EP0679439B1 - Pipette de distribution à répétition - Google Patents

Pipette de distribution à répétition Download PDF

Info

Publication number
EP0679439B1
EP0679439B1 EP95104248A EP95104248A EP0679439B1 EP 0679439 B1 EP0679439 B1 EP 0679439B1 EP 95104248 A EP95104248 A EP 95104248A EP 95104248 A EP95104248 A EP 95104248A EP 0679439 B1 EP0679439 B1 EP 0679439B1
Authority
EP
European Patent Office
Prior art keywords
pawl
receiving body
withholding
rack
displacing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP95104248A
Other languages
German (de)
English (en)
Other versions
EP0679439A1 (fr
Inventor
Herbert Belgardt
Klaus Ing. Schürbrock (grad.)
Rolf-Günter Meyer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eppendorf SE
Original Assignee
Eppendorf Netheler Hinz GmbH
Eppendorf Geraetebau Netheler and Hinz GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eppendorf Netheler Hinz GmbH, Eppendorf Geraetebau Netheler and Hinz GmbH filed Critical Eppendorf Netheler Hinz GmbH
Publication of EP0679439A1 publication Critical patent/EP0679439A1/fr
Application granted granted Critical
Publication of EP0679439B1 publication Critical patent/EP0679439B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Images

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • B01L3/0234—Repeating pipettes, i.e. for dispensing multiple doses from a single charge

Definitions

  • the invention relates to a repeater pipette according to the Preamble of claim 1.
  • a repeating pipette of the above type is known from DE 29 26 691 C2 known.
  • the syringe holder is one U-shaped groove in a pipette housing, into which a syringe flange inserted through a side opening in the housing can be.
  • the syringe flange is in the holder loaded by a compression spring in the direction of the discharge opening.
  • the syringe plunger has a cylindrical actuation section, by means of a clamping device in the receiving body is fixable.
  • the piston return mechanism is designed as a lever of the receiving body, the protrudes through a side housing slot.
  • the piston feed device is a rack and pawl device the rack connected to the receiving body and the Pawl pivotable on a reciprocating drive lever is stored.
  • the increment setting device is coupled with a rotary knob Tongue executed, the teeth depending on the position of the Rotary knob more or less covered. By setting the knob is the section of the pawl movement adjustable by engaging the rack and takes the piston. This is what is delivered by the syringe Liquid volume adjustable using the rotary knob.
  • the syringe sits with a certain amount in its recordings Game.
  • the sliding devices are with one Game affected.
  • the piston after the Pull out with constant step size setting in a first advance by a distance other than moved in the following steps.
  • the first step The amount of liquid ejected thus gives way considerably from the liquid discharge every subsequent one Step off. Therefore, for an exact dosage one discards in practice the volume of liquid expelled during the first step. As a result, sample liquid is lost. You can counter this by being proportionate small first step size set and for the following ones Steps changed the width to the required value becomes. However, this requires increased handling effort and is prone to errors.
  • the object of the invention is a repeater pipette of the type mentioned is available to provide that with little handling accurate dosing with reduced sample fluid loss enables.
  • a repeating pipette there is a constant step device provided that regardless of the Setting the step size using the step size setting device the width of the first step the retraction of the receiving body to a constant Value.
  • the Pistons are therefore independent of the setting of the dispensing volumes a constant volume of liquid in the subsequent steps out.
  • the breadth of the first step can be dimensioned so that when reversing the direction of piston movement occurring game effects just for sure overcome and the smallest possible volume of liquid is expelled.
  • the first step size is 2 mm. Due to the equalization achieved in the following steps a very precise liquid dosage according to the set increment reached. Minimal fluid release during the first step leads to a maximum fluid volume for the remaining steps. As a result, a maximum number Residual steps achieved by the step size setting depends.
  • a repeater pipette enables for the first time an exact dosage and a maximum Number of dosing steps without special handling required by the user.
  • the piston advancing device is preferably a rack-and-pawl device according to DE 29 26 691 C1.
  • a rack with tooth-like can generally be used as a rack Protrusions are used including a threaded rod or a rod with circumferential grooves.
  • Incremental adjustment device comes according to the above Document preferably a slidable along the rack Barrier element, for example in the form of a tongue to use, which is the pawl engagement in the rack limited.
  • the constant step device is a further holding element have, which from a holding position in a release position is movable. In the holding position Pawl engagement prevented and enabled in the release position. The movement of the holding element is determined by the Controlled movement of the receiving body.
  • the further blocking element is controlled in the blocking position.
  • advancing the receiving body controls the blocking element in the release position.
  • the one in the holding position stops further holding element first the pawl of an intervention in the rack.
  • One with the receiving body connected stop element protrudes into the range of motion of pawl and / or the actuator with the receptacle completely pushed back in and is in the end section of the first step of the actuator and / or the pawl is pushed in the feed direction.
  • the stop element takes the receiving body in the direction of advance with, whereby the further holding element in Release position is controlled. This will in turn for the rest of the first step and / or further steps a ratchet engagement in the rack enables.
  • the further holding element is preferably an L-shaped one Lever.
  • a first leg of the lever is pivotally mounted and acts with an end support surface of the Receiving body together.
  • the second leg has the Holding surface of the holding element.
  • the first leg is preferably near its free end pivoted and the holding surface on the inside of the second leg.
  • the jack is then Can be placed on the inside of the two legs to save space.
  • the first leg at a distance of his pivot bearing be provided with a cam that cooperates with a support surface of the receiving body.
  • the stop element can be in a holding position over the further retaining element protruding projection of the rack be.
  • the stop element can also be one of the receiving body protruding and in the range of motion of the actuator protruding pin.
  • the Piston feed device slips after pushing back then the latch over the other holding element and that Actuator meets the pin.
  • the end area its movement pushes the actuating element onto the receiving body by means of the pin in the feed direction, whereby again the further holding element in the release position controlled and pawl engagement for further advancement is made possible.
  • the receiving body preferably controls the further holding element so that the pawl already during the first advance step into a certain one Tooth of the rack falls. Then the first step leads to a reproducible starting position of the Syringe plunger and for each set increment the number of possible dosages known.
  • pawl intervention in a particular tooth can be a recess of the Barrier element in the end area of the pawl movement in the direction of displacement be provided.
  • the actuator when moving in the direction of advance initially meets the Pen, and after further movement in the same direction the pawl engages in a tooth of the rack in the recess of the holding element.
  • one the only tooth exposed through the recess Stop element for advancing the receiving body be.
  • the housing 1 has a housing 1, the a central section 2 designed as a handle, a Foot section 3 and a head section 4 with a finger engagement recess 5 has.
  • the foot section 3 is one Syringe holder 6 arranged for a syringe flange, the one to the right (in the drawing) of the housing 1 open groove is designed with a U-cross section. Further is the foot end 3 with an end opening 7 provided for the syringe body.
  • the middle section 2 has a guide 8 in the inside designed as a sliding block receiving body 9 for the actuating end the syringe plunger is guided.
  • the receiving body 9 has a - not shown - clamping device with which the inserted operating end in the receiving body 9 can be determined.
  • the receiving body 9 has a push-back lever 10, which protrudes from a slot 11 in the right side of the housing.
  • the receiving body 9 bears on one facing away from the receptacle 6 front face 12 plan a rack 13 that through the middle section 2 to the head section 4 of the housing 1 extends.
  • the rack 13 has the right side a sawtooth-shaped toothing 14, the steeper Flank facing the head portion 4.
  • a leg spring 20 Between a pin 19 of the operating lever 17th and the housing inner wall acts a leg spring 20, the biases the operating lever 17 toward the housing head 4.
  • a pawl 22 which 1 with its end of engagement in the toothing 14 takes hold.
  • the pawl 22 is by means of one on it and the actuating lever 17 supported additional leg spring 23 biased towards the rack 13.
  • a holding element in the form of a tongue 24 arranged.
  • the tongue 24 covers part of the toothing 14 and is slidable along this. For that them near their facing away from the rack 13 End a pin 25 which in a guide curve 26 one engages in the housing head 4 mounted rotary knob 27.
  • the Location of the tongue 24 in the housing and the extent of its coverage with the toothing 14 is by adjusting the knob 27 changeable.
  • the first leg 30 has on the storage opposite end on the receiving body 9 facing Side a cam 31.
  • a second leg 32 forms a holding surface with a side facing the pawl 22 33.
  • the pawl 22 is on the inside of the two legs 30, 32 arranged.
  • a supported on the housing side Spring can bias lever 29 counterclockwise.
  • the rack 13 is on its receiving body side End with a paragraph 34, which over the teeth 14 protrude.
  • a syringe is with her from the right side of the housing Flange into the syringe holder 6, with your body in the Through opening 7 and its actuating end in the receiving body 9 introduced.
  • the recording 6 it is from a - not shown - leaf spring to their delivery end biased towards and clamped in the receiving body 9.
  • the syringe can be both empty and filled, with fully inserted or pulled out Syringe plunger can be used. If it is used filled, is previously the receiving body 9 by means of the push-back lever 10 in the R direction. An unfilled used syringe can when pushing back the push lever 10 Aspirate liquid.
  • the repeater pipette is a piston drawn from the syringe ready for liquid delivery.
  • 2 shows the receiving body 9 in this position in which it with its end face 12 serving as a support surface against presses the cam 31 of the lever 29.
  • This is the lever 29 pivoted slightly clockwise so that its second leg 32 aligned parallel to the rack 13 and with its holding surface 33 on the right over the Teeth 14 stands out.
  • the operating arm 17 carries the pawl 22 the end of the engagement surface 33 along without there is a pawl engagement in the teeth 14.
  • the receiving body 9 and the syringe plunger not advanced towards V.
  • the pawl 22 has reached paragraph 34.
  • the 4 to 7 is also in the embodiment L-shaped lever 29 provided on the right side the rack 13 with a first leg 30 on one axis 28 fixed to the housing.
  • the first leg 30 carries a parallel to it at a distance from the axis 28 Cam 31, according to FIG. 4, on a rack 13 parallel projection 36 of the end face 12 of the Receiving body 9 rests.
  • the second leg 32 of the lever 29 has adjacent to the first leg 30 has a recess 37 which extends over approximately extends half its length. Adjacent to it, the Leg 32 a holding surface facing the pawl 22 33.
  • the lever 29 is from the pawl 22 and one on the housing 1 supported leg spring 39 in a counterclockwise direction acted upon.
  • the receiving body 9 carries a pin 38 which is in the Movement range of the operating lever 17 protrudes.
  • This repeater pipette works as follows:
  • Fig. 6 it is shown that the operating lever 17 the Pin 38 and the receiving body 9 upon further actuation advances in the direction of advance V.
  • the spring-loaded lever 29 pivoted counterclockwise and releases the teeth 14.
  • the jack 22 engages exactly in the first tooth of toothing 14.
  • Fig. 7 shows that the rack 13 and connected receptacle 9 exactly in one by Impact of the pawl 22 against the stop fixed to the housing 35 certain position is advanced.
  • the pawl 22 is out on a larger arc around axis 15 than the contact area of the actuating lever pressing on the pin 38 17.
  • the operating lever lies 17 at the end of its first operation no longer on the Pin 38 on and the feed path of the receiving body 9th is determined exclusively by the jack intervention.
  • the actuating lever is used for a subsequent liquid metering 17 pivoted back counterclockwise.
  • the pawl 22 is first prevented from engaging by the tongue 24.
  • the rack 13 in Direction V engages them and pushes the rack 13 in Direction V.
  • the quantities of liquid dispensed depend thus solely on the setting of the tongue 24.
  • FIGS. 8 to 14 has in contrast to that 4 a further in the direction of the second leg 32 of the lever 29 extends recess 37.
  • the recess 37 there are four teeth adjacent to the holding surface 33 Teeth 14 free.

Landscapes

  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Steroid Compounds (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Liquid Developers In Electrophotography (AREA)

Claims (10)

  1. Pipette à répétition comportant un réceptacle de seringue (6) pour la partie de fixation d'une seringue, un corps de réceptacle (9) muni d'un réceptacle de piston pour la partie d'actionnement d'un piston de seringue, un dispositif de rappel (10) du piston pour faire coulisser en arrière le corps de réceptacle en l'éloignant du réceptacle de seringue, un dispositif d'avancement du piston (13, 17, 22) pour faire coulisser vers l'avant le corps de réceptacle en direction du réceptacle avec des pas correspondant aux volumes de liquide à éjecter de la seringue, et un dispositif de réglage (24 - 26) de la longueur de pas, pour régler la longueur du pas du corps de réceptacle au moyen d'un élément de réglage (27), caractérisé en ce qu'un dispositif à pas constant (29) fixe la longueur du premier pas à une valeur constante, indépendamment du réglage de l'élément de réglage (27) pour les longueurs des pas suivants.
  2. Pipette à répétition suivant la revendication 1, caractérisée en ce que le dispositif d'avancement du piston présente une tige dentée (13), liée au corps de réceptacle (9), et un cliquet (22), monté pivotant sur un élément d'actionnement (17) et qui, lors d'un déplacement de l'élément d'actionnement dans la direction d'avancement (V), vient s'engrainer avec la denture (14) de la tige dentée (13) et entraíne celle-ci, et, lors d'un déplacement dans la direction du recul (R), se libère de l'engagement avec la tige dentée (13), et en ce que le dispositif de réglage de la dimension de pas présente un élément d'arrêt (24) pouvant coulisser sur la tige dentée (13) au moyen de l'élément de réglage (27) pour limiter l'engrainement du cliquet (22) dans la denture, le dispositif à pas constant présentant un autre élément d'arrêt (29) qui est mobile entre une position d'arrêt empêchant l'engagement dans la tige dentée (13) et une position de libération permettant l'engagement du cliquet, son mouvement pour venir en position d'arrêt étant commandé par le coulissement en arrière, et son mouvement pour venir en position de libération étant commandé par le coulissement en avant du corps de réceptacle (9), et le corps de réceptacle (9) étant relié à un élément de butée (34, 38) qui, lorsque le corps de réceptacle (9) a complètement coulissé vers l'arrière, s' engraine dans la zone de mouvement du cliquet (22) et/ou de l'élément d'actionnement (17) et est poussé par l'élément d'actionnement et/ou par le cliquet dans la partie finale de leur mouvement en entraínant le corps de réceptacle dans la direction d'avancement (V).
  3. Pipette à répétition suivant la revendication 2, caractérisée en ce que l'autre élément d'arrêt est un levier (29) qui est monté pivotant sur un premier bras (30) et dont le deuxième bras (32) présente une surface d'arrêt (33) pour le cliquet (22), et en ce que le corps de réceptacle (9) présente une surface d'appui (12, 36) qui, lors du coulissement vers l'arrière, pousse contre le premier bras (30) et fait pivoter le deuxième bras (32) dans la position d'arrêt.
  4. Pipette à répétition suivant la revendication 3, caractérisée en ce que le premier bras (30) est monté pivotant au voisinage de son extrémité libre et que la surface d'arrêt (33) est réalisée sur le côté intérieur du deuxième bras (32).
  5. Pipette à répétition suivant la revendication 3 ou la revendication 4, caractérisée en ce que le premier bras (30) présente, à une certaine distance de son palier de pivotement (28), une came (31) pour l'appui sur une surface d'appui (12, 36) du corps de réceptacle (9).
  6. Pipette à répétition suivant l'une des revendication 2 à 5, caractérisée en ce que l'élément de butée est une saillie (34) de la tige dentée (13), dépassant, en position d'arrêt, de l'élément d'arrêt (29).
  7. Pipette à répétition suivant l'une des revendication 2 à 6, caractérisée en ce que l'élément de butée est une tige (38) située en avant du corps de réceptacle (9) et dépassant dans la zone de déplacement de l'élément d'actionnement (17).
  8. Pipette à répétition suivant l'une des revendication 2 à 7, caractérisée en ce que l'autre élément d'arrêt (29) présente, dans la direction d'avancement (V), dans la zone de la fin du déplacement du cliquet (22), un évidement (37) permettant l'engagement du cliquet dans la denture (14).
  9. Pipette à répétition suivant la revendication 7 et la revendication 8, caractérisée en ce que l'élément d'actionnement (17), lors du mouvement dans la direction d'avancement (V), rencontre la tige (38), et, lorsque le mouvement se poursuit dans la même direction, le cliquet (22) s'engraine dans la denture (14), à l'intérieur de l'évidement (37) de l'autre élément d'arrêt (29)
  10. Pipette à répétition suivant la revendication 8, caractérisée en ce que l'autre élément d'arrêt (29) présente un évidement (37) permettant un engagement du cliquet dans plusieurs dents de la denture (14), l'engagement du cliquet dans la première dent dans le sens d'avancement (V), provoquant un coulissement de la longueur constante, vers l'avant, du corps de réceptacle (9), et en ce que, lorsque cet engagement du cliquet est empêché par l'élément d'arrêt déplaçable (24), l'élément d'actionnement (17) rencontre la tige (38) et fait coulisser vers l'avant le corps de réceptacle (9) jusqu'à l'engagement du cliquet dans une dent accessible située à côté de l'élément d'arrêt déplaçable.
EP95104248A 1994-04-27 1995-03-23 Pipette de distribution à répétition Expired - Lifetime EP0679439B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4414760A DE4414760C1 (de) 1994-04-27 1994-04-27 Repetierpipette
DE4414760 1994-04-27

Publications (2)

Publication Number Publication Date
EP0679439A1 EP0679439A1 (fr) 1995-11-02
EP0679439B1 true EP0679439B1 (fr) 1998-03-04

Family

ID=6516609

Family Applications (1)

Application Number Title Priority Date Filing Date
EP95104248A Expired - Lifetime EP0679439B1 (fr) 1994-04-27 1995-03-23 Pipette de distribution à répétition

Country Status (8)

Country Link
US (1) US5591408A (fr)
EP (1) EP0679439B1 (fr)
JP (1) JP3673927B2 (fr)
AT (1) ATE163572T1 (fr)
CA (1) CA2147345C (fr)
DE (2) DE4414760C1 (fr)
ES (1) ES2115284T3 (fr)
FI (1) FI116203B (fr)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102010035891A1 (de) 2010-08-30 2012-03-01 Eppendorf Ag Spritze für den Gebrauch mit einer Dosiervorrichtung
EP2656916A1 (fr) 2012-04-23 2013-10-30 Eppendorf AG Procédé de dosage de liquide au moyen d'une pipette et d'une seringue ainsi que la pipette destinée à actionner une seringue pour le dosage de liquides
EP2656915A1 (fr) 2012-04-23 2013-10-30 Eppendorf AG Pipette destinée à actionner une seringue
DE102012011938A1 (de) 2012-06-18 2013-12-19 Eppendorf Ag Pipette zum Betätigen einer Spritze
EP2783753A1 (fr) 2013-03-28 2014-10-01 Eppendorf Ag Distributeur destiné à actionner une seringue
DE102014109345A1 (de) 2014-07-04 2016-01-07 Eppendorf Ag Pipette zum Betätigen einer Spritze
EP3335795A1 (fr) 2016-12-16 2018-06-20 Eppendorf AG Procédé de dosage de liquide au moyen d'une pipette et d'une seringue et pipette destinée à actionner une seringue pour le dosage de liquides

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09128717A (ja) * 1995-10-30 1997-05-16 Fujitsu Ltd 薄膜磁気ヘッドとその製造方法及び磁気記録装置
JP2838070B2 (ja) * 1996-03-07 1998-12-16 株式会社ニチリョー 反復式ピペット
JP4148894B2 (ja) 2001-10-16 2008-09-10 マトリックス・テクノロジイズ・コーポレーション 手持ち式ピペット
US7284454B2 (en) * 2004-05-27 2007-10-23 Matrix Technologies Corporation Hand held pipette
US20060027033A1 (en) * 2002-10-16 2006-02-09 Richard Cote Hand-held pipette employing voice recognition control
US7047056B2 (en) * 2003-06-25 2006-05-16 Nellcor Puritan Bennett Incorporated Hat-based oximeter sensor
US7396512B2 (en) * 2003-11-04 2008-07-08 Drummond Scientific Company Automatic precision non-contact open-loop fluid dispensing
US7381371B2 (en) * 2004-01-16 2008-06-03 Heathrow Scientific Llc Pipette device with pivotable nozzle assembly
US20080199361A1 (en) * 2007-02-16 2008-08-21 Francis Gomes Hand-held pipetting device
DE102007042115B4 (de) 2007-09-05 2010-12-02 Eppendorf Ag Pipette
DE102009034897A1 (de) * 2009-07-27 2011-02-03 Eppendorf Ag Spritze, Spritzenfamilie und Dosiervorrichtung
DE202010010942U1 (de) * 2010-08-03 2011-11-08 Brand Gmbh + Co Kg Pipette für ein Pipettensystem mit Pipette und Spritze
US9579644B2 (en) 2012-04-23 2017-02-28 Eppendorf Ag Pipette for operating a syringe
US9289762B2 (en) 2012-04-23 2016-03-22 Eppendorf Ag Method for dosing a liquid using a pipette and a syringe, and pipette for operating a syringe for dosing a liquid
US8845578B2 (en) 2013-02-28 2014-09-30 Medtronic Xomed, Inc. Biomaterial delivery device
US8920364B2 (en) 2013-02-28 2014-12-30 Medtronic Xomed, Inc. Biomaterial delivery device
WO2014204587A1 (fr) * 2013-06-17 2014-12-24 Waters Technologies Corporation Micropipette d'aliquotage de petits volumes de liquide
FR3026659B1 (fr) * 2014-10-03 2016-12-23 Gilson Sas Pipette de prelevement a bouton de commande ergonomique
JP6720082B2 (ja) * 2014-11-17 2020-07-08 株式会社アイカムス・ラボ 分注装置、及び分注システム

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2768769A (en) * 1954-02-19 1956-10-30 T W Snow Construction Co Locomotive sanding station
DE2926691C2 (de) * 1979-07-02 1983-05-26 Eppendorf Gerätebau Netheler + Hinz GmbH, 2000 Hamburg Repetierpipette
DE2549477C3 (de) * 1975-11-05 1982-01-07 Eppendorf Gerätebau Netheler + Hinz GmbH, 2000 Hamburg Pipettiervorrichtung
US4099548A (en) * 1976-08-25 1978-07-11 Oxford Laboratories Inc. Hand-held pipette for repetitively dispensing precise volumes of liquid
DE3204178C2 (de) * 1982-02-06 1986-03-20 Eppendorf Gerätebau Netheler + Hinz GmbH, 2000 Hamburg Pipettiervorrichtung
US4467942A (en) * 1982-04-29 1984-08-28 Yuuji Oshikubo Repeating dispenser
EP0109913A3 (fr) * 1982-11-03 1984-09-12 Micro-Mega Seringue dentaire pour injections intra-ligamentaires
US4671123A (en) * 1984-02-16 1987-06-09 Rainin Instrument Co., Inc. Methods and apparatus for pipetting and/or titrating liquids using a hand held self-contained automated pipette
FI921648A0 (fi) * 1992-04-13 1992-04-13 Labsystems Oy Stegpipett.
US5323931A (en) * 1993-02-08 1994-06-28 Prince Castle Inc. Dispenser for extrudable material including dispensing from collapsible containers

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102010035891A1 (de) 2010-08-30 2012-03-01 Eppendorf Ag Spritze für den Gebrauch mit einer Dosiervorrichtung
EP2425896A1 (fr) 2010-08-30 2012-03-07 Eppendorf AG Seringue pour l'utilisation à l'aide d'un dispositif de dosage
US8839685B2 (en) 2010-08-30 2014-09-23 Eppendorf Ag Syringe for use with a dosing device
EP2656916A1 (fr) 2012-04-23 2013-10-30 Eppendorf AG Procédé de dosage de liquide au moyen d'une pipette et d'une seringue ainsi que la pipette destinée à actionner une seringue pour le dosage de liquides
EP2656915A1 (fr) 2012-04-23 2013-10-30 Eppendorf AG Pipette destinée à actionner une seringue
DE102012011938A1 (de) 2012-06-18 2013-12-19 Eppendorf Ag Pipette zum Betätigen einer Spritze
EP2676730A1 (fr) 2012-06-18 2013-12-25 Eppendorf Ag Pipette destinée à actionner une seringue
EP2783753A1 (fr) 2013-03-28 2014-10-01 Eppendorf Ag Distributeur destiné à actionner une seringue
DE102014109345A1 (de) 2014-07-04 2016-01-07 Eppendorf Ag Pipette zum Betätigen einer Spritze
WO2016001010A1 (fr) 2014-07-04 2016-01-07 Eppendorf Ag Pipette servant à faire fonctionner une seringue
US10507463B2 (en) 2014-07-04 2019-12-17 Eppendorf Ag Pipette for activating a syringe
EP3335795A1 (fr) 2016-12-16 2018-06-20 Eppendorf AG Procédé de dosage de liquide au moyen d'une pipette et d'une seringue et pipette destinée à actionner une seringue pour le dosage de liquides

Also Published As

Publication number Publication date
ATE163572T1 (de) 1998-03-15
CA2147345A1 (fr) 1995-10-28
CA2147345C (fr) 2001-12-25
JP3673927B2 (ja) 2005-07-20
FI951978A0 (fi) 1995-04-26
JPH07294305A (ja) 1995-11-10
DE4414760C1 (de) 1995-08-24
DE59501518D1 (de) 1998-04-09
US5591408A (en) 1997-01-07
ES2115284T3 (es) 1998-06-16
EP0679439A1 (fr) 1995-11-02
FI951978A (fi) 1995-10-28
FI116203B (fi) 2005-10-14

Similar Documents

Publication Publication Date Title
EP0679439B1 (fr) Pipette de distribution à répétition
DE69420511T2 (de) Verbesserte injektionsvorrichtungen
EP1084763B1 (fr) Distributeur, notamment pour pulvériser un produit fluide contenu dans un réservoir
DE68912814T2 (de) Spritzen.
EP0679440B1 (fr) Pipette de distribution à répétition
DE69621133T2 (de) Automatischer kolbenstangenrückzug
DE2340379A1 (de) Geraet zur dosierenden abgabe von paste oder vergleichbaren massen
WO2010099850A1 (fr) Dispositif d'injection à réglage de volume d'injection
DE2926691A1 (de) Repetierpipette
DE10018924C2 (de) Vorrichtung zur dosierten Verabreichung eines injizierbaren Produkts
EP1981570B1 (fr) Poussoir pourvu d'un élément de couplage
EP3102257B1 (fr) Dispositif d'injection
DE10020591B4 (de) Ausgabevorrichtung für viskoses Dentalmaterial
DE9415847U1 (de) Repetierpipette
DE3213933A1 (de) Vorrichtung zum anbringen von etikettenhaltern
DE4437716C2 (de) Repetierpipette
DE19618544C1 (de) Applikator
DE10259777B4 (de) Brennkraftbetriebenes Arbeitsgerät, insbesondere Setzgerät für Befestigungselemente
DE1791094C3 (de) Vorrichtung zur selbsttätigen Durchführung einer Mehrzahl von dosierten Injektionen
DE4425763A1 (de) Vorrichtung zum Vorschub eines Kolbenverschiebeorgans
EP1019194B1 (fr) Pipette a repetition pourvue d'un dispositif d'actionnement hydraulique
DE2649760A1 (de) Vorrichtung zum ablegen von testtabletten auf kulturen
DE10058283A1 (de) Kartuschensystem
DE3306524A1 (de) Dosiervorrichtung
DE4106196A1 (de) Implantationsgeraet

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE CH DE ES FR GB IT LI LU NL SE

17P Request for examination filed

Effective date: 19951106

GRAG Despatch of communication of intention to grant

Free format text: ORIGINAL CODE: EPIDOS AGRA

17Q First examination report despatched

Effective date: 19970610

GRAG Despatch of communication of intention to grant

Free format text: ORIGINAL CODE: EPIDOS AGRA

GRAH Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOS IGRA

GRAH Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOS IGRA

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): AT BE CH DE ES FR GB IT LI LU NL SE

REF Corresponds to:

Ref document number: 163572

Country of ref document: AT

Date of ref document: 19980315

Kind code of ref document: T

REG Reference to a national code

Ref country code: CH

Ref legal event code: NV

Representative=s name: ISLER & PEDRAZZINI AG

Ref country code: CH

Ref legal event code: EP

GBT Gb: translation of ep patent filed (gb section 77(6)(a)/1977)

Effective date: 19980305

REF Corresponds to:

Ref document number: 59501518

Country of ref document: DE

Date of ref document: 19980409

ITF It: translation for a ep patent filed
REG Reference to a national code

Ref country code: ES

Ref legal event code: FG2A

Ref document number: 2115284

Country of ref document: ES

Kind code of ref document: T3

ET Fr: translation filed
PLBE No opposition filed within time limit

Free format text: ORIGINAL CODE: 0009261

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT

26N No opposition filed
REG Reference to a national code

Ref country code: CH

Ref legal event code: PFA

Free format text: EPPENDORF-NETHELER-HINZ GMBH TRANSFER- EPPENDORF AG

REG Reference to a national code

Ref country code: FR

Ref legal event code: CJ

Ref country code: FR

Ref legal event code: CD

NLS Nl: assignments of ep-patents

Owner name: EPPENDORF AG

REG Reference to a national code

Ref country code: GB

Ref legal event code: IF02

REG Reference to a national code

Ref country code: CH

Ref legal event code: PCAR

Free format text: ISLER & PEDRAZZINI AG;POSTFACH 1772;8027 ZUERICH (CH)

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: CH

Payment date: 20130322

Year of fee payment: 19

Ref country code: LU

Payment date: 20130328

Year of fee payment: 19

Ref country code: SE

Payment date: 20130321

Year of fee payment: 19

Ref country code: ES

Payment date: 20130314

Year of fee payment: 19

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: NL

Payment date: 20130320

Year of fee payment: 19

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: AT

Payment date: 20130313

Year of fee payment: 19

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: BE

Payment date: 20130320

Year of fee payment: 19

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: DE

Payment date: 20140328

Year of fee payment: 20

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: FR

Payment date: 20140319

Year of fee payment: 20

Ref country code: IT

Payment date: 20140325

Year of fee payment: 20

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: GB

Payment date: 20140319

Year of fee payment: 20

REG Reference to a national code

Ref country code: NL

Ref legal event code: V1

Effective date: 20141001

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LU

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20140323

REG Reference to a national code

Ref country code: CH

Ref legal event code: PL

REG Reference to a national code

Ref country code: SE

Ref legal event code: EUG

REG Reference to a national code

Ref country code: AT

Ref legal event code: MM01

Ref document number: 163572

Country of ref document: AT

Kind code of ref document: T

Effective date: 20140323

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: SE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20140324

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: CH

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20140331

Ref country code: LI

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20140331

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: AT

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20140323

Ref country code: NL

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20141001

REG Reference to a national code

Ref country code: DE

Ref legal event code: R071

Ref document number: 59501518

Country of ref document: DE

REG Reference to a national code

Ref country code: GB

Ref legal event code: PE20

Expiry date: 20150322

REG Reference to a national code

Ref country code: ES

Ref legal event code: FD2A

Effective date: 20150427

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: GB

Free format text: LAPSE BECAUSE OF EXPIRATION OF PROTECTION

Effective date: 20150322

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: ES

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20140324

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: BE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20140331