EP2934751A4 - Filme mit geringere elastizität zur mikrofluidischen verwendung - Google Patents
Filme mit geringere elastizität zur mikrofluidischen verwendungInfo
- Publication number
- EP2934751A4 EP2934751A4 EP13865758.0A EP13865758A EP2934751A4 EP 2934751 A4 EP2934751 A4 EP 2934751A4 EP 13865758 A EP13865758 A EP 13865758A EP 2934751 A4 EP2934751 A4 EP 2934751A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- low elasticity
- microfluidic
- films
- elasticity films
- microfluidic use
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B19/00—Machines or pumps having pertinent characteristics not provided for in, or of interest apart from, groups F04B1/00 - F04B17/00
- F04B19/006—Micropumps
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B43/00—Machines, pumps, or pumping installations having flexible working members
- F04B43/02—Machines, pumps, or pumping installations having flexible working members having plate-like flexible members, e.g. diaphragms
- F04B43/04—Pumps having electric drive
- F04B43/043—Micropumps
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K99/00—Subject matter not provided for in other groups of this subclass
- F16K99/0001—Microvalves
- F16K99/0003—Constructional types of microvalves; Details of the cutting-off member
- F16K99/0015—Diaphragm or membrane valves
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K99/00—Subject matter not provided for in other groups of this subclass
- F16K99/0001—Microvalves
- F16K99/0034—Operating means specially adapted for microvalves
- F16K99/0055—Operating means specially adapted for microvalves actuated by fluids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K99/00—Subject matter not provided for in other groups of this subclass
- F16K2099/0082—Microvalves adapted for a particular use
- F16K2099/0084—Chemistry or biology, e.g. "lab-on-a-chip" technology
Landscapes
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Dispersion Chemistry (AREA)
- Mechanical Engineering (AREA)
- Analytical Chemistry (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Reciprocating Pumps (AREA)
- Micromachines (AREA)
- Details Of Reciprocating Pumps (AREA)
- Computer Hardware Design (AREA)
- Microelectronics & Electronic Packaging (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP19175141.1A EP3549674B1 (de) | 2012-12-21 | 2013-12-20 | Filme mit geringere elastizität zur mikrofluidischen verwendung |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261745340P | 2012-12-21 | 2012-12-21 | |
PCT/US2013/077269 WO2014100743A2 (en) | 2012-12-21 | 2013-12-20 | Low elasticity films for microfluidic use |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP19175141.1A Division EP3549674B1 (de) | 2012-12-21 | 2013-12-20 | Filme mit geringere elastizität zur mikrofluidischen verwendung |
Publications (3)
Publication Number | Publication Date |
---|---|
EP2934751A2 EP2934751A2 (de) | 2015-10-28 |
EP2934751A4 true EP2934751A4 (de) | 2016-11-16 |
EP2934751B1 EP2934751B1 (de) | 2019-05-29 |
Family
ID=50979415
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP19175141.1A Active EP3549674B1 (de) | 2012-12-21 | 2013-12-20 | Filme mit geringere elastizität zur mikrofluidischen verwendung |
EP13865758.0A Active EP2934751B1 (de) | 2012-12-21 | 2013-12-20 | Filme mit geringere elastizität zur mikrofluidischen verwendung |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP19175141.1A Active EP3549674B1 (de) | 2012-12-21 | 2013-12-20 | Filme mit geringere elastizität zur mikrofluidischen verwendung |
Country Status (6)
Country | Link |
---|---|
US (2) | US10518262B2 (de) |
EP (2) | EP3549674B1 (de) |
JP (3) | JP6935167B2 (de) |
KR (1) | KR20150096788A (de) |
CN (2) | CN107824233B (de) |
WO (1) | WO2014100743A2 (de) |
Families Citing this family (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR101851117B1 (ko) | 2010-01-29 | 2018-04-23 | 마이크로닉스 인코포레이티드. | 샘플-투-앤서 마이크로유체 카트리지 |
WO2014100725A1 (en) | 2012-12-21 | 2014-06-26 | Micronics, Inc. | Portable fluorescence detection system and microassay cartridge |
EP3549674B1 (de) | 2012-12-21 | 2020-08-12 | PerkinElmer Health Sciences, Inc. | Filme mit geringere elastizität zur mikrofluidischen verwendung |
US10065186B2 (en) | 2012-12-21 | 2018-09-04 | Micronics, Inc. | Fluidic circuits and related manufacturing methods |
USD758372S1 (en) * | 2013-03-13 | 2016-06-07 | Nagrastar Llc | Smart card interface |
US9888283B2 (en) | 2013-03-13 | 2018-02-06 | Nagrastar Llc | Systems and methods for performing transport I/O |
JP6472788B2 (ja) | 2013-05-07 | 2019-02-20 | マイクロニクス, インコーポレイテッド | 粘土鉱物およびアルカリ性溶液を使用して核酸含有試料を調製するための方法 |
EP2994750B1 (de) | 2013-05-07 | 2020-08-12 | PerkinElmer Health Sciences, Inc. | Mikrofluidische vorrichtungen und verfahren zur durchführung von serumtrennung und blutkreuzproben |
JP6484222B2 (ja) | 2013-05-07 | 2019-03-13 | マイクロニクス, インコーポレイテッド | 核酸の調製および分析のためのデバイス |
EP3594360B1 (de) | 2014-04-24 | 2021-06-23 | Lucira Health, Inc. | Kolorimetrische detektion von nukleinsäureamplifikation |
WO2015191916A1 (en) | 2014-06-11 | 2015-12-17 | Micronics, Inc. | Microfluidic cartridges and apparatus with integrated assay controls for analysis of nucleic acids |
USD864968S1 (en) | 2015-04-30 | 2019-10-29 | Echostar Technologies L.L.C. | Smart card interface |
US9901921B2 (en) * | 2015-05-28 | 2018-02-27 | David W. Wright | Disposable invitro diagnostic cartridge and method of performing an invitro diagnostic test |
DE102016200256A1 (de) * | 2016-01-13 | 2017-07-13 | Robert Bosch Gmbh | Pumpvorrichtung und Partikeldetektor mit einer Pumpvorrichtung |
WO2017149977A1 (ja) * | 2016-02-29 | 2017-09-08 | パナソニックIpマネジメント株式会社 | 非水電解質二次電池 |
AU2017232344B2 (en) * | 2016-03-14 | 2022-08-04 | Pfizer Inc. | Selectively vented biological assay devices and associated methods |
WO2017160839A1 (en) | 2016-03-14 | 2017-09-21 | Diassess Inc. | Devices and methods for modifying optical properties |
EP3429752A4 (de) | 2016-03-14 | 2019-10-30 | Lucira Health, Inc. | Systeme und verfahren zur durchführung von biologischen tests |
AU2017232342B2 (en) | 2016-03-14 | 2022-04-21 | Pfizer Inc. | Devices and methods for biological assay sample preparation and delivery |
EP3222351A1 (de) * | 2016-03-23 | 2017-09-27 | Ecole Polytechnique Federale de Lausanne (EPFL) | Mikrofluidische netzwerkvorrichtung |
US10478818B1 (en) * | 2016-03-24 | 2019-11-19 | National Technology & Engineering Solutions Of Sandia, Llc | Check valves for microfluidic systems and methods thereof |
JP6992042B2 (ja) * | 2016-07-04 | 2022-01-13 | フラウンホッファー-ゲゼルシャフト ツァ フェルダールング デァ アンゲヴァンテン フォアシュンク エー.ファオ | マイクロ流体アクチュエータを有する装置 |
WO2018065117A1 (en) | 2016-10-07 | 2018-04-12 | Boehringer Ingelheim Vetmedica Gmbh | Cartridge, analysis system and method for testing a sample |
US11080848B2 (en) | 2017-04-06 | 2021-08-03 | Lucira Health, Inc. | Image-based disease diagnostics using a mobile device |
US10549275B2 (en) | 2017-09-14 | 2020-02-04 | Lucira Health, Inc. | Multiplexed biological assay device with electronic readout |
KR102245674B1 (ko) | 2017-11-17 | 2021-04-27 | 주식회사 엘지화학 | 고상 추출용 마이크로 디바이스 |
DE102017128229A1 (de) * | 2017-11-29 | 2019-05-29 | Bürkert Werke GmbH & Co. KG | Membranbaugruppe für ein Membranventil sowie Membranventil |
CN108150672A (zh) * | 2017-12-08 | 2018-06-12 | 北京大学 | 截止阀 |
CN108372669A (zh) * | 2018-03-06 | 2018-08-07 | 南京道隆生物科技有限公司 | 一种卫生级隔膜片及其制造工艺 |
US10935149B2 (en) | 2018-03-15 | 2021-03-02 | University Of Washington | Temperature-actuated valve, fluidic device, and related methods of use |
WO2020033307A1 (en) * | 2018-08-06 | 2020-02-13 | Signal Biosystems Llc | Microfluidic devices and uses thereof |
WO2020072837A1 (en) * | 2018-10-03 | 2020-04-09 | Ostial Corporation | Inflation devices and systems for balloon catheters and methods for use |
CN109139434B (zh) * | 2018-10-25 | 2024-01-19 | 重庆水泵厂有限责任公司 | 隔膜泵隔膜非等位挠曲形变控制方法 |
NL2022085B1 (en) * | 2018-11-28 | 2020-06-25 | Mimetas B V | Device for assessing mechanical strain induced in or by cells |
USD910200S1 (en) | 2018-12-21 | 2021-02-09 | Lucira Health, Inc. | Test tube |
CN111379692A (zh) * | 2018-12-29 | 2020-07-07 | 宁波永基精密科技有限公司 | 隔膜泵和隔膜 |
JP2020138283A (ja) * | 2019-02-28 | 2020-09-03 | 株式会社エンプラス | 流体取扱装置の製造方法 |
CN110316691B (zh) * | 2019-06-20 | 2022-05-20 | 清华大学 | 微型气动/液压驱动器及其加工方法 |
CN110220836B (zh) * | 2019-06-26 | 2021-12-21 | 国科赛赋(深圳)新药研发科技有限公司 | 一种体外检测用流式细胞分析仪 |
FR3102558A1 (fr) * | 2019-10-29 | 2021-04-30 | bioMérieux | Système de dilution dans un dispositif et procédé de fabrication du dispositif |
CN111274648B (zh) * | 2019-12-24 | 2023-04-07 | 中国航空工业集团公司沈阳飞机设计研究所 | 一种民用飞机前缘襟翼的分布式飞行载荷设计方法 |
CN111043349B (zh) * | 2020-01-06 | 2021-10-22 | 浙江科力车辆控制系统有限公司 | 膜片式油泵呼吸阀 |
US20230083434A1 (en) * | 2020-02-12 | 2023-03-16 | University Of Canterbury | Microfluidic sealing valve and microfluidic circuit |
USD1001418S1 (en) * | 2020-02-12 | 2023-10-17 | Blue Force Gear, Inc. | Belt |
CN111440720A (zh) * | 2020-04-17 | 2020-07-24 | 海口健康岛生物科技有限公司 | 一种免疫细胞培养装置 |
GB2594331A (en) * | 2020-04-24 | 2021-10-27 | Martin Lauschke Volker | Device |
USD953561S1 (en) | 2020-05-05 | 2022-05-31 | Lucira Health, Inc. | Diagnostic device with LED display |
USD962470S1 (en) | 2020-06-03 | 2022-08-30 | Lucira Health, Inc. | Assay device with LCD display |
GB2599357A (en) * | 2020-09-21 | 2022-04-06 | Quantumdx Group Ltd | Microfluidic device with positive displacement pump |
CN112195099B (zh) * | 2020-10-21 | 2022-12-20 | 清华大学深圳国际研究生院 | 一种用于核酸检测的微流控芯片 |
CN112481123B (zh) * | 2020-11-16 | 2022-02-15 | 大连理工大学 | 一种研究剪切力和生化因子梯度调控细胞划痕修复的微流控系统及方法 |
CN112657562B (zh) * | 2020-12-11 | 2022-05-17 | 浙江省海洋水产研究所 | 一种实验室用多用途材料存放装置 |
CN114768894B (zh) * | 2021-01-22 | 2023-08-11 | 中国科学院上海微系统与信息技术研究所 | 一种检测芯片及检测方法 |
TWI757167B (zh) * | 2021-05-04 | 2022-03-01 | 國立清華大學 | 擾流穩定晶片、液滴生成系統及液滴製備方法 |
CN114534809B (zh) * | 2022-02-25 | 2023-12-01 | 河海大学常州校区 | 一种截面形状可调的微流控微粒操控器件及微粒操控方法 |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0399859A1 (de) * | 1989-05-22 | 1990-11-28 | Clextral | Vorrichtung zum Messen der Scherbelastung von in Extrudern behandelter Materie |
EP0517631A1 (de) * | 1991-06-07 | 1992-12-09 | Transfluid Sa | Ventil mit metallischer Membran |
US6007309A (en) * | 1995-12-13 | 1999-12-28 | Hartley; Frank T. | Micromachined peristaltic pumps |
WO2003101887A2 (en) * | 2002-06-03 | 2003-12-11 | Ing. Ilja Krejci - Engineering | Three-dimentional components prepared by thick film technology and method of producing thereof |
JP2006073371A (ja) * | 2004-09-02 | 2006-03-16 | Toray Ind Inc | 高分子電解質材、ならびにそれを用いた高分子電解質膜、膜電極複合体および高分子電解質型燃料電池 |
US20070234785A1 (en) * | 2006-03-30 | 2007-10-11 | Timothy Beerling | System and method for using a flexible membrane for controlling fluid flow in a microfluidic circuit |
Family Cites Families (359)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5622871A (en) | 1987-04-27 | 1997-04-22 | Unilever Patent Holdings B.V. | Capillary immunoassay and device therefor comprising mobilizable particulate labelled reagents |
US3013467A (en) | 1957-11-07 | 1961-12-19 | Minsky Marvin | Microscopy apparatus |
US3799742A (en) | 1971-12-20 | 1974-03-26 | C Coleman | Miniaturized integrated analytical test container |
US3996345A (en) | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
US4181650A (en) | 1975-08-25 | 1980-01-01 | Maier Charles L Jr | Procedure for the assay of pharmacologically immunologically and biochemically active compounds in biological fluids |
SE399768B (sv) | 1975-09-29 | 1978-02-27 | Lilja Jan E | Kyvett for provtagning, blandning av, provet med ett reagensmedel och direkt utforande av, serskilt optisk, analys av det med reagensmedlet blandade provet |
US4235960A (en) | 1977-07-29 | 1980-11-25 | The Medical College Of Wisconsin, Inc. | Competitive enzyme-linked immunoassay |
NL8000173A (nl) | 1980-01-11 | 1981-08-03 | Akzo Nv | Toepassing van in water dispergeerbare, hydrofobe kleurstoffen als label in immunochemische testen. |
US4304257A (en) | 1980-07-01 | 1981-12-08 | Instrumentation Laboratory Inc. | Valve with flexible sheet member |
US4366241A (en) | 1980-08-07 | 1982-12-28 | Syva Company | Concentrating zone method in heterogeneous immunoassays |
US4610678A (en) | 1983-06-24 | 1986-09-09 | Weisman Paul T | High-density absorbent structures |
JPS61137066A (ja) | 1984-12-07 | 1986-06-24 | Toshiba Corp | 自動化学分析装置の測光方式 |
EP0207935A1 (de) | 1984-12-07 | 1987-01-14 | LILLA, James A. | Armschlinge mit freitragendem stützglied |
US4883750A (en) | 1984-12-13 | 1989-11-28 | Applied Biosystems, Inc. | Detection of specific sequences in nucleic acids |
US5038852A (en) | 1986-02-25 | 1991-08-13 | Cetus Corporation | Apparatus and method for performing automated amplification of nucleic acid sequences and assays using heating and cooling steps |
US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
US4965188A (en) | 1986-08-22 | 1990-10-23 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme |
US4788729A (en) | 1985-04-14 | 1988-12-06 | Walker Robert A | Air mattress with audible pressure relief valve |
EP0221105A1 (de) | 1985-04-29 | 1987-05-13 | Hichem Diagnostics, Inc., Dba Bural Technologies | Diagnosetestsatz |
CA1291031C (en) | 1985-12-23 | 1991-10-22 | Nikolaas C.J. De Jaeger | Method for the detection of specific binding agents and their correspondingbindable substances |
US4800159A (en) | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
US5160701A (en) | 1986-02-18 | 1992-11-03 | Abbott Laboratories | Solid-phase analytical device and method for using same |
AU622104B2 (en) | 1987-03-11 | 1992-04-02 | Sangtec Molecular Diagnostics Ab | Method of assaying of nucleic acids, a reagent combination and kit therefore |
CA1303983C (en) | 1987-03-27 | 1992-06-23 | Robert W. Rosenstein | Solid phase assay |
US4810630A (en) | 1987-03-30 | 1989-03-07 | E. I. Du Pont De Nemours And Company | Use of polyoxyethylene ethers to improve the performance of immunoassays employing peroxidase conjugates |
US4849340A (en) | 1987-04-03 | 1989-07-18 | Cardiovascular Diagnostics, Inc. | Reaction system element and method for performing prothrombin time assay |
ATE195022T1 (de) | 1987-04-27 | 2000-08-15 | Unilever Nv | Spezifische bindungstestverfahren |
US4855240A (en) | 1987-05-13 | 1989-08-08 | Becton Dickinson And Company | Solid phase assay employing capillary flow |
US4943522A (en) | 1987-06-01 | 1990-07-24 | Quidel | Lateral flow, non-bibulous membrane assay protocols |
US4833332A (en) | 1987-06-12 | 1989-05-23 | E. I. Du Pont De Nemours And Company | Scanning fluorescent detection system |
IL86724A (en) | 1987-06-19 | 1995-01-24 | Siska Diagnostics Inc | Methods and kits for amplification and testing of nucleic acid sequences |
US5120643A (en) | 1987-07-13 | 1992-06-09 | Abbott Laboratories | Process for immunochromatography with colloidal particles |
US4956302A (en) | 1987-09-11 | 1990-09-11 | Abbott Laboratories | Lateral flow chromatographic binding assay device |
US5275785A (en) | 1987-10-30 | 1994-01-04 | Unilever Patent Holdings B.V. | Test device for detecting an analyte in a liquid sample |
CA1323293C (en) | 1987-12-11 | 1993-10-19 | Keith C. Backman | Assay using template-dependent nucleic acid probe reorganization |
US4848722A (en) | 1987-12-11 | 1989-07-18 | Integrated Fluidics, Inc. | Valve with flexible sheet member |
EP0359789B1 (de) | 1988-01-21 | 1993-08-04 | Genentech, Inc. | Verstärkung und nachweis von nukleinsäuresequenzen |
US5670381A (en) | 1988-01-29 | 1997-09-23 | Abbott Laboratories | Devices for performing ion-capture binding assays |
CA1340807C (en) | 1988-02-24 | 1999-11-02 | Lawrence T. Malek | Nucleic acid amplification process |
AU623642B2 (en) | 1988-03-24 | 1992-05-21 | University Of Iowa Research Foundation, The | Catalytic hybridization systems for the detection of nucleic acid sequences based on their activity as cofactors in catalytic reactions in which a complementary labeled nucleic acid probe is cleaved |
US5130238A (en) | 1988-06-24 | 1992-07-14 | Cangene Corporation | Enhanced nucleic acid amplification process |
US5252459A (en) | 1988-09-23 | 1993-10-12 | Abbott Laboratories | Indicator reagents, diagnostic assays and test kits employing organic polymer latex particles |
CA1339731C (en) | 1988-10-12 | 1998-03-17 | Charles T. Caskey | Multiplex genomic dna amplification for deletion detection |
US4869282A (en) | 1988-12-09 | 1989-09-26 | Rosemount Inc. | Micromachined valve with polyimide film diaphragm |
US5234809A (en) | 1989-03-23 | 1993-08-10 | Akzo N.V. | Process for isolating nucleic acid |
US5225163A (en) | 1989-08-18 | 1993-07-06 | Angenics, Inc. | Reaction apparatus employing gravitational flow |
JP2520468Y2 (ja) | 1989-08-23 | 1996-12-18 | テイケイ気化器株式会社 | ダイヤフラムポンプ |
US4946527A (en) * | 1989-09-19 | 1990-08-07 | The Procter & Gamble Company | Pressure-sensitive adhesive fastener and method of making same |
US5075078A (en) | 1989-10-05 | 1991-12-24 | Abbott Laboratories | Self-performing immunochromatographic device |
US5427930A (en) | 1990-01-26 | 1995-06-27 | Abbott Laboratories | Amplification of target nucleic acids using gap filling ligase chain reaction |
US5141850A (en) | 1990-02-07 | 1992-08-25 | Hygeia Sciences, Inc. | Porous strip form assay device method |
US5096837A (en) | 1990-02-08 | 1992-03-17 | Pacific Biotech, Inc. | Immunochromatographic assay and method of using same |
US5100626A (en) | 1990-05-24 | 1992-03-31 | Levin Andrew E | Binding assay device with removable cassette and manifold |
US6787338B2 (en) | 1990-06-04 | 2004-09-07 | The University Of Utah | Method for rapid thermal cycling of biological samples |
GB9014263D0 (en) | 1990-06-27 | 1990-08-15 | Dixon Arthur E | Apparatus and method for spatially- and spectrally- resolvedmeasurements |
DE69229334T2 (de) | 1991-01-11 | 1999-12-16 | Quidel Corp | Einstufiges querfluss analysenverfahren und ein darin verwendeter nichtsaugfähiger träger |
US5455166A (en) | 1991-01-31 | 1995-10-03 | Becton, Dickinson And Company | Strand displacement amplification |
US5270183A (en) | 1991-02-08 | 1993-12-14 | Beckman Research Institute Of The City Of Hope | Device and method for the automated cycling of solutions between two or more temperatures |
SE9100392D0 (sv) | 1991-02-08 | 1991-02-08 | Pharmacia Biosensor Ab | A method of producing a sealing means in a microfluidic structure and a microfluidic structure comprising such sealing means |
US5314804A (en) | 1992-03-24 | 1994-05-24 | Serim Research Corporation | Test for Helicobacter pylori |
US5296703A (en) | 1992-04-01 | 1994-03-22 | The Regents Of The University Of California | Scanning confocal microscope using fluorescence detection |
US5304487A (en) | 1992-05-01 | 1994-04-19 | Trustees Of The University Of Pennsylvania | Fluid handling in mesoscale analytical devices |
US5486335A (en) | 1992-05-01 | 1996-01-23 | Trustees Of The University Of Pennsylvania | Analysis based on flow restriction |
US6953676B1 (en) | 1992-05-01 | 2005-10-11 | Trustees Of The University Of Pennsylvania | Mesoscale polynucleotide amplification device and method |
US5498392A (en) | 1992-05-01 | 1996-03-12 | Trustees Of The University Of Pennsylvania | Mesoscale polynucleotide amplification device and method |
US5726026A (en) | 1992-05-01 | 1998-03-10 | Trustees Of The University Of Pennsylvania | Mesoscale sample preparation device and systems for determination and processing of analytes |
US5587128A (en) | 1992-05-01 | 1996-12-24 | The Trustees Of The University Of Pennsylvania | Mesoscale polynucleotide amplification devices |
US6905882B2 (en) | 1992-05-21 | 2005-06-14 | Biosite, Inc. | Diagnostic devices and apparatus for the controlled movement of reagents without membranes |
WO1994003624A1 (en) | 1992-08-04 | 1994-02-17 | Auerbach Jeffrey I | Methods for the isothermal amplification of nucleic acid molecules |
US6472161B1 (en) | 1992-10-15 | 2002-10-29 | Robert F. Baugh | Method of evaluating blood clot lysis condition |
JP3563140B2 (ja) | 1995-01-19 | 2004-09-08 | 株式会社日立製作所 | キャピラリーアレイ電気泳動装置 |
US5730850A (en) | 1993-04-23 | 1998-03-24 | Hitachi, Ltd. | Capillary array electrophoresis system |
US5415994A (en) | 1993-08-02 | 1995-05-16 | Quidel Corporation | Lateral flow medical diagnostic assay device with sample extraction means |
US5635602A (en) | 1993-08-13 | 1997-06-03 | The Regents Of The University Of California | Design and synthesis of bispecific DNA-antibody conjugates |
DE4332720C2 (de) | 1993-09-25 | 1997-02-13 | Karlsruhe Forschzent | Mikromembranpumpe |
US5447440A (en) | 1993-10-28 | 1995-09-05 | I-Stat Corporation | Apparatus for assaying viscosity changes in fluid samples and method of conducting same |
US6309601B1 (en) | 1993-11-01 | 2001-10-30 | Nanogen, Inc. | Scanning optical detection system |
DK0653639T3 (da) | 1993-11-12 | 2000-07-24 | Unilever Nv | Analyseindretninger og fremgangsmåder til anvendelse deraf |
JPH07151101A (ja) | 1993-11-29 | 1995-06-13 | Kazuo Sugimura | ダイヤフラム接触面が渦巻状の容器 |
CH689836A5 (fr) | 1994-01-14 | 1999-12-15 | Westonbridge Int Ltd | Micropompe. |
US5543026A (en) | 1994-02-07 | 1996-08-06 | The Perkin-Elmer Corporation | Real-time scanning fluorescence electrophoresis apparatus for the analysis of polynucleotide fragments |
US5631734A (en) | 1994-02-10 | 1997-05-20 | Affymetrix, Inc. | Method and apparatus for detection of fluorescently labeled materials |
US6287850B1 (en) | 1995-06-07 | 2001-09-11 | Affymetrix, Inc. | Bioarray chip reaction apparatus and its manufacture |
US5639428A (en) | 1994-07-19 | 1997-06-17 | Becton Dickinson And Company | Method and apparatus for fully automated nucleic acid amplification, nucleic acid assay and immunoassay |
US5593824A (en) | 1994-09-02 | 1997-01-14 | Pharmacia Biotech, Inc. | Biological reagent spheres |
GB9419267D0 (en) | 1994-09-23 | 1994-11-09 | Unilever Plc | Assay devices |
DE4435107C1 (de) | 1994-09-30 | 1996-04-04 | Biometra Biomedizinische Analy | Miniaturisierter Fluß-Thermocycler |
US5707807A (en) | 1995-03-28 | 1998-01-13 | Research Development Corporation Of Japan | Molecular indexing for expressed gene analysis |
US5712172A (en) | 1995-05-18 | 1998-01-27 | Wyntek Diagnostics, Inc. | One step immunochromatographic device and method of use |
SE504193C2 (sv) | 1995-04-21 | 1996-12-02 | Hemocue Ab | Kapillär mikrokyvett |
US5578818A (en) | 1995-05-10 | 1996-11-26 | Molecular Dynamics | LED point scanning system |
DE69619400T2 (de) | 1995-06-16 | 2002-09-26 | Univ Washington Seattle | Flacher mikrogefertigter querstromfilter für flüssigkeiten |
DE69628016T2 (de) | 1995-06-16 | 2004-04-01 | University Of Washington, Seattle | Miniaturisierte differentielle extraktionsvorrichtung und verfahren |
US5716852A (en) | 1996-03-29 | 1998-02-10 | University Of Washington | Microfabricated diffusion-based chemical sensor |
SE9502258D0 (sv) | 1995-06-21 | 1995-06-21 | Pharmacia Biotech Ab | Method for the manufacture of a membrane-containing microstructure |
US6168948B1 (en) | 1995-06-29 | 2001-01-02 | Affymetrix, Inc. | Miniaturized genetic analysis systems and methods |
US5856174A (en) | 1995-06-29 | 1999-01-05 | Affymetrix, Inc. | Integrated nucleic acid diagnostic device |
US5724404A (en) | 1995-07-03 | 1998-03-03 | Garcia; Max | Integrated international telephone circuit monitoring system |
US5989813A (en) | 1995-07-13 | 1999-11-23 | Molecular Innovations, Inc. | Detection of amplified nucleic acid sequences using bifunctional haptenization and dyed microparticles |
US5660990A (en) | 1995-08-18 | 1997-08-26 | Immunivest Corporation | Surface immobilization of magnetically collected materials |
US5726751A (en) | 1995-09-27 | 1998-03-10 | University Of Washington | Silicon microchannel optical flow cytometer |
US5863502A (en) | 1996-01-24 | 1999-01-26 | Sarnoff Corporation | Parallel reaction cassette and associated devices |
US5741647A (en) | 1996-02-16 | 1998-04-21 | Tam; Joseph Wing On | Flow through nucleic acid hybridisation uses thereof and a device thereof |
US5660370A (en) | 1996-03-07 | 1997-08-26 | Integrated Fludics, Inc. | Valve with flexible sheet member and two port non-flexing backer member |
US5972721A (en) | 1996-03-14 | 1999-10-26 | The United States Of America As Represented By The Secretary Of The Air Force | Immunomagnetic assay system for clinical diagnosis and other purposes |
US5747349A (en) | 1996-03-20 | 1998-05-05 | University Of Washington | Fluorescent reporter beads for fluid analysis |
US6541213B1 (en) | 1996-03-29 | 2003-04-01 | University Of Washington | Microscale diffusion immunoassay |
US5948684A (en) | 1997-03-31 | 1999-09-07 | University Of Washington | Simultaneous analyte determination and reference balancing in reference T-sensor devices |
US6825047B1 (en) | 1996-04-03 | 2004-11-30 | Applera Corporation | Device and method for multiple analyte detection |
US6001307A (en) | 1996-04-26 | 1999-12-14 | Kyoto Daiichi Kagaku Co., Ltd. | Device for analyzing a sample |
US6057167A (en) | 1996-05-31 | 2000-05-02 | Motorola, Inc. | Magnetoresistance-based method and apparatus for molecular detection |
US5726404A (en) | 1996-05-31 | 1998-03-10 | University Of Washington | Valveless liquid microswitch |
WO1997047390A1 (en) | 1996-06-14 | 1997-12-18 | University Of Washington | Absorption-enhanced differential extraction device |
US5863801A (en) | 1996-06-14 | 1999-01-26 | Sarnoff Corporation | Automated nucleic acid isolation |
US6582921B2 (en) | 1996-07-29 | 2003-06-24 | Nanosphere, Inc. | Nanoparticles having oligonucleotides attached thereto and uses thereof |
EP0918563A1 (de) * | 1996-08-12 | 1999-06-02 | Hampshire Advisory and Technical Services Limited | Diagnostische testbehälter |
JPH1082773A (ja) | 1996-09-10 | 1998-03-31 | Kdk Corp | クロマトグラフィ装置における溶離液の供給方法、および溶離液収容体 |
US5798273A (en) | 1996-09-25 | 1998-08-25 | Becton Dickinson And Company | Direct read lateral flow assay for small analytes |
US5748827A (en) | 1996-10-23 | 1998-05-05 | University Of Washington | Two-stage kinematic mount |
US5971355A (en) | 1996-11-27 | 1999-10-26 | Xerox Corporation | Microdevice valve structures to fluid control |
JP3372436B2 (ja) | 1996-11-28 | 2003-02-04 | オークマ株式会社 | インバータの制御装置 |
US7052594B2 (en) | 2002-01-31 | 2006-05-30 | Sri International | Devices and methods for controlling fluid flow using elastic sheet deflection |
US5906602A (en) | 1997-03-27 | 1999-05-25 | The Procter & Gamble Company | Shaped absorbent cores comprising multiple pieces of absorbent material and method for making same |
JP4171075B2 (ja) | 1997-04-25 | 2008-10-22 | カリパー・ライフ・サイエンシズ・インコーポレーテッド | 改良されたチャネル幾何学的形状を組み込む微小流体装置 |
US5974867A (en) | 1997-06-13 | 1999-11-02 | University Of Washington | Method for determining concentration of a laminar sample stream |
WO1999000655A2 (en) | 1997-06-27 | 1999-01-07 | Immunetics, Inc. | Rapid flow-through binding assay apparatus and method |
US20050037397A1 (en) | 2001-03-28 | 2005-02-17 | Nanosphere, Inc. | Bio-barcode based detection of target analytes |
US6974669B2 (en) | 2000-03-28 | 2005-12-13 | Nanosphere, Inc. | Bio-barcodes based on oligonucleotide-modified nanoparticles |
US5932799A (en) | 1997-07-21 | 1999-08-03 | Ysi Incorporated | Microfluidic analyzer module |
WO1999009321A1 (fr) | 1997-08-20 | 1999-02-25 | Westonbridge International Limited | Micropompe comprenant un organe de controle d'entree permettant son auto-amorcage |
JP3498201B2 (ja) | 1997-08-27 | 2004-02-16 | アークレイ株式会社 | 引圧発生装置およびそれを用いた検体分析装置 |
US5965410A (en) | 1997-09-02 | 1999-10-12 | Caliper Technologies Corp. | Electrical current for controlling fluid parameters in microchannels |
US6007775A (en) | 1997-09-26 | 1999-12-28 | University Of Washington | Multiple analyte diffusion based chemical sensor |
US6953675B2 (en) | 1997-11-06 | 2005-10-11 | Immunomedics, Inc. | Landscaped antibodies and antibody fragments for clinical use |
US6037168A (en) | 1997-12-31 | 2000-03-14 | Cytonix Corporation | Microbiological assembly comprising resealable closure means |
SE9800070D0 (sv) | 1998-01-14 | 1998-01-14 | Hemocue Ab | Blandningsmetod |
US6210882B1 (en) | 1998-01-29 | 2001-04-03 | Mayo Foundation For Medical Education And Reseach | Rapid thermocycling for sample analysis |
US6210514B1 (en) | 1998-02-11 | 2001-04-03 | Xerox Corporation | Thin film structure machining and attachment |
US6018616A (en) | 1998-02-23 | 2000-01-25 | Applied Materials, Inc. | Thermal cycling module and process using radiant heat |
AU3771599A (en) | 1998-05-18 | 1999-12-06 | University Of Washington | Liquid analysis cartridge |
US6637463B1 (en) | 1998-10-13 | 2003-10-28 | Biomicro Systems, Inc. | Multi-channel microfluidic system design with balanced fluid flow distribution |
US6158712A (en) | 1998-10-16 | 2000-12-12 | Agilent Technologies, Inc. | Multilayer integrated assembly having an integral microminiature valve |
US6086740A (en) | 1998-10-29 | 2000-07-11 | Caliper Technologies Corp. | Multiplexed microfluidic devices and systems |
WO2000050642A1 (en) | 1999-02-23 | 2000-08-31 | Caliper Technologies Corp. | Sequencing by incorporation |
US6171850B1 (en) | 1999-03-08 | 2001-01-09 | Caliper Technologies Corp. | Integrated devices and systems for performing temperature controlled reactions and analyses |
US6673620B1 (en) | 1999-04-20 | 2004-01-06 | Cytologix Corporation | Fluid exchange in a chamber on a microscope slide |
WO2000063670A1 (en) | 1999-04-20 | 2000-10-26 | Cytologix Corporation | Fluid exchange in a chamber on a microscope slide |
JP4085514B2 (ja) | 1999-04-30 | 2008-05-14 | 株式会社島津製作所 | 電気泳動チップ |
US6399952B1 (en) | 1999-05-12 | 2002-06-04 | Aclara Biosciences, Inc. | Multiplexed fluorescent detection in microfluidic devices |
CA2374423C (en) | 1999-05-28 | 2013-04-09 | Cepheid | Apparatus and method for analyzing a liquid sample |
US6878540B2 (en) | 1999-06-25 | 2005-04-12 | Cepheid | Device for lysing cells, spores, or microorganisms |
DK1065378T3 (da) | 1999-06-28 | 2002-07-29 | California Inst Of Techn | Elastomere mikropumpe- og mikroventilsystemer |
US6899137B2 (en) | 1999-06-28 | 2005-05-31 | California Institute Of Technology | Microfabricated elastomeric valve and pump systems |
US6815160B1 (en) | 1999-07-28 | 2004-11-09 | Chiron Corporation | Hepatitis C viral antigen immunoassay detection systems |
US6731781B1 (en) | 1999-09-30 | 2004-05-04 | Biodiscovery, Inc. | System and method for automatically processing microarrays |
US6743399B1 (en) | 1999-10-08 | 2004-06-01 | Micronics, Inc. | Pumpless microfluidics |
US6272939B1 (en) | 1999-10-15 | 2001-08-14 | Applera Corporation | System and method for filling a substrate with a liquid sample |
US6569674B1 (en) | 1999-12-15 | 2003-05-27 | Amersham Biosciences Ab | Method and apparatus for performing biological reactions on a substrate surface |
ATE381328T1 (de) | 2000-02-02 | 2008-01-15 | Univ Florida State Res Found | Heterosubstituierte taxan-c10-acetate als antitumormittel |
US20040121364A1 (en) | 2000-02-07 | 2004-06-24 | Mark Chee | Multiplex nucleic acid reactions |
US6309875B1 (en) | 2000-02-29 | 2001-10-30 | Agilent Technologies, Inc. | Apparatus for biomolecular array hybridization facilitated by agitation during centrifuging |
DE60141454D1 (de) | 2000-03-14 | 2010-04-15 | Micronics Inc | Mikrofluid-analysekassette |
WO2001070381A2 (en) | 2000-03-21 | 2001-09-27 | Covaris, Inc. | Method and apparatus for acoustically controlling liquid solutions in microfluidic devices |
DE10013949A1 (de) | 2000-03-21 | 2001-09-27 | Mhb Filtration Gmbh & Co Kg | Adsorptives Filtermaterial |
US6635487B1 (en) | 2000-05-17 | 2003-10-21 | Caliper Technologies Corp. | Fluorescence standard for use in microfluidic instruments |
CA2409309A1 (en) | 2000-05-19 | 2001-11-29 | Eragen Biosciences, Inc. | Materials and methods for detection of nucleic acids |
WO2001089696A2 (en) | 2000-05-24 | 2001-11-29 | Micronics, Inc. | Microfluidic concentration gradient loop |
US6431212B1 (en) | 2000-05-24 | 2002-08-13 | Jon W. Hayenga | Valve for use in microfluidic structures |
US6568286B1 (en) * | 2000-06-02 | 2003-05-27 | Honeywell International Inc. | 3D array of integrated cells for the sampling and detection of air bound chemical and biological species |
US7351376B1 (en) | 2000-06-05 | 2008-04-01 | California Institute Of Technology | Integrated active flux microfluidic devices and methods |
US7087414B2 (en) | 2000-06-06 | 2006-08-08 | Applera Corporation | Methods and devices for multiplexing amplification reactions |
US6439036B1 (en) | 2000-06-13 | 2002-08-27 | Symyx Technologics, Inc. | Method for evaluating a test fluid |
US6581899B2 (en) | 2000-06-23 | 2003-06-24 | Micronics, Inc. | Valve for use in microfluidic structures |
AU2000274922A1 (en) | 2000-08-08 | 2002-02-18 | Aviva Biosciences Corporation | Methods for manipulating moieties in microfluidic systems |
EP1317569B1 (de) | 2000-09-14 | 2009-11-18 | Caliper Life Sciences, Inc. | MIKROFLUIDISCHE VORRICHTUNGEN UND METHODEN UM TEMPERATUR-VERMITTELTE REAKTIONEN DURCHZUFüHREN |
WO2002029106A2 (en) * | 2000-10-03 | 2002-04-11 | California Institute Of Technology | Microfluidic devices and methods of use |
CA2423630C (en) | 2000-10-03 | 2011-12-06 | Minerva Biotechnologies Corporation | Magnetic in situ dilution |
EP1337826A2 (de) | 2000-10-25 | 2003-08-27 | Exiqon A/S | Plattform als substrat zur analyse von biomoekuelen |
FR2816074B1 (fr) | 2000-10-30 | 2003-01-03 | St Microelectronics Sa | Generateur digital precis produisant des signaux d'horloge |
WO2002060582A2 (en) | 2000-11-16 | 2002-08-08 | Fluidigm Corporation | Microfluidic devices for introducing and dispensing fluids from microfluidic systems |
GB0028647D0 (en) | 2000-11-24 | 2001-01-10 | Nextgen Sciences Ltd | Apparatus for chemical assays |
JP2002190257A (ja) | 2000-12-22 | 2002-07-05 | Sanyo Electric Co Ltd | マグネトロンの製法 |
ES2232407T3 (es) | 2000-12-28 | 2005-06-01 | F. Hoffmann-La Roche Ag | Metodo para el procesado de una muestra de acido nucleico mediante la oscilacion de un segmento de una pared de un cartucho, un sistema y un cartucho para realizar dicho metodo. |
CA2431237A1 (en) | 2001-01-08 | 2002-07-11 | President And Fellows Of Harvard College | Valves and pumps for microfluidic systems and method for making microfluidic systems |
US7242665B2 (en) * | 2001-01-25 | 2007-07-10 | Ericsson Ab | Network device virtual interface |
CA2450676C (en) | 2001-03-09 | 2010-03-30 | Biomicro Systems, Inc. | Method and system for microfluidic interfacing to arrays |
DE10111457B4 (de) | 2001-03-09 | 2006-12-14 | Siemens Ag | Diagnoseeinrichtung |
WO2003015923A1 (en) | 2001-08-20 | 2003-02-27 | Biomicro Systems, Inc. | Fluid mixing in low aspect ratio chambers |
US6576459B2 (en) | 2001-03-23 | 2003-06-10 | The Regents Of The University Of California | Sample preparation and detection device for infectious agents |
US7010391B2 (en) | 2001-03-28 | 2006-03-07 | Handylab, Inc. | Methods and systems for control of microfluidic devices |
US20020159920A1 (en) | 2001-04-03 | 2002-10-31 | Weigl Bernhard H. | Multiple redundant microfluidic structures cross reference to related applications |
EP1384022A4 (de) | 2001-04-06 | 2004-08-04 | California Inst Of Techn | Nukleinsäure-amplifikation verwendende mikrofluidvorrichtungen |
US6802342B2 (en) | 2001-04-06 | 2004-10-12 | Fluidigm Corporation | Microfabricated fluidic circuit elements and applications |
US6562209B1 (en) | 2001-04-19 | 2003-05-13 | Northrop Grumman Corporation | Automated computer controlled reporter device for conducting imunnoassay and molecular biology procedures |
US6418968B1 (en) | 2001-04-20 | 2002-07-16 | Nanostream, Inc. | Porous microfluidic valves |
EP1260265B1 (de) | 2001-05-25 | 2005-02-02 | Tecan Trading AG | System mit Verfahrenseinheit zum Hybridisieren von Nukleinsäureproben, Proteinen und Gewebeschnitten |
US6729352B2 (en) | 2001-06-07 | 2004-05-04 | Nanostream, Inc. | Microfluidic synthesis devices and methods |
US20030032028A1 (en) | 2001-06-12 | 2003-02-13 | Gayle Dace | In vitro capture of nucleic acids via modified oligonucleotides and magnetic beads |
US20020192676A1 (en) | 2001-06-18 | 2002-12-19 | Madonna Angelo J. | Method for determining if a type of bacteria is present in a mixture |
US7141416B2 (en) | 2001-07-12 | 2006-11-28 | Burstein Technologies, Inc. | Multi-purpose optical analysis optical bio-disc for conducting assays and various reporting agents for use therewith |
US20040226348A1 (en) | 2001-07-24 | 2004-11-18 | Phillip Bruce | Magnetic assisted detection of magnetic beads using optical disc drives |
KR20040037143A (ko) | 2001-09-27 | 2004-05-04 | 로베르트 보쉬 게엠베하 | 액추에이터 |
GB0124341D0 (en) | 2001-10-10 | 2001-11-28 | Randox Lab Ltd | Assay |
US7344894B2 (en) | 2001-10-16 | 2008-03-18 | Agilent Technologies, Inc. | Thermal regulation of fluidic samples within a diagnostic cartridge |
US6554591B1 (en) | 2001-11-26 | 2003-04-29 | Motorola, Inc. | Micropump including ball check valve utilizing ceramic technology and method of fabrication |
JP2003166910A (ja) | 2001-11-30 | 2003-06-13 | Asahi Kasei Corp | 送液機構及び該送液機構を備える分析装置 |
US7691333B2 (en) | 2001-11-30 | 2010-04-06 | Fluidigm Corporation | Microfluidic device and methods of using same |
GB0129816D0 (en) | 2001-12-13 | 2002-01-30 | The Technology Partnership Plc | Testing device for chemical or biochemical analysis |
KR20040068968A (ko) | 2001-12-21 | 2004-08-02 | 코닌클리케 필립스 일렉트로닉스 엔.브이. | 마이크로-어레이상의 자기 나노입자들의 면적 밀도를측정하는 센서 및 방법 |
US6748975B2 (en) | 2001-12-26 | 2004-06-15 | Micralyne Inc. | Microfluidic valve and method of manufacturing same |
US6773677B2 (en) | 2002-01-09 | 2004-08-10 | Caliper Life Sciences, Inc. | Slide cassette for fluidic injection |
JP2003207454A (ja) | 2002-01-15 | 2003-07-25 | Minolta Co Ltd | 透過光検出装置 |
US7212526B2 (en) * | 2002-01-18 | 2007-05-01 | Hitachi, Ltd. | Method and apparatus for composing virtual links in a label switched network |
US7223371B2 (en) | 2002-03-14 | 2007-05-29 | Micronics, Inc. | Microfluidic channel network device |
US6955738B2 (en) | 2002-04-09 | 2005-10-18 | Gyros Ab | Microfluidic devices with new inner surfaces |
AUPS159702A0 (en) | 2002-04-09 | 2002-05-16 | Tong, Sun Wing | Molecular detection and assay by magneto-thermal biochip micro-assay |
US7785776B2 (en) | 2002-05-13 | 2010-08-31 | Idaho Technology, Inc. | Genotyping by amplicon melting curve analysis |
EP1527172B1 (de) | 2002-05-17 | 2008-11-26 | Molzym GmbH & Co. KG | Methode für die extraktion und aufreinigung von nukleinsäuren |
EP1509261B1 (de) | 2002-05-24 | 2007-12-12 | Baxter International Inc. | Dialysesystem mit anzeige, web browser und web server |
US20040033627A1 (en) | 2002-05-31 | 2004-02-19 | The Regents Of The University Of California | Method and apparatus for detecting substances of interest |
JP4106977B2 (ja) | 2002-06-21 | 2008-06-25 | 株式会社日立製作所 | 分析チップ及び分析装置 |
US6843263B2 (en) | 2002-06-24 | 2005-01-18 | Industrial Technology Research Institute | Partially closed microfluidic system and microfluidic driving method |
US7442342B2 (en) | 2002-06-26 | 2008-10-28 | Ge Healthcare Bio-Sciences Ab | Biochip holder and method of collecting fluid |
JP2004037485A (ja) | 2002-06-28 | 2004-02-05 | Mitsubishi Electric Corp | 半導体光変調器と半導体光装置 |
JP2004037338A (ja) | 2002-07-05 | 2004-02-05 | Yokogawa Electric Corp | 磁気ビーズを用いて生体高分子を基板へ固定する方法およびその方法を用いた生体高分子測定装置 |
US20040018611A1 (en) | 2002-07-23 | 2004-01-29 | Ward Michael Dennis | Microfluidic devices for high gradient magnetic separation |
US6817373B2 (en) | 2002-07-26 | 2004-11-16 | Applera Corporation | One-directional microball valve for a microfluidic device |
US7244961B2 (en) | 2002-08-02 | 2007-07-17 | Silicon Valley Scientific | Integrated system with modular microfluidic components |
US20040226620A1 (en) | 2002-09-26 | 2004-11-18 | Daniel Therriault | Microcapillary networks |
WO2004043991A2 (en) | 2002-11-13 | 2004-05-27 | Haematologic Technologies, Inc. | Assay for tissue factor and factor viia |
WO2004055199A2 (en) | 2002-12-12 | 2004-07-01 | Chiron Corporation | A biological sample storage device and method for biological sample contamination testing |
US8676383B2 (en) | 2002-12-23 | 2014-03-18 | Applied Biosystems, Llc | Device for carrying out chemical or biological reactions |
JP4764010B2 (ja) | 2002-12-26 | 2011-08-31 | メソ スケイル テクノロジーズ,エルエルシー | アッセイカートリッジ及び同アッセイカートリッジを用いた方法 |
US20060073484A1 (en) | 2002-12-30 | 2006-04-06 | Mathies Richard A | Methods and apparatus for pathogen detection and analysis |
US6807892B2 (en) | 2002-12-30 | 2004-10-26 | Xerox Corporation | Pneumatic actuator with elastomeric membrane and low-power electrostatic flap valve arrangement |
US20050221281A1 (en) | 2003-01-08 | 2005-10-06 | Ho Winston Z | Self-contained microfluidic biochip and apparatus |
CA2513424A1 (en) | 2003-01-14 | 2004-08-05 | Micronics Inc. | Microfluidic devices for fluid manipulation and analysis |
US7419638B2 (en) | 2003-01-14 | 2008-09-02 | Micronics, Inc. | Microfluidic devices for fluid manipulation and analysis |
EP1590482B1 (de) | 2003-01-17 | 2008-12-10 | Eragen Biosciences, Inc. | Nukleinsäureamplifikation mit nichtstandardbasen |
JP2006520190A (ja) | 2003-01-21 | 2006-09-07 | マイクロニクス, インコーポレイテッド | 流体の微小流体的な操作、増幅、および分析(例えば、細菌アッセイおよびアンチグロブリン試験)のための方法およびシステム |
US20070125947A1 (en) | 2003-02-20 | 2007-06-07 | David Sprinzak | Sample enclosure for a scanning electron microscope and methods of use thereof |
AU2003209572A1 (en) | 2003-03-08 | 2004-09-28 | Ecole Polytechnique Federale De Lausanne (Epfl) | Magnetic bead manipulation and transport device |
EP1473085B1 (de) | 2003-03-31 | 2015-07-22 | Canon Kabushiki Kaisha | Behälter für biochemische Reaktionen |
JP4260541B2 (ja) | 2003-05-12 | 2009-04-30 | 旭化成ファーマ株式会社 | 糖化タンパク質測定用試験片 |
US6916113B2 (en) | 2003-05-16 | 2005-07-12 | Agilent Technologies, Inc. | Devices and methods for fluid mixing |
AU2004240944A1 (en) | 2003-05-20 | 2004-12-02 | Fluidigm Corporation | Method and system for microfluidic device and imaging thereof |
US7648835B2 (en) | 2003-06-06 | 2010-01-19 | Micronics, Inc. | System and method for heating, cooling and heat cycling on microfluidic device |
KR101203402B1 (ko) | 2003-06-06 | 2012-11-23 | 마이크로닉스 인코포레이티드. | 마이크로 유체 장치상에서의 가열, 냉각 및 열 순환 시스템및 방법 |
DE10336849A1 (de) | 2003-08-11 | 2005-03-10 | Thinxxs Gmbh | Flusszelle |
JP2007502420A (ja) | 2003-08-12 | 2007-02-08 | マサチューセッツ インスティテュート オブ テクノロジー | サンプル調製方法および装置 |
TWI269873B (en) | 2003-08-29 | 2007-01-01 | Asahi Kasei Corp | Biosensor and method of measuring object to be measured |
CA2479452C (en) | 2003-08-30 | 2008-11-04 | F.Hoffmann-La Roche Ag | Method and device for determining analytes in a liquid |
WO2005024042A2 (en) | 2003-09-04 | 2005-03-17 | The Regents Of The University Of California | Aptamers and methods for their in vitro selection and uses thereof |
DE10352716A1 (de) | 2003-11-05 | 2005-06-16 | Einsle, Xaver | Plattform |
GB0327094D0 (en) | 2003-11-21 | 2003-12-24 | Inverness Medical Switzerland | Laminated device |
JPWO2005052578A1 (ja) | 2003-11-28 | 2007-07-12 | オリンパス株式会社 | 生体関連物質の検査装置とその反応ステージ |
CN100335784C (zh) * | 2003-12-05 | 2007-09-05 | 清华大学 | 微型薄膜泵 |
US7575862B2 (en) | 2003-12-09 | 2009-08-18 | Asiagen Corporation | Assay systems, kits and methods for detecting microorganisms |
JP4717637B2 (ja) | 2004-01-07 | 2011-07-06 | アークレイ株式会社 | 試薬部の配置を改良した分析用具および分析方法 |
US20080226500A1 (en) | 2004-01-15 | 2008-09-18 | Mitsuhiro Shikida | Chemical Analytic Apparatus and Chemical Analytic Method |
US7221455B2 (en) | 2004-01-20 | 2007-05-22 | The Regents Of The Unversity Of California | Integrated, fluorescence-detecting microanalytical system |
US20050164373A1 (en) | 2004-01-22 | 2005-07-28 | Oldham Mark F. | Diffusion-aided loading system for microfluidic devices |
EP2354256B1 (de) | 2004-02-24 | 2019-04-10 | Thermal Gradient | Vorrichtung für thermisches cycling |
EP1726940A1 (de) | 2004-03-17 | 2006-11-29 | Olympus Corporation | Lichtmessvorrichtung und lichtmessverfahren |
US7156117B2 (en) | 2004-03-31 | 2007-01-02 | Lifescan Scotland Limited | Method of controlling the movement of fluid through a microfluidic circuit using an array of triggerable passive valves |
US7588890B2 (en) | 2004-04-16 | 2009-09-15 | Wei-Sing Chu | Device for extracting biological molecules from tissue specimens and methods for preparing the same |
CN1997786A (zh) * | 2004-04-16 | 2007-07-11 | 优质无纺布公司 | 塑性可变形无纺网幅 |
DE102004021780B4 (de) | 2004-04-30 | 2008-10-02 | Siemens Ag | Verfahren und Anordnung zur DNA-Isolierung mit Trockenreagenzien |
JP3952036B2 (ja) | 2004-05-13 | 2007-08-01 | コニカミノルタセンシング株式会社 | マイクロ流体デバイス並びに試液の試験方法および試験システム |
FI20040768A0 (fi) | 2004-06-04 | 2004-06-04 | Teemu Korpimaeki | Menetelmä määritysreagenssien stabiloimiseksi, stabilisoituja määritysreagensseja sisältävä reagenssisäiliö ja sen käyttö |
JP2005345378A (ja) | 2004-06-04 | 2005-12-15 | Nippon Sheet Glass Co Ltd | 光検出装置 |
US7785535B2 (en) | 2004-06-07 | 2010-08-31 | Iquum, Inc. | Sample multiprocessing |
DE202004012163U1 (de) | 2004-07-08 | 2004-10-07 | Tecan Trading Ag | System mit Einrichtung zum Verhindern von Luftblasen in einer Hybridisierkammer |
EP1614466A3 (de) | 2004-07-08 | 2006-05-10 | Tecan Trading AG | System mit Einrichtung zum Verhindern von Luftblasen in einer Hybridisierkammer und entsprechendes Verfahren |
US7615370B2 (en) | 2004-07-08 | 2009-11-10 | Tecan Trading Ag | System having device for preventing air bubbles in a hybridization chamber and corresponding method |
WO2006018811A1 (en) | 2004-08-20 | 2006-02-23 | Instituto De Engenharia De Sistemas E Computadores Para Os Microsistemas E As Nanotecnologias (Inesc-Mn) | A bio-electronic device |
JP4375183B2 (ja) | 2004-09-22 | 2009-12-02 | ウシオ電機株式会社 | マイクロチップ |
US7550267B2 (en) | 2004-09-23 | 2009-06-23 | University Of Washington | Microscale diffusion immunoassay utilizing multivalent reactants |
WO2006035830A1 (ja) | 2004-09-30 | 2006-04-06 | Arkray, Inc. | 分析装置 |
US7832429B2 (en) | 2004-10-13 | 2010-11-16 | Rheonix, Inc. | Microfluidic pump and valve structures and fabrication methods |
JP2006122743A (ja) | 2004-10-26 | 2006-05-18 | Dainippon Screen Mfg Co Ltd | マイクロリアクタ装置 |
US20060094028A1 (en) | 2004-11-04 | 2006-05-04 | Welch Allyn, Inc. | Rapid diagnostic assay |
US20060127886A1 (en) | 2004-12-15 | 2006-06-15 | Kaylor Rosann M | Sample-efficient lateral flow immunoassay |
EP1846163A2 (de) | 2005-01-13 | 2007-10-24 | Micronics, Inc. | Mikrofluidische vorrichtung zur detektion seltener zellen |
US8985547B2 (en) | 2005-01-31 | 2015-03-24 | President And Fellows Of Harvard College | Valves and reservoirs for microfluidic systems |
JP2006227301A (ja) | 2005-02-17 | 2006-08-31 | Olympus Corp | 蛍光観察装置 |
JP2006246777A (ja) | 2005-03-10 | 2006-09-21 | Canon Inc | 生化学反応用カートリッジおよび生化学反応カートリッジ内での溶液の移動方法 |
US20070014695A1 (en) | 2005-04-26 | 2007-01-18 | Applera Corporation | Systems and Methods for Multiple Analyte Detection |
US20070042427A1 (en) | 2005-05-03 | 2007-02-22 | Micronics, Inc. | Microfluidic laminar flow detection strip |
US7635594B2 (en) | 2005-05-09 | 2009-12-22 | Theranos, Inc. | Point-of-care fluidic systems and uses thereof |
US20060254916A1 (en) | 2005-05-16 | 2006-11-16 | Hernandez Juan J | Methods of forming microfluidic devices and uses thereof |
EP1907560B1 (de) | 2005-05-20 | 2013-01-23 | Integrated DNA Technologies, Inc. | Verbindungen und verfahren zur markierung von oligonukleotiden |
WO2006125767A1 (de) | 2005-05-25 | 2006-11-30 | Siemens Aktiengesellschaft | System zur integrierten und automatisierten dna- oder protein-analyse und betriebsverfahren eines solchen systems |
CA2610875A1 (en) | 2005-06-06 | 2006-12-14 | Decision Biomarkers, Inc. | Assays based on liquid flow over arrays |
AU2006261953B2 (en) | 2005-06-24 | 2012-02-23 | Board Of Regents, The University Of Texas System | Systems and methods including self-contained cartridges with detection systems and fluid delivery systems |
US7527763B2 (en) | 2005-07-05 | 2009-05-05 | 3M Innovative Properties Company | Valve control system for a rotating multiplex fluorescence detection device |
JP4692200B2 (ja) | 2005-10-06 | 2011-06-01 | 横河電機株式会社 | 化学処理用カートリッジおよびその使用方法 |
EP1941253A1 (de) | 2005-10-25 | 2008-07-09 | Inverness Medical Switzerland GmbH | Verfahren und kit zum nachweis eines analyten in einer probe |
US20080260586A1 (en) | 2005-11-07 | 2008-10-23 | Koninklijke Philips Electronics, N.V. | Pillar Based Biosensor and Method of Making the Same |
US7763453B2 (en) | 2005-11-30 | 2010-07-27 | Micronics, Inc. | Microfluidic mixing and analytic apparatus |
US9056291B2 (en) | 2005-11-30 | 2015-06-16 | Micronics, Inc. | Microfluidic reactor system |
WO2007076549A2 (en) | 2005-12-29 | 2007-07-05 | Honeywell International Inc. | Assay implementation in a microfluidic format |
US20070154895A1 (en) | 2005-12-30 | 2007-07-05 | Caliper Life Sciences, Inc. | Multi-assay microfluidic chips |
US20090061450A1 (en) | 2006-03-14 | 2009-03-05 | Micronics, Inc. | System and method for diagnosis of infectious diseases |
JP5254949B2 (ja) | 2006-03-15 | 2013-08-07 | マイクロニクス, インコーポレイテッド | 一体型の核酸アッセイ |
WO2007109584A1 (en) | 2006-03-16 | 2007-09-27 | University Of Washington | Temperature-and ph-responsive polymer compositions |
US7967022B2 (en) | 2007-02-27 | 2011-06-28 | Deka Products Limited Partnership | Cassette system integrated apparatus |
JP2009537152A (ja) | 2006-05-17 | 2009-10-29 | カリフォルニア インスティテュート オブ テクノロジー | 温度サイクルシステム |
WO2007137291A1 (en) | 2006-05-23 | 2007-11-29 | Molecular Detection, Inc. | Ambient temperature stable kits for molecular diagnostics |
US20070280856A1 (en) | 2006-06-02 | 2007-12-06 | Applera Corporation | Devices and Methods for Controlling Bubble Formation in Microfluidic Devices |
EP2041573B1 (de) | 2006-06-23 | 2019-09-04 | PerkinElmer Health Sciences, Inc. | Verfahren und vorrichtung für mikrofluidische point-of-care-immunoassays |
US7674616B2 (en) | 2006-09-14 | 2010-03-09 | Hemosense, Inc. | Device and method for measuring properties of a sample |
US8900525B2 (en) | 2006-09-18 | 2014-12-02 | Ge Healthcare Bio-Sciences Corp. | Preparation of glassified biological reagents |
WO2008147382A1 (en) | 2006-09-27 | 2008-12-04 | Micronics, Inc. | Integrated microfluidic assay devices and methods |
US7749775B2 (en) | 2006-10-03 | 2010-07-06 | Jonathan Scott Maher | Immunoassay test device and method of use |
US7607641B1 (en) * | 2006-10-05 | 2009-10-27 | Microfluidic Systems, Inc. | Microfluidic valve mechanism |
JP4888035B2 (ja) | 2006-10-16 | 2012-02-29 | 凸版印刷株式会社 | 酸素インジケーターおよび包装材料 |
GB2443260C (en) | 2006-10-26 | 2017-11-29 | Cellnovo Ltd | Micro-valve |
US8709787B2 (en) | 2006-11-14 | 2014-04-29 | Handylab, Inc. | Microfluidic cartridge and method of using same |
CA2716575C (en) | 2007-02-23 | 2015-09-29 | Ese Embedded System Engineering Gmbh | Optical measuring instrument |
KR101334183B1 (ko) | 2007-06-01 | 2013-12-02 | 삼성전자주식회사 | 미세 반응을 위한 형광 검출 모듈과 이를 구비한 형광 검출시스템 |
JP2009014529A (ja) | 2007-07-05 | 2009-01-22 | Panasonic Corp | 分析用デバイス、分析用デバイスを用いる分析装置、および液体試料成分測定方法 |
JP2009019962A (ja) | 2007-07-11 | 2009-01-29 | Konica Minolta Medical & Graphic Inc | 蛍光検出ユニット、反応検出装置、マイクロチップ検査システム |
WO2009018473A1 (en) | 2007-07-31 | 2009-02-05 | Micronics, Inc. | Sanitary swab collection system, microfluidic assay device, and methods for diagnostic assays |
EP2040073A1 (de) | 2007-09-20 | 2009-03-25 | Iline Microsystems, S.L. | Mikrofluidische Vorrichtung und Verfahren zur Flüssigkeitsgerinnungs-Zeitbestimmung |
US7906317B2 (en) | 2007-10-21 | 2011-03-15 | King Car Food Industrial Co., Ltd. | Apparatus for thin-layer cell smear preparation and in-situ hybridization |
WO2009105711A1 (en) | 2008-02-21 | 2009-08-27 | Decision Biomarkers, Inc. | Assays based on liquid flow over arrays |
EP2586876B1 (de) | 2008-08-15 | 2014-10-08 | Cascade Biosystems, Inc. | Nukleinsäureerkennung |
US20110151479A1 (en) | 2008-08-25 | 2011-06-23 | University Of Washington | Microfluidic systems incorporating flow-through membranes |
US8404198B2 (en) | 2008-08-27 | 2013-03-26 | Life Technologies Corporation | Apparatus for and method of processing biological samples |
JP2010078508A (ja) | 2008-09-26 | 2010-04-08 | Toshiba Corp | 送液装置 |
WO2010036072A2 (ko) | 2008-09-29 | 2010-04-01 | 전남대학교산학협력단 | 스냅-스루를 이용한 마이크로 펌프 |
WO2010040103A1 (en) | 2008-10-03 | 2010-04-08 | Micronics, Inc. | Microfluidic apparatus and methods for performing blood typing and crossmatching |
EP2202328A1 (de) | 2008-12-26 | 2010-06-30 | Fundacion Inasmet | Verfahren zum Gewinnen von Beschichtungen zum Schutz gegen hohe Temperaturen und hohe Rauheit und gewonnene Beschichtung |
JP5715068B2 (ja) | 2009-01-30 | 2015-05-07 | マイクロニクス, インコーポレイテッド | 携帯型高利得蛍光検出システム |
EP2412020B1 (de) | 2009-03-24 | 2020-09-30 | University Of Chicago | Schiebe- und schneidevorrichtung und entsprechende verfahren |
CN102448612B (zh) | 2009-04-13 | 2014-12-03 | 精密公司 | 微流体临床分析器 |
WO2010141326A1 (en) | 2009-06-02 | 2010-12-09 | Integenx Inc. | Fluidic devices with diaphragm valves |
CN102803507B (zh) | 2009-06-12 | 2016-05-25 | 精密公司 | 用于微流体装置中在板反应剂的脱水储存的组合物及方法 |
JP5116114B2 (ja) | 2009-07-27 | 2013-01-09 | 富士フイルム株式会社 | マイクロ化学装置の運転方法 |
WO2012071069A1 (en) | 2010-11-23 | 2012-05-31 | Cyvek, Inc. | Method and apparatus for performing assays |
KR101851117B1 (ko) * | 2010-01-29 | 2018-04-23 | 마이크로닉스 인코포레이티드. | 샘플-투-앤서 마이크로유체 카트리지 |
EP2616797B1 (de) | 2010-09-15 | 2017-01-11 | MBIO Diagnostics Inc. | System und verfahren zur detektion von mehreren molekülen in einem assay |
WO2012055446A1 (en) | 2010-10-29 | 2012-05-03 | Nokia Siemens Networks Gmbh & Co. Kg. | Dynamic creation of virtualized network topology |
EP2471652A1 (de) | 2010-12-28 | 2012-07-04 | Nordenia Technologies GmbH | Elastomerer Schichtstoff und Verfahren zu seiner Herstellung |
PT2676136T (pt) | 2011-02-15 | 2021-03-25 | Hemosonics Llc | Dispositivos, sistemas e métodos para avaliação de hemostasia |
EP2734281A1 (de) | 2011-07-20 | 2014-05-28 | Qiagen GmbH | Filterungsvorrichtungen mit tonmineralien |
US20130032235A1 (en) | 2011-08-02 | 2013-02-07 | Teledyne Dalsa Semiconductor, Inc. | Integrated microfluidic check valve and device including such a check valve |
MX344792B (es) | 2011-09-25 | 2017-01-06 | Theranos Inc | Sistemas y métodos para múltiples análisis. |
US8894946B2 (en) | 2011-10-21 | 2014-11-25 | Integenx Inc. | Sample preparation, processing and analysis systems |
JP6190822B2 (ja) | 2012-01-09 | 2017-08-30 | マイクロニクス, インコーポレイテッド | マイクロ流体リアクタシステム |
US9716892B2 (en) | 2012-07-02 | 2017-07-25 | Qualcomm Incorporated | Video parameter set including session negotiation information |
US10065186B2 (en) | 2012-12-21 | 2018-09-04 | Micronics, Inc. | Fluidic circuits and related manufacturing methods |
EP3549674B1 (de) | 2012-12-21 | 2020-08-12 | PerkinElmer Health Sciences, Inc. | Filme mit geringere elastizität zur mikrofluidischen verwendung |
WO2014100725A1 (en) | 2012-12-21 | 2014-06-26 | Micronics, Inc. | Portable fluorescence detection system and microassay cartridge |
JP6472788B2 (ja) | 2013-05-07 | 2019-02-20 | マイクロニクス, インコーポレイテッド | 粘土鉱物およびアルカリ性溶液を使用して核酸含有試料を調製するための方法 |
JP6484222B2 (ja) | 2013-05-07 | 2019-03-13 | マイクロニクス, インコーポレイテッド | 核酸の調製および分析のためのデバイス |
WO2015191916A1 (en) | 2014-06-11 | 2015-12-17 | Micronics, Inc. | Microfluidic cartridges and apparatus with integrated assay controls for analysis of nucleic acids |
-
2013
- 2013-12-20 EP EP19175141.1A patent/EP3549674B1/de active Active
- 2013-12-20 CN CN201711024398.2A patent/CN107824233B/zh active Active
- 2013-12-20 EP EP13865758.0A patent/EP2934751B1/de active Active
- 2013-12-20 WO PCT/US2013/077269 patent/WO2014100743A2/en active Application Filing
- 2013-12-20 JP JP2015549835A patent/JP6935167B2/ja active Active
- 2013-12-20 KR KR1020157019644A patent/KR20150096788A/ko not_active Application Discontinuation
- 2013-12-20 US US14/653,737 patent/US10518262B2/en active Active
- 2013-12-20 CN CN201380072973.XA patent/CN104994957B/zh active Active
-
2019
- 2019-06-14 JP JP2019111060A patent/JP7022720B2/ja active Active
- 2019-11-08 US US16/679,076 patent/US11181105B2/en active Active
-
2021
- 2021-12-13 JP JP2021201745A patent/JP2022048141A/ja not_active Withdrawn
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0399859A1 (de) * | 1989-05-22 | 1990-11-28 | Clextral | Vorrichtung zum Messen der Scherbelastung von in Extrudern behandelter Materie |
EP0517631A1 (de) * | 1991-06-07 | 1992-12-09 | Transfluid Sa | Ventil mit metallischer Membran |
US6007309A (en) * | 1995-12-13 | 1999-12-28 | Hartley; Frank T. | Micromachined peristaltic pumps |
WO2003101887A2 (en) * | 2002-06-03 | 2003-12-11 | Ing. Ilja Krejci - Engineering | Three-dimentional components prepared by thick film technology and method of producing thereof |
JP2006073371A (ja) * | 2004-09-02 | 2006-03-16 | Toray Ind Inc | 高分子電解質材、ならびにそれを用いた高分子電解質膜、膜電極複合体および高分子電解質型燃料電池 |
US20070234785A1 (en) * | 2006-03-30 | 2007-10-11 | Timothy Beerling | System and method for using a flexible membrane for controlling fluid flow in a microfluidic circuit |
Also Published As
Publication number | Publication date |
---|---|
JP6935167B2 (ja) | 2021-09-15 |
CN104994957A (zh) | 2015-10-21 |
US10518262B2 (en) | 2019-12-31 |
JP2022048141A (ja) | 2022-03-25 |
CN104994957B (zh) | 2017-11-28 |
KR20150096788A (ko) | 2015-08-25 |
JP7022720B2 (ja) | 2022-02-18 |
WO2014100743A3 (en) | 2014-08-07 |
JP2016508197A (ja) | 2016-03-17 |
CN107824233A (zh) | 2018-03-23 |
JP2019190465A (ja) | 2019-10-31 |
US11181105B2 (en) | 2021-11-23 |
EP2934751B1 (de) | 2019-05-29 |
US20200070154A1 (en) | 2020-03-05 |
CN107824233B (zh) | 2020-06-30 |
EP3549674A1 (de) | 2019-10-09 |
US20150321193A1 (en) | 2015-11-12 |
EP3549674B1 (de) | 2020-08-12 |
WO2014100743A2 (en) | 2014-06-26 |
EP2934751A2 (de) | 2015-10-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP2934751A4 (de) | Filme mit geringere elastizität zur mikrofluidischen verwendung | |
ZA201504434B (en) | Energy-efficient film | |
HRP20171401T1 (hr) | Jednokratni uređaj za anastomozu za obrezivanje | |
IL236385A0 (en) | Device context setting | |
EP2918380A4 (de) | Rasierer | |
GB201201578D0 (en) | Polymer | |
GB2507632B (en) | Plastic film | |
EP2918383A4 (de) | Rasierer | |
EP2942180A4 (de) | Film zum formen | |
GB2513034B (en) | Polymer | |
EP2933013A4 (de) | Wasserstofffreisetzender film | |
HK1191696A1 (zh) | 防塵薄膜組件 | |
GB201216800D0 (en) | Novel use | |
GB201222958D0 (en) | Film | |
GB201411209D0 (en) | Polymer | |
GB2505524B (en) | Position determination | |
EP2818515A4 (de) | Fluorharzfilm | |
GB201222955D0 (en) | Film | |
DK2938489T3 (en) | Plastic film | |
GB2506739B (en) | Dialysis device | |
EP2926988A4 (de) | Kosmetikfilm | |
EP2896646A4 (de) | Orientierte folie | |
GB201211729D0 (en) | Plastic slide | |
GB201206393D0 (en) | Use | |
GB201205422D0 (en) | Thin device |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20150713 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
AX | Request for extension of the european patent |
Extension state: BA ME |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: BRAGD, MATTHEW, SCOTT Inventor name: KAY, JUSTIN, L. Inventor name: BATTRELL, C., FREDERICK Inventor name: SPRAGUE, ISAAC |
|
DAX | Request for extension of the european patent (deleted) | ||
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: BATTRELL, C., FREDERICK Inventor name: SPRAGUE, ISAAC Inventor name: BRAGD, MATTHEW, SCOTT Inventor name: KAY, JUSTIN, L. |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: B01L 3/00 20060101AFI20160706BHEP |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20161014 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: B01L 3/00 20060101AFI20161010BHEP |
|
RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: MICRONICS, INC. |
|
GRAP | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOSNIGR1 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: GRANT OF PATENT IS INTENDED |
|
INTG | Intention to grant announced |
Effective date: 20181212 |
|
GRAS | Grant fee paid |
Free format text: ORIGINAL CODE: EPIDOSNIGR3 |
|
GRAA | (expected) grant |
Free format text: ORIGINAL CODE: 0009210 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE PATENT HAS BEEN GRANTED |
|
AK | Designated contracting states |
Kind code of ref document: B1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
REG | Reference to a national code |
Ref country code: GB Ref legal event code: FG4D |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: EP |
|
RAP2 | Party data changed (patent owner data changed or rights of a patent transferred) |
Owner name: PERKINELMER HEALTH SCIENCES, INC. |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R096 Ref document number: 602013056085 Country of ref document: DE |
|
REG | Reference to a national code |
Ref country code: AT Ref legal event code: REF Ref document number: 1137957 Country of ref document: AT Kind code of ref document: T Effective date: 20190615 |
|
REG | Reference to a national code |
Ref country code: IE Ref legal event code: FG4D |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: NV Representative=s name: BOVARD AG PATENT- UND MARKENANWAELTE, CH |
|
REG | Reference to a national code |
Ref country code: NL Ref legal event code: MP Effective date: 20190529 |
|
REG | Reference to a national code |
Ref country code: LT Ref legal event code: MG4D |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: FI Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20190529 Ref country code: NO Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20190829 Ref country code: PT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20190930 Ref country code: AL Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20190529 Ref country code: SE Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20190529 Ref country code: LT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20190529 Ref country code: HR Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20190529 Ref country code: ES Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20190529 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: GR Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20190830 Ref country code: BG Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20190829 Ref country code: LV Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20190529 Ref country code: RS Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20190529 |
|
REG | Reference to a national code |
Ref country code: AT Ref legal event code: MK05 Ref document number: 1137957 Country of ref document: AT Kind code of ref document: T Effective date: 20190529 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: CZ Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20190529 Ref country code: RO Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20190529 Ref country code: EE Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20190529 Ref country code: DK Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20190529 Ref country code: AT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20190529 Ref country code: NL Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20190529 Ref country code: SK Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20190529 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: IT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20190529 Ref country code: SM Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20190529 |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R097 Ref document number: 602013056085 Country of ref document: DE |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: TR Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20190529 |
|
PLBE | No opposition filed within time limit |
Free format text: ORIGINAL CODE: 0009261 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: PL Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20190529 |
|
26N | No opposition filed |
Effective date: 20200303 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: SI Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20190529 |
|
REG | Reference to a national code |
Ref country code: BE Ref legal event code: MM Effective date: 20191231 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: MC Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20190529 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: LU Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20191220 Ref country code: IE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20191220 Ref country code: FR Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20191231 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: BE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20191231 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: CY Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20190529 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: IS Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20190929 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: MT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20190529 Ref country code: HU Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT; INVALID AB INITIO Effective date: 20131220 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: MK Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20190529 |
|
P01 | Opt-out of the competence of the unified patent court (upc) registered |
Effective date: 20230526 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: GB Payment date: 20231026 Year of fee payment: 11 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: DE Payment date: 20231024 Year of fee payment: 11 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: CH Payment date: 20240101 Year of fee payment: 11 |