IL137101A0 - Extension of cellular lifespan, methods and reagents - Google Patents

Extension of cellular lifespan, methods and reagents

Info

Publication number
IL137101A0
IL137101A0 IL13710199A IL13710199A IL137101A0 IL 137101 A0 IL137101 A0 IL 137101A0 IL 13710199 A IL13710199 A IL 13710199A IL 13710199 A IL13710199 A IL 13710199A IL 137101 A0 IL137101 A0 IL 137101A0
Authority
IL
Israel
Prior art keywords
reagents
extension
methods
cellular lifespan
lifespan
Prior art date
Application number
IL13710199A
Original Assignee
Cold Spring Harbor Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cold Spring Harbor Lab filed Critical Cold Spring Harbor Lab
Publication of IL137101A0 publication Critical patent/IL137101A0/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/162Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45Transferases (2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Zoology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Virology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL13710199A 1998-01-12 1999-01-12 Extension of cellular lifespan, methods and reagents IL137101A0 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US7122098P 1998-01-12 1998-01-12
US7145598P 1998-01-13 1998-01-13
US6365798A 1998-04-21 1998-04-21
PCT/US1999/000682 WO1999035243A2 (en) 1998-01-12 1999-01-12 Extension of cellular lifespan, methods and reagents

Publications (1)

Publication Number Publication Date
IL137101A0 true IL137101A0 (en) 2001-06-14

Family

ID=27370514

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13710199A IL137101A0 (en) 1998-01-12 1999-01-12 Extension of cellular lifespan, methods and reagents

Country Status (6)

Country Link
EP (1) EP1045697A2 (en)
JP (1) JP2002500040A (en)
AU (1) AU759437B2 (en)
CA (1) CA2315265A1 (en)
IL (1) IL137101A0 (en)
WO (1) WO1999035243A2 (en)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6572845B2 (en) * 1998-10-16 2003-06-03 Burt D. Ensley Recombinant hair treatment compositions
AU2156600A (en) * 1998-11-25 2000-06-13 Cold Spring Harbor Laboratory Methods and reagents for increasing proliferative capacity and preventing replicative senescence
IL147990A0 (en) * 1999-08-05 2002-09-12 Mcl Llc Multipotent adult stem cells and methods for isolation
US8609412B2 (en) 1999-08-05 2013-12-17 Regents Of The University Of Minnesota Mapc generation of lung tissue
US7015037B1 (en) 1999-08-05 2006-03-21 Regents Of The University Of Minnesota Multiponent adult stem cells and methods for isolation
AU2006202072B2 (en) * 1999-08-05 2010-12-09 Abt Holding Company Multipotent adult stem cells and methods for isolation
US8252280B1 (en) 1999-08-05 2012-08-28 Regents Of The University Of Minnesota MAPC generation of muscle
US10638734B2 (en) 2004-01-05 2020-05-05 Abt Holding Company Multipotent adult stem cells, sources thereof, methods of obtaining and maintaining same, methods of differentiation thereof, methods of use thereof and cells derived thereof
EP1103615A1 (en) * 1999-11-25 2001-05-30 Universite De Geneve Vectors capable of immortalizing non-dividing cells and cells immortalized with said vectors
FR2810046B1 (en) * 2000-06-07 2004-09-10 Neurotech PROCESS FOR CONDITIONAL IMMORTALIZATION OF CELLS AND PROTEIN CONSTRUCTIONS FOR ITS IMPLEMENTATION
US20020045219A1 (en) * 2000-08-02 2002-04-18 Whitehead Institute For Biomedical Research Production of human monoclonal antibodies
US6686159B2 (en) 2000-08-24 2004-02-03 Sierra Sciences, Inc. Methods and compositions for modulating telomerase reverse transcriptase (TERT) expression
EP1367899A4 (en) 2001-02-14 2004-07-28 Leo T Furcht Multipotent adult stem cells, sources thereof, methods of obtaining and maintaining same, methods of differentiation thereof, methods of use thereof and cells derived thereof
US7211435B2 (en) 2001-06-21 2007-05-01 Sierra Sciences, Inc. Telomerase expression repressor proteins and methods of using the same
WO2003066839A1 (en) * 2002-02-05 2003-08-14 Rappaport Family Institute For Research In The Medical Sciences Lineage committed stem cells selected for telomerase promoter activity
AU2003298016A1 (en) 2002-11-27 2004-06-23 Regents Of The University Of Minnesota Homologous recombination in multipotent adult progenitor cells
AP2280A (en) 2003-06-23 2011-10-31 Geron Corp Compositions and methods for increasing telomeraseactivity.
WO2005000248A2 (en) 2003-06-25 2005-01-06 Geron Corporation Compositions and methods for skin conditioning
WO2005003320A2 (en) 2003-07-02 2005-01-13 Regents Of The University Of Minnesota Neuronal differentiation of stem cells
EP1941032A2 (en) 2005-10-14 2008-07-09 Regents Of The University Of Minnesota Differentiation of non-embryonic stem cells to cells having a pancreatic phenotype
CA2670497A1 (en) 2006-11-24 2008-05-29 Regents Of The University Of Minnesota Endodermal progenitor cells
EP2245141B1 (en) 2008-01-18 2018-03-14 Regents of the University of Minnesota Stem cell aggregates and methods for making and using
EP2362899A1 (en) 2008-10-31 2011-09-07 Katholieke Universiteit Leuven Optimized methods for differentiation of cells into cells with hepatocyte and hepatocyte progenitor phenotypes, cells produced by the methods, and methods for using the cells
KR20110136825A (en) * 2009-03-09 2011-12-21 바이오아트라, 엘엘씨 Mirac proteins
JP5830013B2 (en) 2009-05-18 2015-12-09 テロメレイズ アクティベイション サイエンシズ,インコーポレーテッド Compositions and methods for increasing telomerase activity
EP3581649A1 (en) 2010-02-16 2019-12-18 Ultimovacs ASA Polypeptides
WO2011143415A1 (en) 2010-05-12 2011-11-17 Abt Holding Company Modulation of splenocytes in cell therapy
WO2011158125A2 (en) 2010-06-17 2011-12-22 Katholieke Universiteit Leuven Methods for differentiating cells into hepatic stellate cells and hepatic sinusoidal endothelial cells, cells produced by the methods, and methods for using the cells
EP2402038B1 (en) * 2010-07-02 2016-05-25 Fundación Centro Nacional De Investigaciones Oncológicas Carlos III Telomerase reverse transcriptase for protection against ageing
WO2012027474A1 (en) 2010-08-24 2012-03-01 Regents Of The University Of Minnesota Non-static suspension culture of cell aggregates
CA2909267C (en) 2013-04-12 2022-10-25 Saverio LA FRANCESCA Improving organs for transplantation
CN114657281A (en) * 2020-12-22 2022-06-24 中国科学院动物研究所 Endogenous virus as marker of aging degree and application of endogenous virus as aging intervention target
CN114601747A (en) * 2022-03-07 2022-06-10 广州市万千粉丝化妆品有限公司 Application of nucleoprotein telomerase with functions of promoting growth of protein and RNA, prolonging cell telomere and proliferating in cosmetics
WO2024075819A1 (en) * 2022-10-07 2024-04-11 Agc株式会社 Virus vector production method employing cell

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5830644A (en) * 1992-05-13 1998-11-03 Geron Corporation Method for screening for agents which increase telomerase activity in a cell
WO1995013382A1 (en) * 1993-11-12 1995-05-18 Geron Corporation Therapy and diagnosis of conditions related to telomere length and/or telomerase activity
CA2221602A1 (en) * 1995-06-07 1996-12-19 Cold Spring Harbor Laboratory Essential oligonucleotides of vertebrate telomerase

Also Published As

Publication number Publication date
AU759437B2 (en) 2003-04-17
WO1999035243A2 (en) 1999-07-15
WO1999035243A9 (en) 1999-10-28
EP1045697A2 (en) 2000-10-25
JP2002500040A (en) 2002-01-08
WO1999035243A3 (en) 1999-09-16
CA2315265A1 (en) 1999-07-15
AU2317299A (en) 1999-07-26

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