zu ihrer gewinnung
JPS519035B2 (pl) 1973-10-31 1976-03-23
SU944580A1 (ru) 1980-02-07 1982-07-23 Кировский научно-исследовательский институт переливания крови Способ получени поверхностного антигена гепатита В
CA1237998A (en) * 1984-04-14 1988-06-14 Akihiro Ginnaga Method for purification of filamentous hemagglutinin
JPS60258127A (ja) 1984-06-04 1985-12-20 Green Cross Corp:The B型肝炎ワクチンの製造方法
WO1986007093A1 (fr) 1985-05-29 1986-12-04 The Green Cross Corporation Procede de preparation d'une proteine heterogene
EP0227833B1 (en) 1985-07-16 1991-01-16 Green Cross Corporation Process for preparing hetero-protein
DE3604947A1 (de) 1986-02-17 1987-08-20 Biotest Pharma Gmbh Verfahren zur herstellung eines immunglobulinhaltigen praeparates und dessen verwendung zur prophylaxe und therapie von aids
FR2600078B1 (fr) 1986-06-12 1989-07-13 Merieux Inst Procede de preparation de facteur xiii a partir du placenta
DE3929504A1 (de) 1989-09-06 1991-03-07 Behringwerke Ag Verfahren zur reinigung von plasminogen-aktivator-inhibitor 2 (pai-2)
DE4030264A1 (de) * 1990-09-25 1992-04-23 Hoechst Ag Verfahren zur herstellung gereinigter glycolipide durch membrantrennverfahren
GB9215540D0 (en) 1992-07-22 1992-09-02 Celltech Ltd Protein expression system
US5861263A (en) * 1992-10-20 1999-01-19 Universidad Autonoma De Nuevo Leon Preparation of preserved entamoeba histolytica antigens without enzymatic inhibitors and their use in immunological methods
US5641870A (en) 1995-04-20 1997-06-24 Genentech, Inc. Low pH hydrophobic interaction chromatography for antibody purification
US5760189A (en) 1995-06-02 1998-06-02 Genetics Institute, Inc. Protein recovery & purification methods
US5714583A (en) 1995-06-07 1998-02-03 Genetics Institute, Inc. Factor IX purification methods
EP0998486B2 (en) 1997-06-13 2012-02-01 Genentech, Inc. Protein recovery by chromatography followed by filtration upon a charged layer
JPH11341947A (ja) * 1998-06-02 1999-12-14 Yakult Honsha Co Ltd 発酵管理方法
US6156514A (en) * 1998-12-03 2000-12-05 Sunol Molecular Corporation Methods for making recombinant cells
ES2252187T3 (es) * 2000-01-20 2006-05-16 Regents Of The University Of Minnesota Peptidos con actividad antibacteriana.

Also Published As

Publication number Publication date
DE602004006831D1 (de) 2007-07-19
DK1581644T3 (da) 2007-10-08
MXPA05007378A (es) 2005-11-23
ATE364092T1 (de) 2007-06-15
CN1759186A (zh) 2006-04-12
EP1581644A1 (en) 2005-10-05
ZA200504990B (en) 2006-08-30
JP2006517415A (ja) 2006-07-27
ES2287687T3 (es) 2007-12-16
US7169908B2 (en) 2007-01-30
DE602004006831T2 (de) 2008-02-14
US7579448B2 (en) 2009-08-25
KR20050095605A (ko) 2005-09-29
NZ540895A (en) 2007-03-30
US20070077625A1 (en) 2007-04-05
RU2005125210A (ru) 2006-01-10
EP1581644B1 (en) 2007-06-06
RU2337968C2 (ru) 2008-11-10
AU2004230670A1 (en) 2004-10-28
CA2511946A1 (en) 2004-10-28
BRPI0406470A (pt) 2005-12-06
AU2004230670B2 (en) 2010-11-25
CN100467611C (zh) 2009-03-11
US20050037456A1 (en) 2005-02-17
WO2004092393A1 (en) 2004-10-28

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