IS7965A - Þíenópýrimidíndíón og notkun þeirra í breytingu ásjálfsnæmissjúkdómi - Google Patents
Þíenópýrimidíndíón og notkun þeirra í breytingu ásjálfsnæmissjúkdómiInfo
- Publication number
- IS7965A IS7965A IS7965A IS7965A IS7965A IS 7965 A IS7965 A IS 7965A IS 7965 A IS7965 A IS 7965A IS 7965 A IS7965 A IS 7965A IS 7965 A IS7965 A IS 7965A
- Authority
- IS
- Iceland
- Prior art keywords
- thienopyrimidinedione
- sup
- self
- development
- hypersensitivity disease
- Prior art date
Links
- QAFVXBQPQCSSLI-UHFFFAOYSA-N 1h-thieno[3,2-d]pyrimidine-2,4-dione Chemical compound O=C1NC(=O)NC2=C1SC=C2 QAFVXBQPQCSSLI-UHFFFAOYSA-N 0.000 title 1
- 206010020751 Hypersensitivity Diseases 0.000 title 1
- 208000026935 allergic disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 238000002560 therapeutic procedure Methods 0.000 abstract 2
- 206010062016 Immunosuppression Diseases 0.000 abstract 1
- 230000001506 immunosuppresive effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0300119A SE0300119D0 (sv) | 2003-01-17 | 2003-01-17 | Novel compounds |
| PCT/SE2004/000052 WO2004065394A1 (en) | 2003-01-17 | 2004-01-15 | Thienopyrimidinediones and their use in the modulation of autoimmune disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IS7965A true IS7965A (is) | 2005-07-29 |
| IS2376B IS2376B (is) | 2008-07-15 |
Family
ID=20290154
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IS7965A IS2376B (is) | 2003-01-17 | 2005-07-29 | Þíenópýrimidíndíón og notkun þeirra í breytingu ásjálfsnæmissjúkdómi |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US7384951B2 (is) |
| EP (1) | EP1587812B1 (is) |
| JP (1) | JP4519121B2 (is) |
| KR (2) | KR101107486B1 (is) |
| CN (1) | CN100334093C (is) |
| AT (1) | ATE335748T1 (is) |
| AU (1) | AU2004206012B2 (is) |
| BR (1) | BRPI0406801B8 (is) |
| CA (1) | CA2512441C (is) |
| DE (1) | DE602004001857T2 (is) |
| EG (1) | EG25613A (is) |
| ES (1) | ES2270337T3 (is) |
| IL (1) | IL169370A (is) |
| IS (1) | IS2376B (is) |
| MX (1) | MXPA05007496A (is) |
| NO (1) | NO333702B1 (is) |
| NZ (1) | NZ541217A (is) |
| PL (1) | PL214682B1 (is) |
| RU (1) | RU2331647C2 (is) |
| SE (1) | SE0300119D0 (is) |
| UA (1) | UA81788C2 (is) |
| WO (1) | WO2004065394A1 (is) |
| ZA (1) | ZA200505364B (is) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0117583D0 (en) | 2001-07-19 | 2001-09-12 | Astrazeneca Ab | Novel compounds |
| GB0118479D0 (en) * | 2001-07-28 | 2001-09-19 | Astrazeneca Ab | Novel compounds |
| SE0300120D0 (sv) * | 2003-01-17 | 2003-01-17 | Astrazeneca Ab | Novel compounds |
| RU2332420C2 (ru) * | 2003-01-17 | 2008-08-27 | Астразенека Аб | Тиенопиримидиндионы и их применение в модулировании аутоиммунного заболевания |
| US7504509B2 (en) | 2003-12-19 | 2009-03-17 | Plexxikon, Inc. | Compounds and methods for development of Ret modulators |
| US7498342B2 (en) | 2004-06-17 | 2009-03-03 | Plexxikon, Inc. | Compounds modulating c-kit activity |
| MX2007014377A (es) | 2005-05-17 | 2008-02-06 | Plexxikon Inc | Inhibidores de proteina cinasa de derivados de pirrol (2,3-b) piridina. |
| UA95244C2 (ru) | 2005-06-22 | 2011-07-25 | Плексикон, Инк. | Соединения и способ модулирования активности киназ, и показания для их применения |
| WO2008063888A2 (en) | 2006-11-22 | 2008-05-29 | Plexxikon, Inc. | Compounds modulating c-fms and/or c-kit activity and uses therefor |
| JP2010514695A (ja) | 2006-12-21 | 2010-05-06 | プレキシコン，インコーポレーテッド | キナーゼ調節のための化合物および方法およびそのための適応症 |
| WO2008079909A1 (en) | 2006-12-21 | 2008-07-03 | Plexxikon, Inc. | Pyrrolo [2,3-b] pyridines as kinase modulators |
| PE20081581A1 (es) | 2006-12-21 | 2008-11-12 | Plexxikon Inc | COMPUESTOS PIRROLO[2,3-b]PIRIDINAS COMO MODULADORES DE QUINASA |
| GB0713479D0 (en) * | 2007-07-11 | 2007-08-22 | Syngenta Participations Ag | Substituted aromatic heterocyclic compounds as fungicides |
| EP2170830B1 (en) | 2007-07-17 | 2014-10-15 | Plexxikon, Inc. | 2-FLUORO-BENZENESULFONAMIDE COMPOUNDS AS Raf KINASE MODULATORS |
| WO2010089580A1 (en) | 2009-02-06 | 2010-08-12 | Astrazeneca Ab | Use of a mct1 inhibitor in the treatment of cancers expressing mct1 over mct4 |
| SG174403A1 (en) * | 2009-03-23 | 2011-10-28 | Glenmark Pharmaceuticals Sa | Isothiazolo-pyrimidinedione derivatives as trpa1 modulators |
| DK2411395T3 (da) * | 2009-03-23 | 2013-08-05 | Glenmark Pharmaceuticals Sa | Furopyrimidindionderivater som modulatorer for TRPA1 |
| ES2552386T3 (es) | 2009-04-03 | 2015-11-27 | F. Hoffmann-La Roche Ag | Composiciones de {3-[5-(4-cloro-fenil)-1H-pirrol[2,3-b]piridin-3-carbonil]-2,4-difluoro-fenil}-amida del ácido propano-1-sulfónico y usos de las mismas |
| US8329724B2 (en) | 2009-08-03 | 2012-12-11 | Hoffmann-La Roche Inc. | Process for the manufacture of pharmaceutically active compounds |
| EA201290210A1 (ru) | 2009-11-06 | 2012-10-30 | Плексксикон, Инк. | Соединения и способы модуляции киназы и показания для их применения |
| SMT201900112T1 (it) | 2011-02-07 | 2019-02-28 | Plexxikon Inc | Composti e metodi per la modulazione della chinasi, e indicazioni corrispettive |
| AR085279A1 (es) | 2011-02-21 | 2013-09-18 | Plexxikon Inc | Formas solidas de {3-[5-(4-cloro-fenil)-1h-pirrolo[2,3-b]piridina-3-carbonil]-2,4-difluor-fenil}-amida del acido propano-1-sulfonico |
| US9296728B2 (en) | 2012-01-20 | 2016-03-29 | Regents Of The University Of Minnesota | Therapeutic compounds |
| WO2013112881A1 (en) | 2012-01-27 | 2013-08-01 | Thomas Jefferson University | Mct protein inhibitor-related prognostic and therapeutic methods |
| US9150570B2 (en) | 2012-05-31 | 2015-10-06 | Plexxikon Inc. | Synthesis of heterocyclic compounds |
| US10022372B2 (en) | 2013-04-19 | 2018-07-17 | Thomas Jefferson University | Caveolin-1 related methods for treating glioblastoma with temozolomide |
| CN105940000B (zh) * | 2013-10-21 | 2019-12-24 | 盖诺斯克公司 | 取代的嘧啶化合物及其作为syk抑制剂的用途 |
| WO2016118825A1 (en) | 2015-01-22 | 2016-07-28 | The Scripps Research Institute | Heterocyclic inhibitors of monocarboxylate transporters |
| UY36586A (es) * | 2015-03-26 | 2016-10-31 | Bayer Pharma AG | Heterociclilmetiltienouracilos y uso de los mismos |
| KR101712836B1 (ko) * | 2016-03-17 | 2017-03-22 | 주식회사 골프존 | 가상 골프 시뮬레이션 장치, 가상 골프를 위한 영상 구현 방법 및 이를 기록한 컴퓨팅 장치에 의해 판독 가능한 기록 매체 |
| KR101730536B1 (ko) * | 2016-03-17 | 2017-05-02 | 주식회사 골프존 | 스크린 골프 시스템에서 구현되는 컨텐츠 전송 서비스 방법, 컨텐츠 전송 서비스를 위한 모바일 단말기의 제어방법 및 이를 기록한 컴퓨팅 장치에 의해 판독 가능한 기록매체 |
| KR101712838B1 (ko) * | 2016-03-17 | 2017-03-07 | 주식회사 골프존 | 가상 골프 시뮬레이션 장치, 가상 골프를 위한 영상 구현 방법 및 이를 기록한 컴퓨팅 장치에 의해 판독 가능한 기록 매체 |
| TWI823932B (zh) | 2018-05-11 | 2023-12-01 | 中國大陸商迪哲（江蘇）醫藥有限公司 | 三唑并嘧啶化合物及其在治療癌症中之用途 |
| CN119080799A (zh) * | 2024-09-27 | 2024-12-06 | 山东大学 | 一种n-羟基噻吩并嘧啶二酮类衍生物及其制备方法与应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US738495A (en) * | 1902-12-26 | 1903-09-08 | William E Sherwood | Thill-coupling. |
| SE9702001D0 (sv) * | 1997-05-28 | 1997-05-28 | Astra Pharma Prod | Novel compounds |
| US6469014B1 (en) * | 1997-05-28 | 2002-10-22 | Astrazeneca Ab | Thieno[2,3-d] pyrimidinediones, their preparation and use in therapy |
| NZ504452A (en) | 1997-12-05 | 2002-05-31 | Astrazeneca Uk Ltd | [3,4-d]Pyridazinones, process for their preparation and pharmaceutical compositions containing them |
| US6232320B1 (en) * | 1998-06-04 | 2001-05-15 | Abbott Laboratories | Cell adhesion-inhibiting antiinflammatory compounds |
| ES2211161T3 (es) * | 1998-08-28 | 2004-07-01 | Astrazeneca Ab | Tieno(2,3-d)pirimidindionas novedosas, procedimiento para su preparacion y uso de las mismas en terapia. |
| AU2001252825A1 (en) * | 2000-05-04 | 2001-11-12 | Astrazeneca Ab | Thieno(2,3-d)pyrimidinediones and their use as pharmaceuticals |
| GB0117583D0 (en) * | 2001-07-19 | 2001-09-12 | Astrazeneca Ab | Novel compounds |
| GB0118479D0 (en) * | 2001-07-28 | 2001-09-19 | Astrazeneca Ab | Novel compounds |
| RU2332420C2 (ru) | 2003-01-17 | 2008-08-27 | Астразенека Аб | Тиенопиримидиндионы и их применение в модулировании аутоиммунного заболевания |
| SE0300120D0 (sv) * | 2003-01-17 | 2003-01-17 | Astrazeneca Ab | Novel compounds |
-
2003
- 2003-01-17 SE SE0300119A patent/SE0300119D0/xx unknown
-
2004
- 2004-01-15 RU RU2005121494/04A patent/RU2331647C2/ru not_active IP Right Cessation
- 2004-01-15 JP JP2006500750A patent/JP4519121B2/ja not_active Expired - Fee Related
- 2004-01-15 BR BRPI0406801A patent/BRPI0406801B8/pt not_active IP Right Cessation
- 2004-01-15 CA CA2512441A patent/CA2512441C/en not_active Expired - Lifetime
- 2004-01-15 WO PCT/SE2004/000052 patent/WO2004065394A1/en active IP Right Grant
- 2004-01-15 NZ NZ541217A patent/NZ541217A/en not_active IP Right Cessation
- 2004-01-15 CN CNB2004800071073A patent/CN100334093C/zh not_active Expired - Fee Related
- 2004-01-15 AU AU2004206012A patent/AU2004206012B2/en not_active Ceased
- 2004-01-15 AT AT04702477T patent/ATE335748T1/de not_active IP Right Cessation
- 2004-01-15 MX MXPA05007496A patent/MXPA05007496A/es active IP Right Grant
- 2004-01-15 KR KR1020057013126A patent/KR101107486B1/ko not_active Expired - Fee Related
- 2004-01-15 PL PL378222A patent/PL214682B1/pl unknown
- 2004-01-15 US US10/542,197 patent/US7384951B2/en not_active Expired - Lifetime
- 2004-01-15 KR KR1020117022785A patent/KR20110125256A/ko not_active Withdrawn
- 2004-01-15 DE DE602004001857T patent/DE602004001857T2/de not_active Expired - Lifetime
- 2004-01-15 UA UAA200506377A patent/UA81788C2/uk unknown
- 2004-01-15 EP EP04702477A patent/EP1587812B1/en not_active Expired - Lifetime
- 2004-01-15 ES ES04702477T patent/ES2270337T3/es not_active Expired - Lifetime
-
2005
- 2005-06-23 IL IL169370A patent/IL169370A/en active IP Right Grant
- 2005-07-01 ZA ZA2005/05364A patent/ZA200505364B/en unknown
- 2005-07-12 EG EGNA2005000380 patent/EG25613A/xx active
- 2005-07-29 IS IS7965A patent/IS2376B/is unknown
- 2005-08-15 NO NO20053826A patent/NO333702B1/no not_active IP Right Cessation
-
2008
- 2008-05-05 US US12/115,171 patent/US20080214579A1/en not_active Abandoned
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