ES2189697B1 - Procedimiento para obtener nuevas formulaciones a base de luteina. - Google Patents

Procedimiento para obtener nuevas formulaciones a base de luteina.

Info

Publication number
ES2189697B1
ES2189697B1 ES200102917A ES200102917A ES2189697B1 ES 2189697 B1 ES2189697 B1 ES 2189697B1 ES 200102917 A ES200102917 A ES 200102917A ES 200102917 A ES200102917 A ES 200102917A ES 2189697 B1 ES2189697 B1 ES 2189697B1
Authority
ES
Spain
Prior art keywords
procedure
lutein
formulations
luteine
formulations based
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES200102917A
Other languages
English (en)
Other versions
ES2189697A1 (es
Inventor
Antonio Estrella De Castro
Nieves Fraile Yecora
Manuel Oliver Ruiz
Angel Muñoz
Juan Francisco Lopez Ortiz
Walter Cabri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Antibioticos SA
Original Assignee
Antibioticos SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8499898&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2189697(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Antibioticos SA filed Critical Antibioticos SA
Priority to ES200102917A priority Critical patent/ES2189697B1/es
Priority to AT02796800T priority patent/ATE402143T1/de
Priority to BRPI0215447A priority patent/BRPI0215447B1/pt
Priority to DE60227838T priority patent/DE60227838D1/de
Priority to MXPA04006282A priority patent/MXPA04006282A/es
Priority to US10/498,434 priority patent/US7045643B2/en
Priority to RU2004123095/04A priority patent/RU2303028C2/ru
Priority to PCT/ES2002/000609 priority patent/WO2003055855A1/es
Priority to ES02796800T priority patent/ES2310618T5/es
Priority to JP2003556387A priority patent/JP4437041B2/ja
Priority to EP02796800A priority patent/EP1460060B2/en
Priority to CA2471418A priority patent/CA2471418C/en
Priority to AU2002361273A priority patent/AU2002361273B2/en
Priority to CNB028264215A priority patent/CN1285574C/zh
Publication of ES2189697A1 publication Critical patent/ES2189697A1/es
Publication of ES2189697B1 publication Critical patent/ES2189697B1/es
Application granted granted Critical
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/24—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by six-membered non-aromatic rings, e.g. beta-carotene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Obesity (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nutrition Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Procedimiento para obtener nuevas formulaciones a base de luteína. La presente invención describe un procedimiento de preparación de formulaciones de luteína microcristalina, particularmente en forma de ésteres, estables a la oxidación y solubles en medios hidrofílicos y/o lipofílicos. Para ellos los ésteres de luteína se mezclan con antioxidantes, aceites vegetales y/o disolventes orgánicos, siendo esta mezcla inicial sometida a diversas etapas según el tipo de formulación que finalmente se desee obtener. Estas formulaciones son de aplicación directa como colorantes tanto en los campos farmacéutico, alimentario y en cosmética. Asimismo pueden utilizarse como suplementos nutricionales.
ES200102917A 2001-12-28 2001-12-28 Procedimiento para obtener nuevas formulaciones a base de luteina. Expired - Fee Related ES2189697B1 (es)

Priority Applications (14)

Application Number Priority Date Filing Date Title
ES200102917A ES2189697B1 (es) 2001-12-28 2001-12-28 Procedimiento para obtener nuevas formulaciones a base de luteina.
ES02796800T ES2310618T5 (es) 2001-12-28 2002-12-20 Procedimiento para obtener nuevas formulaciones a base de luteína.
EP02796800A EP1460060B2 (en) 2001-12-28 2002-12-20 Method of obtaining novel lutein-based formulations
DE60227838T DE60227838D1 (de) 2001-12-28 2002-12-20 Verfahren zum erhalten neuer formulierungen auf luteinbasis
MXPA04006282A MXPA04006282A (es) 2001-12-28 2002-12-20 Procedimiento para obtener nuevas formulaciones a base de luteina.
US10/498,434 US7045643B2 (en) 2001-12-28 2002-12-20 Method for obtaining novel lutein-based formulations
RU2004123095/04A RU2303028C2 (ru) 2001-12-28 2002-12-20 Способ получения композиции лютеина, композиции, их применение
PCT/ES2002/000609 WO2003055855A1 (es) 2001-12-28 2002-12-20 Procedimiento para obtener nuevas formulaciones a base de luteina
AT02796800T ATE402143T1 (de) 2001-12-28 2002-12-20 Verfahren zum erhalten neuer formulierungen auf luteinbasis
JP2003556387A JP4437041B2 (ja) 2001-12-28 2002-12-20 ルテインを基本とする新規処方物を得る方法
BRPI0215447A BRPI0215447B1 (pt) 2001-12-28 2002-12-20 método de obtenção de novas formulações à base de luteína
CA2471418A CA2471418C (en) 2001-12-28 2002-12-20 Method of obtaining novel lutein-based formulations
AU2002361273A AU2002361273B2 (en) 2001-12-28 2002-12-20 Method of obtaining novel lutein-based formulations
CNB028264215A CN1285574C (zh) 2001-12-28 2002-12-20 一种获得基于黄体素的新制剂的方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES200102917A ES2189697B1 (es) 2001-12-28 2001-12-28 Procedimiento para obtener nuevas formulaciones a base de luteina.

Publications (2)

Publication Number Publication Date
ES2189697A1 ES2189697A1 (es) 2003-07-01
ES2189697B1 true ES2189697B1 (es) 2005-02-01

Family

ID=8499898

Family Applications (2)

Application Number Title Priority Date Filing Date
ES200102917A Expired - Fee Related ES2189697B1 (es) 2001-12-28 2001-12-28 Procedimiento para obtener nuevas formulaciones a base de luteina.
ES02796800T Expired - Lifetime ES2310618T5 (es) 2001-12-28 2002-12-20 Procedimiento para obtener nuevas formulaciones a base de luteína.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES02796800T Expired - Lifetime ES2310618T5 (es) 2001-12-28 2002-12-20 Procedimiento para obtener nuevas formulaciones a base de luteína.

Country Status (13)

Country Link
US (1) US7045643B2 (es)
EP (1) EP1460060B2 (es)
JP (1) JP4437041B2 (es)
CN (1) CN1285574C (es)
AT (1) ATE402143T1 (es)
AU (1) AU2002361273B2 (es)
BR (1) BRPI0215447B1 (es)
CA (1) CA2471418C (es)
DE (1) DE60227838D1 (es)
ES (2) ES2189697B1 (es)
MX (1) MXPA04006282A (es)
RU (1) RU2303028C2 (es)
WO (1) WO2003055855A1 (es)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2000262820A1 (en) * 2000-07-13 2002-02-05 Rudolf Wild Gmbh And Co.Kg. Method for the production of a water-dispersible formulation containing carotenoids
DE20319249U1 (de) * 2003-12-10 2004-12-30 Aquanova German Solubilisate Technologies (Agt) Gmbh Lutein-Konzentrat
ATE501644T1 (de) * 2007-01-16 2011-04-15 Basf Se Flüssige formulierungen enthaltend carotinoide
DK2142011T3 (da) * 2007-02-23 2011-04-18 Brain Biotechnology Res & Information Network Ag Fremgangsmåde til smagsmodulering af stofsammensætninger, der indeholder mindst ét højintensitetssødemiddel (HIS)
MX2009008019A (es) * 2007-02-23 2009-08-07 Basf Se Uso de nanoparticulas carotenoides dispersibles en agua como moduladores de sabor, moduladores de sabor que contiene nanoparticulas carotenoides dispersibles en agua y metodo para modulacion de sabor.
EP1967081A1 (en) * 2007-03-05 2008-09-10 DSMIP Assets B.V. Process for the manufacture of a powder containing carotenoids
JP2008280281A (ja) * 2007-05-10 2008-11-20 Hokkaido Univ 抗肥満活性剤
US8158185B2 (en) * 2007-10-04 2012-04-17 Bunge Oils, Inc. Controlled viscosity oil composition and method of making
US20090118228A1 (en) * 2007-11-07 2009-05-07 Bristol-Myers Squibb Company Carotenoid-containing compositions and methods
US11185093B2 (en) * 2007-11-29 2021-11-30 Christian Köpsel Pulverulent carotenoid preparation for colouring drinks
CN101461450B (zh) * 2007-12-18 2011-12-28 浙江医药股份有限公司新昌制药厂 通过饮水补充动物体内类胡萝卜素的方法
WO2010040683A1 (de) 2008-10-07 2010-04-15 Basf Se Gebrauchfertige, stabile emulsion
WO2010094986A1 (en) * 2009-02-18 2010-08-26 Innova Andina S.A Micronized carotenoid preparation as immunostimulant for crustaceans
CN101921495B (zh) * 2009-06-12 2013-04-24 中国中化股份有限公司 一种制备叶黄素油树脂微胶囊的方法
PL2470606T3 (pl) * 2009-08-28 2014-04-30 Chr Hansen Natural Colors As Substancje węglowe o wysokiej sile barwienia
CN102329520B (zh) * 2011-07-08 2013-06-12 中国热带农业科学院农产品加工研究所 一种叶黄素纳米液的制备方法
KR101493564B1 (ko) * 2012-03-26 2015-02-16 우석대학교 산학협력단 루테인을 함유한 복합제제의 제조 방법
WO2014033703A1 (en) * 2012-08-26 2014-03-06 Lycored Ltd. HUE-CONTROLLED β-CAROTENE FORMULATIONS
HK1213151A1 (zh) * 2012-12-19 2016-06-30 Ew Nutrition Carotenoid Technologies Sa 叶黄素组合物及使用方法
EA029253B1 (ru) 2013-03-28 2018-02-28 ДСМ АйПи АССЕТС Б.В. Композиция лютеина, подходящая для составов детского питания
WO2015173603A1 (en) 2014-05-16 2015-11-19 Omniactive Health Technologies Limited Hydrophilic matrix beadlet compositions with enhanced bioavailability
CN105663082B (zh) * 2016-01-21 2018-06-22 江苏怀仁生物科技有限公司 一种强抗氧化性叶黄素微胶囊及其制备方法
CN108324699A (zh) * 2017-01-20 2018-07-27 浙江医药股份有限公司新昌制药厂 稳定的脂溶性活性成分组合物、微囊及其制备方法和应用
US11197493B2 (en) 2017-09-12 2021-12-14 Omniactive Health Technologies Limited Stabilized fat soluble nutrient compositions and process for the preparation thereof
DE102017009186A1 (de) 2017-09-25 2019-03-28 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Lutein und -derivate enthaltende Zusammensetzung sowie Verfahren zur Herstellung
CN108378112A (zh) * 2018-02-09 2018-08-10 云南瑞宝生物科技股份有限公司 含叶黄素酯的水果保健月饼及其制备方法
CN108077367A (zh) * 2018-02-09 2018-05-29 云南瑞宝生物科技股份有限公司 叶黄素酯饼干及其制备方法
TWI887201B (zh) * 2018-04-27 2025-06-21 荷蘭商帝斯曼知識產權資產管理有限公司 用於製備粉末之設置與方法及從其所獲得之組成物
US20230255898A1 (en) * 2019-10-15 2023-08-17 Omniactive Health Technologies Limited Xanthophyll composition comprising lutein and zeaxanthin with enhanced bioavailability
CN112704739A (zh) * 2020-12-29 2021-04-27 佛山市南海东方澳龙制药有限公司 一种叶黄素制剂的制备方法及叶黄素制剂
CN115153032B (zh) * 2022-05-25 2022-12-06 北京东方红航天生物技术股份有限公司 一种促进运动人群健康的组合物及其制备方法
KR102885420B1 (ko) 2022-09-07 2025-11-13 전북대학교산학협력단 크립토캅신과 루테인을 주성분으로 하는 복합 추출물 및 그의 제조방법
CN116059386B (zh) * 2023-03-27 2024-12-27 山东理工大学 一种水溶性叶黄素复合纳米颗粒及其制备方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3523138A (en) * 1965-03-01 1970-08-04 Eastman Kodak Co Treatment of marigold petal meal to obtain a xanthophyll product
US5382714A (en) * 1994-03-17 1995-01-17 The Catholic University Of America Process for isolation, purification, and recrystallization of lutein from saponified marigold oleoresin and uses thereof
US5648564A (en) * 1995-12-21 1997-07-15 Kemin Industries, Inc. Process for the formation, isolation and purification of comestible xanthophyll crystals from plants
EP0937412A1 (en) * 1998-02-23 1999-08-25 F. Hoffmann-La Roche Ag Preparation of a finely divided pulverous carotenoid preparation
US5968251A (en) * 1996-09-09 1999-10-19 Basf Aktiengesellschaft Production of carotenoid preparations in the form of coldwater-dispersible powders, and the use of the novel carotenoid preparations

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3523138A (en) * 1965-03-01 1970-08-04 Eastman Kodak Co Treatment of marigold petal meal to obtain a xanthophyll product
US5382714A (en) * 1994-03-17 1995-01-17 The Catholic University Of America Process for isolation, purification, and recrystallization of lutein from saponified marigold oleoresin and uses thereof
US5648564A (en) * 1995-12-21 1997-07-15 Kemin Industries, Inc. Process for the formation, isolation and purification of comestible xanthophyll crystals from plants
US5968251A (en) * 1996-09-09 1999-10-19 Basf Aktiengesellschaft Production of carotenoid preparations in the form of coldwater-dispersible powders, and the use of the novel carotenoid preparations
EP0937412A1 (en) * 1998-02-23 1999-08-25 F. Hoffmann-La Roche Ag Preparation of a finely divided pulverous carotenoid preparation

Also Published As

Publication number Publication date
CA2471418C (en) 2012-04-24
EP1460060B1 (en) 2008-07-23
DE60227838D1 (de) 2008-09-04
WO2003055855A1 (es) 2003-07-10
US7045643B2 (en) 2006-05-16
EP1460060A1 (en) 2004-09-22
CA2471418A1 (en) 2003-07-10
ATE402143T1 (de) 2008-08-15
AU2002361273B2 (en) 2008-06-12
CN1610662A (zh) 2005-04-27
BRPI0215447B1 (pt) 2015-12-22
US20050079223A1 (en) 2005-04-14
RU2004123095A (ru) 2005-05-10
CN1285574C (zh) 2006-11-22
RU2303028C2 (ru) 2007-07-20
ES2189697A1 (es) 2003-07-01
JP4437041B2 (ja) 2010-03-24
EP1460060B2 (en) 2011-08-31
BR0215447A (pt) 2005-04-05
ES2310618T5 (es) 2012-01-25
ES2310618T3 (es) 2009-01-16
MXPA04006282A (es) 2005-02-24
JP2005512587A (ja) 2005-05-12
AU2002361273A1 (en) 2003-07-15

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