EP0679440B1 - Pipette de distribution à répétition - Google Patents

Pipette de distribution à répétition Download PDF

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Publication number
EP0679440B1
EP0679440B1 EP95104357A EP95104357A EP0679440B1 EP 0679440 B1 EP0679440 B1 EP 0679440B1 EP 95104357 A EP95104357 A EP 95104357A EP 95104357 A EP95104357 A EP 95104357A EP 0679440 B1 EP0679440 B1 EP 0679440B1
Authority
EP
European Patent Office
Prior art keywords
rack
operating
operating element
syringe
withholding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
EP95104357A
Other languages
German (de)
English (en)
Other versions
EP0679440A1 (fr
Inventor
Herbert Belgardt
Klaus Ing. Schürbrock (grad.)
Rolf-Günter Meyer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eppendorf SE
Original Assignee
Eppendorf Netheler Hinz GmbH
Eppendorf Geraetebau Netheler and Hinz GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eppendorf Netheler Hinz GmbH, Eppendorf Geraetebau Netheler and Hinz GmbH filed Critical Eppendorf Netheler Hinz GmbH
Publication of EP0679440A1 publication Critical patent/EP0679440A1/fr
Application granted granted Critical
Publication of EP0679440B1 publication Critical patent/EP0679440B1/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • B01L3/0234—Repeating pipettes, i.e. for dispensing multiple doses from a single charge

Definitions

  • the invention relates to a repeater pipette according to the Preamble of claim 1.
  • a repeating pipette of the above type is known from DE 29 26 691 C2 known.
  • the syringe holder is one U-shaped groove with a side opening in a pipette housing, through which a syringe flange can be inserted is.
  • the syringe flange is in the receptacle Compression spring loaded in the direction of the discharge opening.
  • the Syringe plunger has a cylindrical actuation section by means of a clamping device in the receiving body is fixable.
  • the piston return device is a lever emanating from the receiving body, which by a side housing slot protrudes. By pushing the The piston is out of the lever away from the syringe holder Removable syringe.
  • the actuating element of the piston feed device is one on the toothless side the rack pivotally mounted operating lever, the the pawl and an actuating end protruding from the housing on the toothed side of the rack.
  • the Barrier element of the increment setting device is one Tongue, the toothing of the rack depending on the setting of a rotary knob more or less covered. in the The tongue holds the latch when the lever is actuated from an intervention in the rack. By doing the pawl engages in the toothing and takes this and the associated piston around a feed step with. The width of the advance step and thus the volume delivered by the syringe are therefore adjustable using the rotary knob.
  • the actuation path of the actuation lever exposes itself an empty path in which the pawl from the tongue at the tooth mesh is prevented, and a commute in which the pawl engages in the teeth.
  • the empty path is the bigger and the way to work, the smaller the smaller the set increment and the smaller the volume of liquid to be dosed.
  • An operator has the operating lever over the at many settings to swing predominantly empty path, even though the Piston does not move in the syringe.
  • the object of the invention is a repeater pipette of the type mentioned with reduced To create operating effort for an operator.
  • a path limiting device for the actuation path of the actuating element intended.
  • the path limitation device is controlled by the increment setting device that the actuation path increases with increasing step size and is reduced with decreasing step size. Care is taken to ensure that the actuating element is always moved to work, but that at all set increments are reduced Empty path is swept.
  • that the activity is always predominant or exclusive serves to overcome the commute, i.e. the syringe plunger advances. As a result, the operating effort reduced and adapted to the respective dosage amount.
  • the Actuation path is matched to the respective work path, so that it is a measure of the dosing volume and the operator an additional note on the pipette setting gives.
  • the path limiting device preferably has a Limit the actuation path of the actuating element at the beginning Stop on that of the step adjustment device in the forward and backward movement direction of the actuating element is adjustable. To compensate for a the free travel becomes larger when the stop is reduced the increment in the direction of advance of the actuating element adjusted. When increasing the step size for larger amounts of liquid, the stop is in Return movement direction of the actuator moves, so that a sufficient commute and, if necessary, a desired free travel is available.
  • the stop is preferred as a shoulder of the holding element slidable along the rack, making it a practical constant idle travel is realized.
  • the route of operation is corresponding to that by means of the holding element set travel distance reduced or enlarged.
  • the stop is preferably at a distance of one arranged front end of the holding element. When actuated can then use the jack over a certain free travel the restraining element cooperate before being in the toothing intervenes.
  • the holding element can be guided on the rack Be sleeve.
  • the stop is preferably a lateral shoulder the sleeve.
  • the actuating element is extends across one side of the rack.
  • the blocking element can be the paragraph on this side of the Have rack.
  • the actuator can two parallel legs on opposite one another Have sides of the rack and the holding element on have the paragraph on both sides.
  • the actuating element a swivel bearing on one side of the rack and an actuating end on the other side of the rack to have.
  • the holding element is a has laterally projecting guide cams in a Guide curve of a rotatable adjusting knob as an adjusting element the step size setting is performed.
  • This known setting device of the holding element is particularly beneficial if it is the shift at the same time of the attack.
  • the rack is a rod with a Teeth, also as a threaded rod or as a rod can be carried out with circumferential grooves.
  • the repeater pipette has a housing 1, which acts as a handle executed central section 2, a foot section 3 and has a head section 4.
  • a syringe holder 5 for a syringe flange syringe 6 partially shown in broken lines.
  • the foot section 3 has an end face Provide inlet opening 7 for the syringe body.
  • the middle section 2 has a guide 8 in the inside designed as a sliding block receiving body 9 for the actuating end the syringe plunger is guided.
  • the receiving body 9 has a - not shown - clamping device with which the inserted actuation end can be fixed is.
  • the receiving body 9 has a push-back lever 10, which protrudes from a slot 11 in the left side of the housing.
  • the receptacle body 9 carries on the one facing away from the receptacle 5 Front 12 a rack 13, which is characterized by the middle section 2 to the head section 4 of the housing 1 extends.
  • the rack 13 has a flat cross section, that on a narrow side with a sawtooth Teeth 14 is provided. The steeper flank of the teeth 14 faces the head section 4.
  • the operating lever 17 has two parallel ones Leg 18, 18 'and protrudes with an actuating end from a slot 19 in the opposite side of the housing out. Between the operating lever 17 and the housing 1 acts a tension spring 20, the operating lever biased towards the head section 4.
  • a pawl 22 which 1 with its end of engagement in the toothing 14 intervenes.
  • the pawl 22 is by means of one on it and the Operating lever 17 supported - not shown - Leg spring biased towards the rack 13.
  • a holding element 23 in Form of a sleeve extends to the rack 13.
  • the sleeve 23 covers part of the toothing 14 with a holding surface 24 from. It can be moved along the rack 13. For this, she has near her rack 13 away end a pin 25 which is in a guide curve 26 of a rotary knob mounted on the head section 4 27 engages.
  • the position of the sleeve 23 in the housing 1 and the extent of their overlap with the toothing is 14 adjustable by turning the rotary knob 27.
  • the sleeve 23 has on the side surfaces 28, 28 'to the outside projecting paragraphs 29, 29 '.
  • Form paragraphs 29, 29 ' Stops for the parallel legs 18, 18 'of the lever 17, which the sleeve 23 or the rack 13 between to record oneself.
  • the stops 29, 29 ' have the lever 17th towards a taper 30, 30 ', which is a clear plant ensure the legs 18, 18 '.
  • the repeater pipette works as follows: First, a syringe 6 is inserted through the inlet opening 7 with its flange into the syringe holder 5 and with its actuating end into the holder body 9. It is clamped in the syringe holder 5 and in the holder body 9 by means not shown. To fill the syringe 6, the receiving body 9 can be pushed back in the R direction by means of the push-back lever 10. 1 to 3 show the repeater pipette with the receiving body 9 withdrawn in the ready position for dispensing liquid.
  • the sleeve 23 is by means of the rotary knob 27 withdrawn in the reverse direction R at most.
  • the Actuating lever 17 is pivoted back so far by the tension spring 20, as the slot 19 in the housing 1 allows.
  • the pawl 22 is just supported on the holding surface 24 from the sleeve 23.
  • the pawl 22 falls directly over the front end of the sleeve 23 in the teeth 14 and takes the rack 13 in the feed direction V with. Practically the entire actuation path B of the actuation lever 17 becomes as a commute for taking the rack 13 and that Dosing of liquid used.
  • the sleeve 23 is by adjusting the knob 27 pushed maximum over the rack 13. Just four teeth of the toothing 14 are still to be taken along through the pawl 22 free.
  • the operating lever 17 is on his legs 18, 18 'from paragraphs 29, 29' of the sleeve 23 pressed in the feed direction V.
  • the distance of the Stops 29, 29 'from the front end of the sleeve 23 are dimensioned that the pawl 22 with a certain distance from the front end according to an empty path on the holding surface 24 rests.
  • lever 17 When lever 17 is actuated, it slides first the pawl 22 along the empty path over the holding surface 24 and is by this at a serration hindered.
  • the rest of the actuation path B is with Pawl engagement in the toothing 14 and is connected used as a way to work.
  • FIG. 1 shows that by setting a smaller step size a considerably reduced actuation path B connected is.
  • the Actuation path changed in proportion to the way to work. Of the Free travel is - as long as lever 17 is not out of the limit the slot 19 is retained - practically constant and is by the distance of the stops 29, 29 'from determined front end of the sleeve 23.

Claims (8)

  1. Pipette à répétition présentant un logement de seringue (5) pour la partie fixation d'une seringue (6), un corps de logement (9) comportant un logement de piston pour la partie commande d'un piston de seringue, un dispositif de retrait du piston (10) pour faire reculer le corps de logement hors du logement de seringue, un dispositif d'avance (13, 17, 22) de piston pour faire avancer le corps de logement vers le logement de seringue, qui comporte une crémaillère (13) liée au corps de logement, un élément de commande (17) mobile le long d'une course de commande (B) et, fixé à cet élément en pouvant pivoter, un cliquet (22) qui, lors du mouvement d'avance de l'élément de commande, vient en prise avec la denture (14) de la crémaillère et la fait avancer d'un pas et, lors d'un mouvement de recul de l'élément de commande, se dégage de la denture, et un dispositif de réglage de largeur de pas (23, 27) pour régler le pas d'avance, qui comporte un élément de dégagement (23) pouvant coulisser sur la crémaillère au moyen d'un élément de réglage (27) pour dégager le cliquet de la prise avec la crémaillère, caractérisée en ce qu'un dispositif (29, 29') limiteur de course commandé par le dispositif (23, 27) de réglage de largeur de pas agrandit le chemin de commande (B) de l'élément de commande (17) lorsque la largeur du pas augmente et la réduit lorsque la largeur du pas diminue.
  2. Pipette selon la revendication 1, caractérisée en ce que le dispositif de limitation de course présente une butée (29, 29') qui limite au début la course de commande (B) de l'élément de commande (17) et qui peut être réglée par le dispositif de réglage de largeur de pas (23, 27) dans la direction de l'avance et du recul (V et R) de l'élément de commande.
  3. Pipette selon la revendication 2, caractérisée en ce que la butée est un épaulement latéral (29, 29') de l'élément de dégagement (23).
  4. Pipette selon l'une des revendications 1 à 3, caractérisée en ce que l'élément de dégagement est une douille (23) guidée sur la crémaillère (13).
  5. Pipette selon l'une des revendications 3 ou 4, caractérisée en ce que l'élément de commande (17) a une branche (18, 18') s'étendant transversalement sur un côté de la crémaillère (13) et l'élément de dégagement (23) a l'épaulement (29) sur ce côté de la crémaillère (13).
  6. Pipette selon la revendication 5, caractérisée en ce que l'élément de commande (17) a deux branches parallèles (18, 18') sur deux côtés opposés de la crémaillère (13) et l'élément de dégagement (23) présente, sur ses côtés correspondants (28, 28'), des épaulements (29, 29') correspondant aux branches.
  7. Pipette selon la revendication 5 ou 6, caractérisée en ce que l'élément de commande (17) a, sur un côté de la crémaillère (13), une articulation (15) et, sur l'autre côté de la crémaillère, une extrémité de commande.
  8. Pipette selon l'une des revendications 1 à 7, caractérisée en ce que l'élément de dégagement (23) a un ergot de guidage (25) dépassant latéralement, qui est guidé dans une courbe de guidage (26) d'une tête de réglage (27) comme élément de réglage.
EP95104357A 1994-04-27 1995-03-24 Pipette de distribution à répétition Expired - Lifetime EP0679440B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4414744 1994-04-27
DE4414744A DE4414744C1 (de) 1994-04-27 1994-04-27 Repetierpipette

Publications (2)

Publication Number Publication Date
EP0679440A1 EP0679440A1 (fr) 1995-11-02
EP0679440B1 true EP0679440B1 (fr) 1998-03-04

Family

ID=6516601

Family Applications (1)

Application Number Title Priority Date Filing Date
EP95104357A Expired - Lifetime EP0679440B1 (fr) 1994-04-27 1995-03-24 Pipette de distribution à répétition

Country Status (7)

Country Link
US (1) US5573729A (fr)
EP (1) EP0679440B1 (fr)
JP (1) JPH08150207A (fr)
AT (1) ATE163573T1 (fr)
CA (1) CA2147927A1 (fr)
DE (2) DE4414744C1 (fr)
FI (1) FI116202B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9192727B2 (en) 2006-05-18 2015-11-24 Novo Nordisk A/S Injection device with mode locking means

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2838070B2 (ja) * 1996-03-07 1998-12-16 株式会社ニチリョー 反復式ピペット
DE20019821U1 (de) * 1999-12-09 2001-06-07 Brand Gmbh & Co Kg Dosiereinrichtung für Flüssigkeiten
US6663602B2 (en) 2000-06-16 2003-12-16 Novo Nordisk A/S Injection device
ATE480330T1 (de) * 2001-10-16 2010-09-15 Matrix Technologies Corp Hand-pipettiervorrichtung
US20060027033A1 (en) * 2002-10-16 2006-02-09 Richard Cote Hand-held pipette employing voice recognition control
US7284454B2 (en) * 2004-05-27 2007-10-23 Matrix Technologies Corporation Hand held pipette
US7381371B2 (en) * 2004-01-16 2008-06-03 Heathrow Scientific Llc Pipette device with pivotable nozzle assembly
DK1804865T3 (da) 2004-10-21 2010-02-01 Novo Nordisk As Neddrejeindstillingsmekanisme til en pen med fjederoptræk
CN101163514B (zh) 2005-04-24 2012-01-25 诺和诺德公司 注射装置
CN101400394B (zh) * 2006-03-10 2012-07-04 诺沃-诺迪斯克有限公司 具有传动部件的注射装置
JP5062768B2 (ja) 2006-03-10 2012-10-31 ノボ・ノルデイスク・エー／エス 注射装置および該装置のカートリッジを交換する方法
DE602007004972D1 (de) 2006-05-16 2010-04-08 Novo Nordisk As Getriebemechanismus für ein injektionsgerät
CN101641126B (zh) 2007-03-23 2014-06-04 诺沃-诺迪斯克有限公司 包括锁定螺母的注射装置
WO2011056127A1 (fr) * 2009-11-06 2011-05-12 Shl Group Ab Dispositif de délivrance de médicament
DE202010009747U1 (de) * 2010-07-01 2010-11-18 Brand Gmbh + Co Kg Pipette für ein Pipettensystem mit Pipette und Spritze
CA2861706A1 (fr) 2011-12-29 2013-07-04 Novo Nordisk A/S Mecanisme a disque se deplacant vers le haut/vers le bas pour une seringue automatique
WO2014204587A1 (fr) * 2013-06-17 2014-12-24 Waters Technologies Corporation Micropipette d'aliquotage de petits volumes de liquide
JP6640998B2 (ja) 2015-06-05 2020-02-05 ミメタス ビー．ブイ． マイクロ流体プレート

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US2768768A (en) * 1953-02-27 1956-10-30 Gibson Homans Company Calking gun
NL107751C (fr) * 1958-03-22
US3110310A (en) * 1961-07-20 1963-11-12 Ideal Instr & Mfg Co Inc Metering hypodermic syringe
US3141583A (en) * 1962-03-23 1964-07-21 William L Brickson Injection gun
US3606085A (en) * 1968-08-26 1971-09-20 Ian Butler Spilman Dispensing gun for pastes and like substances
DE2926691C2 (de) * 1979-07-02 1983-05-26 Eppendorf Gerätebau Netheler + Hinz GmbH, 2000 Hamburg Repetierpipette
US4099548A (en) * 1976-08-25 1978-07-11 Oxford Laboratories Inc. Hand-held pipette for repetitively dispensing precise volumes of liquid
FI58875C (fi) * 1979-08-31 1981-05-11 Suovaniemi Finnpipette Pipett
DE3204178C2 (de) * 1982-02-06 1986-03-20 Eppendorf Gerätebau Netheler + Hinz GmbH, 2000 Hamburg Pipettiervorrichtung
US4467942A (en) * 1982-04-29 1984-08-28 Yuuji Oshikubo Repeating dispenser
DE3216644A1 (de) * 1982-05-04 1983-11-10 Nichiryo Co., Ltd., Tokyo Wiederholspender
EP0109913A3 (fr) * 1982-11-03 1984-09-12 Micro-Mega Seringue dentaire pour injections intra-ligamentaires
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9192727B2 (en) 2006-05-18 2015-11-24 Novo Nordisk A/S Injection device with mode locking means

Also Published As

Publication number Publication date
JPH08150207A (ja) 1996-06-11
US5573729A (en) 1996-11-12
DE4414744C1 (de) 1995-11-02
FI951977A0 (fi) 1995-04-26
ATE163573T1 (de) 1998-03-15
FI951977A (fi) 1995-10-28
DE59501519D1 (de) 1998-04-09
FI116202B (fi) 2005-10-14
EP0679440A1 (fr) 1995-11-02
CA2147927A1 (fr) 1995-10-28

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