EP1908488A3 - Metered dose inhaler for salmeterol - Google Patents

Metered dose inhaler for salmeterol Download PDF

Info

Publication number
EP1908488A3
EP1908488A3 EP07025253A EP07025253A EP1908488A3 EP 1908488 A3 EP1908488 A3 EP 1908488A3 EP 07025253 A EP07025253 A EP 07025253A EP 07025253 A EP07025253 A EP 07025253A EP 1908488 A3 EP1908488 A3 EP 1908488A3
Authority
EP
European Patent Office
Prior art keywords
fluorocarbon
salmeterol
metered dose
polymer
dose inhaler
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP07025253A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP1908488A2 (en
Inventor
Ignatius Loy Britto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline LLC
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27025573&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EP1908488(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of EP1908488A2 publication Critical patent/EP1908488A2/en
Publication of EP1908488A3 publication Critical patent/EP1908488A3/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/14—Containers for dispensing liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant
    • B65D83/44—Valves specially adapted for the discharge of contents; Regulating devices
    • B65D83/52—Metering valves; Metering devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/02—General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0222—Materials for reducing friction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/02—General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0233—Conductive materials, e.g. antistatic coatings for spark prevention

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mechanical Engineering (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
EP07025253A 1995-04-14 1996-04-10 Metered dose inhaler for salmeterol Ceased EP1908488A3 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US42237095A 1995-04-14 1995-04-14
US58333296A 1996-01-05 1996-01-05
EP05075583A EP1547636A1 (en) 1995-04-14 1996-04-10 Metered dose inhaler for salmeterol
EP96911712A EP0820323B1 (en) 1995-04-14 1996-04-10 Metered dose inhaler for salmeterol
EP03017935A EP1366777B1 (en) 1995-04-14 1996-04-10 Metered dose inhaler for salmeterol

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
EP05075583A Division EP1547636A1 (en) 1995-04-14 1996-04-10 Metered dose inhaler for salmeterol

Publications (2)

Publication Number Publication Date
EP1908488A2 EP1908488A2 (en) 2008-04-09
EP1908488A3 true EP1908488A3 (en) 2008-04-16

Family

ID=27025573

Family Applications (4)

Application Number Title Priority Date Filing Date
EP05075583A Withdrawn EP1547636A1 (en) 1995-04-14 1996-04-10 Metered dose inhaler for salmeterol
EP96911712A Revoked EP0820323B1 (en) 1995-04-14 1996-04-10 Metered dose inhaler for salmeterol
EP03017935A Expired - Lifetime EP1366777B1 (en) 1995-04-14 1996-04-10 Metered dose inhaler for salmeterol
EP07025253A Ceased EP1908488A3 (en) 1995-04-14 1996-04-10 Metered dose inhaler for salmeterol

Family Applications Before (3)

Application Number Title Priority Date Filing Date
EP05075583A Withdrawn EP1547636A1 (en) 1995-04-14 1996-04-10 Metered dose inhaler for salmeterol
EP96911712A Revoked EP0820323B1 (en) 1995-04-14 1996-04-10 Metered dose inhaler for salmeterol
EP03017935A Expired - Lifetime EP1366777B1 (en) 1995-04-14 1996-04-10 Metered dose inhaler for salmeterol

Country Status (31)

Country Link
US (2) US6143277A (cs)
EP (4) EP1547636A1 (cs)
JP (1) JPH11509434A (cs)
KR (1) KR100403899B1 (cs)
CN (1) CN1142798C (cs)
AP (1) AP979A (cs)
AT (2) ATE250439T1 (cs)
AU (1) AU718263B2 (cs)
BG (1) BG64117B1 (cs)
BR (1) BR9604977A (cs)
CA (1) CA2217954C (cs)
CY (1) CY2479B1 (cs)
CZ (1) CZ296209B6 (cs)
DE (2) DE69634865D1 (cs)
DK (1) DK0820323T3 (cs)
EA (1) EA000892B1 (cs)
EE (1) EE04005B1 (cs)
ES (1) ES2206572T3 (cs)
HU (1) HUP9802391A3 (cs)
IS (1) IS4579A (cs)
MX (1) MX9707864A (cs)
NO (1) NO974736L (cs)
NZ (1) NZ306280A (cs)
OA (1) OA10626A (cs)
PL (1) PL180901B1 (cs)
PT (1) PT820323E (cs)
RO (1) RO119116B1 (cs)
SK (1) SK284447B6 (cs)
TR (1) TR199701169T1 (cs)
UA (1) UA54386C2 (cs)
WO (1) WO1996032150A1 (cs)

Families Citing this family (158)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5270305A (en) * 1989-09-08 1993-12-14 Glaxo Group Limited Medicaments
EP1769819A3 (en) * 1995-04-14 2013-05-22 GlaxoSmithKline LLC Metered dose inhaler for fluticasone propionate
DK0820279T3 (da) * 1995-04-14 2002-10-07 Smithkline Beecham Corp Dosisudmålende inhalator til Albuterol
EE9700372A (et) * 1995-04-14 1998-06-15 Glaxo Wellcome Inc. Beklometasoondipropionaadi doseeriv inhalaator
PL180901B1 (pl) * 1995-04-14 2001-04-30 Glaxo Wellcome Inc Inhalator z dozymetrem
GB9526392D0 (en) 1995-12-22 1996-02-21 Glaxo Group Ltd Medicaments
US6413496B1 (en) * 1996-12-04 2002-07-02 Biogland Ireland (R&D) Limited Pharmaceutical compositions and devices for their administration
US6120752A (en) * 1997-05-21 2000-09-19 3M Innovative Properties Company Medicinal aerosol products containing formulations of ciclesonide and related steroids
US20010031244A1 (en) 1997-06-13 2001-10-18 Chiesi Farmaceutici S.P.A. Pharmaceutical aerosol composition
GB2332712A (en) * 1997-07-29 1999-06-30 Glaxo Group Ltd Valve for aerosol container
DE19860969B4 (de) * 1997-09-03 2006-03-09 Glaxo Group Ltd., Greenford Dosierventil für einen Druck-Abgabe-Behälter
US20030103906A1 (en) * 1997-10-14 2003-06-05 Smithkline Beecham Corporation Metered dose inhaler having internal surfaces coated with fluorocarbon polymer
US6086376A (en) * 1998-01-30 2000-07-11 Rtp Pharma Inc. Dry aerosol suspension of phospholipid-stabilized drug microparticles in a hydrofluoroalkane propellant
GB9814717D0 (en) * 1998-02-23 1998-09-02 Bespak Plc Improvements in drug delivery devices
ATE415993T1 (de) † 1998-02-23 2008-12-15 Bespak Plc Abgabevorrichtungen für artzneimittel
GB9805938D0 (en) * 1998-03-19 1998-05-13 Glaxo Group Ltd Valve for aerosol container
GB9808802D0 (en) * 1998-04-24 1998-06-24 Glaxo Group Ltd Pharmaceutical formulations
GB2340759B (en) * 1998-08-26 2003-05-07 Bespak Plc Improvements in drug delivery devices
DZ2947A1 (fr) 1998-11-25 2004-03-15 Chiesi Farma Spa Inhalateur à compteur de dose sous pression.
US6390291B1 (en) 1998-12-18 2002-05-21 Smithkline Beecham Corporation Method and package for storing a pressurized container containing a drug
US6315112B1 (en) 1998-12-18 2001-11-13 Smithkline Beecham Corporation Method and package for storing a pressurized container containing a drug
US6352152B1 (en) 1998-12-18 2002-03-05 Smithkline Beecham Corporation Method and package for storing a pressurized container containing a drug
GB9913932D0 (en) * 1999-06-15 1999-08-18 Pfizer Ltd Purine derivatives
US6315985B1 (en) 1999-06-18 2001-11-13 3M Innovative Properties Company C-17/21 OH 20-ketosteroid solution aerosol products with enhanced chemical stability
ES2165768B1 (es) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
US7214687B2 (en) 1999-07-14 2007-05-08 Almirall Ag Quinuclidine derivatives and medicinal compositions containing the same
IT1313553B1 (it) 1999-07-23 2002-09-09 Chiesi Farma Spa Formulazioni ottimizzate costituite da soluzioni di steroidi dasomministrare per inalazione.
GB9924992D0 (en) * 1999-10-21 1999-12-22 Glaxo Group Ltd Pharmaceutical aerosol formulations
IT1317720B1 (it) * 2000-01-07 2003-07-15 Chiesi Farma Spa Dispositivo per la somministrazione di aerosol dosati pressurizzati inpropellenti idrofluoroalcani.
IL150397A0 (en) * 2000-01-14 2002-12-01 Astrazeneca Ab A method for applying a polymer coating to the internal surface of a container
IT1317846B1 (it) 2000-02-22 2003-07-15 Chiesi Farma Spa Formulazioni contenenti un farmaco anticolinergico per il trattamentodella broncopneumopatia cronica ostruttiva.
AU3400501A (en) 2000-02-28 2001-09-12 Vectura Ltd Improvements in or relating to the delivery of oral drugs
WO2001064524A2 (en) 2000-03-01 2001-09-07 Glaxo Group Limited Metered dose inhaler
EP1259277A1 (en) * 2000-03-01 2002-11-27 Glaxo Group Limited Metered dose inhaler
US20030145850A1 (en) * 2000-03-01 2003-08-07 Hailey Mark Andrew Metered dose inhaler
US6971383B2 (en) * 2001-01-24 2005-12-06 University Of North Carolina At Chapel Hill Dry powder inhaler devices, multi-dose dry powder drug packages, control systems, and associated methods
IT1318514B1 (it) * 2000-05-12 2003-08-27 Chiesi Farma Spa Formulazioni contenenti un farmaco glucocorticosteroide per iltrattamento di patologie broncopolmonari.
CZ303833B6 (cs) * 2000-05-22 2013-05-22 Chiesi Farmaceutici S.P.A. Aerosolový prostredek
DK1284771T3 (da) * 2000-05-23 2006-04-18 Glaxo Group Ltd Aerosolbeholder til formuleringer af salmeterol-xinafoat
AU2001270074A1 (en) 2000-06-22 2002-01-02 Glaxo Group Limited Method and package for storing a pressurized container containing a drug
GB2367011A (en) * 2000-08-26 2002-03-27 Glaxo Group Ltd Metered dose inhaler for salmeterol
EP1318952A2 (en) * 2000-09-18 2003-06-18 Glaxo Group Limited Coated can for a metered dose inhaler
WO2002030499A2 (en) * 2000-10-13 2002-04-18 Glaxo Group Limited Medicament dispenser
SE0004610D0 (sv) 2000-12-13 2000-12-13 Astrazeneca Ab Surface modification process
US7247704B2 (en) 2000-12-18 2007-07-24 Arriva Pharmaceuticals, Inc. Multifunctional protease inhibitors and their use in treatment of disease
SE0004750D0 (sv) * 2000-12-19 2000-12-19 Astrazeneca Ab Novel formulation
MXPA03005697A (es) * 2000-12-22 2003-10-06 Glaxo Group Ltd Inhalador de dosis medida para xinafoato de salmeterol.
GB0105560D0 (en) * 2001-03-07 2001-04-25 Glaxo Group Ltd Pharmaceutical formulations
US6455028B1 (en) 2001-04-23 2002-09-24 Pharmascience Ipratropium formulation for pulmonary inhalation
US20030051728A1 (en) 2001-06-05 2003-03-20 Lloyd Peter M. Method and device for delivering a physiologically active compound
US7090830B2 (en) 2001-05-24 2006-08-15 Alexza Pharmaceuticals, Inc. Drug condensation aerosols and kits
US7645442B2 (en) 2001-05-24 2010-01-12 Alexza Pharmaceuticals, Inc. Rapid-heating drug delivery article and method of use
US7458374B2 (en) 2002-05-13 2008-12-02 Alexza Pharmaceuticals, Inc. Method and apparatus for vaporizing a compound
US7585493B2 (en) 2001-05-24 2009-09-08 Alexza Pharmaceuticals, Inc. Thin-film drug delivery article and method of use
US20070122353A1 (en) 2001-05-24 2007-05-31 Hale Ron L Drug condensation aerosols and kits
TR200401980T4 (tr) 2001-07-02 2004-09-21 Chiesi Farmaceutici S.P.A. Aerosol olarak uygulama için en uygun hale getirilmiş tobramisin formülasyonu
WO2003006181A1 (en) * 2001-07-10 2003-01-23 3M Innovative Properties Company Coated medicinal inhalation devices and components method
GB0125380D0 (en) * 2001-10-23 2001-12-12 Glaxo Group Ltd Medicament dispenser
US6974803B2 (en) * 2001-12-06 2005-12-13 Pfizer Inc Pharmaceutical combination
GB0129397D0 (en) * 2001-12-07 2002-01-30 Pfizer Ltd Pharmaceutical combination
US6889690B2 (en) 2002-05-10 2005-05-10 Oriel Therapeutics, Inc. Dry powder inhalers, related blister devices, and associated methods of dispensing dry powder substances and fabricating blister packages
US6985798B2 (en) 2002-05-10 2006-01-10 Oriel Therapeutics, Inc. Dry powder dose filling systems and related methods
US7118010B2 (en) 2002-05-10 2006-10-10 Oriel Therapeutics, Inc. Apparatus, systems and related methods for dispensing and /or evaluating dry powders
US7677411B2 (en) 2002-05-10 2010-03-16 Oriel Therapeutics, Inc. Apparatus, systems and related methods for processing, dispensing and/or evaluatingl dry powders
AU2003251760A1 (en) 2002-06-27 2004-01-19 Oriel Therapeutics, Inc. Apparatus and methods for dispensing dry powders
AR040661A1 (es) * 2002-07-26 2005-04-13 Theravance Inc Diclorhidrato cristalino de n-{2-[-((r)-2-hidroxi-2-feniletilamino)fenil]etil}-(r)-2hidroxi-2-(3-formamido-4-hidroxifenil)etilamina, agonista del receptor adrenergico beta 2
US20040105818A1 (en) 2002-11-26 2004-06-03 Alexza Molecular Delivery Corporation Diuretic aerosols and methods of making and using them
US7913688B2 (en) 2002-11-27 2011-03-29 Alexza Pharmaceuticals, Inc. Inhalation device for producing a drug aerosol
JP2006511297A (ja) * 2002-12-18 2006-04-06 グラクソ　グループ　リミテッド ベント型マウスピースを有する投薬システム
EP1587482A4 (en) * 2003-01-31 2010-08-25 Technion Res & Dev Foundation INFLAMMATORY COMPOSITIONS AND ITS USES
PE20040950A1 (es) 2003-02-14 2005-01-01 Theravance Inc DERIVADOS DE BIFENILO COMO AGONISTAS DE LOS RECEPTORES ADRENERGICOS ß2 Y COMO ANTAGONISTAS DE LOS RECEPTORES MUSCARINICOS
US20040226556A1 (en) 2003-05-13 2004-11-18 Deem Mark E. Apparatus for treating asthma using neurotoxin
JP2006527237A (ja) 2003-06-13 2006-11-30 アルタナ　ファルマ　アクチエンゲゼルシャフト ホルモテロールと及びシクレソニドの組合せ物
JP4607112B2 (ja) 2003-08-11 2011-01-05 グラクソ グループ リミテッド 医薬定量噴霧式吸入器及び前記吸引器に関連する方法
ES2668780T3 (es) 2003-08-29 2018-05-22 Glaxo Group Limited Inhalador de dosificación farmacéutica medida y procedimientos relacionados con el mismo
EP1670482B2 (en) 2003-09-16 2022-06-29 Covis Pharma B.V. Use of ciclesonide for the treatment of respiratory diseases
US7451761B2 (en) 2003-10-27 2008-11-18 Oriel Therapeutics, Inc. Dry powder inhalers, related blister package indexing and opening mechanisms, and associated methods of dispensing dry powder substances
US7377277B2 (en) 2003-10-27 2008-05-27 Oriel Therapeutics, Inc. Blister packages with frames and associated methods of fabricating dry powder drug containment systems
JP2007509941A (ja) * 2003-10-28 2007-04-19 グラクソ　グループ　リミテッド ラクトース無水物を用いる吸入医薬製剤およびその投与方法
WO2005044186A2 (en) * 2003-10-28 2005-05-19 Glaxo Group Limited Inhalable pharmaceutical formulations employing desiccating agents and methods of administering the same
EP1595531A1 (en) 2004-05-13 2005-11-16 CHIESI FARMACEUTICI S.p.A. Stable pharmaceutical solution formulations for pressurized metered dose inhalers
TWI341836B (en) 2004-03-11 2011-05-11 Theravance Inc Biphenyl compounds useful as muscarinic receptor antagonists
EP1732526A2 (en) * 2004-03-12 2006-12-20 Cipla Ltd. Salmeterol inhalation formulations
PL1905451T3 (pl) 2004-05-31 2010-05-31 Almirall Sa Kombinacje obejmujące środki przeciwmuskarynowe i kortykosteroidy
ES2257152B1 (es) 2004-05-31 2007-07-01 Laboratorios Almirall S.A. Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos.
US20060120972A1 (en) * 2004-11-09 2006-06-08 Peter Engels 9-(N-methyl-piperidyliden-4)-thioxanthene for treatment of pulmonary hypertension
US9365905B2 (en) * 2005-02-10 2016-06-14 Dmv-Fonterra Excipients Technology Gmbh Processes for making lactose utilizing pre-classification techniques and pharmaceutical formulations formed therefrom
EP1858528A2 (en) * 2005-02-10 2007-11-28 Glaxo Group Limited Process for crystallizing lactose particles for use in pharmaceutical formulations
ES2265276B1 (es) 2005-05-20 2008-02-01 Laboratorios Almirall S.A. Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor beta2 adrenergico.
ES2298049B1 (es) 2006-07-21 2009-10-20 Laboratorios Almirall S.A. Procedimiento para fabricar bromuro de 3(r)-(2-hidroxi-2,2-ditien-2-ilacetoxi)-1-(3-fenoxipropil)-1-azoniabiciclo (2.2.2) octano.
ES2306595B1 (es) 2007-02-09 2009-09-11 Laboratorios Almirall S.A. Sal de napadisilato de 5-(2-((6-(2,2-difluoro-2-feniletoxi)hexil)amino)-1-hidroxietil)-8-hidroxiquinolin-2(1h)-ona como agonista del receptor adrenergico beta2.
HUE026884T2 (en) 2007-02-11 2016-08-29 Map Pharmaceuticals Inc DHE is a therapeutic method of administration for the rapid relief of migraine while minimizing side effects
WO2008112661A2 (en) 2007-03-09 2008-09-18 Alexza Pharmaceuticals, Inc. Heating unit for use in a drug delivery device
GB0721737D0 (en) 2007-11-06 2007-12-19 3M Innovative Properties Co Medicinal inhalation devices and components thereof
EP2205302A4 (en) 2007-11-06 2010-12-29 3M Innovative Properties Co MEDICAL INHALATION DEVICES AND COMPONENTS THEREOF
GB0721739D0 (en) 2007-11-06 2007-12-19 3M Innovative Properties Co medicinal inhalation devices and components thereof
ES2320961B1 (es) 2007-11-28 2010-03-17 Laboratorios Almirall, S.A. Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor adrenergico beta2.
US8483831B1 (en) 2008-02-15 2013-07-09 Holaira, Inc. System and method for bronchial dilation
EP2096105A1 (en) 2008-02-28 2009-09-02 Laboratorios Almirall, S.A. Derivatives of 4-(2-amino-1-hydroxyethyl)phenol as agonists of the b2 adrenergic receptor
EP2100599A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2100598A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
WO2009137819A1 (en) 2008-05-09 2009-11-12 Innovative Pulmonary Solutions, Inc. Systems, assemblies, and methods for treating a bronchial tree
EP2221297A1 (en) 2009-02-18 2010-08-25 Almirall, S.A. 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one and its use in the treatment of pulmonary diseases
EP2221055A1 (en) 2009-02-18 2010-08-25 Almirall, S.A. 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one for the treatment of lung function
EP2226323A1 (en) 2009-02-27 2010-09-08 Almirall, S.A. New tetrahydropyrazolo[3,4-c]isoquinolin-5-amine derivatives
EP2228368A1 (en) 2009-03-12 2010-09-15 Almirall, S.A. Process for manufacturing 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one
BRPI1007653A2 (pt) 2009-05-06 2019-09-24 3M Innovative Properties Co "dispositivos para inalação de insumos medicinais e componentes dos mesmos"
CA2760801A1 (en) 2009-05-06 2010-11-11 3M Innovative Properties Company Medicinal inhalation device
WO2010129783A1 (en) 2009-05-06 2010-11-11 3M Innovative Properties Company Apparatus and method for plasma treatment of containers
CA2989129C (en) 2009-07-15 2021-03-09 Theravance Biopharma R&D Ip, Llc Crystalline freebase forms of a biphenyl compound
GB0918150D0 (en) 2009-10-16 2009-12-02 Jagotec Ag Improved formulations
GB0918149D0 (en) 2009-10-16 2009-12-02 Jagotec Ag Improved medicinal aerosol formulation
US9649153B2 (en) 2009-10-27 2017-05-16 Holaira, Inc. Delivery devices with coolable energy emitting assemblies
US8911439B2 (en) 2009-11-11 2014-12-16 Holaira, Inc. Non-invasive and minimally invasive denervation methods and systems for performing the same
CN102711645B (zh) 2009-11-11 2016-12-28 赫莱拉公司 用于处理组织和控制狭窄的系统和装置
RU2012125043A (ru) 2009-11-17 2013-12-27 Сипла Лимитед Ингаляционные растворы
EP2380890A1 (en) 2010-04-23 2011-10-26 Almirall, S.A. New 7,8-dihydro-1,6-naphthyridin-5(6h)-one-derivatives as PDE4 inhibitors
EP2386555A1 (en) 2010-05-13 2011-11-16 Almirall, S.A. New cyclohexylamine derivatives having beta2 adrenergic agonist and m3 muscarinic antagonist activities
EP2394998A1 (en) 2010-05-31 2011-12-14 Almirall, S.A. 3-(5-Amino-6-oxo-1,6-dihydropyridazin-3-yl)-biphenyl derivatives as PDE4 inhibitors
CN102416179B (zh) 2010-09-28 2014-05-07 益得生物科技股份有限公司 用于哮喘的吸入性复方组合物
EP2441755A1 (en) 2010-09-30 2012-04-18 Almirall, S.A. Pyridine- and isoquinoline-derivatives as Syk and JAK kinase inhibitors
USD666097S1 (en) 2010-11-01 2012-08-28 Colgate-Palmolive Company Cap for a container
USD666493S1 (en) 2010-11-01 2012-09-04 Colgate-Palmolive Company Cap for a container
USD666492S1 (en) 2010-11-01 2012-09-04 Colgate-Palmolive Company Cap for a container
USD666099S1 (en) 2010-11-01 2012-08-28 Colgate-Palmolive Company Cap for a container
USD666096S1 (en) 2010-11-01 2012-08-28 Colgate-Palmolive Company Cap for a container
USD666098S1 (en) 2010-11-01 2012-08-28 Colgate-Palmolive Company Cap for a container
EP2457900A1 (en) 2010-11-25 2012-05-30 Almirall, S.A. New pyrazole derivatives having CRTh2 antagonistic behaviour
EP2463289A1 (en) 2010-11-26 2012-06-13 Almirall, S.A. Imidazo[1,2-b]pyridazine derivatives as JAK inhibitors
EP2489663A1 (en) 2011-02-16 2012-08-22 Almirall, S.A. Compounds as syk kinase inhibitors
EP2510928A1 (en) 2011-04-15 2012-10-17 Almirall, S.A. Aclidinium for use in improving the quality of sleep in respiratory patients
EP2518071A1 (en) 2011-04-29 2012-10-31 Almirall, S.A. Imidazopyridine derivatives as PI3K inhibitors
EP2518070A1 (en) 2011-04-29 2012-10-31 Almirall, S.A. Pyrrolotriazinone derivatives as PI3K inhibitors
EP2527344A1 (en) 2011-05-25 2012-11-28 Almirall, S.A. Pyridin-2(1H)-one derivatives useful as medicaments for the treatment of myeloproliferative disorders, transplant rejection, immune-mediated and inflammatory diseases
EP2526945A1 (en) 2011-05-25 2012-11-28 Almirall, S.A. New CRTH2 Antagonists
EP2548876A1 (en) 2011-07-18 2013-01-23 Almirall, S.A. New CRTh2 antagonists
EP2548863A1 (en) 2011-07-18 2013-01-23 Almirall, S.A. New CRTh2 antagonists.
EP2554544A1 (en) 2011-08-01 2013-02-06 Almirall, S.A. Pyridin-2(1h)-one derivatives as jak inhibitors
EP2744479A1 (en) 2011-08-18 2014-06-25 Takeda GmbH Pharmaceutical aerosol product for administration by oral or nasal inhalation
EP2578570A1 (en) 2011-10-07 2013-04-10 Almirall, S.A. Novel process for preparing 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1(r)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one via novel intermediates of synthesis.
CN102366406B (zh) * 2011-10-21 2013-10-09 江苏长风药业有限公司 以氢氟烷烃为抛射剂的沙美特罗替卡松气雾剂制剂
EP2592078A1 (en) 2011-11-11 2013-05-15 Almirall, S.A. New cyclohexylamine derivatives having beta2 adrenergic agonist and M3 muscarinic antagonist activities
EP2592077A1 (en) 2011-11-11 2013-05-15 Almirall, S.A. New cyclohexylamine derivatives having beta2 adrenergic agonist and M3 muscarinic antagonist activities
ES2728245T3 (es) * 2012-01-17 2019-10-23 Liconsa Laboratorios Sa Conjunto para administrar medicamentos, e inhalador monodosis para la administrar medicamentos en polvo seco que tiene dicho conjunto
EP2641900A1 (en) 2012-03-20 2013-09-25 Almirall, S.A. Novel polymorphic Crystal forms of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-(R)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one, heminapadisylate as agonist of the ß2 adrenergic receptor.
WO2014060431A1 (en) 2012-10-16 2014-04-24 Almirall, S.A. Pyrrolotriazinone derivatives as pi3k inhibitors
EP2738172A1 (en) 2012-11-28 2014-06-04 Almirall, S.A. New bicyclic compounds as crac channel modulators
AP2015008573A0 (en) 2012-12-18 2015-07-31 Almirall Sa New cyclohexyl and quinuclidinyl carbamate derivatives having beta 2 adrenergic agonist and M3 muscarinic antagonsit activity
US9398933B2 (en) 2012-12-27 2016-07-26 Holaira, Inc. Methods for improving drug efficacy including a combination of drug administration and nerve modulation
EP2848615A1 (en) 2013-07-03 2015-03-18 Almirall, S.A. New pyrazole derivatives as CRAC channel modulators
WO2015001561A1 (en) * 2013-07-03 2015-01-08 MEway Pharma LTD Metered dose inhaler and methods thereof
EP3154613B8 (en) * 2014-06-16 2020-08-19 Sanara Tech Ltd. A novel operated nebulizer and means thereof
MA41938A (fr) 2015-04-21 2018-02-28 Almirall Sa Dérivés hétérocycliques amino-substitués utilisés comme inhibiteurs des canaux sodiques
CN106619658B (zh) * 2016-12-28 2022-02-08 四川普锐特药业有限公司 一种医用气溶胶制剂及定量吸入气雾剂
TW201919682A (zh) 2017-08-08 2019-06-01 西班牙商阿爾米雷爾有限公司 活化Ｎｒｆ２路徑的新穎化合物
MX2020007997A (es) 2018-02-02 2020-12-03 Alexza Pharmaceuticals Inc Dispositivo electrico de aerosol de condensacion.
CN113244490A (zh) 2020-01-28 2021-08-13 奇斯药制品公司 包含缓冲药物制剂的加压定量吸入器
NZ790703A (en) 2020-02-20 2025-06-27 Chiesi Farm Spa Pressurised metered dose inhalers comprising a buffered pharmaceutical formulation

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1230339A (cs) * 1964-11-23 1971-04-28
WO1993011745A1 (en) * 1991-12-12 1993-06-24 Glaxo Group Limited Medicaments
EP0642992A2 (de) * 1993-08-27 1995-03-15 Ciba-Geigy Ag Aerosolbehälter mit FCK-freiem Treibgas und Dosierventil sowie seine Verwendung

Family Cites Families (108)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US327777A (en) 1885-10-06 Metal-punching machine
US2562118A (en) * 1950-02-09 1951-07-24 Du Pont Polytetrafluoroethylene coating compositions
NL208432A (cs) * 1954-09-20
US2968427A (en) * 1955-06-28 1961-01-17 Meshberg Philip Valve for aerosol container
GB878409A (en) * 1957-03-26 1961-09-27 United Drug And Chemical Compa Improvements in or relating to dispensing devices
US2886217A (en) * 1957-05-20 1959-05-12 Riker Laboratories Inc Dispensing device
US2892576A (en) * 1957-11-14 1959-06-30 Lawrence T Ward Metering button valve assembly
US2980301A (en) * 1958-09-02 1961-04-18 Riker Laboratories Inc Metering valve for aerosol container
GB864392A (en) * 1958-11-10 1961-04-06 Rexall Drug Company Ltd Improvements in or relating to dispensing devices for aerosols
US3506737A (en) * 1965-10-23 1970-04-14 Owens Illinois Inc Glass aerosol bottles and method for making same
US3360158A (en) * 1966-02-16 1967-12-26 American Can Co Container end wall construction
GB1200886A (en) * 1966-09-23 1970-08-05 Allen & Hanburys Ltd Phenylaminoethanol derivatives
GB1191700A (en) 1967-02-27 1970-05-13 Ekco Prod Inc Coated Metalware
FR1584784A (cs) * 1968-08-13 1970-01-02
US3904575A (en) 1969-07-21 1975-09-09 Daikin Ind Ltd Fluorocarbon polymer composition and production and use thereof
FR2082593A5 (en) 1970-03-20 1971-12-10 Oreal Aerosol can prodn
NO134730L (cs) 1971-07-19 1900-01-01
LU63737A1 (cs) 1971-08-17 1972-01-04
US4087026A (en) * 1971-09-15 1978-05-02 Petterson Tor H Barrier package
US3896602A (en) * 1971-09-15 1975-07-29 Tor H Petterson Method of manufacturing of a barrier package
FR2159593A5 (fr) * 1971-11-04 1973-06-22 Skm Sa Installation de peinture par pulverisation
US4143204A (en) * 1971-12-27 1979-03-06 E. I. Du Pont De Nemours And Company Articles coated with fluorocarbon resins
DE2227142A1 (de) 1972-06-03 1973-12-13 Pampus Kg Rohre und behaelter aus glasfaserverstaerktem kunststoff und einer auskleidung, zum beispiel aus ptfe
US3962171A (en) * 1973-03-02 1976-06-08 Mcgarry & Waters Composition for protecting surfaces
US3929537A (en) * 1973-07-19 1975-12-30 Austral Erwin Engineering Co Preparation of plastic-metal laminates
FR2267496A1 (en) * 1974-04-11 1975-11-07 Sidel Sa Method of sealing valve on aerosol container - uses internally ribbed sleeve over ribbed valve and sleeve
US4180609A (en) * 1975-07-11 1979-12-25 E. I. Du Pont De Nemours And Company Article coated with fluoropolymer finish with improved scratch resistance
JPS5327120A (en) 1976-08-26 1978-03-14 Union Carbide Corp Plasticssmade aerosol containers and method of producing the same
GB2003415A (en) 1977-09-02 1979-03-14 American Can Co Improvements relating to the manufacture of containers
US4125152A (en) * 1977-09-19 1978-11-14 Borg-Warner Corporation Scale resistant heat transfer surfaces and a method for their preparation
JPS5920547B2 (ja) * 1979-07-04 1984-05-14 東洋製罐株式会社 溶接缶
ZA807387B (en) * 1979-12-08 1981-11-25 Metal Box Co Ltd Containers
US4335121A (en) * 1980-02-15 1982-06-15 Glaxo Group Limited Androstane carbothioates
GB2077229B (en) * 1980-05-16 1983-08-03 Neotechnic Eng Ltd Valve assembly for a pressurized aerosoldispensing container
GB2105189B (en) 1981-07-24 1985-03-20 Fisons Plc Inhalation drugs
ZW6584A1 (en) 1983-04-18 1985-04-17 Glaxo Group Ltd Phenethanolamine derivatives
US4741934A (en) * 1985-04-19 1988-05-03 Nippon Steel Corporation Steel sheet for making cans, cans and a method making cans
NL8501767A (nl) * 1985-06-19 1987-01-16 Euro Technical Oilservices Bv Inrichting voor het behandelen van een verontreinigingen bevattende vloeistof.
EP0234774B1 (en) * 1986-02-27 1992-05-06 Nippon Kokan Kabushiki Kaisha Precoating metal sheet
JPS6312445A (ja) * 1986-06-24 1988-01-19 東洋製罐株式会社 イ−ジイオ−プン蓋付缶体及びその製法
US5536583A (en) * 1986-07-01 1996-07-16 Edlon Products, Inc. Polymer metal bonded composite and method of producing same
US4897439A (en) * 1986-07-01 1990-01-30 Edlon Products, Inc. Polymer-metal bonded composite and method of producing same
EP0260084B1 (en) * 1986-09-08 1992-12-30 Asia Can Company Limited Metal container and method of manufacturing the same
US4819834A (en) * 1986-09-09 1989-04-11 Minnesota Mining And Manufacturing Company Apparatus and methods for delivering a predetermined amount of a pressurized fluid
EP0327777A1 (fr) 1988-02-12 1989-08-16 S.A. DES ETABLISSEMENTS STAUBLI (France) Capteur de déplacement pour machines automatiques
GB2205297B (en) * 1987-06-05 1991-06-19 Lin Pac Mouldings A container assembly
JPS649158A (en) * 1987-06-22 1989-01-12 Takeuchi Press Metal container for aerosol and preparation thereof
WO1988010221A1 (fr) * 1987-06-26 1988-12-29 Werding Winfried J Dispositif pour le stockage et la distribution controlee de produits sous pression
DE8709978U1 (de) * 1987-07-21 1987-10-08 A. u. K. Müller GmbH & Co KG, 4000 Düsseldorf Elektromagnetventil, insbesondere Auslaufventil für Brühwasser
GB8724242D0 (en) * 1987-10-15 1987-11-18 Metal Box Plc Laminated metal sheet
GB8724243D0 (en) * 1987-10-15 1987-11-18 Metal Box Plc Laminates of polyolefin-based film
IT1223451B (it) * 1987-11-24 1990-09-19 Coster Tecnologie Speciali Spa Procedimento per ottenere fondelli metallici protetti per valvole per aerosol e simili
GB2214891A (en) 1988-02-05 1989-09-13 Fibrenyle Ltd Containers for pressurized material
JP2562343B2 (ja) * 1988-02-23 1996-12-11 北海製罐株式会社 エアゾール容器及びエアゾール製品
GB2216794B (en) * 1988-03-22 1991-11-20 Fisons Plc Pharmaceuticals compositions
IL89713A0 (en) * 1988-03-29 1989-09-28 Ciba Geigy Ag Novel alkanophenones
JPH0289633A (ja) * 1988-05-20 1990-03-29 Sumitomo Electric Ind Ltd フッ素樹脂被覆物
US4902318A (en) * 1988-05-25 1990-02-20 The United States Of America As Represented By The Administrator Of The Environmental Protection Agency Inlet apparatus for gas-aerosol sampling
US4961966A (en) * 1988-05-25 1990-10-09 The United States Of America As Represented By The Administrator Of The Environmental Protection Agency Fluorocarbon coating method
JPH0267374A (ja) * 1988-08-31 1990-03-07 Takeuchi Press Ind Co Ltd エアゾール缶容器
US5225183A (en) * 1988-12-06 1993-07-06 Riker Laboratories, Inc. Medicinal aerosol formulations
GB8828477D0 (en) * 1988-12-06 1989-01-05 Riker Laboratories Inc Medical aerosol formulations
GB8903629D0 (en) * 1989-02-17 1989-04-05 Metal Box Plc Metal/polymer laminates
US5176132A (en) * 1989-05-31 1993-01-05 Fisons Plc Medicament inhalation device and formulation
US5006383A (en) * 1989-06-28 1991-04-09 The Dow Chemical Company Polymeric blend and laminated structures prepared therefrom
FR2650219B1 (fr) * 1989-07-06 1991-10-04 Pechiney Rhenalu Procede d'obtention de materiaux multicouches aptes a etre transformes par emboutissage ou emboutissage-etirage en corps creux
FR2649359B1 (fr) * 1989-07-06 1993-02-12 Cebal Bande ou portion de bande pour emboutissage ou emboutissage-etirage, et son utilisation
JP2600387B2 (ja) * 1989-09-06 1997-04-16 東洋紡績株式会社 金属貼合せ用ポリエステルフィルム
US5208226A (en) * 1989-09-08 1993-05-04 Glaxo Group Limited Medicaments
US5270305A (en) * 1989-09-08 1993-12-14 Glaxo Group Limited Medicaments
US5345980A (en) 1989-09-21 1994-09-13 Glaxo Group Limited Method and apparatus an aerosol container
US5043191A (en) * 1990-02-27 1991-08-27 Miles Inc. Method of protecting hard surfaces
DE4009397A1 (de) * 1990-03-23 1991-09-26 Weidenhammer Packungen Dosenartige verpackung fuer fliessfaehige produkte
AU5798690A (en) * 1990-06-28 1991-08-22 Kabushiki Gaisha Tokai Vessel for aerosol
DE4023909A1 (de) * 1990-07-27 1992-01-30 Wild Rudolf Gmbh & Co Wiederverwendbarer behaelter aus kunststoff sowie seine herstellung und verwendung
GB9024365D0 (en) * 1990-11-09 1991-01-02 Glaxo Group Ltd Medicaments
DE69132258D1 (de) * 1990-11-14 2000-07-27 Titeflex Corp Laminate aus Fluorpolymer und Aluminium
AU652017B2 (en) * 1990-12-12 1994-08-11 E.I. Du Pont De Nemours And Company Non-stick coating system with PTFE of different melt viscosities for concentration gradient
EP0561981B1 (en) * 1990-12-12 1996-01-03 E.I. Du Pont De Nemours And Company Non-stick coating system with ptfe and pfa or fep for concentration gradient
US5168107A (en) * 1990-12-12 1992-12-01 E. I. Du Pont De Nemours And Company Non-stick coating system with PTFE of two low melt viscosities for concentration gradient
GB9027234D0 (en) * 1990-12-15 1991-02-06 Harris Pharma Ltd An inhalation device
EP0499142A3 (en) * 1991-02-09 1993-05-05 Hoechst Aktiengesellschaft Potentiation of the antireactive-antiasthmatic effect of inhaled loop diuretics by inhaled non steroidal anti-flammatory drugs
EP0504112A3 (en) * 1991-03-14 1993-04-21 Ciba-Geigy Ag Pharmaceutical aerosol formulations
RU2027448C1 (ru) 1991-04-25 1995-01-27 Государственное предприятие "ВЭЛТ" Ингалятор
AU663093B2 (en) * 1991-05-21 1995-09-28 Abbott Laboratories Aerosol inhalation device
RU2008939C1 (ru) 1991-06-10 1994-03-15 Вячеслав Николаевич Поздняков Физиотерапевтический ингалятор
RU2012362C1 (ru) 1991-06-24 1994-05-15 Юрий Алексеевич Волгин Ингалятор
DE4124730C3 (de) * 1991-07-25 2001-09-06 Ahc Oberflaechentechnik Gmbh Anodisierte Gegenstände aus Aluminium oder Magnesium mit in die Oxidschicht eingelagerten Fluorpolymeren und Verfahren zu deren Herstellung
US5736124A (en) * 1991-12-12 1998-04-07 Glaxo Group Limited Aerosol formulations containing P134a and particulate medicament
US5653962A (en) * 1991-12-12 1997-08-05 Glaxo Group Limited Aerosol formulations containing P134a and particulate medicaments
IL104068A (en) * 1991-12-12 1998-10-30 Glaxo Group Ltd Surfactant-free pharmaceutical aerosol formulation comprising 1,1,1,2-tetrafluoroethane or 1,1,1,2,3,3,3-heptafluoro-n- propane as propellant
US5202110A (en) * 1992-01-22 1993-04-13 Virginia Commonwealth University Formulations for delivery of beclomethasone diproprionate by metered dose inhalers containing no chlorofluorocarbon propellants
US5261538A (en) 1992-04-21 1993-11-16 Glaxo Inc. Aerosol testing method
EP1249712B1 (en) * 1992-06-25 2006-11-22 Denso Corporation Mobile object identification system
US5376359A (en) * 1992-07-07 1994-12-27 Glaxo, Inc. Method of stabilizing aerosol formulations
JP3303408B2 (ja) * 1992-07-09 2002-07-22 ダイキン工業株式会社 含フッ素樹脂複合微粒子
US5421492A (en) * 1993-11-02 1995-06-06 Glaxo Inc. Metered aerosol dispensing apparatus and method of use thereof
US5468798A (en) * 1994-02-18 1995-11-21 Whitford Corporation Basecoat for a coating system
US5508023A (en) * 1994-04-11 1996-04-16 The Center For Innovative Technology Pharmaceutically acceptable agents for solubilizing, wetting, emulsifying, or lubricating in metered dose inhaler formulations which use HFC-227 propellant
US5597433A (en) * 1994-05-27 1997-01-28 Panoramic, Inc. Method and apparatus for manufacturing plastic canisters
DK0820279T3 (da) * 1995-04-14 2002-10-07 Smithkline Beecham Corp Dosisudmålende inhalator til Albuterol
EE9700372A (et) * 1995-04-14 1998-06-15 Glaxo Wellcome Inc. Beklometasoondipropionaadi doseeriv inhalaator
PL180901B1 (pl) * 1995-04-14 2001-04-30 Glaxo Wellcome Inc Inhalator z dozymetrem
EP1769819A3 (en) * 1995-04-14 2013-05-22 GlaxoSmithKline LLC Metered dose inhaler for fluticasone propionate
US5674592A (en) * 1995-05-04 1997-10-07 Minnesota Mining And Manufacturing Company Functionalized nanostructured films
US5891420A (en) * 1997-04-21 1999-04-06 Aeropharm Technology Limited Environmentally safe triancinolone acetonide aerosol formulations for oral inhalation
GB2332372B (en) * 1997-12-08 2002-08-14 Minnesota Mining & Mfg Pharmaceutical aerosol compositions
JP3199699B2 (ja) 1999-04-14 2001-08-20 核燃料サイクル開発機構 弁座面の平坦度測定装置

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1230339A (cs) * 1964-11-23 1971-04-28
WO1993011745A1 (en) * 1991-12-12 1993-06-24 Glaxo Group Limited Medicaments
EP0642992A2 (de) * 1993-08-27 1995-03-15 Ciba-Geigy Ag Aerosolbehälter mit FCK-freiem Treibgas und Dosierventil sowie seine Verwendung

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
K. BATZAR: "Principles of Adhesion of fluoropolymer coatings to substrates", ADV. ORG. COATING SCI. TECH. SER., vol. 13, 1991, pages 463 - 471, XP002471095 *
ULLMANN'S ENCYCLOPEDIA OF INDUSTRIAL CHEMISTRY, vol. A18, 1991, pages 380 - 382, XP002471094 *

Also Published As

Publication number Publication date
EP1547636A1 (en) 2005-06-29
CA2217954A1 (en) 1996-10-17
ATE297773T1 (de) 2005-07-15
MX9707864A (es) 1997-11-29
DK0820323T3 (da) 2003-11-24
HUP9802391A2 (hu) 1999-02-01
EA199700233A1 (ru) 1998-02-26
RO119116B1 (ro) 2004-04-30
KR19980703848A (ko) 1998-12-05
BG102022A (bg) 1998-07-31
AU5481196A (en) 1996-10-30
CN1142798C (zh) 2004-03-24
HUP9802391A3 (en) 2000-06-28
NO974736L (no) 1997-12-11
SK284447B6 (sk) 2005-04-01
PT820323E (pt) 2004-03-31
DE69630111T2 (de) 2004-07-22
EP1366777B1 (en) 2005-06-15
SK138997A3 (en) 1998-04-08
CA2217954C (en) 2005-02-15
US6524555B1 (en) 2003-02-25
JPH11509434A (ja) 1999-08-24
ATE250439T1 (de) 2003-10-15
DE69634865D1 (de) 2005-07-21
EP0820323A1 (en) 1998-01-28
EP1366777A1 (en) 2003-12-03
NO974736D0 (no) 1997-10-13
EA000892B1 (ru) 2000-06-26
WO1996032150A1 (en) 1996-10-17
DE69630111D1 (de) 2003-10-30
ES2206572T3 (es) 2004-05-16
HK1009405A1 (en) 1999-09-17
AP9701113A0 (en) 1997-10-31
CZ296209B6 (cs) 2006-02-15
EP1908488A2 (en) 2008-04-09
EE04005B1 (et) 2003-04-15
US6143277A (en) 2000-11-07
CY2479B1 (en) 2005-06-03
PL322771A1 (en) 1998-02-16
UA54386C2 (uk) 2003-03-17
IS4579A (is) 1997-09-06
TR199701169T1 (xx) 1998-03-21
CZ326097A3 (cs) 1998-02-18
KR100403899B1 (ko) 2004-03-20
AP979A (en) 2001-06-28
AU718263B2 (en) 2000-04-13
EP0820323B1 (en) 2003-09-24
EE9700374A (et) 1998-06-15
PL180901B1 (pl) 2001-04-30
BR9604977A (pt) 1998-06-09
CN1186447A (zh) 1998-07-01
OA10626A (en) 2001-04-24
BG64117B1 (bg) 2004-01-30
NZ306280A (en) 1999-07-29

Similar Documents

Publication Publication Date Title
EP1908488A3 (en) Metered dose inhaler for salmeterol
EP1870122A3 (en) Metered dose inhaler
EP1769819A3 (en) Metered dose inhaler for fluticasone propionate
BG102023A (bg) Дозиращ инхалатор за беклометазондипропионат
EP0667148A4 (en) PERORAL PHARMACEUTICAL PREPARATION WITH RELEASE IN THE LOWER DIGESTIVE TRACT.
EP1208864A3 (en) Improvements in drug delivery devices
WO2002072033A3 (en) Chronotherapeutic dosage forms containing glucocorticosteroid
WO2001062227A3 (en) Anticholinergic drug formulations for treatment of chronic obstr uctive pulmonary disease
IT1271122B (it) Composizioni farmaceutiche a rilascio controllato osmotico e per diffusione del farmaco e procedimento per la loro preparazione
HUT67480A (en) Pressurised aerosol inhalation compositions
CA2101245A1 (en) Dosage forms comprising polymers comprising different molecular weights
CA2354561A1 (en) Spacer device for inhaler
CA2362499A1 (en) Combinations of formoterol and mometasone furoate for asthma
CA2289088A1 (en) Microparticles useful as ultrasonic contrast agents and for delivery of drugs into the bloodstream
ATE271377T1 (de) Arzneimittelform mit zwei überzugs-schichten
AU3268789A (en) Osmotic continuous dispensing oral delivery system containing pharmaceutically acceptable active agent having improved core membrane adhesion properties
AU5655696A (en) Pharmaceutical composition containing acetylcysteine, carboc ysteine or erdosteine in combination with a beta 2 agonist a nd an expectorant for the treatment of respiratory tract dis orders
AU2001289126A1 (en) Metered dose inhaler can coated two or more times with fluorocarbon polymers
DE69222295D1 (de) Pulverförmige pharmazeutische Zusammensetzung
CA2447517A1 (en) Metered dose inhaler for fluticasone propionate
CA2367013A1 (en) Metered dose inhaler for fluticasone propionate
CA2209673A1 (en) Solid medicament form with active agent distributed in polymer material
EP0761209A3 (en) Controlled release formulations of ranitidine
WO1998005362A3 (en) Protein-containing polymer composition for oral administration
TH61465B (th) องค์ประกอบโดสสำหรับให้ทางปากที่ปลดปล่อยได้นานขึ้น

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

PUAL Search report despatched

Free format text: ORIGINAL CODE: 0009013

17P Request for examination filed

Effective date: 20071220

AC Divisional application: reference to earlier application

Ref document number: 0820323

Country of ref document: EP

Kind code of ref document: P

Ref document number: 1366777

Country of ref document: EP

Kind code of ref document: P

Ref document number: 1547636

Country of ref document: EP

Kind code of ref document: P

AK Designated contracting states

Kind code of ref document: A2

Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

AX Request for extension of the european patent

Extension state: AL LT LV SI

AK Designated contracting states

Kind code of ref document: A3

Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

AX Request for extension of the european patent

Extension state: AL LT LV SI

17Q First examination report despatched

Effective date: 20081104

AKX Designation fees paid

Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

AXX Extension fees paid

Extension state: AL

Payment date: 20071220

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: GLAXOSMITHKLINE LLC

TPAC Observations filed by third parties

Free format text: ORIGINAL CODE: EPIDOSNTIPA

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION HAS BEEN REFUSED

18R Application refused

Effective date: 20130201