EE05263B1 - IL-18 inhibiitorite kasutamine kesknrvissteemi kahjustuste raviks v?i ennetamiseks - Google Patents
IL-18 inhibiitorite kasutamine kesknrvissteemi kahjustuste raviks v?i ennetamiseksInfo
- Publication number
- EE05263B1 EE05263B1 EEP200300582A EEP200300582A EE05263B1 EE 05263 B1 EE05263 B1 EE 05263B1 EE P200300582 A EEP200300582 A EE P200300582A EE P200300582 A EEP200300582 A EE P200300582A EE 05263 B1 EE05263 B1 EE 05263B1
- Authority
- EE
- Estonia
- Prior art keywords
- focuses
- inhibitors
- prevention
- treatment
- systemic damage
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
- 230000009885 systemic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Rheumatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01112067 | 2001-05-25 | ||
| PCT/EP2002/005666 WO2002096456A1 (en) | 2001-05-25 | 2002-05-23 | Use of il-18 inhibitors for treating or preventing cns injuries |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EE200300582A EE200300582A (et) | 2004-02-16 |
| EE05263B1 true EE05263B1 (et) | 2010-02-15 |
Family
ID=8177454
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EEP200300582A EE05263B1 (et) | 2001-05-25 | 2002-05-23 | IL-18 inhibiitorite kasutamine kesknrvissteemi kahjustuste raviks v?i ennetamiseks |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US7655616B2 (no) |
| EP (1) | EP1390070B1 (no) |
| JP (1) | JP4344142B2 (no) |
| KR (1) | KR20040030625A (no) |
| CN (1) | CN1305529C (no) |
| AU (1) | AU2002314103B2 (no) |
| BG (1) | BG66395B1 (no) |
| BR (1) | BR0210007A (no) |
| CA (1) | CA2445664C (no) |
| CY (1) | CY1119190T1 (no) |
| CZ (1) | CZ307321B6 (no) |
| DK (1) | DK1390070T3 (no) |
| EA (1) | EA006744B1 (no) |
| EE (1) | EE05263B1 (no) |
| ES (1) | ES2617084T3 (no) |
| HK (1) | HK1069762A1 (no) |
| HR (1) | HRP20030842B1 (no) |
| HU (1) | HU230294B1 (no) |
| IL (2) | IL159014A0 (no) |
| LT (1) | LT1390070T (no) |
| ME (1) | ME00550B (no) |
| MX (1) | MXPA03010743A (no) |
| NO (1) | NO331882B1 (no) |
| PL (1) | PL216228B1 (no) |
| PT (1) | PT1390070T (no) |
| RS (1) | RS56006B1 (no) |
| SK (1) | SK288413B6 (no) |
| UA (1) | UA80396C2 (no) |
| WO (1) | WO2002096456A1 (no) |
| ZA (1) | ZA200308172B (no) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080076708A1 (en) | 2003-05-13 | 2008-03-27 | Valter Altarocca | Active Variants of the Il-18 Binding Protein and Medical Uses Thereof |
| EP1780542A4 (en) * | 2004-06-30 | 2008-05-14 | Atsuo Sekiyama | AGENT INDICATING A NON-INFLAMMATORY RESPONSE TO A STRESS AND USE THEREOF |
| WO2006128911A2 (en) * | 2005-06-03 | 2006-12-07 | Laboratoires Serono S.A. | Use of il-18bp isoforms for the treatment and/or prevention of neurological inflammatory diseases |
| SI2267024T1 (sl) | 2005-06-03 | 2012-09-28 | Ares Trading Sa | Proizvodnja rekombinantnega IL-18 vezavnega proteina |
| ES2375831T3 (es) | 2005-06-10 | 2012-03-06 | Ares Trading S.A. | Procedimiento para la purificación de prote�?nas de unión a il-18. |
| US8685400B2 (en) * | 2007-07-30 | 2014-04-01 | University Of Miami | Modulating inflammasome activity and inflammation in the central nervous system |
| LT3041864T (lt) | 2013-09-05 | 2021-10-11 | Ab2 Bio Sa | Il-18 surišantis baltymas (il-18p) uždegiminių ligų atvejais |
| WO2016139297A1 (en) | 2015-03-05 | 2016-09-09 | Ab2 Bio Sa | Il-18 binding protein (il-18bp) and antibodies in inflammatory diseases |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0873453A (ja) * | 1994-09-02 | 1996-03-19 | Otsuka Pharmaceut Co Ltd | サイトカイン阻害剤 |
| IL121860A0 (en) * | 1997-08-14 | 1998-02-22 | Yeda Res & Dev | Interleukin-18 binding proteins their preparation and use |
| ES2244178T3 (es) * | 1998-03-09 | 2005-12-01 | Vertex Pharmaceuticals Incorporated | Derivados de 1,2-diazepan como inhibidores de la enzima convertidora de interleuquina-1 beta. |
| CA2276216A1 (en) * | 1998-06-24 | 1999-12-24 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | An artificial peptide capable of neutralizing the biological activity of interleukin-18 |
| SK287761B6 (en) * | 2000-05-05 | 2011-09-05 | Applied Research Systems Ars Holding N. V. | Use of IL-18 inhibitor, use of an expressing vector which contains a sequence encoding IL-18 inhibitor, use of the vector for induction and/or amplifying endogenic production of IL-18 inhibitor in a cell and use a cell with production of IL-18 inhibitor |
| ATE277608T1 (de) * | 2000-06-23 | 2004-10-15 | Yissum Res Dev Co | 2-arachidonylglycerol, ein hemmer des tumor nekrose faktors -alfa und neuroprotektor des gehirns bei geschlossenen kopfverletzungen |
| AU2002224417A1 (en) * | 2000-10-18 | 2002-04-29 | Immunex Corporation | Methods for treating il-18 mediated disorders |
| US6671553B1 (en) * | 2001-05-23 | 2003-12-30 | Pacesetter, Inc. | Implantable cardiac lead having terminating connector strain relief and method of manufacture |
-
2002
- 2002-05-23 IL IL15901402A patent/IL159014A0/xx unknown
- 2002-05-23 RS YU89403A patent/RS56006B1/sr unknown
- 2002-05-23 ME MEP-2008-618A patent/ME00550B/me unknown
- 2002-05-23 CZ CZ2003-3268A patent/CZ307321B6/cs not_active IP Right Cessation
- 2002-05-23 EP EP02740641.2A patent/EP1390070B1/en not_active Expired - Lifetime
- 2002-05-23 PT PT2740641T patent/PT1390070T/pt unknown
- 2002-05-23 WO PCT/EP2002/005666 patent/WO2002096456A1/en active IP Right Grant
- 2002-05-23 EA EA200301299A patent/EA006744B1/ru not_active IP Right Cessation
- 2002-05-23 PL PL367545A patent/PL216228B1/pl unknown
- 2002-05-23 AU AU2002314103A patent/AU2002314103B2/en not_active Expired
- 2002-05-23 CA CA2445664A patent/CA2445664C/en not_active Expired - Lifetime
- 2002-05-23 CN CNB028147510A patent/CN1305529C/zh not_active Expired - Lifetime
- 2002-05-23 LT LTEP02740641.2T patent/LT1390070T/lt unknown
- 2002-05-23 DK DK02740641.2T patent/DK1390070T3/en active
- 2002-05-23 UA UA20031212328A patent/UA80396C2/uk unknown
- 2002-05-23 ES ES02740641.2T patent/ES2617084T3/es not_active Expired - Lifetime
- 2002-05-23 SK SK1603-2003A patent/SK288413B6/sk not_active IP Right Cessation
- 2002-05-23 MX MXPA03010743A patent/MXPA03010743A/es active IP Right Grant
- 2002-05-23 EE EEP200300582A patent/EE05263B1/xx unknown
- 2002-05-23 BR BR0210007-0A patent/BR0210007A/pt not_active Application Discontinuation
- 2002-05-23 KR KR10-2003-7015310A patent/KR20040030625A/ko active Search and Examination
- 2002-05-23 HU HU0304067A patent/HU230294B1/hu unknown
- 2002-05-23 JP JP2002592965A patent/JP4344142B2/ja not_active Expired - Lifetime
- 2002-05-23 US US10/478,614 patent/US7655616B2/en not_active Expired - Lifetime
-
2003
- 2003-10-17 HR HRP20030842AA patent/HRP20030842B1/hr not_active IP Right Cessation
- 2003-10-21 ZA ZA200308172A patent/ZA200308172B/xx unknown
- 2003-11-20 NO NO20035160A patent/NO331882B1/no not_active IP Right Cessation
- 2003-11-23 IL IL159014A patent/IL159014A/en active IP Right Grant
- 2003-12-15 BG BG108451A patent/BG66395B1/bg unknown
-
2004
- 2004-12-31 HK HK04110391A patent/HK1069762A1/xx not_active IP Right Cessation
-
2017
- 2017-05-08 CY CY20171100494T patent/CY1119190T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CY2015028I2 (el) | Ενας αναστολεας ν-ακυλοσφιγγοσινο γλυκοζυλοτρανσφερασης | |
| AR028253A1 (es) | Inhibidores de la glucogeno fosforilasa | |
| ATE484496T1 (de) | Metalloproteinaseinhibitoren | |
| EE200300439A (et) | Metalloproteinaasi inhibiitorid | |
| DE60234125D1 (de) | E inhibitoren | |
| PT1370553E (pt) | Inibidores de rhoquinase | |
| IS2529B (is) | Nýjar spírótrísýklískar afleiður og notkun þeirra sem fosfódíesterasa-7-hindrar | |
| DE60218138D1 (de) | Rho-kinase inhibitoren | |
| IS7138A (is) | Alkýn-arýl fosfódíesterasa-4 hindrar | |
| NO20024528L (no) | Proteaseinhibitor, farmasoytisk sammensetning og anvendelse av forbindelsen | |
| EE200300450A (et) | Metalloproteinaasi inhibiitorid | |
| NO20025307L (no) | Anvendelse av IL-18 inhibitorer til behandling og/eller forebygging av aterosklerose | |
| DK1272488T3 (da) | Tri-aryl-substitueret ethan-PDE4-inhibitorer | |
| FI20011370A (fi) | Biotunnistusmenetelmä ja sitä hyödyntävä laite | |
| EE05263B1 (et) | IL-18 inhibiitorite kasutamine kesknrvissteemi kahjustuste raviks v?i ennetamiseks | |
| SE0301854L (sv) | Antiigensättningsbehandling | |
| NO20004920D0 (no) | Anvendelse av proteaseinhibitorer for behandling av hudskader | |
| NO20040370L (no) | Anvendelse av IL-18-inhibitorer i hypersensitivitetslidelser. | |
| NO20034785L (no) | Farmas degree ytiske kombinasjoner basert på pyridoindolonderivater og anticancer-midler | |
| DE60205008D1 (de) | Kettelverfahren und -vorrichtung | |
| NO20033160D0 (no) | Anordning for behandling av gravann | |
| GB0119460D0 (en) | The use of inhibitors of the renin-angiotensin system | |
| FI20011542A (fi) | Urosognaasigeenin monistuman käyttö | |
| ITTO20020476A1 (it) | Composti pironici e loro utilizzo. | |
| FR2824262B1 (fr) | Le slip preservatif |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HE1A | Change of address | ||
| KB4A | Valid patent at the end of a year |
Effective date: 20101231 |
|
| HC1A | Change of owner name |