EG25613A - Thienopyrimidinediones and their use in the modulation of autoimmune disease - Google Patents

Thienopyrimidinediones and their use in the modulation of autoimmune disease

Info

Publication number
EG25613A
EG25613A EGNA2005000380A EG25613A EG 25613 A EG25613 A EG 25613A EG NA2005000380 A EGNA2005000380 A EG NA2005000380A EG 25613 A EG25613 A EG 25613A
Authority
EG
Egypt
Prior art keywords
thienopyrimidinediones
sup
modulation
autoimmune disease
compounds
Prior art date
Application number
Other languages
English (en)
Inventor
Simon David Guile
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of EG25613A publication Critical patent/EG25613A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
EGNA2005000380 2003-01-17 2005-07-12 Thienopyrimidinediones and their use in the modulation of autoimmune disease EG25613A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0300119A SE0300119D0 (sv) 2003-01-17 2003-01-17 Novel compounds
PCT/SE2004/000052 WO2004065394A1 (en) 2003-01-17 2004-01-15 Thienopyrimidinediones and their use in the modulation of autoimmune disease

Publications (1)

Publication Number Publication Date
EG25613A true EG25613A (en) 2012-03-22

Family

ID=20290154

Family Applications (1)

Application Number Title Priority Date Filing Date
EGNA2005000380 EG25613A (en) 2003-01-17 2005-07-12 Thienopyrimidinediones and their use in the modulation of autoimmune disease

Country Status (24)

Country Link
US (2) US7384951B2 (xx)
EP (1) EP1587812B1 (xx)
JP (1) JP4519121B2 (xx)
KR (2) KR20110125256A (xx)
CN (1) CN100334093C (xx)
AT (1) ATE335748T1 (xx)
AU (1) AU2004206012B2 (xx)
BR (1) BRPI0406801B8 (xx)
CA (1) CA2512441C (xx)
DE (1) DE602004001857T2 (xx)
EG (1) EG25613A (xx)
ES (1) ES2270337T3 (xx)
HK (1) HK1081959A1 (xx)
IL (1) IL169370A (xx)
IS (1) IS2376B (xx)
MX (1) MXPA05007496A (xx)
NO (1) NO333702B1 (xx)
NZ (1) NZ541217A (xx)
PL (1) PL214682B1 (xx)
RU (1) RU2331647C2 (xx)
SE (1) SE0300119D0 (xx)
UA (1) UA81788C2 (xx)
WO (1) WO2004065394A1 (xx)
ZA (1) ZA200505364B (xx)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0117583D0 (en) * 2001-07-19 2001-09-12 Astrazeneca Ab Novel compounds
GB0118479D0 (en) 2001-07-28 2001-09-19 Astrazeneca Ab Novel compounds
SE0300120D0 (sv) 2003-01-17 2003-01-17 Astrazeneca Ab Novel compounds
NZ541218A (en) * 2003-01-17 2008-05-30 Astrazeneca Ab Thienopyrimidinediones and their use in modulation of autoimmune disease
EP1696920B8 (en) 2003-12-19 2015-05-06 Plexxikon Inc. Compounds and methods for development of ret modulators
US7498342B2 (en) 2004-06-17 2009-03-03 Plexxikon, Inc. Compounds modulating c-kit activity
KR20080027775A (ko) 2005-05-17 2008-03-28 플렉시콘, 인코퍼레이티드 피롤(２,３-ｂ)피리딘 유도체 단백질 키나제 억제제
CN102603581B (zh) 2005-06-22 2015-06-24 普莱希科公司 作为蛋白质激酶抑制剂的吡咯并[2,3-b]吡啶衍生物
WO2008063888A2 (en) 2006-11-22 2008-05-29 Plexxikon, Inc. Compounds modulating c-fms and/or c-kit activity and uses therefor
PE20081581A1 (es) 2006-12-21 2008-11-12 Plexxikon Inc COMPUESTOS PIRROLO[2,3-b]PIRIDINAS COMO MODULADORES DE QUINASA
WO2008079909A1 (en) 2006-12-21 2008-07-03 Plexxikon, Inc. Pyrrolo [2,3-b] pyridines as kinase modulators
WO2008080001A2 (en) 2006-12-21 2008-07-03 Plexxikon, Inc. Compounds and methods for kinase modulation, and indications therefor
GB0713479D0 (en) * 2007-07-11 2007-08-22 Syngenta Participations Ag Substituted aromatic heterocyclic compounds as fungicides
US20100190777A1 (en) 2007-07-17 2010-07-29 Plexxikon Inc. Compounds and methods for kinase modulation, and indications therefor
WO2010089580A1 (en) 2009-02-06 2010-08-12 Astrazeneca Ab Use of a mct1 inhibitor in the treatment of cancers expressing mct1 over mct4
SG184767A1 (en) * 2009-03-23 2012-10-30 Glenmark Pharmaceuticals Sa Furopyrimidinedione derivatives as trpa1 modulators
SG174403A1 (en) * 2009-03-23 2011-10-28 Glenmark Pharmaceuticals Sa Isothiazolo-pyrimidinedione derivatives as trpa1 modulators
CR20170089A (es) 2009-04-03 2017-07-17 Plexxikon Inc Composiciones del acido propano-1--sulfonico {3-[5-(4-cloro-fenil)-1h-pirrolo [2,3-b] piridina-3-carbonil] -2,4-difluoro-fenil}-amida y el uso de las mismas
US8329724B2 (en) 2009-08-03 2012-12-11 Hoffmann-La Roche Inc. Process for the manufacture of pharmaceutically active compounds
NZ599866A (en) 2009-11-06 2014-09-26 Plexxikon Inc Compounds and methods for kinase modulation, and indications therefor
MA34948B1 (fr) 2011-02-07 2014-03-01 Plexxikon Inc Composes et procedes de modulation de kinase, et leurs indications
TWI558702B (zh) 2011-02-21 2016-11-21 普雷辛肯公司 醫藥活性物質的固態形式
WO2013109972A2 (en) 2012-01-20 2013-07-25 Regents Of The University Of Minnesota Therapeutic compounds
US10085987B2 (en) 2012-01-27 2018-10-02 Thomas Jefferson University MCT protein inhibitor-related prognostic and therapeutic methods
US9150570B2 (en) 2012-05-31 2015-10-06 Plexxikon Inc. Synthesis of heterocyclic compounds
WO2014172627A1 (en) 2013-04-19 2014-10-23 Thomas Jefferson University Caveolin-1 related methods for treating glioblastoma with temozolomide
AU2014340249B2 (en) * 2013-10-21 2017-05-25 Genosco Substituted pyrimidine compounds and their use as SYK inhibitors
JP6725519B2 (ja) * 2015-01-22 2020-07-22 ザ スクリプス リサーチ インスティテュート 複素環式のモノカルボン酸トランスポータ阻害薬
UY36586A (es) * 2015-03-26 2016-10-31 Bayer Pharma AG Heterociclilmetiltienouracilos y uso de los mismos
KR101730536B1 (ko) * 2016-03-17 2017-05-02 주식회사 골프존 스크린 골프 시스템에서 구현되는 컨텐츠 전송 서비스 방법, 컨텐츠 전송 서비스를 위한 모바일 단말기의 제어방법 및 이를 기록한 컴퓨팅 장치에 의해 판독 가능한 기록매체
KR101712836B1 (ko) * 2016-03-17 2017-03-22 주식회사 골프존 가상 골프 시뮬레이션 장치, 가상 골프를 위한 영상 구현 방법 및 이를 기록한 컴퓨팅 장치에 의해 판독 가능한 기록 매체
KR101712838B1 (ko) * 2016-03-17 2017-03-07 주식회사 골프존 가상 골프 시뮬레이션 장치, 가상 골프를 위한 영상 구현 방법 및 이를 기록한 컴퓨팅 장치에 의해 판독 가능한 기록 매체
TWI823932B (zh) 2018-05-11 2023-12-01 中國大陸商迪哲（江蘇）醫藥有限公司 三唑并嘧啶化合物及其在治療癌症中之用途

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US738495A (en) * 1902-12-26 1903-09-08 William E Sherwood Thill-coupling.
US6469014B1 (en) * 1997-05-28 2002-10-22 Astrazeneca Ab Thieno[2,3-d] pyrimidinediones, their preparation and use in therapy
SE9702001D0 (sv) * 1997-05-28 1997-05-28 Astra Pharma Prod Novel compounds
TR200001603T2 (tr) 1997-12-05 2000-10-23 Astrazeneca Uk Limited Yeni bileşikler
US6232320B1 (en) * 1998-06-04 2001-05-15 Abbott Laboratories Cell adhesion-inhibiting antiinflammatory compounds
WO2000012514A1 (en) * 1998-08-28 2000-03-09 Astrazeneca Ab Novel compounds
EP1280806B1 (en) * 2000-05-04 2004-08-04 AstraZeneca AB THIENO 2,3-d]PYRIMIDINEDIONES AND THEIR USE AS PHARMACEUTICALS
GB0117583D0 (en) * 2001-07-19 2001-09-12 Astrazeneca Ab Novel compounds
GB0118479D0 (en) * 2001-07-28 2001-09-19 Astrazeneca Ab Novel compounds
NZ541218A (en) 2003-01-17 2008-05-30 Astrazeneca Ab Thienopyrimidinediones and their use in modulation of autoimmune disease
SE0300120D0 (sv) * 2003-01-17 2003-01-17 Astrazeneca Ab Novel compounds

Also Published As

Publication number Publication date
UA81788C2 (uk) 2008-02-11
BRPI0406801B8 (pt) 2021-05-25
DE602004001857D1 (de) 2006-09-21
US20060052400A1 (en) 2006-03-09
MXPA05007496A (es) 2005-09-21
EP1587812B1 (en) 2006-08-09
PL214682B1 (pl) 2013-09-30
US7384951B2 (en) 2008-06-10
NZ541217A (en) 2008-05-30
PL378222A1 (pl) 2006-03-20
AU2004206012B2 (en) 2007-06-14
CN1761672A (zh) 2006-04-19
ES2270337T3 (es) 2007-04-01
RU2331647C2 (ru) 2008-08-20
CA2512441A1 (en) 2004-08-05
IL169370A (en) 2011-05-31
RU2005121494A (ru) 2006-02-10
KR20050092760A (ko) 2005-09-22
BRPI0406801A (pt) 2006-01-17
CA2512441C (en) 2012-01-03
NO20053826L (no) 2005-10-17
KR101107486B1 (ko) 2012-01-19
KR20110125256A (ko) 2011-11-18
JP4519121B2 (ja) 2010-08-04
WO2004065394A1 (en) 2004-08-05
ZA200505364B (en) 2006-09-27
US20080214579A1 (en) 2008-09-04
IS7965A (is) 2005-07-29
SE0300119D0 (sv) 2003-01-17
NO333702B1 (no) 2013-08-26
AU2004206012A1 (en) 2004-08-05
CN100334093C (zh) 2007-08-29
EP1587812A1 (en) 2005-10-26
JP2006516974A (ja) 2006-07-13
HK1081959A1 (en) 2006-05-26
BRPI0406801B1 (pt) 2018-04-03
IL169370A0 (en) 2007-07-04
ATE335748T1 (de) 2006-09-15
DE602004001857T2 (de) 2007-05-24
IS2376B (is) 2008-07-15
NO20053826D0 (no) 2005-08-15

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