EA201692103A1 - Новый метод иммунотерапии нескольких видов опухолевых заболеваний крови, таких как острый миелоидный лейкоз (омл) - Google Patents

Новый метод иммунотерапии нескольких видов опухолевых заболеваний крови, таких как острый миелоидный лейкоз (омл)

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EA201692103A1
EA201692103A1 EA201692103A EA201692103A EA201692103A1 EA 201692103 A1 EA201692103 A1 EA 201692103A1 EA 201692103 A EA201692103 A EA 201692103A EA 201692103 A EA201692103 A EA 201692103A EA 201692103 A1 EA201692103 A1 EA 201692103A1
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Eurasian Patent Office
Prior art keywords
present
relates
immunotherapy
aml
blood
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EA201692103A
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English (en)
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EA035456B1 (ru
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Джулиан Стикель
Дэниел Ковалевски
Клаудиа Берлин
Ханс-Георг Раммензее
Стефан Стеванович
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Имматикс Байотекнолоджиз Гмбх
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Publication of EA201692103A1 publication Critical patent/EA201692103A1/ru
Publication of EA035456B1 publication Critical patent/EA035456B1/ru

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Abstract

Настоящее изобретение относится к пептидам, нуклеиновым кислотам и клеткам для применения в иммунотерапевтических методах. В частности, настоящее изобретение относится к иммунотерапии рака. Настоящее изобретение относится далее к опухолеассоциированным цитотоксическим пептидным эпитопам Т-клеток (ЦТЛ), в отдельности или в комбинации с другими опухолеассоциированными пептидами, которые служат в качестве активных фармацевтических ингредиентов вакцинных композиций, стимулирующих противоопухолевые иммунные ответы. Настоящее изобретение относится к нескольким новым пептидным последовательностям и их вариантам, образованным из молекул HLA класса I и HLA класса II человеческих опухолевых клеток, которые могут быть использованы в вакцинных композициях для вызывания противоопухолевых иммунных ответов.
EA201692103A 2014-05-09 2015-05-08 Новый метод иммунотерапии нескольких видов опухолевых заболеваний крови, таких как острый миелоидный лейкоз (омл) EA035456B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461990980P 2014-05-09 2014-05-09
GBGB1408255.6A GB201408255D0 (en) 2014-05-09 2014-05-09 Novel immunotherapy against several tumours of the blood, such as acute myeloid leukemia (AML)
PCT/EP2015/060168 WO2015169945A2 (en) 2014-05-09 2015-05-08 Novel immunotherapy against several tumors of the blood, such as acute myeloid leukemia (aml)

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EA201692103A1 true EA201692103A1 (ru) 2017-04-28
EA035456B1 EA035456B1 (ru) 2020-06-18

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EA202090751A EA202090751A3 (ru) 2014-05-09 2015-05-08 Новый метод иммунотерапии нескольких видов опухолевых заболеваний крови, таких как острый миелоидный лейкоз (омл)
EA201692103A EA035456B1 (ru) 2014-05-09 2015-05-08 Новый метод иммунотерапии нескольких видов опухолевых заболеваний крови, таких как острый миелоидный лейкоз (омл)

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US (2) US10064924B2 (ru)
EP (3) EP3449937A1 (ru)
JP (1) JP6659582B2 (ru)
KR (1) KR20170003976A (ru)
CN (1) CN106459167A (ru)
AU (2) AU2015257652B2 (ru)
BR (1) BR112016025035A2 (ru)
CA (1) CA2946349A1 (ru)
CR (1) CR20160531A (ru)
DK (1) DK3140319T3 (ru)
EA (2) EA202090751A3 (ru)
ES (1) ES2747734T3 (ru)
GB (1) GB201408255D0 (ru)
HU (1) HUE045177T2 (ru)
LT (1) LT3140319T (ru)
MA (3) MA49280A (ru)
ME (1) ME03565B (ru)
MX (1) MX2016014711A (ru)
PL (1) PL3140319T3 (ru)
PT (1) PT3140319T (ru)
RS (1) RS59471B1 (ru)
SG (1) SG11201608332SA (ru)
SI (1) SI3140319T1 (ru)
TW (2) TW201920246A (ru)
WO (1) WO2015169945A2 (ru)

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