ATE421519T1 - Substituierte bizyklische thiophen-derivate, diese verbindungen enthaltende zusammensetzungen und anwendungsverfahren - Google Patents
Substituierte bizyklische thiophen-derivate, diese verbindungen enthaltende zusammensetzungen und anwendungsverfahrenInfo
- Publication number
- ATE421519T1 ATE421519T1 AT03752080T AT03752080T ATE421519T1 AT E421519 T1 ATE421519 T1 AT E421519T1 AT 03752080 T AT03752080 T AT 03752080T AT 03752080 T AT03752080 T AT 03752080T AT E421519 T1 ATE421519 T1 AT E421519T1
- Authority
- AT
- Austria
- Prior art keywords
- compounds
- methods
- compositions containing
- bizyclic
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Fertilizers (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41014502P | 2002-09-12 | 2002-09-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE421519T1 true ATE421519T1 (de) | 2009-02-15 |
Family
ID=31994072
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03752080T ATE421519T1 (de) | 2002-09-12 | 2003-09-08 | Substituierte bizyklische thiophen-derivate, diese verbindungen enthaltende zusammensetzungen und anwendungsverfahren |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7273876B2 (de) |
| EP (1) | EP1549655B1 (de) |
| JP (1) | JP2006503034A (de) |
| AT (1) | ATE421519T1 (de) |
| AU (1) | AU2003270390A1 (de) |
| CA (1) | CA2498106A1 (de) |
| DE (1) | DE60325985D1 (de) |
| WO (1) | WO2004024065A2 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7138529B2 (en) | 2003-04-16 | 2006-11-21 | Hoffmann-La Roche Inc. | Substituted 3-cyanothiophene acetamides as glucagon receptor antagonists |
| US20050085531A1 (en) * | 2003-10-03 | 2005-04-21 | Hodge Carl N. | Thiophene-based compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions, and uses thereof |
| TWI350168B (en) | 2004-05-07 | 2011-10-11 | Incyte Corp | Amido compounds and their use as pharmaceuticals |
| ATE400319T1 (de) | 2004-05-28 | 2008-07-15 | Nycomed Gmbh | Tetrahydropyridothiophene |
| ATE397000T1 (de) | 2004-06-04 | 2008-06-15 | Nycomed Gmbh | Tetrahydropyridothiophenen zur verwendung in der behandlung von krebs |
| AU2005251485A1 (en) | 2004-06-11 | 2005-12-22 | 4Sc Ag | Tetrahydropyridothiophenes for treating hyperproliferative disorders |
| JP2008529989A (ja) | 2005-02-09 | 2008-08-07 | ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング | 癌のような増殖性の疾病の治療用のテトラヒドロピリドチオフェン |
| US7741488B2 (en) | 2005-02-11 | 2010-06-22 | 4Sc Ag | Tetrahydropyridothiophenes as antiproliferative agents for the treatment of cancer |
| AU2006251167A1 (en) * | 2005-05-25 | 2006-11-30 | 4Sc Ag | Tetrahydropyridothiophenes for use in the treatment of cancer |
| EP1893618A2 (de) * | 2005-05-25 | 2008-03-05 | Nycomed GmbH | Tetrahydropyridothiophene zur verwendung bei der behandlung von krebs |
| MX2008009178A (es) | 2006-01-19 | 2008-12-05 | Athersys Inc | Tiofenil y pirrolil acepinas como ligandos del receptor de serotonina 5-ht2c y sus usos. |
| SG11201504749TA (en) | 2012-12-21 | 2015-07-30 | Abt Holding Co | Benzazepines as serotonin 5-ht2c receptor ligands and uses thereof |
| US9309262B2 (en) | 2013-03-13 | 2016-04-12 | Abt Holding Company | Thienylindole azepines as serotonin 5-HT2C receptor ligands and uses thereof |
| WO2020200154A1 (zh) * | 2019-03-30 | 2020-10-08 | 上海凌达生物医药有限公司 | 一类噻吩并氮杂环类化合物、制备方法和用途 |
| CN111909167B (zh) * | 2019-05-07 | 2021-11-19 | 华东师范大学 | 一种哌啶并噻吩衍生物及其在制备治疗银屑病的药物中的应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DD272078A1 (de) * | 1986-04-15 | 1989-09-27 | Dresden Arzneimittel | Verfahren zur herstellung von 6-substituierten 2-acylamio-4,5,6,7-tetrahydro-thieno[2,3-c]-pyridin-3-carbonsaeure-derivaten |
| WO2000014090A1 (en) * | 1998-09-02 | 2000-03-16 | Novo Nordisk A/S | 4,5,6,7-tetrahydro-thieno[2,3-c]pyridine derivatives |
| US7138529B2 (en) * | 2003-04-16 | 2006-11-21 | Hoffmann-La Roche Inc. | Substituted 3-cyanothiophene acetamides as glucagon receptor antagonists |
-
2003
- 2003-09-08 WO PCT/US2003/028033 patent/WO2004024065A2/en active Application Filing
- 2003-09-08 US US10/527,762 patent/US7273876B2/en not_active Expired - Fee Related
- 2003-09-08 CA CA002498106A patent/CA2498106A1/en not_active Abandoned
- 2003-09-08 EP EP03752080A patent/EP1549655B1/de not_active Expired - Lifetime
- 2003-09-08 DE DE60325985T patent/DE60325985D1/de not_active Expired - Fee Related
- 2003-09-08 AU AU2003270390A patent/AU2003270390A1/en not_active Abandoned
- 2003-09-08 AT AT03752080T patent/ATE421519T1/de not_active IP Right Cessation
- 2003-09-08 JP JP2004536137A patent/JP2006503034A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP1549655A2 (de) | 2005-07-06 |
| JP2006503034A (ja) | 2006-01-26 |
| AU2003270390A1 (en) | 2004-04-30 |
| DE60325985D1 (de) | 2009-03-12 |
| WO2004024065A3 (en) | 2004-05-13 |
| CA2498106A1 (en) | 2004-03-25 |
| US20050239865A1 (en) | 2005-10-27 |
| EP1549655A4 (de) | 2006-05-31 |
| WO2004024065A2 (en) | 2004-03-25 |
| US7273876B2 (en) | 2007-09-25 |
| EP1549655B1 (de) | 2009-01-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |