EE03520B1 - Terminaalseid karboksüül- või tetrasolüülrühmi sisaldavad dialküüleetrid - Google Patents

Terminaalseid karboksüül- või tetrasolüülrühmi sisaldavad dialküüleetrid

Info

Publication number
EE03520B1
EE03520B1 EE9700375A EE9700375A EE03520B1 EE 03520 B1 EE03520 B1 EE 03520B1 EE 9700375 A EE9700375 A EE 9700375A EE 9700375 A EE9700375 A EE 9700375A EE 03520 B1 EE03520 B1 EE 03520B1
Authority
EE
Estonia
Prior art keywords
dialkyl ethers
terminal carboxyl
containing terminal
ethers containing
tetrazolyl groups
Prior art date
Application number
EE9700375A
Other languages
English (en)
Estonian (et)
Other versions
EE9700375A (et
Inventor
Larry Bisgaier Charles
Leroy Creger Paul
Robert Saltiel Alan
Rae Tafuri Sherrie
Original Assignee
Warner-Lambert Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner-Lambert Company filed Critical Warner-Lambert Company
Publication of EE9700375A publication Critical patent/EE9700375A/xx
Publication of EE03520B1 publication Critical patent/EE03520B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
    • C07C47/277—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/28—Saturated compounds having —CHO groups bound to carbon atoms of rings other than six—membered aromatic rings
    • C07C47/37—Saturated compounds having —CHO groups bound to carbon atoms of rings other than six—membered aromatic rings containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235—Saturated compounds containing more than one carboxyl group
    • C07C59/305—Saturated compounds containing more than one carboxyl group containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235—Saturated compounds containing more than one carboxyl group
    • C07C59/305—Saturated compounds containing more than one carboxyl group containing ether groups, groups, groups, or groups
    • C07C59/315—Saturated compounds containing more than one carboxyl group containing ether groups, groups, groups, or groups containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235—Saturated compounds containing more than one carboxyl group
    • C07C59/347—Saturated compounds containing more than one carboxyl group containing keto groups
    • C07C59/353—Saturated compounds containing more than one carboxyl group containing keto groups containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
    • C07C69/708—Ethers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pigments, Carbon Blacks, Or Wood Stains (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Detergent Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Absorbent Articles And Supports Therefor (AREA)
  • Dental Preparations (AREA)
EE9700375A 1995-03-24 1996-02-05 Terminaalseid karboksüül- või tetrasolüülrühmi sisaldavad dialküüleetrid EE03520B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/409,780 US5648387A (en) 1995-03-24 1995-03-24 Carboxyalkylethers, formulations, and treatment of vascular diseases
PCT/US1996/001639 WO1996030328A1 (en) 1995-03-24 1996-02-05 Terminal carboxy or tetrazole groups containing dialkyl ethers

Publications (2)

Publication Number Publication Date
EE9700375A EE9700375A (et) 1998-06-15
EE03520B1 true EE03520B1 (et) 2001-10-15

Family

ID=23621941

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9700375A EE03520B1 (et) 1995-03-24 1996-02-05 Terminaalseid karboksüül- või tetrasolüülrühmi sisaldavad dialküüleetrid

Country Status (27)

Country Link
US (4) US5648387A (no)
EP (1) EP0820428B1 (no)
JP (1) JP3885115B2 (no)
KR (1) KR100408612B1 (no)
CN (1) CN1100747C (no)
AT (1) ATE192732T1 (no)
AU (1) AU692359B2 (no)
BG (1) BG63534B1 (no)
CA (1) CA2215233C (no)
CZ (1) CZ289556B6 (no)
DE (1) DE69608268T2 (no)
DK (1) DK0820428T3 (no)
EE (1) EE03520B1 (no)
ES (1) ES2148733T3 (no)
FI (1) FI973713A (no)
GR (1) GR3034109T3 (no)
HK (1) HK1009438A1 (no)
HU (1) HUP9801825A3 (no)
NO (1) NO307878B1 (no)
NZ (1) NZ302170A (no)
PL (1) PL181673B1 (no)
PT (1) PT820428E (no)
RU (1) RU2191772C2 (no)
SK (1) SK282897B6 (no)
UA (1) UA46020C2 (no)
WO (1) WO1996030328A1 (no)
ZA (1) ZA962275B (no)

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KR20010033017A (ko) * 1997-12-12 2001-04-25 로즈 암스트롱, 크리스틴 에이. 트러트웨인 과지질혈증 치료제인 스타틴-ＬＰ(ａ) 억제제의 병용 제제
EP1481962A1 (en) * 1997-12-12 2004-12-01 Warner-Lambert Company LLC New cholesterolemia-lowering carboxyalkylether compound
US6861555B2 (en) * 2000-01-25 2005-03-01 Warner-Lambert Company Calcium dicarboxylate ethers, methods of making same, and treatment of vascular disease and diabetes therewith
ATE320803T1 (de) * 1998-01-28 2006-04-15 Warner Lambert Co Verfahren zur behandlung von alzheimerschen krankheit
AU768474B2 (en) * 1998-09-30 2003-12-11 Warner-Lambert Company Method for preventing or delaying catheter-based revascularization
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DE60138686D1 (de) 2000-01-25 2009-06-25 Warner Lambert Co Calcium-dicarboxylatether, verfahren zu deren herstellung
US20040092574A1 (en) * 2000-02-07 2004-05-13 Bisgaier Charles Larry Statin-Lp(a) inhibitor combinations
EA005245B1 (ru) * 2000-04-26 2004-12-30 Уорнер-Ламберт Компани Комбинация карбоксиалкиловых эфиров и гипотензивных агентов и фармацевтическое применение
CA2414783A1 (en) * 2000-07-14 2002-01-24 Warner-Lambert Company Treatment of eating disorders using carboxyalkylethers
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Also Published As

Publication number Publication date
FI973713A0 (fi) 1997-09-17
NO307878B1 (no) 2000-06-13
NO974397D0 (no) 1997-09-23
CN1182415A (zh) 1998-05-20
US5750569A (en) 1998-05-12
CN1100747C (zh) 2003-02-05
US5783600A (en) 1998-07-21
HUP9801825A2 (hu) 1998-12-28
ES2148733T3 (es) 2000-10-16
UA46020C2 (uk) 2002-05-15
DE69608268D1 (de) 2000-06-15
FI973713A (fi) 1997-09-24
SK128697A3 (en) 1999-02-11
GR3034109T3 (en) 2000-11-30
JPH11502532A (ja) 1999-03-02
EE9700375A (et) 1998-06-15
DK0820428T3 (da) 2000-08-28
KR100408612B1 (ko) 2004-03-26
EP0820428B1 (en) 2000-05-10
BG63534B1 (bg) 2002-04-30
AU692359B2 (en) 1998-06-04
US5648387A (en) 1997-07-15
CA2215233C (en) 2006-07-11
PL181673B1 (pl) 2001-08-31
EP0820428A1 (en) 1998-01-28
KR19980703233A (ko) 1998-10-15
CA2215233A1 (en) 1996-10-03
RU2191772C2 (ru) 2002-10-27
SK282897B6 (sk) 2003-01-09
PL322407A1 (en) 1998-01-19
HK1009438A1 (en) 1999-09-10
DE69608268T2 (de) 2000-11-09
ATE192732T1 (de) 2000-05-15
CZ289556B6 (cs) 2002-02-13
CZ292297A3 (cs) 1998-10-14
WO1996030328A1 (en) 1996-10-03
MX9707198A (es) 1997-11-29
ZA962275B (en) 1996-11-27
AU4776896A (en) 1996-10-16
NO974397L (no) 1997-11-20
PT820428E (pt) 2000-09-29
BG101993A (en) 1998-05-29
NZ302170A (en) 1999-04-29
HUP9801825A3 (en) 2001-01-29
US5756544A (en) 1998-05-26
JP3885115B2 (ja) 2007-02-21

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