EA200601562A1 - Сокристаллы госсипола и их применение - Google Patents

Сокристаллы госсипола и их применение

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Publication number
EA200601562A1
EA200601562A1 EA200601562A EA200601562A EA200601562A1 EA 200601562 A1 EA200601562 A1 EA 200601562A1 EA 200601562 A EA200601562 A EA 200601562A EA 200601562 A EA200601562 A EA 200601562A EA 200601562 A1 EA200601562 A1 EA 200601562A1
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Eurasian Patent Office
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sossicles
application
state
gossypol
relates
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EA200601562A
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English (en)
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EA011218B1 (ru
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Шаомэн Ван
Дажон Ян
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Дзе Риджентс Оф Дзе Юниверсити Оф Мичиган
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Publication of EA200601562A1 publication Critical patent/EA200601562A1/ru
Publication of EA011218B1 publication Critical patent/EA011218B1/ru

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  • Health & Medical Sciences (AREA)
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  • Veterinary Medicine (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
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  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Данное изобретение относится к композициям, содержащим сокристаллы (-)-госсипола с C-карбоновой кислотой или C-сульфоновой кислотой, которые применимы в качестве ингибиторов белков семейства Bcl-2. Изобретение также относится к применению сокристаллов (-)-госсипола с С-карбоновой кислотой или C-сульфоновой кислотой для индукции апоптоза в клетках и для сенсибилизации клеток к индукции апоптотической клеточной гибели.
EA200601562A 2004-03-25 2005-03-24 Сокристаллы госсипола и их применение EA011218B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55624904P 2004-03-25 2004-03-25
PCT/US2005/009673 WO2005094804A1 (en) 2004-03-25 2005-03-24 Gossypol co-crystals and the use thereof

Publications (2)

Publication Number Publication Date
EA200601562A1 true EA200601562A1 (ru) 2007-02-27
EA011218B1 EA011218B1 (ru) 2009-02-27

Family

ID=35063489

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200601562A EA011218B1 (ru) 2004-03-25 2005-03-24 Сокристаллы госсипола и их применение

Country Status (15)

Country Link
US (3) US7342046B2 (ru)
EP (1) EP1732529A4 (ru)
JP (1) JP2007530568A (ru)
KR (2) KR100906843B1 (ru)
CN (1) CN1960719B (ru)
AU (2) AU2005228998B2 (ru)
BR (1) BRPI0509182A (ru)
CA (1) CA2561303C (ru)
EA (1) EA011218B1 (ru)
IL (1) IL178286A0 (ru)
MX (1) MXPA06010938A (ru)
NO (1) NO20064829L (ru)
SG (1) SG151299A1 (ru)
WO (1) WO2005094804A1 (ru)
ZA (1) ZA200607956B (ru)

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KR101579371B1 (ko) * 2014-02-27 2015-12-22 국립암센터 고시폴 및 펜포르민을 유효성분으로 함유하는 암 치료용 약제학적 조성물
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ATE387911T1 (de) 2003-06-25 2008-03-15 Burnham Inst Katecholderivate zur behandlung von krebs
SG151299A1 (en) * 2004-03-25 2009-04-30 Univ Michigan Gossypol co-crystals and the use thereof

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EP1732529A4 (en) 2009-02-25
EA011218B1 (ru) 2009-02-27
US7342046B2 (en) 2008-03-11
KR20070026473A (ko) 2007-03-08
AU2009200387A1 (en) 2009-02-19
US20090082445A1 (en) 2009-03-26
CN1960719B (zh) 2011-12-07
CA2561303A1 (en) 2005-10-13
AU2005228998A1 (en) 2005-10-13
KR100906843B1 (ko) 2009-07-08
NO20064829L (no) 2006-12-20
SG151299A1 (en) 2009-04-30
CN1960719A (zh) 2007-05-09
ZA200607956B (en) 2008-02-27
EP1732529A1 (en) 2006-12-20
MXPA06010938A (es) 2007-01-25
US20070293585A1 (en) 2007-12-20
US20050234135A1 (en) 2005-10-20
CA2561303C (en) 2011-01-18
AU2005228998B2 (en) 2008-11-06
JP2007530568A (ja) 2007-11-01
US7432300B2 (en) 2008-10-07
BRPI0509182A (pt) 2007-09-18
IL178286A0 (en) 2007-03-08
WO2005094804A1 (en) 2005-10-13
KR20080097496A (ko) 2008-11-05

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