FR2797263B1 - Oligonucleotide immunostimulant - Google Patents

Oligonucleotide immunostimulant

Info

Publication number
FR2797263B1
FR2797263B1 FR9910378A FR9910378A FR2797263B1 FR 2797263 B1 FR2797263 B1 FR 2797263B1 FR 9910378 A FR9910378 A FR 9910378A FR 9910378 A FR9910378 A FR 9910378A FR 2797263 B1 FR2797263 B1 FR 2797263B1
Authority
FR
France
Prior art keywords
immunostimulant
oligonucleotide
immunostimulant oligonucleotide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9910378A
Other languages
English (en)
Other versions
FR2797263A1 (fr
Inventor
Monique Bachy
Regis Sodoyer
Christine Roques
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Pasteur SA
Original Assignee
Pasteur Merieux Serum et Vaccines SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pasteur Merieux Serum et Vaccines SA filed Critical Pasteur Merieux Serum et Vaccines SA
Priority to FR9910378A priority Critical patent/FR2797263B1/fr
Priority to NZ515957A priority patent/NZ515957A/en
Priority to AU55389/00A priority patent/AU776268B2/en
Priority to PCT/FR2000/001566 priority patent/WO2000075304A1/fr
Priority to EP00940454A priority patent/EP1196558A1/fr
Priority to CA002376634A priority patent/CA2376634A1/fr
Publication of FR2797263A1 publication Critical patent/FR2797263A1/fr
Application granted granted Critical
Publication of FR2797263B1 publication Critical patent/FR2797263B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/117—Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/18—Type of nucleic acid acting by a non-sequence specific mechanism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/30—Chemical structure
    • C12N2310/31—Chemical structure of the backbone
    • C12N2310/315—Phosphorothioates
FR9910378A 1999-06-08 1999-08-06 Oligonucleotide immunostimulant Expired - Fee Related FR2797263B1 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
FR9910378A FR2797263B1 (fr) 1999-08-06 1999-08-06 Oligonucleotide immunostimulant
NZ515957A NZ515957A (en) 1999-06-08 2000-06-08 Immunostimulant oligonucleotide
AU55389/00A AU776268B2 (en) 1999-06-08 2000-06-08 Immunostimulant oligonucleotide
PCT/FR2000/001566 WO2000075304A1 (fr) 1999-06-08 2000-06-08 Oligonucleotide immunostimulant
EP00940454A EP1196558A1 (fr) 1999-06-08 2000-06-08 Oligonucleotide immunostimulant
CA002376634A CA2376634A1 (fr) 1999-06-08 2000-06-08 Oligonucleotide immunostimulant

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9910378A FR2797263B1 (fr) 1999-08-06 1999-08-06 Oligonucleotide immunostimulant

Publications (2)

Publication Number Publication Date
FR2797263A1 FR2797263A1 (fr) 2001-02-09
FR2797263B1 true FR2797263B1 (fr) 2003-09-19

Family

ID=9549062

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9910378A Expired - Fee Related FR2797263B1 (fr) 1999-06-08 1999-08-06 Oligonucleotide immunostimulant

Country Status (1)

Country Link
FR (1) FR2797263B1 (fr)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995026204A1 (fr) * 1994-03-25 1995-10-05 Isis Pharmaceuticals, Inc. Stimulation immunitaire par des analogues d'oligonucleotides de phosphorothioate
CA2281838A1 (fr) * 1997-02-28 1998-09-03 University Of Iowa Research Foundation Utilisation d'acides nucleiques contenant des dinucleotides cpg non methyles dans le traitement des troubles associes aux lipopolysaccharides

Also Published As

Publication number Publication date
FR2797263A1 (fr) 2001-02-09

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Legal Events

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CD Change of name or company name
CD Change of name or company name
ST Notification of lapse

Effective date: 20090430