EG19851A - Process for preparing of 2,4,- 2,5- substituted pyridine - N - oxides - Google Patents
Process for preparing of 2,4,- 2,5- substituted pyridine - N - oxidesInfo
- Publication number
- EG19851A EG19851A EG39291A EG39291A EG19851A EG 19851 A EG19851 A EG 19851A EG 39291 A EG39291 A EG 39291A EG 39291 A EG39291 A EG 39291A EG 19851 A EG19851 A EG 19851A
- Authority
- EG
- Egypt
- Prior art keywords
- oxides
- substituted pyridine
- preparing
- collagen
- fibrosuppressive
- Prior art date
Links
- ILVXOBCQQYKLDS-UHFFFAOYSA-N pyridine N-oxide Chemical class [O-][N+]1=CC=CC=C1 ILVXOBCQQYKLDS-UHFFFAOYSA-N 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 102000008186 Collagen Human genes 0.000 abstract 1
- 108010035532 Collagen Proteins 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 229920001436 collagen Polymers 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000001506 immunosuppresive effect Effects 0.000 abstract 1
- 230000004060 metabolic process Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Pulmonology (AREA)
- Transplantation (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicinal Preparation (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4020570A DE4020570A1 (de) | 1990-06-28 | 1990-06-28 | 2,4- und 2,5-substituierte pyridin-n-oxide, verfahren zu deren herstellung sowie deren verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EG19851A true EG19851A (en) | 1996-10-31 |
Family
ID=6409247
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EG39291A EG19851A (en) | 1990-06-28 | 1991-06-26 | Process for preparing of 2,4,- 2,5- substituted pyridine - N - oxides |
Country Status (27)
| Country | Link |
|---|---|
| EP (1) | EP0463592B1 (cs) |
| JP (1) | JPH0832687B2 (cs) |
| KR (1) | KR920000724A (cs) |
| CN (1) | CN1038585C (cs) |
| AT (1) | ATE110059T1 (cs) |
| AU (1) | AU636990B2 (cs) |
| BR (1) | BR9102699A (cs) |
| CA (1) | CA2045868A1 (cs) |
| CZ (1) | CZ283782B6 (cs) |
| DE (2) | DE4020570A1 (cs) |
| DK (1) | DK0463592T3 (cs) |
| EG (1) | EG19851A (cs) |
| ES (1) | ES2061118T3 (cs) |
| FI (1) | FI101070B (cs) |
| HR (1) | HRP940701B1 (cs) |
| HU (1) | HU214627B (cs) |
| IE (1) | IE65300B1 (cs) |
| IL (1) | IL98629A (cs) |
| LT (1) | LT3918B (cs) |
| MA (1) | MA22191A1 (cs) |
| MX (1) | MX26415A (cs) |
| MY (1) | MY107573A (cs) |
| NO (1) | NO178026C (cs) |
| NZ (1) | NZ238701A (cs) |
| PT (1) | PT98108B (cs) |
| YU (1) | YU113391A (cs) |
| ZA (1) | ZA914958B (cs) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| YU9492A (sh) * | 1991-02-05 | 1995-03-27 | Hoechst Ag. | 2,4- i 2,5-bis-tetrazolilni piridini i postupak za njihovo dobijanje |
| EP0548883A1 (de) * | 1991-12-24 | 1993-06-30 | Hoechst Aktiengesellschaft | Substituierte Pyridin-N-oxide, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel |
| TW352384B (en) * | 1992-03-24 | 1999-02-11 | Hoechst Ag | Sulfonamido- or sulfonamidocarbonylpyridine-2-carboxamides, process for their preparation and their use as pharmaceuticals |
| TW222585B (cs) * | 1992-09-11 | 1994-04-21 | Hoechst Ag | |
| DE4233124A1 (de) * | 1992-10-02 | 1994-04-07 | Hoechst Ag | Acylsulfonamido- und Sulfonamidopyridin-2-carbonsäureester sowie ihre Pyridin-N-oxide, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| US6451816B1 (en) | 1997-06-20 | 2002-09-17 | Klinge Pharma Gmbh | Use of pyridyl alkane, pyridyl alkene and/or pyridyl alkine acid amides in the treatment of tumors or for immunosuppression |
| DE19624704A1 (de) * | 1996-06-20 | 1998-01-08 | Klinge Co Chem Pharm Fab | Neue Pyridylalkansäureamide |
| DE19624659A1 (de) | 1996-06-20 | 1998-01-08 | Klinge Co Chem Pharm Fab | Neue Pyridylalken- und Pyridylalkinsäureamide |
| FR2766187B1 (fr) * | 1997-07-17 | 2000-06-02 | Rhone Poulenc Rorer Sa | Derives de pyrazine, leur preparation et les medicaments les contenant |
| DE19756261A1 (de) | 1997-12-17 | 1999-07-01 | Klinge Co Chem Pharm Fab | Neue arylsubstituierte Pyridylalkan-, alken- und alkincarbonsäureamide |
| DE19756235A1 (de) | 1997-12-17 | 1999-07-01 | Klinge Co Chem Pharm Fab | Neue piperidinylsubstituierte Pyridylalkan- alken- und -alkincarbonsäureamide |
| DE19756212A1 (de) | 1997-12-17 | 1999-07-01 | Klinge Co Chem Pharm Fab | Neue, mit einem cyclischen Imid substituierte Pyridylalkan-, alken- und -alkincarbonsäureamide |
| US6903118B1 (en) | 1997-12-17 | 2005-06-07 | Klinge Pharma Gmbh | Piperazinyl-substituted pyridylalkane, alkene and alkine carboxamides |
| EP1031564A1 (en) | 1999-02-26 | 2000-08-30 | Klinge Pharma GmbH | Inhibitors of cellular nicotinamide mononucleotide formation and their use in cancer therapy |
| DOP2002000332A (es) | 2001-02-14 | 2002-08-30 | Warner Lambert Co | Inhibidores de piridina de metaloproteinasas de la matriz |
| BR0207209A (pt) | 2001-02-14 | 2004-01-27 | Warner Lambert Co | Inibidores de metaloproteinase de matriz de pirimidina |
| DOP2002000333A (es) | 2001-02-14 | 2002-09-30 | Warner Lambert Co | Derivados de acido isoftalico como inhibidores de metaloproteinasas de la matriz |
| US6924276B2 (en) | 2001-09-10 | 2005-08-02 | Warner-Lambert Company | Diacid-substituted heteroaryl derivatives as matrix metalloproteinase inhibitors |
| BR0213233A (pt) | 2001-10-12 | 2005-01-04 | Warner Lambert Co | Alcinos inibidores de metaloproteinase de matriz |
| US6933298B2 (en) | 2001-12-08 | 2005-08-23 | Aventis Pharma Deutschland Gmbh | Pyridine-2,4-dicarboxylic acid diamides and pyrimidine-4,6-dicarboxylic acid diamides and the use thereof for selectively inhibiting collagenases |
| DE10160357A1 (de) * | 2001-12-08 | 2003-06-18 | Aventis Pharma Gmbh | Verwendung von Pyridin-2,4-dicarbonsäurediamiden und Pyrimidin-4,6-dicarbonsäurediamiden zur selektiven Inhibierung von Kollagenasen |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5623987B2 (cs) * | 1972-02-04 | 1981-06-03 | ||
| JPS6052702B2 (ja) | 1976-08-27 | 1985-11-20 | 中外製薬株式会社 | ピリジン誘導体およびその製造方法 |
| JPS57109792A (en) * | 1980-12-26 | 1982-07-08 | Banyu Pharmaceut Co Ltd | Penicillin derivative and salt thereof |
| DE3432094A1 (de) | 1984-08-31 | 1986-03-06 | Hoechst Ag, 6230 Frankfurt | Ester der pyridin-2,4- und -2,5- dicarbonsaeure als arzneimittel zur inhibierung der prolin- und lysinhydroxylase |
| JP2512924B2 (ja) * | 1987-01-21 | 1996-07-03 | 萬有製薬株式会社 | 育毛剤 |
| DE3703962A1 (de) | 1987-02-10 | 1988-08-18 | Hoechst Ag | Pyridin-2,4- und 2,5-dicarbonsaeure-derivate, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen |
| DE3703959A1 (de) | 1987-02-10 | 1988-08-18 | Hoechst Ag | Pyridin-2,4- und 2,5-dicarbonsaeureamide, verfahren zu ihrer herstellung, verwendung derselben sowie arzneimittel auf basis dieser verbindungen |
| DE3703963A1 (de) | 1987-02-10 | 1988-08-18 | Hoechst Ag | Pyridin-2,4- und 2,,5-dicarbonsaeure-derivate, verfahren zu ihrer herstellung, verwendung derselben, sowie arzneimittel auf basis dieser verbindungen |
| JP2600786B2 (ja) * | 1988-04-12 | 1997-04-16 | 萬有製薬株式会社 | 育毛剤 |
| DE3826471A1 (de) | 1988-08-04 | 1990-02-22 | Hoechst Ag | Verbessertes verfahren zur herstellung von n,n'-bis(alkoxyalkyl)-pyridin-2,4-dicarbonsaeurediamiden |
| DE3924093A1 (de) | 1989-07-20 | 1991-02-07 | Hoechst Ag | N,n'-bis(alkoxy-alkyl)-pyridin-2,4-dicarbonsaeurediamide, verfahren zu deren herstellung sowie deren verwendung |
| ZA91291B (en) | 1990-01-16 | 1991-09-25 | Hoechst Ag | Di(nitroxyalkyl)amides of pyridine-2,4-and-2,5-dicarboxylic acids,a process for the preparation thereof,and the use thereof |
-
1990
- 1990-06-28 DE DE4020570A patent/DE4020570A1/de not_active Withdrawn
-
1991
- 1991-06-22 DE DE59102547T patent/DE59102547D1/de not_active Expired - Fee Related
- 1991-06-22 AT AT91110343T patent/ATE110059T1/de not_active IP Right Cessation
- 1991-06-22 EP EP91110343A patent/EP0463592B1/de not_active Expired - Lifetime
- 1991-06-22 DK DK91110343.0T patent/DK0463592T3/da active
- 1991-06-22 ES ES91110343T patent/ES2061118T3/es not_active Expired - Lifetime
- 1991-06-26 IL IL9862991A patent/IL98629A/en not_active IP Right Cessation
- 1991-06-26 MY MYPI91001142A patent/MY107573A/en unknown
- 1991-06-26 NZ NZ238701A patent/NZ238701A/en unknown
- 1991-06-26 FI FI913118A patent/FI101070B/fi active IP Right Grant
- 1991-06-26 CZ CS911959A patent/CZ283782B6/cs not_active IP Right Cessation
- 1991-06-26 EG EG39291A patent/EG19851A/xx active
- 1991-06-27 ZA ZA914958A patent/ZA914958B/xx unknown
- 1991-06-27 JP JP3156562A patent/JPH0832687B2/ja not_active Expired - Lifetime
- 1991-06-27 NO NO912541A patent/NO178026C/no not_active IP Right Cessation
- 1991-06-27 IE IE225391A patent/IE65300B1/en unknown
- 1991-06-27 BR BR919102699A patent/BR9102699A/pt not_active Application Discontinuation
- 1991-06-27 MA MA22469A patent/MA22191A1/fr unknown
- 1991-06-27 YU YU113391A patent/YU113391A/sh unknown
- 1991-06-27 CA CA002045868A patent/CA2045868A1/en not_active Abandoned
- 1991-06-27 HU HU912158A patent/HU214627B/hu not_active IP Right Cessation
- 1991-06-27 PT PT98108A patent/PT98108B/pt not_active IP Right Cessation
- 1991-06-27 AU AU79356/91A patent/AU636990B2/en not_active Ceased
- 1991-06-27 MX MX2641591A patent/MX26415A/es unknown
- 1991-06-27 CN CN91104308A patent/CN1038585C/zh not_active Expired - Fee Related
- 1991-06-28 KR KR1019910010858A patent/KR920000724A/ko not_active Withdrawn
-
1993
- 1993-11-12 LT LTIP1464A patent/LT3918B/lt not_active IP Right Cessation
-
1994
- 1994-10-19 HR HRP-1133/91A patent/HRP940701B1/xx not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EG19851A (en) | Process for preparing of 2,4,- 2,5- substituted pyridine - N - oxides | |
| HUT61153A (en) | Process for producing substituted and heterocyclic phthalides | |
| TW263423B (cs) | ||
| TW245718B (cs) | ||
| ZA887399B (en) | 4-aminopyridine derivatives | |
| ZA914580B (en) | Process for the preparation of dialkyl,pyridine-2,3-dicarboxylates and derivatives thereof from dialkyl dichlorosucciante | |
| IL98125A0 (en) | Process for the preparation of dialkyl pyridine-2,3-dicarboxylates and derivatives thereof from dialkyl dichloromaleate | |
| IL97307A0 (en) | Hexahydrobenz(cd)indoles | |
| GB2204459B (en) | Multi-output feedback amplifier | |
| FR2659652B1 (fr) | Procede de preparation de n-phenyl benzoquinone-imine. | |
| ZA927035B (en) | Process for the microbial oxidation of sulphidic wastes. | |
| PL298749A1 (en) | 4- and/or 5-/sulfo/imido- and /sulfon/amidopyrimidines and their pyridine n-oxides, method of obtaining them and medicines containing such compounds | |
| HU913278D0 (en) | Pirimidine derivatives, fungicides containinmg them, and process for the production of the compounds | |
| ZA891316B (en) | Benzoylurea derivative,process for producing the same,insecticide containing the same,reaction intermediate of the same and process for producing the intermediate | |
| CS394590A3 (en) | Material for sliding surfaces, particularly of bearings | |
| IT218602Z2 (it) | Dispositivo per l'azionamento automatico, particolarmente di ante di armadi, mobili o similari. | |
| ZA914582B (en) | Process for the preparation of dialkyl,pyridine-2,3-dicarboxylates and derivatives thereof from dialkyl dichloromaleate | |
| LV10431A (lv) | 2,4- un 2,5-divaizvietoti piridina N-oksidi to iegusanas panemiens un pielietojums | |
| ZA931555B (en) | Substituted pyridinesulfonamide compound or its salt, process for preparing the same, and herbicide containing the same. | |
| HU913368D0 (en) | Process for the production of sydnonimine derivatives substituted in the 4-position, and of medical preparations containing them |