EA200600076A1 - Композиции и способы увеличения активности теломеразы - Google Patents

Композиции и способы увеличения активности теломеразы

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Publication number
EA200600076A1
EA200600076A1 EA200600076A EA200600076A EA200600076A1 EA 200600076 A1 EA200600076 A1 EA 200600076A1 EA 200600076 A EA200600076 A EA 200600076A EA 200600076 A EA200600076 A EA 200600076A EA 200600076 A1 EA200600076 A1 EA 200600076A1
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EA
Eurasian Patent Office
Prior art keywords
increasing
compositions
telomerase
activity
methods
Prior art date
Application number
EA200600076A
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English (en)
Other versions
EA009442B1 (ru
Inventor
Келвин Б. Харлей
Эллисон С. Чин
Тсутому Акама
Нэнси Юк-ю Ип
Юнг-ху Вонг
Дэвид М. Миллер-Мартини
Original Assignee
Герон Корпорейшн
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Publication date
Application filed by Герон Корпорейшн filed Critical Герон Корпорейшн
Publication of EA200600076A1 publication Critical patent/EA200600076A1/ru
Publication of EA009442B1 publication Critical patent/EA009442B1/ru

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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • C07—ORGANIC CHEMISTRY
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Abstract

Настоящее изобретение относится к способам и композициям для увеличения активности теломеразы в клетках. Такие композиции включают фармацевтические составы, включая наносимые местно составы и составы биологически активных добавок. Способы и композиции являются полезными для лечения заболеваний субъекта, таких как, например, ВИЧ инфекция, различные дегенеративные заболевания и острые или хронические кожные алименты, путем повышения активности теломеразы в клетках и тканях субъекта. Они также полезны для увеличения репликативной способности в клеточной культуре при ex vivo клеточной терапии и пролиферации стволовых клеток.
EA200600076A 2003-06-23 2004-06-23 Композиции и способы увеличения активности теломеразы EA009442B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48098803P 2003-06-23 2003-06-23
PCT/US2004/020277 WO2005000245A2 (en) 2003-06-23 2004-06-23 Compositions and methods for increasing telomerase activity

Publications (2)

Publication Number Publication Date
EA200600076A1 true EA200600076A1 (ru) 2006-08-25
EA009442B1 EA009442B1 (ru) 2007-12-28

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EA200600076A EA009442B1 (ru) 2003-06-23 2004-06-23 Композиции и способы увеличения активности теломеразы

Country Status (24)

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US (3) US7846904B2 (ru)
EP (2) EP1644009B1 (ru)
JP (4) JP5583882B2 (ru)
KR (3) KR101312389B1 (ru)
CN (1) CN1809364B (ru)
AP (1) AP2280A (ru)
AU (2) AU2004251753C1 (ru)
BR (1) BRPI0411856A (ru)
CA (1) CA2528483C (ru)
CY (2) CY1119951T1 (ru)
DK (2) DK1644009T3 (ru)
EA (1) EA009442B1 (ru)
ES (2) ES2716528T3 (ru)
HR (2) HRP20180330T1 (ru)
HU (2) HUE036559T2 (ru)
LT (2) LT1644009T (ru)
MX (1) MXPA05013844A (ru)
NZ (1) NZ544191A (ru)
PL (2) PL1644009T3 (ru)
PT (2) PT2548880T (ru)
SI (2) SI2548880T1 (ru)
TR (2) TR201802543T4 (ru)
WO (1) WO2005000245A2 (ru)
ZA (1) ZA200509846B (ru)

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