ECSP066978A - Compuestos amino y su uso como farmacéuticos - Google Patents
Compuestos amino y su uso como farmacéuticosInfo
- Publication number
- ECSP066978A ECSP066978A ECSP066978A ECSP066978A EC SP066978 A ECSP066978 A EC SP066978A EC SP066978 A ECSP066978 A EC SP066978A EC SP066978 A ECSP066978 A EC SP066978A
- Authority
- EC
- Ecuador
- Prior art keywords
- pharmaceuticals
- amino compounds
- diseases associated
- dehydrogenase type
- steroid dehydrogenase
- Prior art date
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- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/06—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/438—The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
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- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
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- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
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Abstract
La presente invención se relaciona a los inhibidores del 11-b hidroxil esteroide deshidrogenasa tipo 1, antagonistas del receptor de mineralocorticoides (MR) y las composiciones farmacéuticas de los mismos. Los compuestos de la invención pueden ser útiles en el tratamiento de varias enfermedades asociadas con la expresión o actividad del 11-b hidroxil esteroide deshidrogenasa tipo 1 y/o enfermedades asociadas con el exceso de aldosterona
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
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US56927304P | 2004-05-07 | 2004-05-07 | |
US60205104P | 2004-08-17 | 2004-08-17 | |
US60279104P | 2004-08-19 | 2004-08-19 | |
US63880304P | 2004-12-22 | 2004-12-22 |
Publications (1)
Publication Number | Publication Date |
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ECSP066978A true ECSP066978A (es) | 2006-12-29 |
Family
ID=35394113
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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ECSP066978 ECSP066978A (es) | 2004-05-07 | 2006-11-08 | Compuestos amino y su uso como farmacéuticos |
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US (7) | US7304081B2 (es) |
EP (2) | EP2963021A1 (es) |
JP (2) | JP5265913B2 (es) |
KR (1) | KR101252227B1 (es) |
AU (1) | AU2005243222C1 (es) |
BR (1) | BRPI0510736B1 (es) |
CA (1) | CA2565238C (es) |
CR (1) | CR8702A (es) |
CY (1) | CY1116779T1 (es) |
DK (1) | DK1756063T3 (es) |
EA (1) | EA025359B1 (es) |
EC (1) | ECSP066978A (es) |
ES (1) | ES2550006T3 (es) |
GE (1) | GEP201706611B (es) |
HK (2) | HK1101397A1 (es) |
HR (1) | HRP20151064T1 (es) |
HU (1) | HUE025521T2 (es) |
IL (1) | IL179042A (es) |
ME (1) | ME02231B (es) |
MX (1) | MX340538B (es) |
NO (1) | NO340031B1 (es) |
NZ (1) | NZ550775A (es) |
PL (1) | PL1756063T3 (es) |
PT (1) | PT1756063E (es) |
RS (1) | RS54236B1 (es) |
SG (1) | SG151329A1 (es) |
SI (1) | SI1756063T1 (es) |
TW (1) | TWI350168B (es) |
WO (1) | WO2005110992A1 (es) |
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