ATE478076T1 - Azaxanthonen zur behandlung von tumoren - Google Patents

Azaxanthonen zur behandlung von tumoren

Info

Publication number
ATE478076T1
ATE478076T1 AT06851384T AT06851384T ATE478076T1 AT E478076 T1 ATE478076 T1 AT E478076T1 AT 06851384 T AT06851384 T AT 06851384T AT 06851384 T AT06851384 T AT 06851384T AT E478076 T1 ATE478076 T1 AT E478076T1
Authority
AT
Austria
Prior art keywords
tumors
azaxanthones
treatment
mesenchymel
retarding
Prior art date
Application number
AT06851384T
Other languages
English (en)
Inventor
Grzegorz Pietrzynski
Valery Alakhov
Alexandre Semov
Original Assignee
Supratek Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Supratek Pharma Inc filed Critical Supratek Pharma Inc
Application granted granted Critical
Publication of ATE478076T1 publication Critical patent/ATE478076T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4741—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having oxygen as a ring hetero atom, e.g. tubocuraran derivatives, noscapine, bicuculline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT06851384T 2005-12-13 2006-12-12 Azaxanthonen zur behandlung von tumoren ATE478076T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/301,930 US7772255B2 (en) 2005-12-13 2005-12-13 Method of treating tumors with azaxanthones
PCT/IB2006/004291 WO2008020269A2 (en) 2005-12-13 2006-12-12 A method of treating tumors with azaxanthones

Publications (1)

Publication Number Publication Date
ATE478076T1 true ATE478076T1 (de) 2010-09-15

Family

ID=38140264

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06851384T ATE478076T1 (de) 2005-12-13 2006-12-12 Azaxanthonen zur behandlung von tumoren

Country Status (7)

Country Link
US (2) US7772255B2 (de)
EP (1) EP1968981B1 (de)
JP (1) JP2009519318A (de)
AT (1) ATE478076T1 (de)
CA (1) CA2633112A1 (de)
DE (1) DE602006016333D1 (de)
WO (1) WO2008020269A2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010089707A1 (en) * 2009-02-04 2010-08-12 Yeda Research And Development Co. Ltd. Methods and kits for determining sensitivity or resistance of prostate cancer to radiation therapy
CN101899051B (zh) * 2010-05-17 2013-03-20 中国人民解放军第二军医大学 1-氮杂呫吨酮-3-甲酰胺类化合物及制备方法和抗肿瘤用途
WO2012016930A1 (en) 2010-08-05 2012-02-09 Universite De Droit Et Sante De Lille Compound useful for the treatment of nonsense-mutation-mediated diseases and pharmaceutical composition comprising said compound
ES2659763T3 (es) * 2011-02-14 2018-03-19 The Regents Of The University Of Michigan Composiciones y procedimientos para el tratamiento de obesidad y trastornos relacionados
US9365581B2 (en) 2013-05-02 2016-06-14 The Regents Of The University Of Michigan Deuterated amlexanox
WO2017112954A1 (en) 2015-12-23 2017-06-29 Moonshot Pharma Llc Methods for inducing an immune response by promoting premature termination codon read-through
EP3407974A4 (de) * 2016-01-29 2019-08-28 The Regents Of The University Of Michigan Amlexanox-analoga
EP3641752A4 (de) * 2017-06-22 2021-03-17 Moonshot Pharma LLC Verfahren zur behandlung von krebs mit zusammensetzungen mit amlexanox und immunmodulatoren
CN109718374B (zh) * 2017-10-27 2022-03-08 中国科学院分子细胞科学卓越创新中心 Irf3抑制剂在制备yap过度激活的癌症的治疗或预防药物中的用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU513456B2 (en) 1977-03-08 1980-12-04 Takeda Chemical Industries Ltd. l-Azaxanthone-3-carboxylic acids
JPS53111096A (en) * 1977-03-08 1978-09-28 Takeda Chem Ind Ltd 1-azaxanthone-3-carboxylic acid derivative and its preparation
US4539326A (en) * 1982-08-20 1985-09-03 Takeda Chemical Industries, Ltd. 5-Oxo-5H-(1)benzopyrano(2,3-b)pyridine derivatives, their production and use as anti-inflammatory agents
JP2963496B2 (ja) * 1989-06-26 1999-10-18 第一製薬株式会社 ベンゾピラノピリジン誘導体
US6552055B2 (en) * 1996-12-11 2003-04-22 Dana-Farber Cancer Institute Methods and pharmaceutical compositions for inhibiting tumor cell growth
AU2001269516B2 (en) * 2000-07-13 2006-09-14 Takeda Pharmaceutical Company Limited Lipid-rich plaque regressing agents
US20020103219A1 (en) * 2000-10-05 2002-08-01 Jeremy Jacob Stable viscous liquid formulations of amlexanox for the prevention and treatment of mucosal diseases and disorders
DE10250081A1 (de) * 2002-10-25 2004-05-13 Boehringer Ingelheim Vetmedica Gmbh Wasserlösliche Meloxicam Granulate
JP2006511551A (ja) * 2002-12-12 2006-04-06 ファルマシア・コーポレーション マイトジェン活性化プロテインキナーゼ活性化プロテインキナーゼ−２の三環系アミノシアノピリジン阻害剤

Also Published As

Publication number Publication date
EP1968981A4 (de) 2009-04-15
DE602006016333D1 (de) 2010-09-30
HK1116186A1 (en) 2008-12-19
US20090042923A1 (en) 2009-02-12
WO2008020269A3 (en) 2008-07-24
EP1968981B1 (de) 2010-08-18
WO2008020269A2 (en) 2008-02-21
EP1968981A2 (de) 2008-09-17
US7772255B2 (en) 2010-08-10
JP2009519318A (ja) 2009-05-14
US20070135473A1 (en) 2007-06-14
CA2633112A1 (en) 2008-02-21

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Legal Events

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