HUP9801243A2 - Steril, csepegtethető szemészeti gélkészítmény és eljárás az előállítására - Google Patents
Steril, csepegtethető szemészeti gélkészítmény és eljárás az előállításáraInfo
- Publication number
- HUP9801243A2 HUP9801243A2 HU9801243A HUP9801243A HUP9801243A2 HU P9801243 A2 HUP9801243 A2 HU P9801243A2 HU 9801243 A HU9801243 A HU 9801243A HU P9801243 A HUP9801243 A HU P9801243A HU P9801243 A2 HUP9801243 A2 HU P9801243A2
- Authority
- HU
- Hungary
- Prior art keywords
- sterile
- drops
- producing
- gel preparation
- gel
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000000499 gel Substances 0.000 abstract 3
- 239000008346 aqueous phase Substances 0.000 abstract 2
- 230000002209 hydrophobic effect Effects 0.000 abstract 2
- 239000012071 phase Substances 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 230000002051 biphasic effect Effects 0.000 abstract 1
- 239000000017 hydrogel Substances 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/765—Polymers containing oxygen
- A61K31/78—Polymers containing oxygen of acrylic acid or derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
A találmány tárgya steril, csepegtethető szemészeti készítmény,különösen gélkészítmény, amely egy kétfázisú, egy főlyékőny vizesfázist és egy főlyékőny hidrőfób fázist magában főglalóhőrdőzófőlyadékőt, illetve gélbázist tartalmaz és eműlgátőrmentes. A találmány tárgya tővábbá eljárás a készítmény előállítására,amelynek értelmében egy főlyékőny hidrőfób fázist, különösen egyközepes szénláncú triglicerid kőmpőnenst egy főlytőnős vizes fázisban,különösen egy előre előállítőtt steril hidrőgélben hőmőgénendiszpergálnak. ŕ
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19511322A DE19511322C2 (de) | 1995-03-28 | 1995-03-28 | Sterile Augengele mit einem Gehalt an mittelkettigen Triglyceriden und Verfahren zu deren Herstellung |
PCT/EP1996/000697 WO1996029984A1 (de) | 1995-03-28 | 1996-02-20 | Steriles tropfbares ophthalmisches gelpräparat und verfahren zu dessen herstellung |
Publications (3)
Publication Number | Publication Date |
---|---|
HUP9801243A2 true HUP9801243A2 (hu) | 1998-09-28 |
HUP9801243A3 HUP9801243A3 (en) | 2001-03-28 |
HU222108B1 HU222108B1 (hu) | 2003-04-28 |
Family
ID=7757946
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU9801243A HU222108B1 (hu) | 1995-03-28 | 1996-02-20 | Steril, csepegtethető szemészeti gélkészítmény és eljárás az előállítására |
Country Status (22)
Country | Link |
---|---|
US (1) | US6610318B1 (hu) |
EP (1) | EP0817610B1 (hu) |
JP (2) | JP3860609B2 (hu) |
KR (1) | KR100384059B1 (hu) |
CN (1) | CN1090476C (hu) |
AT (1) | ATE201588T1 (hu) |
BR (1) | BR9604878A (hu) |
CZ (1) | CZ291002B6 (hu) |
DE (2) | DE19511322C2 (hu) |
DK (1) | DK0817610T3 (hu) |
ES (1) | ES2159354T3 (hu) |
FI (1) | FI119045B (hu) |
GR (1) | GR3036418T3 (hu) |
HK (1) | HK1010941A1 (hu) |
HU (1) | HU222108B1 (hu) |
NO (1) | NO316664B1 (hu) |
NZ (1) | NZ328774A (hu) |
PL (1) | PL184695B1 (hu) |
PT (1) | PT817610E (hu) |
SI (1) | SI9620048A (hu) |
SK (1) | SK281594B6 (hu) |
WO (1) | WO1996029984A1 (hu) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH10218760A (ja) * | 1997-02-04 | 1998-08-18 | Nobel Igaku Kenkyusho:Kk | ドライアイ治療用の微量油添加目薬 |
DE19938668B4 (de) * | 1999-08-14 | 2006-01-26 | Bausch & Lomb Inc. | Tränenersatzmittel |
AUPQ228199A0 (en) | 1999-08-18 | 1999-09-09 | Sly, Anthony William | Ophthalmic fluid |
EP1251826B1 (de) * | 2000-01-20 | 2003-07-23 | Dr. GERHARD MANN chem.-pharm. Fabrik GmbH | Diclofenamid suspensionsgel |
DE10132876A1 (de) * | 2001-07-06 | 2003-01-30 | Medproject Pharma Entwicklungs | Zweiphasige, tropfbare Hydrogele zur Anwendung am Auge |
FR2835748B1 (fr) * | 2002-02-14 | 2007-06-15 | Veyron Et Froment Lab | Composition ophtalmique sous forme d'emulsion |
DE102005035986B4 (de) * | 2005-07-28 | 2009-10-15 | Bausch & Lomb Incorporated | Steriles tropfbares mehrphasiges emulgatorfreies ophthalmisches Präparat |
CN1883469B (zh) * | 2006-05-26 | 2011-07-20 | 武汉远大制药集团有限公司 | 一种含有维生素a和维生素e的眼用微乳及其制备方法 |
DE102006049091A1 (de) * | 2006-10-18 | 2008-04-24 | Dr. Gerhard Mann Chem.-Pharm. Fabrik Gmbh | Emulgatorfreies ophthalmisches Präparat enthaltend Pflanzenöl |
GB2445539A (en) * | 2006-12-29 | 2008-07-16 | Ardana Bioscience Ltd | Bigel composition |
CN101028240B (zh) * | 2007-03-29 | 2010-06-09 | 中国科学院上海药物研究所 | 眼用微乳/亚微乳原位凝胶制剂及其制备方法 |
FR2916636B1 (fr) | 2007-05-29 | 2009-09-04 | Octalia Technologies | Vehicule sous forme d'une emulsion huile-dans-eau notamment destine a une utilisation ophtalmique ou dermocosmetique |
US20120294898A1 (en) * | 2011-05-19 | 2012-11-22 | Warsaw Orthopedic, Inc. | Injectable dbm for soft tissue repair |
US10383839B2 (en) | 2011-06-30 | 2019-08-20 | Johnson & Johnson Vision Care, Inc. | Esters for treatment of ocular inflammatory conditions |
US11596599B2 (en) | 2012-05-03 | 2023-03-07 | The Johns Hopkins University | Compositions and methods for ophthalmic and/or other applications |
US9827191B2 (en) | 2012-05-03 | 2017-11-28 | The Johns Hopkins University | Compositions and methods for ophthalmic and/or other applications |
US10688041B2 (en) | 2012-05-03 | 2020-06-23 | Kala Pharmaceuticals, Inc. | Compositions and methods utilizing poly(vinyl alcohol) and/or other polymers that aid particle transport in mucus |
JP6360039B2 (ja) | 2012-05-03 | 2018-07-18 | カラ ファーマシューティカルズ インコーポレイテッド | 複数の被覆された粒子を含む組成物、医薬組成物、医薬製剤、及び当該粒子の形成方法 |
PL3231417T3 (pl) * | 2016-04-15 | 2019-05-31 | Dr Gerhard Mann Chem Pharm Fabrik Gmbh | Odporna na składowanie kompozycja oftalmiczna |
EP3412276A3 (de) * | 2017-06-09 | 2019-07-17 | Omnivision GmbH | Zusammensetzung zur behandlung des trockenen auges |
WO2019022182A1 (ja) * | 2017-07-26 | 2019-01-31 | 一般財団法人阪大微生物病研究会 | 無菌化された粘稠性基剤の製造方法及び医薬製剤の製造方法 |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3066859D1 (en) * | 1979-10-26 | 1984-04-12 | Smith & Nephew Ass | Autoclavable emulsions |
JPS57171912A (en) | 1981-04-14 | 1982-10-22 | Sumitomo Chem Co Ltd | Cream |
US4421748A (en) | 1982-07-13 | 1983-12-20 | Trager Seymour F | Artificial tear aid |
DE3440352A1 (de) * | 1984-11-05 | 1986-05-07 | Dr. Thilo & Co GmbH, 8029 Sauerlach | Dry-eye-packung |
JPS61130215A (ja) * | 1984-11-28 | 1986-06-18 | Santen Pharmaceut Co Ltd | フルオロメトロンの水溶化方法 |
JPS61249918A (ja) * | 1985-04-26 | 1986-11-07 | Yutaka Mizushima | 点眼剤 |
EP0316345A1 (en) | 1986-07-28 | 1989-05-24 | Liposome Technology, Inc. | Liposomes with enhanced retention on mucosal tissue |
US5032392A (en) * | 1986-09-04 | 1991-07-16 | Vision Pharmaceuticals | Aqueous ophthalmic solutions for the treatment of dryness and/or irritation of human or animal eyes |
US4966773A (en) * | 1986-11-25 | 1990-10-30 | Alcon Laboratories, Inc. | Topical ophthalmic compositions containing microfine retinoid particles |
US4914088A (en) | 1987-04-02 | 1990-04-03 | Thomas Glonek | Dry eye treatment solution and method |
US4866049A (en) | 1987-08-10 | 1989-09-12 | Spectra Pharmaceutical Services, Inc. | Ophthalmic compositionn and method of using same |
LU87416A1 (fr) * | 1988-12-29 | 1990-07-10 | Cird | Microgranules charges en une substance active,constitues essentiellement d'un triglyceride d'acides gras satures et leur utilisation par voie topique dans le domaine therapeutique |
AU614465B2 (en) | 1989-04-05 | 1991-08-29 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Medicinal emulsions |
EP0459148B1 (en) | 1990-05-29 | 1996-01-03 | Ocular Research Of Boston Inc. | Dry eye treatment composition |
US5252318A (en) * | 1990-06-15 | 1993-10-12 | Allergan, Inc. | Reversible gelation compositions and methods of use |
IL98747A0 (en) * | 1991-07-05 | 1992-07-15 | Yissum Res Dev Co | Ophthalmic compositions |
FR2679135B1 (fr) * | 1991-07-18 | 1995-05-19 | Europhta Sa Laboratoire | Nouvelles compositions ophtalmiques a adhesivite amelioree et leurs procedes de preparation. |
JP3072340B2 (ja) * | 1991-10-21 | 2000-07-31 | ポーラ化成工業株式会社 | 水性目薬及びその製造法 |
FR2690846B1 (fr) | 1992-05-05 | 1995-07-07 | Aiache Jean Marc | Forme galenique pour administration oculaire et procede de preparation. |
EP0656779B1 (en) | 1992-08-28 | 2000-04-12 | Pharmos Corporation | Submicron emulsions as ocular drug delivery vehicles |
WO1994014416A1 (en) * | 1992-12-29 | 1994-07-07 | Insite Vision Incorporated | Bioerodible controlled delivery system |
RU2108112C1 (ru) | 1993-04-16 | 1998-04-10 | Вакамото Фармасьютикал Ко., Лтд. | Водная лекарственная композиция, обладающая свойством обратимого терморегулируемого гелеобразования |
JP3438264B2 (ja) * | 1993-07-07 | 2003-08-18 | ライオン株式会社 | 安定なビタミンa類可溶化水性点眼剤の調製方法 |
US5744155A (en) * | 1993-08-13 | 1998-04-28 | Friedman; Doron | Bioadhesive emulsion preparations for enhanced drug delivery |
-
1995
- 1995-03-28 DE DE19511322A patent/DE19511322C2/de not_active Expired - Lifetime
-
1996
- 1996-02-20 AT AT96904826T patent/ATE201588T1/de active
- 1996-02-20 JP JP52883196A patent/JP3860609B2/ja not_active Expired - Lifetime
- 1996-02-20 ES ES96904826T patent/ES2159354T3/es not_active Expired - Lifetime
- 1996-02-20 EP EP96904826A patent/EP0817610B1/de not_active Expired - Lifetime
- 1996-02-20 NZ NZ328774A patent/NZ328774A/en not_active IP Right Cessation
- 1996-02-20 DE DE59607005T patent/DE59607005D1/de not_active Expired - Lifetime
- 1996-02-20 WO PCT/EP1996/000697 patent/WO1996029984A1/de active IP Right Grant
- 1996-02-20 PL PL96324620A patent/PL184695B1/pl unknown
- 1996-02-20 HU HU9801243A patent/HU222108B1/hu active IP Right Grant
- 1996-02-20 BR BR9604878-6A patent/BR9604878A/pt not_active IP Right Cessation
- 1996-02-20 CZ CZ19972952A patent/CZ291002B6/cs not_active IP Right Cessation
- 1996-02-20 PT PT96904826T patent/PT817610E/pt unknown
- 1996-02-20 SK SK1314-97A patent/SK281594B6/sk not_active IP Right Cessation
- 1996-02-20 CN CN96192797A patent/CN1090476C/zh not_active Expired - Lifetime
- 1996-02-20 US US08/930,239 patent/US6610318B1/en not_active Expired - Lifetime
- 1996-02-20 KR KR1019970706705A patent/KR100384059B1/ko not_active IP Right Cessation
- 1996-02-20 DK DK96904826T patent/DK0817610T3/da active
- 1996-02-20 SI SI9620048A patent/SI9620048A/sl unknown
-
1997
- 1997-09-26 FI FI973797A patent/FI119045B/fi not_active IP Right Cessation
- 1997-09-26 NO NO19974450A patent/NO316664B1/no not_active IP Right Cessation
-
1998
- 1998-10-31 HK HK98111687A patent/HK1010941A1/xx unknown
-
2001
- 2001-08-20 GR GR20010401269T patent/GR3036418T3/el unknown
-
2005
- 2005-08-12 JP JP2005233854A patent/JP4729364B2/ja not_active Expired - Lifetime
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HFG4 | Patent granted, date of granting |
Effective date: 20030220 |