EA201690868A1 - Персонализированная иммунотерапия нескольких видов нейрональных опухолей и опухолей головного мозга - Google Patents

Персонализированная иммунотерапия нескольких видов нейрональных опухолей и опухолей головного мозга

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Publication number
EA201690868A1
EA201690868A1 EA201690868A EA201690868A EA201690868A1 EA 201690868 A1 EA201690868 A1 EA 201690868A1 EA 201690868 A EA201690868 A EA 201690868A EA 201690868 A EA201690868 A EA 201690868A EA 201690868 A1 EA201690868 A1 EA 201690868A1
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EA
Eurasian Patent Office
Prior art keywords
tumors
relates
present
brain
several types
Prior art date
Application number
EA201690868A
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English (en)
Other versions
EA036517B1 (ru
Inventor
Тони Вайншенк
Йенс Фритше
Штеффен Вальтер
Норберт Хильф
Оливер Шор
Харпреет Сингх
Сабрина Куттруфф-Кокви
Колетт Сонг
Original Assignee
Имматикс Байотекнолоджиз Гмбх
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Application filed by Имматикс Байотекнолоджиз Гмбх filed Critical Имматикс Байотекнолоджиз Гмбх
Publication of EA201690868A1 publication Critical patent/EA201690868A1/ru
Publication of EA036517B1 publication Critical patent/EA036517B1/ru

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Abstract

Изобретение относится к пептидам, нуклеиновым кислотам и клеткам для применения в иммунотерапевтических методах. В частности, настоящее изобретение относится к иммунотерапии рака. Настоящее изобретение относится далее к опухолеассоциированным цитотоксическим пептидным эпитопам Т-клеток (ЦТЛ), в отдельности или в комбинации с другими опухолеассоциированными пептидами, которые служат в качестве активных фармацевтических ингредиентов вакцинных композиций, стимулирующих противоопухолевые иммунные ответы. Настоящее изобретение относится к пептидным последовательностям и их вариантам, образованным из молекул HLA I и II классов человеческих опухолевых клеток, которые могут быть использованы в вакцинных композициях для вызывания противоопухолевых иммунных ответов.
EA201690868A 2013-11-04 2014-11-03 Пептид, который связывается с молекулой главного комплекса гистосовместимости человека i класса; антитело; нуклеиновая кислота; вектор экспрессии; активированный цитотоксический t-лимфоцит; клетка-хозяин и фармацевтическая композиция для лечения рака EA036517B1 (ru)

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US201361899680P 2013-11-04 2013-11-04
GBGB1319446.9A GB201319446D0 (en) 2013-11-04 2013-11-04 Personalized immunotherapy against several neuronal and brain tumors
PCT/EP2014/073588 WO2015063302A2 (en) 2013-11-04 2014-11-03 Personalized immunotherapy against several neuronal and brain tumors

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