EE200100394A - Ketoliidsed antibiootikumid - Google Patents

Ketoliidsed antibiootikumid

Info

Publication number
EE200100394A
EE200100394A EEP200100394A EEP200100394A EE200100394A EE 200100394 A EE200100394 A EE 200100394A EE P200100394 A EEP200100394 A EE P200100394A EE P200100394 A EEP200100394 A EE P200100394A EE 200100394 A EE200100394 A EE 200100394A
Authority
EE
Estonia
Prior art keywords
ketolide antibiotics
ketolide
antibiotics
Prior art date
Application number
EEP200100394A
Other languages
English (en)
Estonian (et)
Inventor
Kaneko Takushi
Thomas Mcmillen William
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of EE200100394A publication Critical patent/EE200100394A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/04Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Otolaryngology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Cephalosporin Compounds (AREA)
EEP200100394A 1999-01-27 1999-12-28 Ketoliidsed antibiootikumid EE200100394A (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11734299P 1999-01-27 1999-01-27
PCT/IB1999/002051 WO2000044761A2 (en) 1999-01-27 1999-12-28 Ketolide antibiotics

Publications (1)

Publication Number Publication Date
EE200100394A true EE200100394A (et) 2002-10-15

Family

ID=22372371

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200100394A EE200100394A (et) 1999-01-27 1999-12-28 Ketoliidsed antibiootikumid

Country Status (39)

Country Link
US (1) US6833444B2 (cs)
EP (1) EP1147121B1 (cs)
JP (1) JP3947360B2 (cs)
KR (1) KR20020002380A (cs)
CN (1) CN1342163A (cs)
AP (1) AP2001002222A0 (cs)
AT (1) ATE256694T1 (cs)
AU (1) AU1675400A (cs)
BG (1) BG105730A (cs)
BR (1) BR9916969A (cs)
CA (1) CA2359708C (cs)
CO (1) CO5150229A1 (cs)
CZ (1) CZ20012675A3 (cs)
DE (1) DE69913738T2 (cs)
DK (1) DK1147121T3 (cs)
DZ (1) DZ3000A1 (cs)
EA (1) EA200100623A1 (cs)
EE (1) EE200100394A (cs)
ES (1) ES2212655T3 (cs)
HK (1) HK1042707A1 (cs)
HN (1) HN2000000003A (cs)
HR (1) HRP20010559A2 (cs)
HU (1) HUP0105190A3 (cs)
ID (1) ID30233A (cs)
IL (1) IL144178A0 (cs)
IS (1) IS5984A (cs)
MA (1) MA26717A1 (cs)
NO (1) NO20013680L (cs)
OA (1) OA11753A (cs)
PA (1) PA8489501A1 (cs)
PE (1) PE20001422A1 (cs)
PT (1) PT1147121E (cs)
SI (1) SI1147121T1 (cs)
SK (1) SK10172001A3 (cs)
TN (1) TNSN00007A1 (cs)
TR (1) TR200102128T2 (cs)
UY (1) UY25990A1 (cs)
WO (1) WO2000044761A2 (cs)
ZA (1) ZA200105580B (cs)

Families Citing this family (30)

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AP1060A (en) 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
CA2359708C (en) 1999-01-27 2005-10-25 Pfizer Products Inc. Ketolide antibiotics
US6451768B1 (en) 1999-04-16 2002-09-17 Kosan Biosciences, Inc. Macrolide antiinfective agents
US6458771B1 (en) 1999-04-16 2002-10-01 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
US6590083B1 (en) 1999-04-16 2003-07-08 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
US6514944B2 (en) 1999-04-16 2003-02-04 Kosan Biosciences, Inc. Macrolide antiinfective agents
US6939861B2 (en) 1999-04-16 2005-09-06 Kosan Biosciences, Inc. Amido macrolides
NZ515027A (en) 1999-04-16 2004-01-30 Kosan Biosciences Inc Erythromycin derivatives as antibiotics
OA11945A (en) 1999-05-24 2006-04-13 Pfizer Prod Inc 13-Methyl erythromycin derivatives.
ATE271062T1 (de) 2000-06-30 2004-07-15 Pfizer Prod Inc Makrolid-antibiotika
US20020115621A1 (en) 2000-08-07 2002-08-22 Wei-Gu Su Macrolide antibiotics
CZ20031751A3 (cs) * 2000-12-21 2004-03-17 Glaxo Group Limited Makrolidy
PE20030438A1 (es) * 2001-09-05 2003-07-03 Hokuriku Pharmaceutical Medicamento que comprende un derivado de eritromicina como agente antituberculoso
CA2529817C (en) 2003-03-10 2013-02-12 Optimer Pharmaceuticals, Inc. Novel antibacterial agents
RU2397987C2 (ru) * 2004-07-28 2010-08-27 Рэнбакси Лабораториз Лимитед Кетолидные производные в качестве антибактериальных агентов
JP4111994B1 (ja) 2004-12-21 2008-07-02 ファイザー・プロダクツ・インク マクロライド類
CN103193840A (zh) * 2006-05-01 2013-07-10 大正制药株式会社 大环内酯衍生物
WO2009055557A1 (en) 2007-10-25 2009-04-30 Cempra Pharmaceuticals, Inc. Process for the preparation of macrolide antibacterial agents
WO2010048600A1 (en) 2008-10-24 2010-04-29 Cempra Pharmaceuticals, Inc. Methods for treating resistant diseases using triazole containing macrolides
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
CN108310000A (zh) 2009-09-10 2018-07-24 森普拉制药公司 治疗疟疾、结核病和mac疾病的方法
CA2793884C (en) 2010-03-22 2019-09-10 Cempra Pharmaceuticals, Inc. Crystalline forms of a macrolide, and uses therefor
US9051346B2 (en) 2010-05-20 2015-06-09 Cempra Pharmaceuticals, Inc. Process for preparing triazole-containing ketolide antibiotics
EP2613630A4 (en) 2010-09-10 2014-01-15 Cempra Pharmaceuticals Inc HYDROGEN BOND FOR THE PREPARATION OF FLUOROCHETOLIDES FOR THE TREATMENT OF DISEASES
IN2014DN08939A (cs) 2012-03-27 2015-05-22 Cempra Pharmaceuticals Inc
RU2015138796A (ru) 2013-03-14 2017-04-19 Семпра Фармасьютикалс, Инк. Способы и составы для лечения респираторных заболеваний
WO2014145210A1 (en) 2013-03-15 2014-09-18 Cempra Pharmaceuticals, Inc. Convergent processes for preparing macrolide antibacterial agents
JP6332266B2 (ja) 2013-03-28 2018-05-30 不二製油株式会社 緑豆蛋白ゲル状組成物及びチーズ様食品
CN106518939B (zh) * 2015-09-14 2019-12-31 江苏奥赛康药业有限公司 一种制备Solithromycin化合物的方法
WO2018067663A2 (en) * 2016-10-04 2018-04-12 Biopharmati Sa Ketolides having antibacterial activity

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US4474768A (en) * 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor
US5141926A (en) * 1990-04-18 1992-08-25 Abbott Laboratories Erythromycin derivatives
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AP1060A (en) 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
FR2777282B1 (fr) 1998-04-08 2001-04-20 Hoechst Marion Roussel Inc Nouveaux derives de la 2-fluoro 3-de((2,6-dideoxy 3-c-methyl 3-0-methyl-alpha-l-ribohexopyranosyl) oxyl) 6-o-methyl 3-oxo erythromycine, leur procede de preparation et leur application a la synthese de principes actifs de medicaments
DE69926005T2 (de) 1998-09-22 2006-05-18 Pfizer Products Inc., Groton Carbamat- und carbazatketolidantibiotika
US6100240A (en) * 1998-10-09 2000-08-08 Pfizer Inc Macrolide derivatives
FR2785612A1 (fr) 1998-11-10 2000-05-12 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
OA11670A (en) 1998-11-03 2005-01-12 Pfizer Prod Inc Novel macrolide antibiotics.
FR2786188B1 (fr) 1998-11-24 2002-10-31 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur applicaion comme medicaments
AU6484199A (en) * 1998-12-10 2000-06-26 Pfizer Products Inc. Carbamate and carbazate ketolide antibiotics
CA2359708C (en) 1999-01-27 2005-10-25 Pfizer Products Inc. Ketolide antibiotics
FR2789392B1 (fr) * 1999-02-04 2001-10-05 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
US6458771B1 (en) 1999-04-16 2002-10-01 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
NZ515027A (en) 1999-04-16 2004-01-30 Kosan Biosciences Inc Erythromycin derivatives as antibiotics
US6355620B1 (en) 1999-05-14 2002-03-12 Abbott Laboratories C-2 modified erythromycin derivatives
OA11945A (en) 1999-05-24 2006-04-13 Pfizer Prod Inc 13-Methyl erythromycin derivatives.
EP1114826A3 (en) 1999-12-29 2001-10-31 Pfizer Products Inc. Novel antibacterial and prokinetic macrolides
EP1122261A3 (en) 2000-01-31 2001-09-26 Pfizer Products Inc. 13 and 14-membered antibacterial macrolides
US20020061856A1 (en) 2000-04-24 2002-05-23 Yong-Jin Wu Novel tricyclic erythromycin derivatives
ATE271062T1 (de) 2000-06-30 2004-07-15 Pfizer Prod Inc Makrolid-antibiotika

Also Published As

Publication number Publication date
JP3947360B2 (ja) 2007-07-18
TR200102128T2 (tr) 2001-12-21
EA200100623A1 (ru) 2002-02-28
WO2000044761A2 (en) 2000-08-03
CN1342163A (zh) 2002-03-27
UY25990A1 (es) 2000-09-29
CA2359708C (en) 2005-10-25
MA26717A1 (fr) 2004-12-20
DZ3000A1 (fr) 2004-03-27
HK1042707A1 (zh) 2002-08-23
PA8489501A1 (es) 2000-09-29
DK1147121T3 (da) 2004-04-13
ES2212655T3 (es) 2004-07-16
OA11753A (en) 2005-07-19
BR9916969A (pt) 2001-11-06
AU1675400A (en) 2000-08-18
CO5150229A1 (es) 2002-04-29
SI1147121T1 (en) 2004-04-30
HUP0105190A3 (en) 2003-03-28
NO20013680D0 (no) 2001-07-26
HRP20010559A2 (en) 2002-08-31
ID30233A (id) 2001-11-15
EP1147121A2 (en) 2001-10-24
EP1147121B1 (en) 2003-12-17
WO2000044761A3 (en) 2001-01-04
PT1147121E (pt) 2004-04-30
DE69913738D1 (de) 2004-01-29
HUP0105190A2 (hu) 2002-04-29
JP2002535414A (ja) 2002-10-22
ATE256694T1 (de) 2004-01-15
IS5984A (is) 2001-06-28
US6833444B2 (en) 2004-12-21
SK10172001A3 (sk) 2002-06-04
PE20001422A1 (es) 2000-12-18
HN2000000003A (es) 2001-02-02
US20020156027A1 (en) 2002-10-24
TNSN00007A1 (fr) 2005-11-10
CA2359708A1 (en) 2000-08-03
NO20013680L (no) 2001-09-19
BG105730A (en) 2002-03-29
AP2001002222A0 (en) 2001-09-30
CZ20012675A3 (cs) 2002-04-17
KR20020002380A (ko) 2002-01-09
IL144178A0 (en) 2002-05-23
DE69913738T2 (de) 2004-06-17
ZA200105580B (en) 2003-02-17

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