EG25613A - Thienopyrimidinediones and their use in the modulation of autoimmune disease - Google Patents

Thienopyrimidinediones and their use in the modulation of autoimmune disease

Info

Publication number
EG25613A
EG25613A EGNA2005000380A EG25613A EG 25613 A EG25613 A EG 25613A EG NA2005000380 A EGNA2005000380 A EG NA2005000380A EG 25613 A EG25613 A EG 25613A
Authority
EG
Egypt
Prior art keywords
thienopyrimidinediones
sup
modulation
autoimmune disease
compounds
Prior art date
Application number
Other languages
English (en)
Inventor
Simon David Guile
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of EG25613A publication Critical patent/EG25613A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
EGNA2005000380 2003-01-17 2005-07-12 Thienopyrimidinediones and their use in the modulation of autoimmune disease EG25613A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0300119A SE0300119D0 (sv) 2003-01-17 2003-01-17 Novel compounds
PCT/SE2004/000052 WO2004065394A1 (en) 2003-01-17 2004-01-15 Thienopyrimidinediones and their use in the modulation of autoimmune disease

Publications (1)

Publication Number Publication Date
EG25613A true EG25613A (en) 2012-03-22

Family

ID=20290154

Family Applications (1)

Application Number Title Priority Date Filing Date
EGNA2005000380 EG25613A (en) 2003-01-17 2005-07-12 Thienopyrimidinediones and their use in the modulation of autoimmune disease

Country Status (24)

Country Link
US (2) US7384951B2 (sv)
EP (1) EP1587812B1 (sv)
JP (1) JP4519121B2 (sv)
KR (2) KR101107486B1 (sv)
CN (1) CN100334093C (sv)
AT (1) ATE335748T1 (sv)
AU (1) AU2004206012B2 (sv)
BR (1) BRPI0406801B8 (sv)
CA (1) CA2512441C (sv)
DE (1) DE602004001857T2 (sv)
EG (1) EG25613A (sv)
ES (1) ES2270337T3 (sv)
HK (1) HK1081959A1 (sv)
IL (1) IL169370A (sv)
IS (1) IS2376B (sv)
MX (1) MXPA05007496A (sv)
NO (1) NO333702B1 (sv)
NZ (1) NZ541217A (sv)
PL (1) PL214682B1 (sv)
RU (1) RU2331647C2 (sv)
SE (1) SE0300119D0 (sv)
UA (1) UA81788C2 (sv)
WO (1) WO2004065394A1 (sv)
ZA (1) ZA200505364B (sv)

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GB0117583D0 (en) * 2001-07-19 2001-09-12 Astrazeneca Ab Novel compounds
GB0118479D0 (en) * 2001-07-28 2001-09-19 Astrazeneca Ab Novel compounds
PL378221A1 (pl) * 2003-01-17 2006-03-20 Astrazeneca Ab Tienopirydazynony i ich zastosowanie w modulacji choroby autoimmunologicznej
SE0300120D0 (sv) * 2003-01-17 2003-01-17 Astrazeneca Ab Novel compounds
AU2004308299B2 (en) 2003-12-19 2011-11-24 Plexxikon, Inc. Compounds and methods for development of Ret modulators
US7498342B2 (en) 2004-06-17 2009-03-03 Plexxikon, Inc. Compounds modulating c-kit activity
BRPI0610066A2 (pt) 2005-05-17 2010-05-25 Plexxikon Inc compostos que modulam atividade de c-kit e c-fms e usos para estes
EP2395004B1 (en) 2005-06-22 2016-01-20 Plexxikon Inc. Pyrrolo [2,3-b]pyridine derivatives as protein kinase inhibitors
WO2008063888A2 (en) 2006-11-22 2008-05-29 Plexxikon, Inc. Compounds modulating c-fms and/or c-kit activity and uses therefor
PE20121126A1 (es) 2006-12-21 2012-08-24 Plexxikon Inc Compuestos pirrolo [2,3-b] piridinas como moduladores de quinasa
WO2008079909A1 (en) 2006-12-21 2008-07-03 Plexxikon, Inc. Pyrrolo [2,3-b] pyridines as kinase modulators
BRPI0720695A2 (pt) 2006-12-21 2014-02-18 Plexxikon Inc Compostos e métodos para modulação de cinase, e indicações para estes
GB0713479D0 (en) * 2007-07-11 2007-08-22 Syngenta Participations Ag Substituted aromatic heterocyclic compounds as fungicides
BRPI0814423B1 (pt) 2007-07-17 2022-04-19 Plexxikon, Inc Compostos que modulam quinase e composição farmacêutica compreendendo os mesmos
WO2010089580A1 (en) 2009-02-06 2010-08-12 Astrazeneca Ab Use of a mct1 inhibitor in the treatment of cancers expressing mct1 over mct4
KR20120001746A (ko) * 2009-03-23 2012-01-04 그렌마크 파머수티칼스 에스. 아. Ｔｒｐａ1 조절자로서 이소티아졸로-피리미딘디온 유도체
PL2411395T3 (pl) * 2009-03-23 2013-10-31 Glenmark Pharmaceuticals Sa Pochodne furopirymidynodionu jako modulatory TRPA1
AU2010232670B2 (en) 2009-04-03 2015-07-09 F. Hoffmann-La Roche Ag Propane- I-sulfonic acid {3- [5- (4 -chloro-phenyl) -1H-pyrrolo [2, 3-b] pyridine-3-carbonyl] -2, 4-difluoro-pheny l } -amide compositions and uses thereof
US8329724B2 (en) 2009-08-03 2012-12-11 Hoffmann-La Roche Inc. Process for the manufacture of pharmaceutically active compounds
BR112012012156A2 (pt) 2009-11-06 2015-09-08 Plexxikon Inc compostos e métodos para modulação de cinase, e indicações para esta
BR112013020041B1 (pt) 2011-02-07 2021-11-23 Plexxikon, Inc Compostos e composições para a modulação de quinases e uso dos mesmos
AR085279A1 (es) 2011-02-21 2013-09-18 Plexxikon Inc Formas solidas de {3-[5-(4-cloro-fenil)-1h-pirrolo[2,3-b]piridina-3-carbonil]-2,4-difluor-fenil}-amida del acido propano-1-sulfonico
US9296728B2 (en) 2012-01-20 2016-03-29 Regents Of The University Of Minnesota Therapeutic compounds
GB2523211B (en) 2012-01-27 2020-03-18 Univ Jefferson MCT protein inhibitor-related prognostic and therapeutic methods
US9150570B2 (en) 2012-05-31 2015-10-06 Plexxikon Inc. Synthesis of heterocyclic compounds
US10022372B2 (en) 2013-04-19 2018-07-17 Thomas Jefferson University Caveolin-1 related methods for treating glioblastoma with temozolomide
KR102228034B1 (ko) * 2013-10-21 2021-03-16 제노스코 치환된 피리미딘 화합물 및 syk 억제제로서의 이의 용도
US10329303B2 (en) * 2015-01-22 2019-06-25 The Scripps Research Institute Heterocyclic inhibitors of monocarboxylate transporter
UY36586A (es) * 2015-03-26 2016-10-31 Bayer Pharma AG Heterociclilmetiltienouracilos y uso de los mismos
KR101712836B1 (ko) * 2016-03-17 2017-03-22 주식회사 골프존 가상 골프 시뮬레이션 장치, 가상 골프를 위한 영상 구현 방법 및 이를 기록한 컴퓨팅 장치에 의해 판독 가능한 기록 매체
KR101712838B1 (ko) * 2016-03-17 2017-03-07 주식회사 골프존 가상 골프 시뮬레이션 장치, 가상 골프를 위한 영상 구현 방법 및 이를 기록한 컴퓨팅 장치에 의해 판독 가능한 기록 매체
KR101730536B1 (ko) * 2016-03-17 2017-05-02 주식회사 골프존 스크린 골프 시스템에서 구현되는 컨텐츠 전송 서비스 방법, 컨텐츠 전송 서비스를 위한 모바일 단말기의 제어방법 및 이를 기록한 컴퓨팅 장치에 의해 판독 가능한 기록매체
TWI823932B (zh) 2018-05-11 2023-12-01 中國大陸商迪哲（江蘇）醫藥有限公司 三唑并嘧啶化合物及其在治療癌症中之用途

Family Cites Families (11)

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Publication number Priority date Publication date Assignee Title
US738495A (en) * 1902-12-26 1903-09-08 William E Sherwood Thill-coupling.
SE9702001D0 (sv) * 1997-05-28 1997-05-28 Astra Pharma Prod Novel compounds
US6469014B1 (en) * 1997-05-28 2002-10-22 Astrazeneca Ab Thieno[2,3-d] pyrimidinediones, their preparation and use in therapy
PL340836A1 (en) 1997-12-05 2001-02-26 Astrazeneca Uk Ltd Novel compounds
US6232320B1 (en) 1998-06-04 2001-05-15 Abbott Laboratories Cell adhesion-inhibiting antiinflammatory compounds
WO2000012514A1 (en) 1998-08-28 2000-03-09 Astrazeneca Ab Novel compounds
DE60104677T2 (de) * 2000-05-04 2005-07-28 Astrazeneca Ab THIENO[2,3-d]PYRIMIDINDIONE UND IHRE VERWENDUNG ALS PHARMAZEUTISCHE MITTEL
GB0117583D0 (en) * 2001-07-19 2001-09-12 Astrazeneca Ab Novel compounds
GB0118479D0 (en) * 2001-07-28 2001-09-19 Astrazeneca Ab Novel compounds
PL378221A1 (pl) 2003-01-17 2006-03-20 Astrazeneca Ab Tienopirydazynony i ich zastosowanie w modulacji choroby autoimmunologicznej
SE0300120D0 (sv) 2003-01-17 2003-01-17 Astrazeneca Ab Novel compounds

Also Published As

Publication number Publication date
PL214682B1 (pl) 2013-09-30
PL378222A1 (pl) 2006-03-20
US7384951B2 (en) 2008-06-10
IS7965A (is) 2005-07-29
DE602004001857D1 (de) 2006-09-21
AU2004206012A1 (en) 2004-08-05
CN100334093C (zh) 2007-08-29
IL169370A (en) 2011-05-31
NO20053826D0 (no) 2005-08-15
IL169370A0 (en) 2007-07-04
US20080214579A1 (en) 2008-09-04
CA2512441A1 (en) 2004-08-05
SE0300119D0 (sv) 2003-01-17
WO2004065394A1 (en) 2004-08-05
RU2005121494A (ru) 2006-02-10
AU2004206012B2 (en) 2007-06-14
JP4519121B2 (ja) 2010-08-04
KR20050092760A (ko) 2005-09-22
BRPI0406801B8 (pt) 2021-05-25
JP2006516974A (ja) 2006-07-13
NZ541217A (en) 2008-05-30
NO333702B1 (no) 2013-08-26
RU2331647C2 (ru) 2008-08-20
CA2512441C (en) 2012-01-03
EP1587812B1 (en) 2006-08-09
BRPI0406801A (pt) 2006-01-17
KR101107486B1 (ko) 2012-01-19
NO20053826L (no) 2005-10-17
ES2270337T3 (es) 2007-04-01
DE602004001857T2 (de) 2007-05-24
US20060052400A1 (en) 2006-03-09
EP1587812A1 (en) 2005-10-26
ZA200505364B (en) 2006-09-27
MXPA05007496A (es) 2005-09-21
IS2376B (is) 2008-07-15
HK1081959A1 (en) 2006-05-26
KR20110125256A (ko) 2011-11-18
UA81788C2 (uk) 2008-02-11
ATE335748T1 (de) 2006-09-15
CN1761672A (zh) 2006-04-19
BRPI0406801B1 (pt) 2018-04-03

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