ATE486878T1 - Benzothienopyridine zur verwendung als inhibitoren von eg5-kinesin - Google Patents
Benzothienopyridine zur verwendung als inhibitoren von eg5-kinesinInfo
- Publication number
- ATE486878T1 ATE486878T1 AT05777861T AT05777861T ATE486878T1 AT E486878 T1 ATE486878 T1 AT E486878T1 AT 05777861 T AT05777861 T AT 05777861T AT 05777861 T AT05777861 T AT 05777861T AT E486878 T1 ATE486878 T1 AT E486878T1
- Authority
- AT
- Austria
- Prior art keywords
- benzothienopyridines
- kinesin inhibitors
- compounds
- kinesin
- inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Oncology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- AIDS & HIV (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP04103958 | 2004-08-18 | ||
EP04104175 | 2004-08-31 | ||
PCT/EP2005/054054 WO2006018435A1 (en) | 2004-08-18 | 2005-08-17 | Benzothienopyridines for use as inhibitors of eg5 kinesin |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE486878T1 true ATE486878T1 (de) | 2010-11-15 |
Family
ID=35285513
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT05777861T ATE486878T1 (de) | 2004-08-18 | 2005-08-17 | Benzothienopyridine zur verwendung als inhibitoren von eg5-kinesin |
Country Status (8)
Country | Link |
---|---|
US (2) | US7718665B2 (de) |
EP (1) | EP1781667B1 (de) |
JP (1) | JP2008509971A (de) |
AT (1) | ATE486878T1 (de) |
AU (1) | AU2005273867B2 (de) |
CA (1) | CA2576619A1 (de) |
DE (1) | DE602005024572D1 (de) |
WO (1) | WO2006018435A1 (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2005273867B2 (en) | 2004-08-18 | 2010-12-23 | 4Sc Ag | Benzothienopyridines for use as inhibitors of Eg5 kinesin |
AU2006208709A1 (en) * | 2005-01-27 | 2006-08-03 | 4Sc Ag | Novel indolopyridines , benzofuranopyridines and benzothienopyridines |
WO2006079644A1 (en) * | 2005-01-28 | 2006-08-03 | Nycomed Gmbh | Indolopyridines, benzofuranopyridines and benzothienopyridines |
US20090246169A1 (en) * | 2006-02-22 | 2009-10-01 | Matthias Vennemann | Indolopyridines as eg5 kinesin modulators |
WO2007096393A1 (en) * | 2006-02-22 | 2007-08-30 | 4Sc Ag | Indolopyridines as eg5 kinesin modulators |
CA2658223A1 (en) * | 2006-07-13 | 2008-01-17 | 4Sc Ag | Benzopyranopyrazoles |
CA2697246A1 (en) * | 2007-08-22 | 2009-02-26 | 4Sc Ag | Indolopyridines as inhibitors of the kinesin spindle protein (eg5) |
EP2033962A1 (de) * | 2007-08-22 | 2009-03-11 | 4Sc Ag | Tetrazyclische Indolopyridinderivate als EG5-Hemmer |
US20130210733A1 (en) | 2010-06-17 | 2013-08-15 | Cytokinetics, Inc. | Methods of treating lung disease |
KR101390616B1 (ko) | 2012-03-28 | 2014-04-29 | 주식회사 두산 | 신규 화합물 및 이를 포함하는 유기 전계 발광 소자 |
CN110464722B (zh) * | 2019-06-06 | 2023-05-23 | 暨南大学 | 一类小分子化合物或其药学上可接受的盐在制备抗肿瘤转移药物中的应用 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0357122A3 (de) * | 1988-08-29 | 1991-10-23 | Duphar International Research B.V | Verwendung von Beta-Carbolinen und deren bio-isosterischen Benzofuran- und Benzothiophenanalogen zur Herstellung eines Arzneimittels mit cytostatischer Wirkung |
GB9514473D0 (en) | 1995-07-14 | 1995-09-13 | Glaxo Lab Sa | Chemical compounds |
US6217104B1 (en) * | 1999-06-16 | 2001-04-17 | Cts Fahrzeug Dachsysteme Gmbh | Retractable hard top module |
US6890933B1 (en) * | 2000-02-24 | 2005-05-10 | President And Fellows Of Harvard College | Kinesin inhibitors |
ES2267831T3 (es) | 2000-10-03 | 2007-03-16 | Lilly Icos Llc | Derivados de piridoindol condensado. |
US7067315B2 (en) * | 2001-05-22 | 2006-06-27 | President And Fellows Of Harvard College | Identification of anti-protozoal agents |
CA2460939C (en) | 2001-09-19 | 2008-07-29 | Pharmacia Corporation | Substituted pyrazolyl compounds for the treatment of inflammation |
AU2003247891A1 (en) | 2002-07-08 | 2004-01-23 | Merck & Co., Inc. | Mitotic kinesin binding site |
US7022850B2 (en) | 2003-05-22 | 2006-04-04 | Bristol-Myers Squibb Co. | Bicyclicpyrimidones and their use to treat diseases |
JP4580932B2 (ja) | 2003-06-12 | 2010-11-17 | メルク・シャープ・エンド・ドーム・コーポレイション | 有糸分裂キネシン阻害剤のプロドラッグ |
AU2005273867B2 (en) | 2004-08-18 | 2010-12-23 | 4Sc Ag | Benzothienopyridines for use as inhibitors of Eg5 kinesin |
AU2006212863A1 (en) | 2005-02-10 | 2006-08-17 | Merck Sharp & Dohme Corp. | Mitotic kinesin inhibitors |
US20090246169A1 (en) | 2006-02-22 | 2009-10-01 | Matthias Vennemann | Indolopyridines as eg5 kinesin modulators |
WO2007096393A1 (en) | 2006-02-22 | 2007-08-30 | 4Sc Ag | Indolopyridines as eg5 kinesin modulators |
EP2035426A1 (de) | 2006-06-14 | 2009-03-18 | 4Sc Ag | Pyrazolopyrimidone |
CA2658223A1 (en) | 2006-07-13 | 2008-01-17 | 4Sc Ag | Benzopyranopyrazoles |
-
2005
- 2005-08-17 AU AU2005273867A patent/AU2005273867B2/en not_active Ceased
- 2005-08-17 DE DE602005024572T patent/DE602005024572D1/de active Active
- 2005-08-17 US US11/659,738 patent/US7718665B2/en not_active Expired - Fee Related
- 2005-08-17 WO PCT/EP2005/054054 patent/WO2006018435A1/en active Application Filing
- 2005-08-17 CA CA002576619A patent/CA2576619A1/en not_active Abandoned
- 2005-08-17 EP EP05777861A patent/EP1781667B1/de active Active
- 2005-08-17 JP JP2007526460A patent/JP2008509971A/ja active Pending
- 2005-08-17 AT AT05777861T patent/ATE486878T1/de not_active IP Right Cessation
-
2010
- 2010-03-30 US US12/749,623 patent/US8044065B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU2005273867B2 (en) | 2010-12-23 |
US7718665B2 (en) | 2010-05-18 |
JP2008509971A (ja) | 2008-04-03 |
DE602005024572D1 (de) | 2010-12-16 |
WO2006018435A1 (en) | 2006-02-23 |
US20100183550A1 (en) | 2010-07-22 |
EP1781667A1 (de) | 2007-05-09 |
CA2576619A1 (en) | 2006-02-23 |
US20070232596A1 (en) | 2007-10-04 |
EP1781667B1 (de) | 2010-11-03 |
AU2005273867A1 (en) | 2006-02-23 |
US8044065B2 (en) | 2011-10-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |