EA201300535A1 - Водный раствор амброксола - Google Patents

Водный раствор амброксола

Info

Publication number
EA201300535A1
EA201300535A1 EA201300535A EA201300535A EA201300535A1 EA 201300535 A1 EA201300535 A1 EA 201300535A1 EA 201300535 A EA201300535 A EA 201300535A EA 201300535 A EA201300535 A EA 201300535A EA 201300535 A1 EA201300535 A1 EA 201300535A1
Authority
EA
Eurasian Patent Office
Prior art keywords
ambroxol
water solution
content
aqueous solution
total
Prior art date
Application number
EA201300535A
Other languages
English (en)
Inventor
Джианлуиджи Пассетти
Original Assignee
Лектио Фармаэнтвиклунгс - Унд Фервертунгс Гмбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45094329&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA201300535(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Лектио Фармаэнтвиклунгс - Унд Фервертунгс Гмбх filed Critical Лектио Фармаэнтвиклунгс - Унд Фервертунгс Гмбх
Publication of EA201300535A1 publication Critical patent/EA201300535A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pain & Pain Management (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Chemical And Physical Treatments For Wood And The Like (AREA)

Abstract

Настоящее изобретение касается водного раствора, включающего кислотно-аддитивную соль амброксола, где содержание амброксола составляет от 0,1 до 7% (вес./об.), общее содержание полиспиртов, выбранных из полиолов и полиалкиленгликолей, составляет по крайней мере 20% (вес./об.), общее содержание спиртов составляет ниже 1% (вес./об.) и указанный водный раствор не содержит бензойной кислоты и/или ее солей с органическими или неорганическими основаниями.
EA201300535A 2010-12-23 2011-12-22 Водный раствор амброксола EA201300535A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10196711 2010-12-23
US201061428269P 2010-12-30 2010-12-30
PCT/EP2011/073754 WO2012085185A1 (en) 2010-12-23 2011-12-22 Aqueous solution of ambroxol

Publications (1)

Publication Number Publication Date
EA201300535A1 true EA201300535A1 (ru) 2013-08-30

Family

ID=45094329

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201300535A EA201300535A1 (ru) 2010-12-23 2011-12-22 Водный раствор амброксола

Country Status (13)

Country Link
EP (1) EP2654719A1 (ru)
JP (1) JP2014503542A (ru)
KR (1) KR20130140042A (ru)
CN (1) CN103269685A (ru)
AR (1) AR084537A1 (ru)
AU (1) AU2011347257A1 (ru)
BR (1) BR112013012815A2 (ru)
CA (1) CA2817453A1 (ru)
CL (1) CL2013001297A1 (ru)
EA (1) EA201300535A1 (ru)
MX (1) MX2013005500A (ru)
NZ (1) NZ609742A (ru)
WO (1) WO2012085185A1 (ru)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102083621B1 (ko) * 2013-06-13 2020-03-02 한미약품 주식회사 암브록솔 및 레보드로프로피진을 포함하는 안정성이 개선된 경구용 액상 제제
CN103462942B (zh) * 2013-08-20 2016-12-28 湖南赛隆药业有限公司 一种吸入用盐酸氨溴索溶液
CN104316482A (zh) * 2014-08-15 2015-01-28 河北菲尼斯生物技术有限公司 一种盐酸氨溴索颗粒的质量控制方法
CN105287367B (zh) * 2015-10-13 2018-07-10 华润三九（南昌）药业有限公司 一种盐酸氨溴索的口服液体制剂及其制备方法与应用
CN109060473B (zh) * 2018-07-27 2021-03-05 商洛学院 一种盐酸氨溴索杂质对照品的制备方法
CN113995721A (zh) * 2020-07-27 2022-02-01 德国吉麦医疗技术有限公司 一种盐酸氨溴索口腔喷雾溶液及其制备方法
CN112168783A (zh) * 2020-10-26 2021-01-05 山东裕欣药业有限公司 一种呼吸系统药物口服喷雾剂及制备方法
CN112168782A (zh) * 2020-10-26 2021-01-05 山东裕欣药业有限公司 一种呼吸系统药物口服喷雾剂的制备方法
CN114129510A (zh) * 2021-12-03 2022-03-04 聊城大学 一种复方磺胺注射剂及制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU574360B2 (en) * 1983-05-13 1988-07-07 Reichert, D. Antisnoring agent
JP2000007561A (ja) * 1998-06-18 2000-01-11 Nissho Corp 塩酸アンブロキソール水溶液製剤
DE19933148A1 (de) 1999-07-20 2001-01-25 Boehringer Ingelheim Int Ambroxolhaltige Lutschtablette
US7138133B2 (en) 2001-10-10 2006-11-21 The Procter & Gamble Company Orally administered liquid compositions
US20030171391A1 (en) 2002-01-25 2003-09-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Ambroxol for the treatment of chronic pain
DE10240802A1 (de) 2002-08-30 2004-04-15 W.L. Gore & Associates Gmbh IR reflektierendes Material
DE10332486A1 (de) 2003-07-16 2005-02-10 Boehringer Ingelheim Pharma Gmbh & Co. Kg Ambroxol für die Behandlung akuter Schmerzen
EP1672989B1 (en) * 2003-09-09 2012-04-25 3M Innovative Properties Company Concentrated antimicrobial compositions and methods
US20050075403A1 (en) 2003-10-02 2005-04-07 Boehringer Ingelheim Pharma Gmbh & Co. Kg Ambroxol for the treatment of inflammation in the pharynx
ITMI20032463A1 (it) 2003-12-16 2005-06-17 Advance Holdings Ltd Soluzione acquosa concentrata a base di ambroxolo
DE102004021992A1 (de) 2004-05-03 2005-11-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg Topische Zubereitung enthaltend Ambroxol
CN101961307B (zh) * 2010-09-14 2012-07-25 武汉人福药业有限责任公司 治疗呼吸道疾病的口服液及其制备方法

Also Published As

Publication number Publication date
KR20130140042A (ko) 2013-12-23
BR112013012815A2 (pt) 2016-09-13
AR084537A1 (es) 2013-05-22
MX2013005500A (es) 2013-09-26
EP2654719A1 (en) 2013-10-30
CN103269685A (zh) 2013-08-28
JP2014503542A (ja) 2014-02-13
WO2012085185A1 (en) 2012-06-28
CL2013001297A1 (es) 2013-10-11
CA2817453A1 (en) 2012-06-28
AU2011347257A1 (en) 2013-05-23
NZ609742A (en) 2015-01-30

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