ES2159354T3 - Preparado en gel oftalmologico esteril aplicable en gotas, y procedimiento para su obtencion. - Google Patents

Preparado en gel oftalmologico esteril aplicable en gotas, y procedimiento para su obtencion.

Info

Publication number
ES2159354T3
ES2159354T3 ES96904826T ES96904826T ES2159354T3 ES 2159354 T3 ES2159354 T3 ES 2159354T3 ES 96904826 T ES96904826 T ES 96904826T ES 96904826 T ES96904826 T ES 96904826T ES 2159354 T3 ES2159354 T3 ES 2159354T3
Authority
ES
Spain
Prior art keywords
drops
procedure
obtaining
prepared
gel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96904826T
Other languages
English (en)
Inventor
Gunther Bellmann
Gudrun Claus-Herz
Hevia Cornelia Reimer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dr Gerhard Mann Chem Pharm Fabrik GmbH
Original Assignee
Dr Gerhard Mann Chem Pharm Fabrik GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Gerhard Mann Chem Pharm Fabrik GmbH filed Critical Dr Gerhard Mann Chem Pharm Fabrik GmbH
Application granted granted Critical
Publication of ES2159354T3 publication Critical patent/ES2159354T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A61K31/78—Polymers containing oxygen of acrylic acid or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

LA INVENCION SE REFIERE A UNA PREPARACION OFTALMICA ESTERIL EN GOTAS, ESPECIALMENTE UNA PREPARACION DE GEL QUE TIENE UN FLUIDO VEHICULO O UNA BASE DE GEL BIFASICA QUE COMPRENDE UNA FASE ACUOSA LIQUIDA Y UNA FASE HIDROFOBA LIQUIDA.
ES96904826T 1995-03-28 1996-02-20 Preparado en gel oftalmologico esteril aplicable en gotas, y procedimiento para su obtencion. Expired - Lifetime ES2159354T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19511322A DE19511322C2 (de) 1995-03-28 1995-03-28 Sterile Augengele mit einem Gehalt an mittelkettigen Triglyceriden und Verfahren zu deren Herstellung

Publications (1)

Publication Number Publication Date
ES2159354T3 true ES2159354T3 (es) 2001-10-01

Family

ID=7757946

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96904826T Expired - Lifetime ES2159354T3 (es) 1995-03-28 1996-02-20 Preparado en gel oftalmologico esteril aplicable en gotas, y procedimiento para su obtencion.

Country Status (22)

Country Link
US (1) US6610318B1 (es)
EP (1) EP0817610B1 (es)
JP (2) JP3860609B2 (es)
KR (1) KR100384059B1 (es)
CN (1) CN1090476C (es)
AT (1) ATE201588T1 (es)
BR (1) BR9604878A (es)
CZ (1) CZ291002B6 (es)
DE (2) DE19511322C2 (es)
DK (1) DK0817610T3 (es)
ES (1) ES2159354T3 (es)
FI (1) FI119045B (es)
GR (1) GR3036418T3 (es)
HK (1) HK1010941A1 (es)
HU (1) HU222108B1 (es)
NO (1) NO316664B1 (es)
NZ (1) NZ328774A (es)
PL (1) PL184695B1 (es)
PT (1) PT817610E (es)
SI (1) SI9620048A (es)
SK (1) SK281594B6 (es)
WO (1) WO1996029984A1 (es)

Families Citing this family (21)

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JPH10218760A (ja) * 1997-02-04 1998-08-18 Nobel Igaku Kenkyusho:Kk ドライアイ治療用の微量油添加目薬
DE19938668B4 (de) * 1999-08-14 2006-01-26 Bausch & Lomb Inc. Tränenersatzmittel
AUPQ228199A0 (en) 1999-08-18 1999-09-09 Sly, Anthony William Ophthalmic fluid
JP2003520222A (ja) * 2000-01-20 2003-07-02 ドクトル ゲルハルト マン ケム−ファルム． ファブリック ゲゼルシャフト ミット ベシュレンクテル ハフツンク ジクロフェナミド懸濁液ゲル
DE10132876A1 (de) * 2001-07-06 2003-01-30 Medproject Pharma Entwicklungs Zweiphasige, tropfbare Hydrogele zur Anwendung am Auge
FR2835748B1 (fr) * 2002-02-14 2007-06-15 Veyron Et Froment Lab Composition ophtalmique sous forme d'emulsion
DE102005035986B4 (de) * 2005-07-28 2009-10-15 Bausch & Lomb Incorporated Steriles tropfbares mehrphasiges emulgatorfreies ophthalmisches Präparat
CN1883469B (zh) * 2006-05-26 2011-07-20 武汉远大制药集团有限公司 一种含有维生素a和维生素e的眼用微乳及其制备方法
DE102006049091A1 (de) * 2006-10-18 2008-04-24 Dr. Gerhard Mann Chem.-Pharm. Fabrik Gmbh Emulgatorfreies ophthalmisches Präparat enthaltend Pflanzenöl
GB2445539A (en) * 2006-12-29 2008-07-16 Ardana Bioscience Ltd Bigel composition
CN101028240B (zh) * 2007-03-29 2010-06-09 中国科学院上海药物研究所 眼用微乳/亚微乳原位凝胶制剂及其制备方法
FR2916636B1 (fr) 2007-05-29 2009-09-04 Octalia Technologies Vehicule sous forme d'une emulsion huile-dans-eau notamment destine a une utilisation ophtalmique ou dermocosmetique
US20120294898A1 (en) * 2011-05-19 2012-11-22 Warsaw Orthopedic, Inc. Injectable dbm for soft tissue repair
US8865685B2 (en) 2011-06-30 2014-10-21 Johnson & Johnson Vision Care, Inc. Esters for treatment of ocular inflammatory conditions
US11596599B2 (en) 2012-05-03 2023-03-07 The Johns Hopkins University Compositions and methods for ophthalmic and/or other applications
US9827191B2 (en) 2012-05-03 2017-11-28 The Johns Hopkins University Compositions and methods for ophthalmic and/or other applications
KR102140989B1 (ko) 2012-05-03 2020-08-04 칼라 파마슈티컬스, 인크. 개선된 점막 수송을 나타내는 제약 나노입자
EP3808339A1 (en) 2012-05-03 2021-04-21 Kala Pharmaceuticals, Inc. Pharmaceutical nanoparticles showing improved mucosal transport
PL3231417T3 (pl) * 2016-04-15 2019-05-31 Dr Gerhard Mann Chem Pharm Fabrik Gmbh Odporna na składowanie kompozycja oftalmiczna
EP3412276A3 (de) * 2017-06-09 2019-07-17 Omnivision GmbH Zusammensetzung zur behandlung des trockenen auges
TW201916892A (zh) * 2017-07-26 2019-05-01 一般財團法人阪大微生物病研究會 經無菌化之黏稠性基劑之製造方法及醫藥製劑之製造方法

Family Cites Families (24)

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Publication number Priority date Publication date Assignee Title
EP0028110B1 (en) * 1979-10-26 1984-03-07 Smith and Nephew Associated Companies p.l.c. Autoclavable emulsions
JPS57171912A (en) 1981-04-14 1982-10-22 Sumitomo Chem Co Ltd Cream
US4421748A (en) 1982-07-13 1983-12-20 Trager Seymour F Artificial tear aid
DE3440352A1 (de) * 1984-11-05 1986-05-07 Dr. Thilo & Co GmbH, 8029 Sauerlach Dry-eye-packung
JPS61130215A (ja) * 1984-11-28 1986-06-18 Santen Pharmaceut Co Ltd フルオロメトロンの水溶化方法
JPS61249918A (ja) * 1985-04-26 1986-11-07 Yutaka Mizushima 点眼剤
EP0316345A1 (en) 1986-07-28 1989-05-24 Liposome Technology, Inc. Liposomes with enhanced retention on mucosal tissue
US5032392A (en) * 1986-09-04 1991-07-16 Vision Pharmaceuticals Aqueous ophthalmic solutions for the treatment of dryness and/or irritation of human or animal eyes
US4966773A (en) * 1986-11-25 1990-10-30 Alcon Laboratories, Inc. Topical ophthalmic compositions containing microfine retinoid particles
US4914088A (en) 1987-04-02 1990-04-03 Thomas Glonek Dry eye treatment solution and method
US4866049A (en) 1987-08-10 1989-09-12 Spectra Pharmaceutical Services, Inc. Ophthalmic compositionn and method of using same
LU87416A1 (fr) * 1988-12-29 1990-07-10 Cird Microgranules charges en une substance active,constitues essentiellement d'un triglyceride d'acides gras satures et leur utilisation par voie topique dans le domaine therapeutique
CA2013755C (en) 1989-04-05 1993-11-30 Simon Benita Medicinal emulsions
EP0459148B1 (en) 1990-05-29 1996-01-03 Ocular Research Of Boston Inc. Dry eye treatment composition
US5252318A (en) 1990-06-15 1993-10-12 Allergan, Inc. Reversible gelation compositions and methods of use
IL98747A0 (en) * 1991-07-05 1992-07-15 Yissum Res Dev Co Ophthalmic compositions
FR2679135B1 (fr) * 1991-07-18 1995-05-19 Europhta Sa Laboratoire Nouvelles compositions ophtalmiques a adhesivite amelioree et leurs procedes de preparation.
JP3072340B2 (ja) * 1991-10-21 2000-07-31 ポーラ化成工業株式会社 水性目薬及びその製造法
FR2690846B1 (fr) 1992-05-05 1995-07-07 Aiache Jean Marc Forme galenique pour administration oculaire et procede de preparation.
ATE191641T1 (de) 1992-08-28 2000-04-15 Pharmos Corp Emulsionen im submikron-bereich als vehikel zur arzneistoffverabreichung am auge
AU673885B2 (en) * 1992-12-29 1996-11-28 Insite Vision Incorporated Bioerodible controlled delivery system
WO1994023750A1 (en) 1993-04-16 1994-10-27 Wakamoto Pharmaceutical Co., Ltd. Reversible, thermally gelling water-base medicinal composition
JP3438264B2 (ja) * 1993-07-07 2003-08-18 ライオン株式会社 安定なビタミンａ類可溶化水性点眼剤の調製方法
US5744155A (en) * 1993-08-13 1998-04-28 Friedman; Doron Bioadhesive emulsion preparations for enhanced drug delivery

Also Published As

Publication number Publication date
DE19511322A1 (de) 1996-10-02
DE59607005D1 (de) 2001-07-05
NO974450D0 (no) 1997-09-26
JPH10508316A (ja) 1998-08-18
HUP9801243A2 (hu) 1998-09-28
US6610318B1 (en) 2003-08-26
PL184695B1 (pl) 2002-12-31
JP3860609B2 (ja) 2006-12-20
FI973797A (fi) 1997-09-26
KR19980703301A (ko) 1998-10-15
KR100384059B1 (ko) 2003-10-11
AU722820B2 (en) 2000-08-10
NZ328774A (en) 1999-09-29
PL324620A1 (en) 1998-06-08
WO1996029984A1 (de) 1996-10-03
EP0817610B1 (de) 2001-05-30
JP4729364B2 (ja) 2011-07-20
JP2005325141A (ja) 2005-11-24
HK1010941A1 (en) 1999-07-02
NO316664B1 (no) 2004-03-29
SI9620048A (sl) 1998-04-30
SK131497A3 (en) 1998-06-03
PT817610E (pt) 2001-11-30
FI119045B (fi) 2008-07-15
BR9604878A (pt) 1999-11-30
CN1090476C (zh) 2002-09-11
CN1189773A (zh) 1998-08-05
AU3928497A (en) 1999-05-10
CZ295297A3 (cs) 1998-03-18
SK281594B6 (sk) 2001-05-10
GR3036418T3 (en) 2001-11-30
DK0817610T3 (da) 2001-09-10
NO974450L (no) 1997-09-26
HU222108B1 (hu) 2003-04-28
ATE201588T1 (de) 2001-06-15
DE19511322C2 (de) 1999-09-02
HUP9801243A3 (en) 2001-03-28
CZ291002B6 (cs) 2002-11-13
EP0817610A1 (de) 1998-01-14
FI973797A0 (fi) 1997-09-26

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