NZ609742A - Aqueous solution of ambroxol - Google Patents

Aqueous solution of ambroxol

Info

Publication number
NZ609742A
NZ609742A NZ609742A NZ60974211A NZ609742A NZ 609742 A NZ609742 A NZ 609742A NZ 609742 A NZ609742 A NZ 609742A NZ 60974211 A NZ60974211 A NZ 60974211A NZ 609742 A NZ609742 A NZ 609742A
Authority
NZ
New Zealand
Prior art keywords
ambroxol
aqueous solution
total content
content
polyalkyleneglycols
Prior art date
Application number
NZ609742A
Inventor
Gianluigi Passetti
Original Assignee
Lectio Pharmaentwicklungs Und Verwertungs Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45094329&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NZ609742(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lectio Pharmaentwicklungs Und Verwertungs Gmbh filed Critical Lectio Pharmaentwicklungs Und Verwertungs Gmbh
Publication of NZ609742A publication Critical patent/NZ609742A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Abstract

609742 Disclosed herein is an aqueous solution comprising an acid addition salt of ambroxol, wherein the ambroxol content is ranging from 0.1% to 7% (w/v), the total content of polyalcohols selected from polyols and polyalkyleneglycols is at least 20% (w/v), the total content of alcohols is lower than 1% (w/v), and said aqueous solution is free of benzoic acid and/or salts thereof with organic or inorganic bases.
NZ609742A 2010-12-23 2011-12-22 Aqueous solution of ambroxol NZ609742A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10196711 2010-12-23
US201061428269P 2010-12-30 2010-12-30
PCT/EP2011/073754 WO2012085185A1 (en) 2010-12-23 2011-12-22 Aqueous solution of ambroxol

Publications (1)

Publication Number Publication Date
NZ609742A true NZ609742A (en) 2015-01-30

Family

ID=45094329

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ609742A NZ609742A (en) 2010-12-23 2011-12-22 Aqueous solution of ambroxol

Country Status (13)

Country Link
EP (1) EP2654719A1 (en)
JP (1) JP2014503542A (en)
KR (1) KR20130140042A (en)
CN (1) CN103269685A (en)
AR (1) AR084537A1 (en)
AU (1) AU2011347257A1 (en)
BR (1) BR112013012815A2 (en)
CA (1) CA2817453A1 (en)
CL (1) CL2013001297A1 (en)
EA (1) EA201300535A1 (en)
MX (1) MX2013005500A (en)
NZ (1) NZ609742A (en)
WO (1) WO2012085185A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102083621B1 (en) * 2013-06-13 2020-03-02 한미약품 주식회사 Oral liquid formulation having improved stability comprising ambroxol and levodropropizine
CN103462942B (en) * 2013-08-20 2016-12-28 湖南赛隆药业有限公司 A kind of suction ambroxol hydrochloride solution
CN104316482A (en) * 2014-08-15 2015-01-28 河北菲尼斯生物技术有限公司 A quality control method for ambroxol hydrochloride particles
CN105287367B (en) * 2015-10-13 2018-07-10 华润三九（南昌）药业有限公司 A kind of oral liquid of ambroxol hydrochloride and preparation method and application
CN109060473B (en) * 2018-07-27 2021-03-05 商洛学院 Preparation method of ambroxol hydrochloride impurity reference substance
CN113995721A (en) * 2020-07-27 2022-02-01 德国吉麦医疗技术有限公司 Ambroxol hydrochloride oral spray solution and preparation method thereof
CN112168783A (en) * 2020-10-26 2021-01-05 山东裕欣药业有限公司 Oral medicine spray for respiratory system and preparation method thereof
CN112168782A (en) * 2020-10-26 2021-01-05 山东裕欣药业有限公司 Preparation method of respiratory system medicine oral spray
CN114129510A (en) * 2021-12-03 2022-03-04 聊城大学 Compound sulfanilamide injection and preparation method thereof

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU574360B2 (en) * 1983-05-13 1988-07-07 Reichert, D. Antisnoring agent
JP2000007561A (en) * 1998-06-18 2000-01-11 Nissho Corp Ambroxol hydrochloride aqueous solution preparation
DE19933148A1 (en) 1999-07-20 2001-01-25 Boehringer Ingelheim Int Lozenge containing ambroxol
US7138133B2 (en) 2001-10-10 2006-11-21 The Procter & Gamble Company Orally administered liquid compositions
US20030171391A1 (en) 2002-01-25 2003-09-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Ambroxol for the treatment of chronic pain
DE10240802A1 (en) 2002-08-30 2004-04-15 W.L. Gore & Associates Gmbh IR reflective material
DE10332486A1 (en) 2003-07-16 2005-02-10 Boehringer Ingelheim Pharma Gmbh & Co. Kg Ambroxol for the treatment of acute pain
EP1672989B1 (en) * 2003-09-09 2012-04-25 3M Innovative Properties Company Concentrated antimicrobial compositions and methods
US20050075403A1 (en) 2003-10-02 2005-04-07 Boehringer Ingelheim Pharma Gmbh & Co. Kg Ambroxol for the treatment of inflammation in the pharynx
ITMI20032463A1 (en) 2003-12-16 2005-06-17 Advance Holdings Ltd AQUEOUS CONCENTRATED AMBROXOL SOLUTION
DE102004021992A1 (en) 2004-05-03 2005-11-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg Topical preparation containing ambroxol
CN101961307B (en) * 2010-09-14 2012-07-25 武汉人福药业有限责任公司 Oral liquid for treating respiratory disease and preparation method thereof

Also Published As

Publication number Publication date
AR084537A1 (en) 2013-05-22
CA2817453A1 (en) 2012-06-28
MX2013005500A (en) 2013-09-26
EP2654719A1 (en) 2013-10-30
BR112013012815A2 (en) 2016-09-13
CN103269685A (en) 2013-08-28
KR20130140042A (en) 2013-12-23
WO2012085185A1 (en) 2012-06-28
JP2014503542A (en) 2014-02-13
EA201300535A1 (en) 2013-08-30
AU2011347257A1 (en) 2013-05-23
CL2013001297A1 (en) 2013-10-11

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Legal Events

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LAPS Patent lapsed