ES2179308T3 - Preparacion farmaceutica en forma de gel aplicable a superficies d e las mucosas y a los tejidos corporales. - Google Patents
Preparacion farmaceutica en forma de gel aplicable a superficies d e las mucosas y a los tejidos corporales.Info
- Publication number
- ES2179308T3 ES2179308T3 ES97910118T ES97910118T ES2179308T3 ES 2179308 T3 ES2179308 T3 ES 2179308T3 ES 97910118 T ES97910118 T ES 97910118T ES 97910118 T ES97910118 T ES 97910118T ES 2179308 T3 ES2179308 T3 ES 2179308T3
- Authority
- ES
- Spain
- Prior art keywords
- body tissues
- mucouses
- gel
- pharmaceutical preparation
- residence time
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Nutrition Science (AREA)
- Anesthesiology (AREA)
- Virology (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Endocrinology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Materials For Medical Uses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
LA INVENCION SE REFIERE A UN GEL PORTADOR DE PRODUCTOS FARMACEUTICOS, SOLUBLE EN AGUA QUE SE ADHIERE A LA SUPERFICIE DE LAS MUCOSAS Y A LOS TEJIDOS CORPORALES DESPUES DE SU APLICACION Y FORMA UNA PELICULA QUE SUMINISTRA PROTECCION Y ADMINISTRA EL PRODUCTO FARMACEUTICA A LA ZONA DE APLICACION, ASI COMO A LOS TEJIDOS CORPORALES CIRCUNDANTES Y A LOS FLUIDOS CORPORALES. EL GEL COMPRENDE UN SOLVENTE NO ACUOSO VOLATIL O DIFUSOR Y AL MENOS UNA CELULOSA DE ALQUILO O UNA CELULOSA DE HIDROXIALQUILO NO SOLUBLE EN AGUA. TAMBIEN PUEDE AÑADIRSE UN POLIMERO BIOADHESIVO. EL GEL SUMINISTRA UN TIEMPO DE RESIDENCIA EFECTIVO Y ES DE FACIL EMPLEO. EL TIEMPO DE RESIDENCIA PUEDE AJUSTARSE AÑADIENDO UN COMPONENTE QUE ACTUE PARA AJUSTAR LA CINETICA DE LA CAPACIDAD DE EROSION DEL PORTADOR.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/733,454 US5955097A (en) | 1996-10-18 | 1996-10-18 | Pharmaceutical preparation applicable to mucosal surfaces and body tissues |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2179308T3 true ES2179308T3 (es) | 2003-01-16 |
Family
ID=24947672
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES02004079T Expired - Lifetime ES2272586T3 (es) | 1996-10-18 | 1997-10-16 | Preparacion con vehiculo farmaceutico aplicable a superficies de mucosas. |
ES97910118T Expired - Lifetime ES2179308T3 (es) | 1996-10-18 | 1997-10-16 | Preparacion farmaceutica en forma de gel aplicable a superficies d e las mucosas y a los tejidos corporales. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES02004079T Expired - Lifetime ES2272586T3 (es) | 1996-10-18 | 1997-10-16 | Preparacion con vehiculo farmaceutico aplicable a superficies de mucosas. |
Country Status (11)
Country | Link |
---|---|
US (2) | US5955097A (es) |
EP (2) | EP0930873B1 (es) |
JP (2) | JP2001508038A (es) |
AT (2) | ATE223699T1 (es) |
AU (1) | AU731645B2 (es) |
CA (1) | CA2268140C (es) |
DE (2) | DE69715433T2 (es) |
DK (2) | DK1210934T3 (es) |
ES (2) | ES2272586T3 (es) |
PT (2) | PT930873E (es) |
WO (1) | WO1998017252A1 (es) |
Families Citing this family (89)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5955097A (en) * | 1996-10-18 | 1999-09-21 | Virotex Corporation | Pharmaceutical preparation applicable to mucosal surfaces and body tissues |
US6153210A (en) * | 1997-08-14 | 2000-11-28 | Periodontix, Inc. | Use of locally delivered metal ions for treatment of periodontal disease |
TWI243687B (en) | 1998-04-21 | 2005-11-21 | Teijin Ltd | Pharmaceutical composition for application to mucosa |
CA2306486C (en) * | 1998-10-19 | 2008-12-09 | Zila, Inc. | Method and compositions for in situ formation of protective and/or medicated films on body tissue |
DE19925519A1 (de) | 1999-06-04 | 2000-12-07 | Lohmann Therapie Syst Lts | Wundauflage zur gesteuerten Abgabe von Wirkstoff an Wunden und Verfahren zu ihrer Herstellung |
US6375963B1 (en) | 1999-06-16 | 2002-04-23 | Michael A. Repka | Bioadhesive hot-melt extruded film for topical and mucosal adhesion applications and drug delivery and process for preparation thereof |
AR026073A1 (es) | 1999-10-20 | 2002-12-26 | Nycomed Gmbh | Composicion farmaceutica acuosa que contiene ciclesonida |
ATE494908T1 (de) | 1999-10-26 | 2011-01-15 | Novartis Vaccines & Diagnostic | Pflanzen lektine als mukosale adjuvantien |
US6863896B1 (en) * | 1999-10-26 | 2005-03-08 | Chiron Corporation | Plant lectins as mucosal adjuvants |
US6555125B2 (en) * | 1999-11-30 | 2003-04-29 | Phillip Campbell | Lesion and ulcer medication |
US6706781B2 (en) * | 1999-12-08 | 2004-03-16 | The Procter & Gamble Company | Denture adhesive compositions with antimicrobial agents |
US6432415B1 (en) * | 1999-12-17 | 2002-08-13 | Axrix Laboratories, Inc. | Pharmaceutical gel and aerosol formulations and methods to administer the same to skin and mucosal surfaces |
US20020013331A1 (en) * | 2000-06-26 | 2002-01-31 | Williams Robert O. | Methods and compositions for treating pain of the mucous membrane |
US7803392B2 (en) | 2000-12-27 | 2010-09-28 | University Of Kentucky Research Foundation | pH-Sensitive mucoadhesive film-forming gels and wax-film composites suitable for topical and mucosal delivery of molecules |
US20030017133A1 (en) * | 2001-06-15 | 2003-01-23 | Wyeth (Formerly American Home Products Corporation) | Mucoadhesive composition |
US7015253B2 (en) * | 2001-07-10 | 2006-03-21 | American Medical Systems, Inc. | Regimen for treating prostate tissue and surgical kit for use in the regimen |
US20060073174A1 (en) * | 2001-08-16 | 2006-04-06 | Access Pharmaceuticals, Inc. | Adherent and erodible film to treat a moist surface of a body tissue |
US6585997B2 (en) | 2001-08-16 | 2003-07-01 | Access Pharmaceuticals, Inc. | Mucoadhesive erodible drug delivery device for controlled administration of pharmaceuticals and other active compounds |
US11207805B2 (en) | 2001-10-12 | 2021-12-28 | Aquestive Therapeutics, Inc. | Process for manufacturing a resulting pharmaceutical film |
US20070281003A1 (en) | 2001-10-12 | 2007-12-06 | Fuisz Richard C | Polymer-Based Films and Drug Delivery Systems Made Therefrom |
US8603514B2 (en) | 2002-04-11 | 2013-12-10 | Monosol Rx, Llc | Uniform films for rapid dissolve dosage form incorporating taste-masking compositions |
US8765167B2 (en) | 2001-10-12 | 2014-07-01 | Monosol Rx, Llc | Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions |
US8900497B2 (en) | 2001-10-12 | 2014-12-02 | Monosol Rx, Llc | Process for making a film having a substantially uniform distribution of components |
US7357891B2 (en) | 2001-10-12 | 2008-04-15 | Monosol Rx, Llc | Process for making an ingestible film |
US10285910B2 (en) | 2001-10-12 | 2019-05-14 | Aquestive Therapeutics, Inc. | Sublingual and buccal film compositions |
US20110033542A1 (en) | 2009-08-07 | 2011-02-10 | Monosol Rx, Llc | Sublingual and buccal film compositions |
US8900498B2 (en) | 2001-10-12 | 2014-12-02 | Monosol Rx, Llc | Process for manufacturing a resulting multi-layer pharmaceutical film |
US20190328679A1 (en) | 2001-10-12 | 2019-10-31 | Aquestive Therapeutics, Inc. | Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions |
US8425892B2 (en) | 2001-10-29 | 2013-04-23 | Columbia Laboratories, Inc. | Extended, controlled-release pharmaceutical compositions using charged polymers |
US20030118655A1 (en) * | 2001-12-21 | 2003-06-26 | Nikhil Kundel | Film forming liquid composition |
DE10302424B4 (de) * | 2002-01-25 | 2005-04-28 | Pms Handelskontor Gmbh | Haftmittel für ein Zahnprothese |
US20030175360A1 (en) * | 2002-02-22 | 2003-09-18 | Renzo Luzzatti | Symptomatic relief of gastrointestinal disorders |
US20040028744A1 (en) * | 2002-06-17 | 2004-02-12 | Sauwaluxana Tongaree | Mucoadhesive composition |
AU2002950506A0 (en) * | 2002-07-31 | 2002-09-12 | Soltec Research Pty Ltd | Percutaneous delivery system |
US20040151771A1 (en) * | 2003-02-04 | 2004-08-05 | Gin Jerry B. | Long-lasting, flavored dosage forms for sustained release of beneficial agents within the mouth |
AU2004264974A1 (en) * | 2003-08-15 | 2005-02-24 | Arius Two, Inc. | Adhesive bioerodible transmucosal drug delivery system |
WO2005027939A1 (en) * | 2003-08-21 | 2005-03-31 | Access Pharmaceuticals, Inc. | Liquid formulations for the prevention and treatment of mucosal diseases and disorders |
US20070196452A1 (en) * | 2004-06-07 | 2007-08-23 | Jie Zhang | Flux-enabling compositions and methods for dermal delivery of drugs |
US20070196293A1 (en) * | 2004-06-07 | 2007-08-23 | Jie Zhang | Compositions and methods for treating photo damaged skin |
US20070196453A1 (en) * | 2004-06-07 | 2007-08-23 | Jie Zhang | Two or more non-volatile solvent-containing compositions and methods for dermal delivery of drugs |
US8741333B2 (en) | 2004-06-07 | 2014-06-03 | Nuvo Research Inc. | Compositions and methods for treating dermatitis or psoriasis |
US20070196323A1 (en) * | 2004-06-07 | 2007-08-23 | Jie Zhang | Polyvinyl alcohol-containing compositions and methods for dermal delivery of drugs |
US8907153B2 (en) | 2004-06-07 | 2014-12-09 | Nuvo Research Inc. | Adhesive peel-forming formulations for dermal delivery of drugs and methods of using the same |
US8741332B2 (en) * | 2004-06-07 | 2014-06-03 | Nuvo Research Inc. | Compositions and methods for dermally treating neuropathic pain |
US20080019927A1 (en) * | 2004-06-07 | 2008-01-24 | Jie Zhang | Compositions and methods for dermally treating neuropathy with minoxidil |
US20070196325A1 (en) * | 2004-06-07 | 2007-08-23 | Jie Zhang | Compositions and methods for dermally treating infections |
US20070189978A1 (en) * | 2004-06-07 | 2007-08-16 | Jie Zhang | Compositions and methods for dermally treating musculoskeletal pain |
US20070190124A1 (en) * | 2004-06-07 | 2007-08-16 | Jie Zhang | Two or more solidifying agent-containing compositions and methods for dermal delivery of drugs |
US20070196457A1 (en) * | 2004-06-07 | 2007-08-23 | Jie Zhang | Two or more volatile solvent-containing compositions and methods for dermal delivery of drugs |
WO2006026504A2 (en) * | 2004-08-27 | 2006-03-09 | Spherics, Inc. | Mucoadhesive oral formulations of high permeability, high solubility drugs |
CN101076317A (zh) * | 2004-11-01 | 2007-11-21 | 瑞拉医药公司 | 减少医院内感染的方法 |
DE102005059420B4 (de) * | 2004-12-09 | 2008-11-20 | Axel Hensel | Verwendung einer Hypromellose enthaltende zu einer Buccaltablette gepressten Haftpaste zur Behandlung lokaler Erkrankungen der Mundschleimhaut |
MX2007006732A (es) * | 2004-12-16 | 2007-08-06 | Hercules Inc | Composiciones para el cuidado personal y domestico de polisacaridos modificados hidrofobicamente. |
US7252834B2 (en) * | 2005-04-25 | 2007-08-07 | Clemson University Research Foundation (Curf) | Elastin stabilization of connective tissue |
DE102005033943A1 (de) * | 2005-07-20 | 2007-02-22 | Hexal Ag | Nicht-ausspuckbarer, oraler, schnell-zerfallender Film für ein Neuroleptikum |
US20070225632A1 (en) * | 2006-03-21 | 2007-09-27 | David Rauser | Hydratable polymeric ester matrix for drug electrotransport |
US20070280972A1 (en) * | 2006-04-25 | 2007-12-06 | Zars, Inc. | Adhesive solid gel-forming formulations for dermal drug delivery |
US20070298087A1 (en) * | 2006-06-27 | 2007-12-27 | Biegajski James E | Two-phase mucoadhesive composition |
US10265265B2 (en) | 2007-03-15 | 2019-04-23 | Drug Delivery Solutions Limited | Topical composition |
EP2008651A1 (en) * | 2007-06-26 | 2008-12-31 | Drug Delivery Solutions Limited | A bioerodible patch |
HU227970B1 (en) | 2007-07-10 | 2012-07-30 | Egis Gyogyszergyar Nyrt | Pharmaceutical compositions containing silicones of high volatility |
AU2008289109B2 (en) * | 2007-08-17 | 2012-02-02 | Centrexion Therapeutics Corporation | High concentration local anesthetic formulations |
US20090081294A1 (en) * | 2007-09-26 | 2009-03-26 | Gin Jerry B | Sustained release dosage form for lubricating an oral cavity |
US20090081291A1 (en) * | 2007-09-26 | 2009-03-26 | Gin Jerry B | Sustained Release Dosage Forms For Delivery of Agents to an Oral Cavity of a User |
MX2010007282A (es) * | 2007-12-31 | 2010-11-12 | Acclarent Inc | Aposito para el tejido mucoso y metodo de uso. |
US20090214654A1 (en) * | 2008-02-21 | 2009-08-27 | Isenburg Jason C | Treatment of aneurysm with application of connective tissue stabilization agent in combination with a delivery vehicle |
EP2143421A1 (en) * | 2008-07-07 | 2010-01-13 | Almirall Hermal GmbH | Topical composition for the treatment of actinic keratosis |
US20100016833A1 (en) * | 2008-07-15 | 2010-01-21 | Ogle Matthew F | Devices for the Treatment of Vascular Aneurysm |
WO2010019953A1 (en) | 2008-08-15 | 2010-02-18 | Arcion Therapeutics, Inc. | High concentration local anesthetic formulations for treating non-neuropathic pain |
US20100119605A1 (en) * | 2008-11-12 | 2010-05-13 | Isenburg Jason C | Compositions for tissue stabilization |
US8741267B1 (en) | 2009-06-26 | 2014-06-03 | Joseph P. Trovato | Method for treating periodontal disease |
US8496911B2 (en) * | 2009-07-29 | 2013-07-30 | Vatrix CHF, Inc. | Tissue stabilization for heart failure |
WO2011044455A1 (en) * | 2009-10-09 | 2011-04-14 | Vatrix Medical, Inc. | In vivo chemical stabilization of vulnerable plaque |
US8444624B2 (en) * | 2009-10-19 | 2013-05-21 | Vatrix Medical, Inc. | Vascular medical devices with sealing elements and procedures for the treatment of isolated vessel sections |
EP2504019A2 (en) | 2009-11-25 | 2012-10-03 | ArisGen SA | Mucosal delivery composition comprising a peptide complexed with a crown compound and/or a counter ion |
US8337870B2 (en) | 2009-12-15 | 2012-12-25 | Young Pharmaceuticals, Inc. | Low toxicity topical active agent delivery system |
US9149959B2 (en) | 2010-10-22 | 2015-10-06 | Monosol Rx, Llc | Manufacturing of small film strips |
US8911468B2 (en) | 2011-01-31 | 2014-12-16 | Vatrix Medical, Inc. | Devices, therapeutic compositions and corresponding percutaneous treatment methods for aortic dissection |
RU2639472C2 (ru) | 2011-03-14 | 2017-12-21 | Драг Деливери Солюшнз Лимитед | Офтальмическая композиция |
WO2012158944A1 (en) | 2011-05-18 | 2012-11-22 | Vatrix Medical, Inc. | Coated balloons for blood vessel stabilization |
ES2375784B1 (es) * | 2011-12-22 | 2013-01-24 | Laboratorios Kin S.A. | Gel de ácido tranexámico |
US10045935B2 (en) | 2012-07-31 | 2018-08-14 | Egis Pharmaceuticals Plc | Transdermal formulation containing COX inhibitors |
US10045965B2 (en) | 2012-07-31 | 2018-08-14 | Egis Pharmaceuticals Plc | Transdermal formulation containing COX inhibitors |
US11154535B2 (en) | 2012-07-31 | 2021-10-26 | Egis Pharmaceuticals Plc | Transdermal formulation containing COX inhibitors |
WO2014198999A1 (en) * | 2013-06-13 | 2014-12-18 | Opes Corporation Oy | Matrix |
US11273131B2 (en) | 2016-05-05 | 2022-03-15 | Aquestive Therapeutics, Inc. | Pharmaceutical compositions with enhanced permeation |
KR20230137362A (ko) | 2016-05-05 | 2023-10-04 | 어퀘스티브 테라퓨틱스, 아이엔씨. | 강화된 전달 에프네프린 조성물 |
EP3542788A1 (en) | 2018-03-19 | 2019-09-25 | MC2 Therapeutics Limited | Topical composition comprising calcipotriol and betamethasone dipropionate |
CN117298071A (zh) * | 2023-11-13 | 2023-12-29 | 力品药业(厦门)股份有限公司 | 一种用于治疗口腔溃疡的口腔贴膜及其制备方法 |
Family Cites Families (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE626627A (es) * | 1962-04-26 | |||
US3640741A (en) * | 1970-02-24 | 1972-02-08 | Hollister Inc | Composition containing gel |
US3755558A (en) * | 1971-02-23 | 1973-08-28 | Du Pont | Polylactide drug mixtures for topical application atelet aggregation |
US3996934A (en) * | 1971-08-09 | 1976-12-14 | Alza Corporation | Medical bandage |
JPS5562012A (en) * | 1978-11-06 | 1980-05-10 | Teijin Ltd | Slow-releasing preparation |
GB2042888B (en) * | 1979-03-05 | 1983-09-28 | Teijin Ltd | Preparation for administration to the mucosa of the oral or nasal cavity |
US4285934A (en) * | 1979-07-13 | 1981-08-25 | Tinnell James E | Treatment for herpes virus |
JPS56100714A (en) * | 1980-01-16 | 1981-08-12 | Teijin Ltd | Pharmaceutical adhering to oral mucous membrane or nasal mucous membrane |
US4286592A (en) * | 1980-02-04 | 1981-09-01 | Alza Corporation | Therapeutic system for administering drugs to the skin |
US4381296A (en) * | 1980-06-23 | 1983-04-26 | Tinnell James E | Treatment for herpes virus |
JPS5758615A (en) * | 1980-09-26 | 1982-04-08 | Nippon Soda Co Ltd | Film agnent and its preparation |
US4518721A (en) * | 1982-03-26 | 1985-05-21 | Richardson-Vicks Inc. | Hydrophilic denture adhesive |
CA1208558A (en) * | 1982-10-07 | 1986-07-29 | Kazuo Kigasawa | Soft buccal |
ATE95430T1 (de) * | 1984-12-22 | 1993-10-15 | Sanol Arznei Schwarz Gmbh | Wirkstoffpflaster. |
US4713243A (en) * | 1986-06-16 | 1987-12-15 | Johnson & Johnson Products, Inc. | Bioadhesive extruded film for intra-oral drug delivery and process |
US4906463A (en) * | 1986-12-22 | 1990-03-06 | Cygnus Research Corporation | Transdermal drug-delivery composition |
JPH0744940B2 (ja) * | 1986-12-24 | 1995-05-17 | ライオン株式会社 | 口腔貼付用基材 |
DE3714074A1 (de) * | 1987-04-28 | 1988-11-10 | Hoechst Ag | Grundlage fuer schleimhaut- und prothesenhaft-pasten, verfahren zu ihrer herstellung sowie pasten auf basis dieser grundlage |
EP0289900A1 (en) * | 1987-04-30 | 1988-11-09 | Abbott Laboratories | Topical antibacterial compositions |
US4867970A (en) * | 1987-05-21 | 1989-09-19 | E. R. Squibb & Sons, Inc. | Moistureless oral drug delivery formulation and method for preparing same |
US4915948A (en) * | 1987-08-31 | 1990-04-10 | Warner-Lambert Company | Tablets having improved bioadhesion to mucous membranes |
US5059189A (en) * | 1987-09-08 | 1991-10-22 | E. R. Squibb & Sons, Inc. | Method of preparing adhesive dressings containing a pharmaceutically active ingredient |
JPH01151516A (ja) * | 1987-12-08 | 1989-06-14 | Shionogi & Co Ltd | ビタミンe配合外用剤 |
JPH07116035B2 (ja) * | 1987-12-08 | 1995-12-13 | 塩野義製薬株式会社 | 被膜形成性抗真菌剤組成物 |
US5081158A (en) * | 1988-05-02 | 1992-01-14 | Zila Pharmaceuticals, Inc. | Compositions and in situ methods for forming films on body tissue |
US5081157A (en) * | 1988-05-02 | 1992-01-14 | Zila Pharmaceuticals, Inc. | Compositions and in situ methods for forming films on body tissue |
JPH0645536B2 (ja) * | 1989-01-31 | 1994-06-15 | 日東電工株式会社 | 口腔粘膜貼付剤および口腔粘膜貼付製剤 |
JP2656338B2 (ja) * | 1989-01-31 | 1997-09-24 | 日東電工株式会社 | 口腔粘膜貼付製剤 |
US5298258A (en) * | 1989-12-28 | 1994-03-29 | Nitto Denko Corporation | Acrylic oily gel bioadhesive material and acrylic oily gel preparation |
US5192802A (en) * | 1991-09-25 | 1993-03-09 | Mcneil-Ppc, Inc. | Bioadhesive pharmaceutical carrier |
JP2533723B2 (ja) * | 1992-12-28 | 1996-09-11 | 東興薬品工業株式会社 | 速乾性ゲルタイプ手指消毒剤 |
US5540930A (en) * | 1993-10-25 | 1996-07-30 | Pharmos Corporation | Suspension of loteprednol etabonate for ear, eye, or nose treatment |
FR2732223B1 (fr) * | 1995-03-30 | 1997-06-13 | Sanofi Sa | Composition pharmaceutique pour administration transdermique |
US5955097A (en) * | 1996-10-18 | 1999-09-21 | Virotex Corporation | Pharmaceutical preparation applicable to mucosal surfaces and body tissues |
US5885611A (en) | 1997-06-04 | 1999-03-23 | Colgate-Palmolive Company | Bandage-forming gel for oral mucosa |
-
1996
- 1996-10-18 US US08/733,454 patent/US5955097A/en not_active Expired - Lifetime
-
1997
- 1997-10-16 WO PCT/US1997/018606 patent/WO1998017252A1/en active IP Right Grant
- 1997-10-16 EP EP97910118A patent/EP0930873B1/en not_active Expired - Lifetime
- 1997-10-16 ES ES02004079T patent/ES2272586T3/es not_active Expired - Lifetime
- 1997-10-16 AU AU47575/97A patent/AU731645B2/en not_active Ceased
- 1997-10-16 DK DK02004079T patent/DK1210934T3/da active
- 1997-10-16 PT PT97910118T patent/PT930873E/pt unknown
- 1997-10-16 ES ES97910118T patent/ES2179308T3/es not_active Expired - Lifetime
- 1997-10-16 AT AT97910118T patent/ATE223699T1/de active
- 1997-10-16 DE DE69715433T patent/DE69715433T2/de not_active Expired - Lifetime
- 1997-10-16 AT AT02004079T patent/ATE338537T1/de active
- 1997-10-16 PT PT02004079T patent/PT1210934E/pt unknown
- 1997-10-16 CA CA002268140A patent/CA2268140C/en not_active Expired - Fee Related
- 1997-10-16 DK DK97910118T patent/DK0930873T3/da active
- 1997-10-16 EP EP02004079A patent/EP1210934B1/en not_active Expired - Lifetime
- 1997-10-16 JP JP51946898A patent/JP2001508038A/ja not_active Withdrawn
- 1997-10-16 DE DE69736641T patent/DE69736641T2/de not_active Expired - Lifetime
-
1999
- 1999-07-30 US US09/364,566 patent/US6290984B1/en not_active Expired - Lifetime
-
2007
- 2007-05-25 JP JP2007139731A patent/JP2007211030A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
DK0930873T3 (da) | 2002-11-18 |
CA2268140A1 (en) | 1998-04-30 |
ATE223699T1 (de) | 2002-09-15 |
DE69715433D1 (de) | 2002-10-17 |
PT1210934E (pt) | 2006-12-29 |
EP0930873A1 (en) | 1999-07-28 |
JP2007211030A (ja) | 2007-08-23 |
US5955097A (en) | 1999-09-21 |
JP2001508038A (ja) | 2001-06-19 |
CA2268140C (en) | 2005-05-24 |
ATE338537T1 (de) | 2006-09-15 |
WO1998017252A1 (en) | 1998-04-30 |
EP1210934B1 (en) | 2006-09-06 |
DE69736641T2 (de) | 2007-09-13 |
ES2272586T3 (es) | 2007-05-01 |
AU731645B2 (en) | 2001-04-05 |
EP1210934A3 (en) | 2003-01-08 |
PT930873E (pt) | 2003-01-31 |
EP1210934A2 (en) | 2002-06-05 |
DK1210934T3 (da) | 2007-01-15 |
DE69736641D1 (de) | 2006-10-19 |
AU4757597A (en) | 1998-05-15 |
EP0930873B1 (en) | 2002-09-11 |
US6290984B1 (en) | 2001-09-18 |
DE69715433T2 (de) | 2003-01-09 |
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