ATE397000T1 - Tetrahydropyridothiophenen zur verwendung in der behandlung von krebs - Google Patents

Tetrahydropyridothiophenen zur verwendung in der behandlung von krebs

Info

Publication number
ATE397000T1
ATE397000T1 AT05750033T AT05750033T ATE397000T1 AT E397000 T1 ATE397000 T1 AT E397000T1 AT 05750033 T AT05750033 T AT 05750033T AT 05750033 T AT05750033 T AT 05750033T AT E397000 T1 ATE397000 T1 AT E397000T1
Authority
AT
Austria
Prior art keywords
tetrahydropyridothiophenes
cancer
treatment
compounds
proliferative
Prior art date
Application number
AT05750033T
Other languages
English (en)
Inventor
Klaus Pekari
Thomas Baer
Mathias Schmidt
Thomas Beckers
Bjoern Bartels
Petra Gimmnich
Original Assignee
Nycomed Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Gmbh filed Critical Nycomed Gmbh
Application granted granted Critical
Publication of ATE397000T1 publication Critical patent/ATE397000T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT05750033T 2004-06-04 2005-06-03 Tetrahydropyridothiophenen zur verwendung in der behandlung von krebs ATE397000T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP04102531 2004-06-04

Publications (1)

Publication Number Publication Date
ATE397000T1 true ATE397000T1 (de) 2008-06-15

Family

ID=34929170

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05750033T ATE397000T1 (de) 2004-06-04 2005-06-03 Tetrahydropyridothiophenen zur verwendung in der behandlung von krebs

Country Status (9)

Country Link
US (2) US7517986B2 (de)
EP (1) EP1756118B1 (de)
JP (1) JP2008501668A (de)
AT (1) ATE397000T1 (de)
AU (1) AU2005250184B2 (de)
CA (1) CA2568718A1 (de)
DE (1) DE602005007220D1 (de)
ES (1) ES2308504T3 (de)
WO (1) WO2005118592A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2818547B1 (fr) * 2000-12-22 2006-11-17 Oreal Nouveaux derives c-glycosides et utilisation
SI1753512T1 (sl) 2004-05-28 2008-12-31 4Sc Ag Tetrahidropiridotiofeni
WO2005118592A1 (en) * 2004-06-04 2005-12-15 Altana Pharma Ag Tetrahydropyridothiophenes for use in the treatment of cancer
AU2005251485A1 (en) 2004-06-11 2005-12-22 4Sc Ag Tetrahydropyridothiophenes for treating hyperproliferative disorders
WO2006084869A1 (en) * 2005-02-09 2006-08-17 Nycomed Gmbh Tetrahydropyridothiophenes for the treatment of proliferative diseases such as cancer
AU2006251167A1 (en) * 2005-05-25 2006-11-30 4Sc Ag Tetrahydropyridothiophenes for use in the treatment of cancer
CA2609004A1 (en) * 2005-05-25 2006-11-30 Nycomed Gmbh Tetrahydropyridothiophenes for use in the treatment of cancer
CA2660794A1 (en) * 2006-08-16 2008-02-21 4Sc Ag Ntetrahydropyridothiophene derivatives for the treatment of cancer
CN102188698B (zh) * 2010-03-08 2014-10-01 上海南方模式生物科技发展有限公司 核糖核酸酶和青蒿素的联用
KR101633453B1 (ko) * 2015-06-17 2016-06-24 한국과학기술연구원 대사성 글루타메이트 수용체 1, 5에 활성을 보이는 신규 테트라하이드로티에노[2,3-ｃ]피리딘 유도체
CN108558848A (zh) * 2018-04-19 2018-09-21 华东师范大学 一种环烷烃并噻吩衍生物及其制备方法和医药用途

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DE1225167B (de) * 1965-04-07 1966-09-22 Huels Chemische Werke Ag Verfahren zur Herstellung aliphatischer, aromatischer oder gemischt aliphatisch-aromatischer Sulfone
JPS5498337A (en) * 1978-01-06 1979-08-03 Dai Ichi Seiyaku Co Ltd Anticarcinogenic and/or antimetastatic agent
DD272078A1 (de) 1986-04-15 1989-09-27 Dresden Arzneimittel Verfahren zur herstellung von 6-substituierten 2-acylamio-4,5,6,7-tetrahydro-thieno[2,3-c]-pyridin-3-carbonsaeure-derivaten
DE4039734A1 (de) 1990-12-13 1992-06-17 Basf Ag Substituierte 2-aminothiophene enthaltende herbizide mittel
JP3074640B2 (ja) * 1995-12-22 2000-08-07 インターナショナル・ビジネス・マシーンズ・コーポレ−ション 液晶表示装置の駆動方法
GB9614718D0 (en) 1996-07-12 1996-09-04 Bayer Ag 3-ureido-pyridofurans and -pyridothiophenes
CN1300291A (zh) * 1998-03-12 2001-06-20 诺沃挪第克公司 蛋白质酪氨酸磷酸酶(ptp酶)的调节物
WO1999046267A1 (en) 1998-03-12 1999-09-16 Novo Nordisk A/S Modulators of protein tyrosine phosphatases (ptpases)
WO2002092076A1 (en) * 2001-05-16 2002-11-21 Cytovia, Inc. Substituted coumarins and quinolines as caspases activators
US20040171603A1 (en) * 2001-05-18 2004-09-02 Janos Pato Novel therapeutic targets for the treatment of mycobacterial infections and compounds useful therefor
US20030232994A1 (en) * 2001-10-04 2003-12-18 Shao-Po Lu Bicyclic thiophene derivatives and combinatorial libraries thereof
JP4103425B2 (ja) * 2002-03-28 2008-06-18 セイコーエプソン株式会社 電気光学装置、電子機器及び投射型表示装置
WO2004024066A2 (en) * 2002-09-12 2004-03-25 Merck & Co., Inc. Method of treating diabetes and related conditions
WO2004024065A2 (en) 2002-09-12 2004-03-25 Merck & Co., Inc. Substituted bicyclic thiophene derivatives, compostions containing such compounds and methods of use
IL154306A0 (en) 2003-02-05 2003-09-17 Rimonyx Pharmaceuticals Ltd Pharmaceutical compositions comprising thieno [2,3-c] pyridine derivatives and use thereof
US7138529B2 (en) * 2003-04-16 2006-11-21 Hoffmann-La Roche Inc. Substituted 3-cyanothiophene acetamides as glucagon receptor antagonists
US20050085531A1 (en) 2003-10-03 2005-04-21 Hodge Carl N. Thiophene-based compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions, and uses thereof
GB0324653D0 (en) 2003-10-22 2003-11-26 Syngenta Participations Ag Fungicides
JP2007515429A (ja) 2003-12-19 2007-06-14 エリクシアー ファーマシューティカルズ， インコーポレイテッド 障害を治療する方法
US7745630B2 (en) * 2003-12-22 2010-06-29 Justin Stephen Bryans Triazolyl piperidine arginine vasopressin receptor modulators
SI1753512T1 (sl) 2004-05-28 2008-12-31 4Sc Ag Tetrahidropiridotiofeni
WO2005118592A1 (en) * 2004-06-04 2005-12-15 Altana Pharma Ag Tetrahydropyridothiophenes for use in the treatment of cancer
AU2005251485A1 (en) 2004-06-11 2005-12-22 4Sc Ag Tetrahydropyridothiophenes for treating hyperproliferative disorders

Also Published As

Publication number Publication date
US7517986B2 (en) 2009-04-14
WO2005118592A1 (en) 2005-12-15
AU2005250184B2 (en) 2011-04-21
EP1756118B1 (de) 2008-05-28
US20090163538A1 (en) 2009-06-25
US20070213360A1 (en) 2007-09-13
CA2568718A1 (en) 2005-12-15
WO2005118592A8 (en) 2006-10-12
ES2308504T3 (es) 2008-12-01
JP2008501668A (ja) 2008-01-24
EP1756118A1 (de) 2007-02-28
AU2005250184A1 (en) 2005-12-15
DE602005007220D1 (de) 2008-07-10

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