ZA200105580B - Ketolide antibiotics. - Google Patents
Ketolide antibiotics. Download PDFInfo
- Publication number
- ZA200105580B ZA200105580B ZA200105580A ZA200105580A ZA200105580B ZA 200105580 B ZA200105580 B ZA 200105580B ZA 200105580 A ZA200105580 A ZA 200105580A ZA 200105580 A ZA200105580 A ZA 200105580A ZA 200105580 B ZA200105580 B ZA 200105580B
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- ZA
- South Africa
- Prior art keywords
- alkyl
- aryl
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- independently selected
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- 239000003835 ketolide antibiotic agent Substances 0.000 title description 2
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Biochemistry (AREA)
- Gynecology & Obstetrics (AREA)
- Urology & Nephrology (AREA)
- Pregnancy & Childbirth (AREA)
- Ophthalmology & Optometry (AREA)
- Dermatology (AREA)
- Otolaryngology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11734299P | 1999-01-27 | 1999-01-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200105580B true ZA200105580B (en) | 2003-02-17 |
Family
ID=22372371
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200105580A ZA200105580B (en) | 1999-01-27 | 2001-07-06 | Ketolide antibiotics. |
Country Status (39)
| Country | Link |
|---|---|
| US (1) | US6833444B2 (cs) |
| EP (1) | EP1147121B1 (cs) |
| JP (1) | JP3947360B2 (cs) |
| KR (1) | KR20020002380A (cs) |
| CN (1) | CN1342163A (cs) |
| AP (1) | AP2001002222A0 (cs) |
| AT (1) | ATE256694T1 (cs) |
| AU (1) | AU1675400A (cs) |
| BG (1) | BG105730A (cs) |
| BR (1) | BR9916969A (cs) |
| CA (1) | CA2359708C (cs) |
| CO (1) | CO5150229A1 (cs) |
| CZ (1) | CZ20012675A3 (cs) |
| DE (1) | DE69913738T2 (cs) |
| DK (1) | DK1147121T3 (cs) |
| DZ (1) | DZ3000A1 (cs) |
| EA (1) | EA200100623A1 (cs) |
| EE (1) | EE200100394A (cs) |
| ES (1) | ES2212655T3 (cs) |
| HK (1) | HK1042707A1 (cs) |
| HN (1) | HN2000000003A (cs) |
| HR (1) | HRP20010559A2 (cs) |
| HU (1) | HUP0105190A3 (cs) |
| ID (1) | ID30233A (cs) |
| IL (1) | IL144178A0 (cs) |
| IS (1) | IS5984A (cs) |
| MA (1) | MA26717A1 (cs) |
| NO (1) | NO20013680L (cs) |
| OA (1) | OA11753A (cs) |
| PA (1) | PA8489501A1 (cs) |
| PE (1) | PE20001422A1 (cs) |
| PT (1) | PT1147121E (cs) |
| SI (1) | SI1147121T1 (cs) |
| SK (1) | SK10172001A3 (cs) |
| TN (1) | TNSN00007A1 (cs) |
| TR (1) | TR200102128T2 (cs) |
| UY (1) | UY25990A1 (cs) |
| WO (1) | WO2000044761A2 (cs) |
| ZA (1) | ZA200105580B (cs) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AP1060A (en) | 1998-01-02 | 2002-04-23 | Pfizer Prod Inc | Novel erythromycin derivatives. |
| WO2000044761A2 (en) | 1999-01-27 | 2000-08-03 | Pfizer Products Inc. | Ketolide antibiotics |
| US6514944B2 (en) | 1999-04-16 | 2003-02-04 | Kosan Biosciences, Inc. | Macrolide antiinfective agents |
| US6939861B2 (en) | 1999-04-16 | 2005-09-06 | Kosan Biosciences, Inc. | Amido macrolides |
| MXPA01010521A (es) | 1999-04-16 | 2003-08-19 | Johnson & Johnson | Antibacteriales de cetolidos. |
| US6451768B1 (en) | 1999-04-16 | 2002-09-17 | Kosan Biosciences, Inc. | Macrolide antiinfective agents |
| US6590083B1 (en) | 1999-04-16 | 2003-07-08 | Ortho-Mcneil Pharmaceutical, Inc. | Ketolide antibacterials |
| KR100710605B1 (ko) | 1999-04-16 | 2007-04-24 | 코산 바이오사이언시즈, 인코포레이티드 | 매크롤라이드 항감염제 |
| HK1045523A1 (zh) | 1999-05-24 | 2002-11-29 | 辉瑞产品公司 | 13-甲基红霉素衍生物 |
| PT1167376E (pt) | 2000-06-30 | 2004-09-30 | Pfizer Prod Inc | Antibioticos macrolidos |
| US20020115621A1 (en) | 2000-08-07 | 2002-08-22 | Wei-Gu Su | Macrolide antibiotics |
| IL156561A0 (en) * | 2000-12-21 | 2004-01-04 | Glaxo Group Ltd | Macrolide antibiotics |
| PE20030438A1 (es) * | 2001-09-05 | 2003-07-03 | Hokuriku Pharmaceutical | Medicamento que comprende un derivado de eritromicina como agente antituberculoso |
| ES2552682T3 (es) | 2003-03-10 | 2015-12-01 | Merck Sharp & Dohme Corp. | Agentes antibacterianos novedosos |
| RU2397987C2 (ru) * | 2004-07-28 | 2010-08-27 | Рэнбакси Лабораториз Лимитед | Кетолидные производные в качестве антибактериальных агентов |
| HRP20100253T1 (hr) | 2004-12-21 | 2010-06-30 | Pfizer Products Inc. | Makrolidi |
| CN103193840A (zh) * | 2006-05-01 | 2013-07-10 | 大正制药株式会社 | 大环内酯衍生物 |
| EP2214484A4 (en) | 2007-10-25 | 2013-01-02 | Cempra Pharmaceuticals Inc | PROCESS FOR PREPARING ANTIBACTERIAL MAKROLIDE AGENTS |
| WO2010048601A1 (en) | 2008-10-24 | 2010-04-29 | Cempra Pharmaceuticals, Inc. | Biodefenses using triazole-containing macrolides |
| US9937194B1 (en) | 2009-06-12 | 2018-04-10 | Cempra Pharmaceuticals, Inc. | Compounds and methods for treating inflammatory diseases |
| CN108310000A (zh) | 2009-09-10 | 2018-07-24 | 森普拉制药公司 | 治疗疟疾、结核病和mac疾病的方法 |
| CN103080122A (zh) | 2010-03-22 | 2013-05-01 | 森普拉制药公司 | 大环内脂的结晶形式及其用途 |
| BR112012029586A2 (pt) | 2010-05-20 | 2016-08-02 | Cempra Pharmaceuticals Inc | processos para preparar macrolídeos e cetolídeos e intermediários dos mesmos |
| US9815863B2 (en) | 2010-09-10 | 2017-11-14 | Cempra Pharmaceuticals, Inc. | Hydrogen bond forming fluoro ketolides for treating diseases |
| MX2014011537A (es) | 2012-03-27 | 2015-02-10 | Cempra Pharmaceuticals Inc | Formulaciones parenterales para la administracion de antibioticos macrolidos. |
| JP6426696B2 (ja) | 2013-03-14 | 2018-11-21 | センプラ ファーマシューティカルズ，インコーポレイテッド | 呼吸器疾患の治療のための方法および製剤 |
| EP2968384A4 (en) | 2013-03-15 | 2017-02-15 | Cempra Pharmaceuticals, Inc. | Convergent processes for preparing macrolide antibacterial agents |
| JP6332266B2 (ja) | 2013-03-28 | 2018-05-30 | 不二製油株式会社 | 緑豆蛋白ゲル状組成物及びチーズ様食品 |
| CN106518939B (zh) * | 2015-09-14 | 2019-12-31 | 江苏奥赛康药业有限公司 | 一种制备Solithromycin化合物的方法 |
| WO2018067663A2 (en) * | 2016-10-04 | 2018-04-12 | Biopharmati Sa | Ketolides having antibacterial activity |
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| SI8110592A8 (en) | 1981-03-06 | 1996-06-30 | Pliva Pharm & Chem Works | Process for preparing of n-methyl-11-aza-10-deoxo-10-dihydroerythromycine a and derivatives thereof |
| US4474768A (en) | 1982-07-19 | 1984-10-02 | Pfizer Inc. | N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor |
| US5141926A (en) | 1990-04-18 | 1992-08-25 | Abbott Laboratories | Erythromycin derivatives |
| IL99995A (en) | 1990-11-21 | 1997-11-20 | Roussel Uclaf | Erythromycin derivatives, their preparation and pharmaceutical compositions containing them |
| US5527780A (en) | 1992-11-05 | 1996-06-18 | Roussel Uclaf | Erythromycin derivatives |
| FR2697524B1 (fr) | 1992-11-05 | 1994-12-23 | Roussel Uclaf | Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments. |
| FR2719587B1 (fr) * | 1994-05-03 | 1996-07-12 | Roussel Uclaf | Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments. |
| FR2727969B1 (fr) * | 1994-12-09 | 1997-01-17 | Roussel Uclaf | Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments |
| US5747466A (en) | 1995-11-08 | 1998-05-05 | Abbott Laboratories | 3-deoxy-3-descladinose derivatives of erythromycins A and B |
| FR2742757B1 (fr) * | 1995-12-22 | 1998-01-30 | Roussel Uclaf | Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments |
| FR2745290B1 (fr) | 1996-02-28 | 1998-04-03 | Roussel Uclaf | Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments |
| FR2748746B1 (fr) | 1996-05-14 | 1998-08-14 | Hoechst Marion Roussel Inc | Nouveau procede d'isomerisation du radical methyle en 10 de derives de l'erythromycine |
| JP4173551B2 (ja) | 1996-07-05 | 2008-10-29 | バイオティカ テクノロジー リミティド | 新規エリスロマイシン及びその製造方法 |
| FR2751656B1 (fr) | 1996-07-24 | 1998-10-16 | Hoechst Marion Roussel Inc | Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments |
| UA51730C2 (uk) | 1996-09-04 | 2002-12-16 | Ебботт Лабораторіз | 6-o-заміщені кетоліди з антибактеріальною активністю, спосіб їх одержання (варіанти), фармацевтична композиція та спосіб регулювання бактеріальної інфекції у ссавців |
| FR2757168B1 (fr) | 1996-12-12 | 1999-06-11 | Hoechst Marion Roussel Inc | Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments |
| FR2760017B1 (fr) | 1997-02-27 | 1999-04-30 | Hoechst Marion Roussel Inc | Nouveaux derives de l'erytromycine, leur procede de preparation et leur application comme medicaments |
| AU4472897A (en) | 1997-03-10 | 1998-09-29 | Taisho Pharmaceutical Co., Ltd. | Erythromycin a derivatives |
| US20020025937A1 (en) | 2000-03-20 | 2002-02-28 | Yong-Jin Wu | 9-oxime erythromycin derivatives |
| ZA987689B (en) | 1997-09-02 | 1999-02-24 | Abbott Lab | 3-descladinose 6-O substituted erythromycin derivatives |
| WO1999021869A1 (en) | 1997-10-29 | 1999-05-06 | Taisho Pharmaceutical Co., Ltd. | Erythromycin a, 11,12-carbamate derivatives |
| HN1998000159A (es) | 1997-10-29 | 1999-02-09 | Monsanto Co | Derivados de 9- amino - 3 ceto eritromicina |
| FR2771008B1 (fr) * | 1997-11-17 | 2000-04-28 | Hoechst Marion Roussel Inc | Utilisation des ketolides pour la preparation de compositions pharmaceutiques destinees a prevenir les complications thrombotiques arterielles liees a l'atherosclerose |
| AU1390699A (en) | 1997-11-17 | 1999-06-07 | Imarx Pharmaceutical Corp. | A method of increasing nucleic acid synthesis with ultrasound |
| AP1060A (en) | 1998-01-02 | 2002-04-23 | Pfizer Prod Inc | Novel erythromycin derivatives. |
| FR2777282B1 (fr) | 1998-04-08 | 2001-04-20 | Hoechst Marion Roussel Inc | Nouveaux derives de la 2-fluoro 3-de((2,6-dideoxy 3-c-methyl 3-0-methyl-alpha-l-ribohexopyranosyl) oxyl) 6-o-methyl 3-oxo erythromycine, leur procede de preparation et leur application a la synthese de principes actifs de medicaments |
| ATE298761T1 (de) | 1998-09-22 | 2005-07-15 | Pfizer Prod Inc | Carbamat- und carbazatketolidantibiotika |
| US6100240A (en) | 1998-10-09 | 2000-08-08 | Pfizer Inc | Macrolide derivatives |
| FR2785612A1 (fr) * | 1998-11-10 | 2000-05-12 | Hoechst Marion Roussel Inc | Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments |
| KR20010083944A (ko) | 1998-11-03 | 2001-09-03 | 실버스타인 아써 에이. | 신규 마크롤라이드 항생물질 |
| FR2786188B1 (fr) | 1998-11-24 | 2002-10-31 | Hoechst Marion Roussel Inc | Nouveaux derives de l'erythromycine, leur procede de preparation et leur applicaion comme medicaments |
| WO2000034297A1 (en) | 1998-12-10 | 2000-06-15 | Pfizer Products Inc. | Carbamate and carbazate ketolide antibiotics |
| WO2000044761A2 (en) | 1999-01-27 | 2000-08-03 | Pfizer Products Inc. | Ketolide antibiotics |
| FR2789392B1 (fr) | 1999-02-04 | 2001-10-05 | Hoechst Marion Roussel Inc | Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments |
| KR100710605B1 (ko) | 1999-04-16 | 2007-04-24 | 코산 바이오사이언시즈, 인코포레이티드 | 매크롤라이드 항감염제 |
| MXPA01010521A (es) | 1999-04-16 | 2003-08-19 | Johnson & Johnson | Antibacteriales de cetolidos. |
| US6355620B1 (en) | 1999-05-14 | 2002-03-12 | Abbott Laboratories | C-2 modified erythromycin derivatives |
| HK1045523A1 (zh) | 1999-05-24 | 2002-11-29 | 辉瑞产品公司 | 13-甲基红霉素衍生物 |
| EP1114826A3 (en) | 1999-12-29 | 2001-10-31 | Pfizer Products Inc. | Novel antibacterial and prokinetic macrolides |
| EP1122261A3 (en) | 2000-01-31 | 2001-09-26 | Pfizer Products Inc. | 13 and 14-membered antibacterial macrolides |
| US20020061856A1 (en) | 2000-04-24 | 2002-05-23 | Yong-Jin Wu | Novel tricyclic erythromycin derivatives |
| PT1167376E (pt) | 2000-06-30 | 2004-09-30 | Pfizer Prod Inc | Antibioticos macrolidos |
-
1999
- 1999-12-28 WO PCT/IB1999/002051 patent/WO2000044761A2/en not_active Ceased
- 1999-12-28 DE DE69913738T patent/DE69913738T2/de not_active Expired - Lifetime
- 1999-12-28 OA OA1200100191A patent/OA11753A/en unknown
- 1999-12-28 AT AT99959627T patent/ATE256694T1/de not_active IP Right Cessation
- 1999-12-28 AU AU16754/00A patent/AU1675400A/en not_active Abandoned
- 1999-12-28 ES ES99959627T patent/ES2212655T3/es not_active Expired - Lifetime
- 1999-12-28 SK SK1017-2001A patent/SK10172001A3/sk unknown
- 1999-12-28 CZ CZ20012675A patent/CZ20012675A3/cs unknown
- 1999-12-28 HU HU0105190A patent/HUP0105190A3/hu unknown
- 1999-12-28 JP JP2000596017A patent/JP3947360B2/ja not_active Expired - Fee Related
- 1999-12-28 HR HR20010559A patent/HRP20010559A2/hr not_active Application Discontinuation
- 1999-12-28 EP EP99959627A patent/EP1147121B1/en not_active Expired - Lifetime
- 1999-12-28 ID IDW00200101637A patent/ID30233A/id unknown
- 1999-12-28 EE EEP200100394A patent/EE200100394A/xx unknown
- 1999-12-28 EA EA200100623A patent/EA200100623A1/ru unknown
- 1999-12-28 BR BR9916969-0A patent/BR9916969A/pt not_active Application Discontinuation
- 1999-12-28 IL IL14417899A patent/IL144178A0/xx unknown
- 1999-12-28 DK DK99959627T patent/DK1147121T3/da active
- 1999-12-28 CN CN99815909A patent/CN1342163A/zh active Pending
- 1999-12-28 KR KR1020017009382A patent/KR20020002380A/ko not_active Ceased
- 1999-12-28 SI SI9930486T patent/SI1147121T1/xx unknown
- 1999-12-28 AP APAP/P/2001/002222A patent/AP2001002222A0/en unknown
- 1999-12-28 HK HK02104131.0A patent/HK1042707A1/zh unknown
- 1999-12-28 TR TR2001/02128T patent/TR200102128T2/xx unknown
- 1999-12-28 CA CA002359708A patent/CA2359708C/en not_active Expired - Fee Related
- 1999-12-28 PT PT99959627T patent/PT1147121E/pt unknown
-
2000
- 2000-01-05 DZ DZ000002A patent/DZ3000A1/xx active
- 2000-01-05 TN TNTNSN00007A patent/TNSN00007A1/fr unknown
- 2000-01-06 HN HN2000000003A patent/HN2000000003A/es unknown
- 2000-01-06 PE PE2000000013A patent/PE20001422A1/es not_active Application Discontinuation
- 2000-01-06 PA PA20008489501A patent/PA8489501A1/es unknown
- 2000-01-06 MA MA25883A patent/MA26717A1/fr unknown
- 2000-01-21 CO CO00003460A patent/CO5150229A1/es unknown
- 2000-01-27 UY UY25990A patent/UY25990A1/es unknown
-
2001
- 2001-06-28 IS IS5984A patent/IS5984A/is unknown
- 2001-07-06 ZA ZA200105580A patent/ZA200105580B/en unknown
- 2001-07-25 BG BG105730A patent/BG105730A/xx unknown
- 2001-07-26 NO NO20013680A patent/NO20013680L/no not_active Application Discontinuation
-
2002
- 2002-04-05 US US10/116,969 patent/US6833444B2/en not_active Expired - Fee Related
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