ATE400319T1 - Tetrahydropyridothiophene - Google Patents

Tetrahydropyridothiophene

Info

Publication number
ATE400319T1
ATE400319T1 AT05749649T AT05749649T ATE400319T1 AT E400319 T1 ATE400319 T1 AT E400319T1 AT 05749649 T AT05749649 T AT 05749649T AT 05749649 T AT05749649 T AT 05749649T AT E400319 T1 ATE400319 T1 AT E400319T1
Authority
AT
Austria
Prior art keywords
tetrahydropyridothiophenes
compounds
proliferative
description
meanings indicated
Prior art date
Application number
AT05749649T
Other languages
English (en)
Inventor
Klaus Pekari
Thomas Baer
Bjoern Bartels
Mathias Schmidt
Thomas Beckers
Original Assignee
Nycomed Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Gmbh filed Critical Nycomed Gmbh
Application granted granted Critical
Publication of ATE400319T1 publication Critical patent/ATE400319T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
AT05749649T 2004-05-28 2005-05-25 Tetrahydropyridothiophene ATE400319T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04102413 2004-05-28
EP04104193 2004-09-01

Publications (1)

Publication Number Publication Date
ATE400319T1 true ATE400319T1 (de) 2008-07-15

Family

ID=35045196

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05749649T ATE400319T1 (de) 2004-05-28 2005-05-25 Tetrahydropyridothiophene

Country Status (25)

Country Link
US (2) US7723523B2 (de)
EP (1) EP1753512B1 (de)
JP (1) JP4881297B2 (de)
KR (1) KR20070037578A (de)
CN (1) CN1988934B (de)
AT (1) ATE400319T1 (de)
AU (1) AU2005249718B2 (de)
BR (1) BRPI0511461A (de)
CA (1) CA2567648A1 (de)
CY (1) CY1108399T1 (de)
DE (1) DE602005008050D1 (de)
DK (1) DK1753512T3 (de)
EA (1) EA012280B1 (de)
ES (1) ES2309765T3 (de)
HK (1) HK1106171A1 (de)
HR (1) HRP20080499T3 (de)
IL (1) IL178727A (de)
MX (1) MXPA06013383A (de)
NO (1) NO20065907L (de)
NZ (1) NZ550513A (de)
PL (1) PL1753512T3 (de)
PT (1) PT1753512E (de)
RS (1) RS50613B (de)
SI (1) SI1753512T1 (de)
WO (1) WO2005118071A2 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4881297B2 (ja) 2004-05-28 2012-02-22 フォーエスシー アクチエンゲゼルシャフト 新規のテトラヒドロピリドチオフェン
JP2008501668A (ja) 2004-06-04 2008-01-24 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 癌の治療に使用するためのテトラヒドロピリドチオフェン
JP2008501768A (ja) 2004-06-11 2008-01-24 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規の化合物及びテトラヒドロピリドチオフェンの使用
WO2006084869A1 (en) 2005-02-09 2006-08-17 Nycomed Gmbh Tetrahydropyridothiophenes for the treatment of proliferative diseases such as cancer
JP2008542242A (ja) 2005-05-25 2008-11-27 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規のテトラヒドロピリドチオフェン
CA2609004A1 (en) 2005-05-25 2006-11-30 Nycomed Gmbh Tetrahydropyridothiophenes for use in the treatment of cancer
AU2007285714A1 (en) * 2006-08-16 2008-02-21 4Sc Ag Ntetrahydropyridothiophene derivatives for the treatment of cancer
CA2660604A1 (en) * 2006-08-16 2008-02-21 4Sc Ag Tetrahydrobenzothiophene derivatives
TWI492759B (zh) * 2008-03-05 2015-07-21 Otsuka Pharma Co Ltd 膽甾烷醇衍生物之併用用途
TW201005466A (en) * 2008-07-24 2010-02-01 Advanced Analog Technology Inc Low dropout regulator
CA2739740A1 (en) * 2008-10-24 2010-04-29 Gruenenthal Gmbh Substituted 4,5,6,7-tetrahydrothienopyridines as kcnq2/3 modulators for treating pain, epilepsy and urinary incontinence
ES2534800T3 (es) * 2009-03-04 2015-04-29 Otsuka Pharmaceutical Co., Ltd. Derivado de colestanol para uso combinado
CN104478850A (zh) * 2014-12-08 2015-04-01 上海应用技术学院 一种2-氨基噻吩-3甲酰胺的衍生物的制备方法

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE272078C (de)
DE1225167B (de) * 1965-04-07 1966-09-22 Huels Chemische Werke Ag Verfahren zur Herstellung aliphatischer, aromatischer oder gemischt aliphatisch-aromatischer Sulfone
JPS5498337A (en) * 1978-01-06 1979-08-03 Dai Ichi Seiyaku Co Ltd Anticarcinogenic and/or antimetastatic agent
DD272078A1 (de) 1986-04-15 1989-09-27 Dresden Arzneimittel Verfahren zur herstellung von 6-substituierten 2-acylamio-4,5,6,7-tetrahydro-thieno[2,3-c]-pyridin-3-carbonsaeure-derivaten
DE4039734A1 (de) 1990-12-13 1992-06-17 Basf Ag Substituierte 2-aminothiophene enthaltende herbizide mittel
GB9310700D0 (en) 1993-05-24 1993-07-07 Zeneca Ltd Novel composition
JP3074640B2 (ja) * 1995-12-22 2000-08-07 インターナショナル・ビジネス・マシーンズ・コーポレ−ション 液晶表示装置の駆動方法
GB9614718D0 (en) 1996-07-12 1996-09-04 Bayer Ag 3-ureido-pyridofurans and -pyridothiophenes
WO1999046267A1 (en) 1998-03-12 1999-09-16 Novo Nordisk A/S Modulators of protein tyrosine phosphatases (ptpases)
ATE308546T1 (de) * 1998-03-12 2005-11-15 Novo Nordisk As Modulatoren der protein tyrosin phosphatase (ptpases)
AU5154699A (en) 1998-09-02 2000-03-27 Novo Nordisk A/S 4,5,6,7-tetrahydro-thieno(2,3-c)pyridine derivatives
GB0114185D0 (en) 2001-06-12 2001-08-01 Protherics Molecular Design Lt Compounds
WO2002092076A1 (en) 2001-05-16 2002-11-21 Cytovia, Inc. Substituted coumarins and quinolines as caspases activators
US20040171603A1 (en) * 2001-05-18 2004-09-02 Janos Pato Novel therapeutic targets for the treatment of mycobacterial infections and compounds useful therefor
US20030232994A1 (en) * 2001-10-04 2003-12-18 Shao-Po Lu Bicyclic thiophene derivatives and combinatorial libraries thereof
MXPA04009283A (es) 2002-03-27 2005-01-25 Altana Pharma Ag Nuevos derivados de alcoxipiridina.
JP4103425B2 (ja) * 2002-03-28 2008-06-18 セイコーエプソン株式会社 電気光学装置、電子機器及び投射型表示装置
US20090018149A1 (en) 2002-04-09 2009-01-15 Andrea Missio 4,5,6,7-tetrahydrobenzo[b]thiophene derivatives and methods for medical intervention against mycobacterial infections
US7012100B1 (en) 2002-06-04 2006-03-14 Avolix Pharmaceuticals, Inc. Cell migration inhibiting compositions and methods and compositions for treating cancer
DE60325985D1 (de) 2002-09-12 2009-03-12 Merck & Co Inc Substituierte bizyklische thiophen-derivate, diese verbindungen enthaltende zusammensetzungen und anwendungsverfahren
WO2004024066A2 (en) 2002-09-12 2004-03-25 Merck & Co., Inc. Method of treating diabetes and related conditions
TW200503994A (en) 2003-01-24 2005-02-01 Novartis Ag Organic compounds
IL154306A0 (en) 2003-02-05 2003-09-17 Rimonyx Pharmaceuticals Ltd Pharmaceutical compositions comprising thieno [2,3-c] pyridine derivatives and use thereof
US7138529B2 (en) 2003-04-16 2006-11-21 Hoffmann-La Roche Inc. Substituted 3-cyanothiophene acetamides as glucagon receptor antagonists
CA2572750A1 (en) 2003-09-10 2005-03-17 Anil Koul Heterobicyclic compounds as pharmaceutically active agents
US7279488B2 (en) 2003-10-01 2007-10-09 Nycomed Gmbh Imidazopyridine-derivatives as inducible no-synthase inhibitors
US20050085531A1 (en) 2003-10-03 2005-04-21 Hodge Carl N. Thiophene-based compounds exhibiting ATP-utilizing enzyme inhibitory activity, and compositions, and uses thereof
GB0324653D0 (en) 2003-10-22 2003-11-26 Syngenta Participations Ag Fungicides
MXPA06007054A (es) 2003-12-19 2007-04-17 Elixir Pharmaceuticals Inc Metodos para tratar una enfermedad.
US7745630B2 (en) * 2003-12-22 2010-06-29 Justin Stephen Bryans Triazolyl piperidine arginine vasopressin receptor modulators
JP4881297B2 (ja) 2004-05-28 2012-02-22 フォーエスシー アクチエンゲゼルシャフト 新規のテトラヒドロピリドチオフェン
JP2008501668A (ja) 2004-06-04 2008-01-24 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 癌の治療に使用するためのテトラヒドロピリドチオフェン
JP2008501768A (ja) 2004-06-11 2008-01-24 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規の化合物及びテトラヒドロピリドチオフェンの使用
SE0401970D0 (sv) 2004-08-02 2004-08-02 Astrazeneca Ab Novel compounds
WO2006084869A1 (en) 2005-02-09 2006-08-17 Nycomed Gmbh Tetrahydropyridothiophenes for the treatment of proliferative diseases such as cancer
US7741488B2 (en) 2005-02-11 2010-06-22 4Sc Ag Tetrahydropyridothiophenes as antiproliferative agents for the treatment of cancer
CA2609004A1 (en) 2005-05-25 2006-11-30 Nycomed Gmbh Tetrahydropyridothiophenes for use in the treatment of cancer
JP2008542242A (ja) 2005-05-25 2008-11-27 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 新規のテトラヒドロピリドチオフェン
CA2660604A1 (en) 2006-08-16 2008-02-21 4Sc Ag Tetrahydrobenzothiophene derivatives

Also Published As

Publication number Publication date
SI1753512T1 (sl) 2008-12-31
IL178727A0 (en) 2007-02-11
PT1753512E (pt) 2008-10-14
AU2005249718B2 (en) 2011-01-27
PL1753512T3 (pl) 2009-03-31
EP1753512B1 (de) 2008-07-09
MXPA06013383A (es) 2007-01-23
DE602005008050D1 (de) 2008-08-21
JP4881297B2 (ja) 2012-02-22
DK1753512T3 (da) 2008-11-17
AU2005249718A1 (en) 2005-12-15
EP1753512A2 (de) 2007-02-21
EA200602157A1 (ru) 2007-06-29
WO2005118071A3 (en) 2006-06-01
CN1988934B (zh) 2011-01-05
HK1106171A1 (en) 2008-03-07
IL178727A (en) 2010-12-30
US7803945B2 (en) 2010-09-28
US7723523B2 (en) 2010-05-25
CA2567648A1 (en) 2005-12-15
US20070244112A1 (en) 2007-10-18
ES2309765T3 (es) 2008-12-16
EA012280B1 (ru) 2009-08-28
BRPI0511461A (pt) 2007-12-26
NO20065907L (no) 2006-12-19
KR20070037578A (ko) 2007-04-05
JP2008500993A (ja) 2008-01-17
RS50613B (sr) 2010-06-30
US20090270378A1 (en) 2009-10-29
NZ550513A (en) 2009-10-30
CN1988934A (zh) 2007-06-27
CY1108399T1 (el) 2014-02-12
HRP20080499T3 (en) 2008-11-30
WO2005118071A2 (en) 2005-12-15

Similar Documents

Publication Publication Date Title
ATE400319T1 (de) Tetrahydropyridothiophene
NL301145I2 (nl) Tirbanibulin
CY1122522T1 (el) Μετα αρσενικωδες νατριο για χρηση στην αγωγη του πολλαπλου μυελωματος
ATE517896T1 (de) P38-kinase-inhibitoren
UA96592C2 (uk) Індолопіридини як модулятори кінезину eg5
DE602005002413D1 (de) Wegwerfhöschen
EA200900781A1 (ru) 4-фенилпиран-3,5-дионы, 4-фенилтиопиран-3,5-дионы и циклогексантрионы, как новые гербициды
ATE461217T1 (de) Glp-1-verbindungen
WO2005118592A8 (en) Tetrahydropyridothiophenes for use in the treatment of cancer
EA200700717A1 (ru) Сульфонамиды
DK1585737T3 (da) Uraciler med herbicid virkning
WO2009074677A3 (en) Pyrazolotriazines
ATE486878T1 (de) Benzothienopyridine zur verwendung als inhibitoren von eg5-kinesin
WO2006125813A3 (en) Tetrahydropyridothiophenes for use in the treatment of cancer
WO2006125815A3 (en) Tetrahydropyridothiophenes for use in the treatment of cancer
WO2008006883A3 (en) Benzopyranopyrazoles
UY28344A1 (es) Nuevos compuestos
FR2858695B1 (fr) Calculateur personnel.
NL1026117A1 (nl) Rolstoel.
UY34598A (es) Antranilamidas insecticidas
ES1056890Y (es) Mesa de oficina.
ES1051664Y (es) Mesa desmontable.
ES1057650Y (es) Camison hospitalario.
ES1057560Y (es) Mesa-atril abatible y desmontable.
UA5977U (en) 5-phenylpropenelydene-rodanin-3-propionate sodium possesses antihypoxic activity

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1753512

Country of ref document: EP

EEIH Change in the person of patent owner