ATE192732T1 - Caroboxy- oder tetrazolengruppen enthaltende dialkylether - Google Patents
Caroboxy- oder tetrazolengruppen enthaltende dialkyletherInfo
- Publication number
- ATE192732T1 ATE192732T1 AT96903794T AT96903794T ATE192732T1 AT E192732 T1 ATE192732 T1 AT E192732T1 AT 96903794 T AT96903794 T AT 96903794T AT 96903794 T AT96903794 T AT 96903794T AT E192732 T1 ATE192732 T1 AT E192732T1
- Authority
- AT
- Austria
- Prior art keywords
- tetrazolene
- caroboxy
- dialkylethers
- groups
- noninsulin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/235—Saturated compounds containing more than one carboxyl group
- C07C59/305—Saturated compounds containing more than one carboxyl group containing ether groups, groups, groups, or groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
- C07C47/277—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/28—Saturated compounds having —CHO groups bound to carbon atoms of rings other than six—membered aromatic rings
- C07C47/37—Saturated compounds having —CHO groups bound to carbon atoms of rings other than six—membered aromatic rings containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/235—Saturated compounds containing more than one carboxyl group
- C07C59/305—Saturated compounds containing more than one carboxyl group containing ether groups, groups, groups, or groups
- C07C59/315—Saturated compounds containing more than one carboxyl group containing ether groups, groups, groups, or groups containing halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/235—Saturated compounds containing more than one carboxyl group
- C07C59/347—Saturated compounds containing more than one carboxyl group containing keto groups
- C07C59/353—Saturated compounds containing more than one carboxyl group containing keto groups containing rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
- C07C69/708—Ethers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Adhesives Or Adhesive Processes (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pigments, Carbon Blacks, Or Wood Stains (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Detergent Compositions (AREA)
- Medicinal Preparation (AREA)
- Absorbent Articles And Supports Therefor (AREA)
- Dental Preparations (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/409,780 US5648387A (en) | 1995-03-24 | 1995-03-24 | Carboxyalkylethers, formulations, and treatment of vascular diseases |
PCT/US1996/001639 WO1996030328A1 (en) | 1995-03-24 | 1996-02-05 | Terminal carboxy or tetrazole groups containing dialkyl ethers |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE192732T1 true ATE192732T1 (de) | 2000-05-15 |
Family
ID=23621941
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT96903794T ATE192732T1 (de) | 1995-03-24 | 1996-02-05 | Caroboxy- oder tetrazolengruppen enthaltende dialkylether |
Country Status (27)
Country | Link |
---|---|
US (4) | US5648387A (de) |
EP (1) | EP0820428B1 (de) |
JP (1) | JP3885115B2 (de) |
KR (1) | KR100408612B1 (de) |
CN (1) | CN1100747C (de) |
AT (1) | ATE192732T1 (de) |
AU (1) | AU692359B2 (de) |
BG (1) | BG63534B1 (de) |
CA (1) | CA2215233C (de) |
CZ (1) | CZ289556B6 (de) |
DE (1) | DE69608268T2 (de) |
DK (1) | DK0820428T3 (de) |
EE (1) | EE03520B1 (de) |
ES (1) | ES2148733T3 (de) |
FI (1) | FI973713A (de) |
GR (1) | GR3034109T3 (de) |
HK (1) | HK1009438A1 (de) |
HU (1) | HUP9801825A3 (de) |
NO (1) | NO307878B1 (de) |
NZ (1) | NZ302170A (de) |
PL (1) | PL181673B1 (de) |
PT (1) | PT820428E (de) |
RU (1) | RU2191772C2 (de) |
SK (1) | SK282897B6 (de) |
UA (1) | UA46020C2 (de) |
WO (1) | WO1996030328A1 (de) |
ZA (1) | ZA962275B (de) |
Families Citing this family (79)
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IL119971A (en) * | 1997-01-07 | 2003-02-12 | Yissum Res Dev Co | Pharmaceutical compositions containing dicarboxylic acids and derivatives thereof and some novel dicarboxylic acids |
SI1045691T1 (en) * | 1997-12-12 | 2005-04-30 | Warner-Lambert Company Llc | Statin-carboxyalkylether combinations |
WO2001055078A1 (en) | 2000-01-25 | 2001-08-02 | Warner-Lambert Company | Calcium dicarboxylate ethers, methods of making same, and treatment of vascular disease and diabetes therewith |
NZ503982A (en) * | 1997-12-12 | 2002-03-28 | Warner Lambert Co | Statin-carboxyalkylether combinations useful for treating vascular disorders and diabetes mellitus |
US20030105154A1 (en) * | 2001-10-24 | 2003-06-05 | Bisgaier Charles Larry | Statin-carboxyalkylether combinations |
US6861555B2 (en) * | 2000-01-25 | 2005-03-01 | Warner-Lambert Company | Calcium dicarboxylate ethers, methods of making same, and treatment of vascular disease and diabetes therewith |
WO1999030706A1 (en) * | 1997-12-12 | 1999-06-24 | Warner-Lambert Company | ANTIHYPERLIPIDEMIC STATIN-LP(a) INHIBITOR COMBINATIONS |
DE69833971T2 (de) * | 1998-01-28 | 2006-11-02 | Warner-Lambert Co. Llc | Verfahren zur behandlung der alzheimerschen krankheit |
EA007427B1 (ru) * | 1998-09-30 | 2006-10-27 | Варнер Ламберт Компани | Способ предотвращения или отсрочки катетерной реваскуляризации |
IL145712A0 (en) * | 1999-04-01 | 2002-07-25 | Esperion Therapeutics Inc | Ether compounds, compositions, and uses thereof |
EP1862444A3 (de) * | 1999-04-01 | 2008-01-09 | Esperion Therapeutics, Inc. | Etherverbindungen, Zusammensetzungen und Verwendungen dafür |
US20040092574A1 (en) * | 2000-02-07 | 2004-05-13 | Bisgaier Charles Larry | Statin-Lp(a) inhibitor combinations |
DE60107559T2 (de) * | 2000-04-26 | 2005-04-14 | Warner-Lambert Co. | Kombination von carboxyalkylethern mit antihypertensiva und pharmazeutische verwendung |
IL153788A0 (en) * | 2000-07-14 | 2003-07-31 | Warner Lambert Co | Treatment of eating disorders using carboxyalkylethers |
EP1326822A2 (de) | 2000-10-11 | 2003-07-16 | Esperion Therapeutics Inc. | Ketoverbindungen und zusammensetzungen zur behandlung von cholesterol und deren verwendung |
US20040122091A1 (en) * | 2000-10-11 | 2004-06-24 | Esperion Therapeutics, Inc. | Sulfoxide and bis-sulfoxide compounds and compositions for cholesterol management and related uses |
WO2002030884A2 (en) | 2000-10-11 | 2002-04-18 | Esperion Therapeutics, Inc. | Sulfide and disulfide compounds and compositions for cholesterol management and related uses |
BR0114623A (pt) | 2000-10-11 | 2005-12-13 | Esperion Therapeutics Inc | Composto, composição farmacêutica, métodos para tratar ou prevenir uma doença cardiovascular, uma dislipidemia, uma dislipoproteinemia, um distúrbio do metabolismo da glicose, trombótico e associado com o receptor ativado do proliferador de peroxissoma, a doença de alzheimer, a sìndrome x ou sìndrome metabólica, a septicemia, a obesidade, pancreatite, a hipertensão, doença renal, câncer, a inflamação e a impotência, em um paciente e para reduzir o teor de gordura da carne em animal de criação e de colesterol de ovos de aves domésticas |
US7304093B2 (en) * | 2000-10-11 | 2007-12-04 | Esperion Therapeutics, Inc. | Ketone compounds and compositions for cholesterol management and related uses |
CA2425121A1 (en) | 2000-10-11 | 2002-04-18 | Esperion Therapeutics, Inc. | Ether compounds and compositions for cholesterol management and related uses |
US20030225123A1 (en) * | 2001-03-22 | 2003-12-04 | Auerbach Bruce Jeffrey | Antihypertensive agents and use |
US20040072903A1 (en) * | 2001-05-08 | 2004-04-15 | Auerbach Bruce Jeffrey | Carboxyalkylether-acat inhibitors combinations |
US20050020694A1 (en) * | 2001-10-11 | 2005-01-27 | Dasseux Jean-Louis Henri | Sulfide and disulfide compounds and compositions for cholesterol management and related uses |
US20040204502A1 (en) * | 2001-10-11 | 2004-10-14 | Dasseux Jean-Louis Henri | Sulfoxide and bis-sulfoxide compounds and compositions for cholesterol management and related uses |
US20040192771A1 (en) * | 2001-10-11 | 2004-09-30 | Dasseux Jean-Louis Henri | Ether compounds and compositions for cholesterol management and related uses |
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EP3241833A1 (de) | 2010-10-18 | 2017-11-08 | Cerenis Therapeutics Holding SA | Verbindungen, zusammensetzungen und verfahren zur cholesterinmobilisierung |
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1995
- 1995-03-24 US US08/409,780 patent/US5648387A/en not_active Expired - Lifetime
-
1996
- 1996-02-05 CZ CZ19972922A patent/CZ289556B6/cs not_active IP Right Cessation
- 1996-02-05 DE DE69608268T patent/DE69608268T2/de not_active Expired - Lifetime
- 1996-02-05 PT PT96903794T patent/PT820428E/pt unknown
- 1996-02-05 EP EP96903794A patent/EP0820428B1/de not_active Expired - Lifetime
- 1996-02-05 PL PL96322407A patent/PL181673B1/pl not_active IP Right Cessation
- 1996-02-05 CN CN96193500A patent/CN1100747C/zh not_active Expired - Fee Related
- 1996-02-05 SK SK1286-97A patent/SK282897B6/sk unknown
- 1996-02-05 WO PCT/US1996/001639 patent/WO1996030328A1/en active IP Right Grant
- 1996-02-05 NZ NZ302170A patent/NZ302170A/en unknown
- 1996-02-05 ES ES96903794T patent/ES2148733T3/es not_active Expired - Lifetime
- 1996-02-05 CA CA002215233A patent/CA2215233C/en not_active Expired - Fee Related
- 1996-02-05 RU RU97118420/04A patent/RU2191772C2/ru not_active IP Right Cessation
- 1996-02-05 HU HU9801825A patent/HUP9801825A3/hu unknown
- 1996-02-05 AT AT96903794T patent/ATE192732T1/de not_active IP Right Cessation
- 1996-02-05 UA UA97105209A patent/UA46020C2/uk unknown
- 1996-02-05 KR KR1019970706637A patent/KR100408612B1/ko not_active IP Right Cessation
- 1996-02-05 JP JP52934296A patent/JP3885115B2/ja not_active Expired - Lifetime
- 1996-02-05 AU AU47768/96A patent/AU692359B2/en not_active Ceased
- 1996-02-05 DK DK96903794T patent/DK0820428T3/da active
- 1996-02-05 EE EE9700375A patent/EE03520B1/xx not_active IP Right Cessation
- 1996-03-20 ZA ZA962275A patent/ZA962275B/xx unknown
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1997
- 1997-02-25 US US08/806,582 patent/US5756544A/en not_active Expired - Lifetime
- 1997-02-25 US US08/806,580 patent/US5783600A/en not_active Expired - Lifetime
- 1997-02-25 US US08/805,533 patent/US5750569A/en not_active Expired - Lifetime
- 1997-09-17 FI FI973713A patent/FI973713A/fi not_active IP Right Cessation
- 1997-09-23 NO NO974397A patent/NO307878B1/no not_active IP Right Cessation
- 1997-10-24 BG BG101993A patent/BG63534B1/bg unknown
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1998
- 1998-09-04 HK HK98110440A patent/HK1009438A1/xx not_active IP Right Cessation
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2000
- 2000-08-02 GR GR20000401806T patent/GR3034109T3/el not_active IP Right Cessation
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