EA200400549A1 - Лечение сепсиса введением малых доз ингибитора пути тканевого фактора (tfpi) - Google Patents

Лечение сепсиса введением малых доз ингибитора пути тканевого фактора (tfpi)

Info

Publication number
EA200400549A1
EA200400549A1 EA200400549A EA200400549A EA200400549A1 EA 200400549 A1 EA200400549 A1 EA 200400549A1 EA 200400549 A EA200400549 A EA 200400549A EA 200400549 A EA200400549 A EA 200400549A EA 200400549 A1 EA200400549 A1 EA 200400549A1
Authority
EA
Eurasian Patent Office
Prior art keywords
tfpi
sepsis
tissue factor
introduction
treatment
Prior art date
Application number
EA200400549A
Other languages
English (en)
Inventor
Эбла А. Кризи
Original Assignee
Чирон Корпорейшн
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Чирон Корпорейшн filed Critical Чирон Корпорейшн
Publication of EA200400549A1 publication Critical patent/EA200400549A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y10/00—Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/57—Protease inhibitors from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nanotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Theoretical Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Mathematical Physics (AREA)
  • Physics & Mathematics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Способы профилактического или терапевтического лечения сепсиса или септического шока, включающие введение ингибитора пути тканевого фактора (TFPI) или аналога TFPI пациентам, страдающим сепсисом или другими воспалительными состояниями. Указанные способы включают применение непрерывной внутривенной инфузии TFPI или аналога TFPI в малых дозах, чтобы избежать неблагоприятных побочных эффектов.Отчет о международном поиске был опубликован 2004.03.04.
EA200400549A 2001-10-15 2002-10-15 Лечение сепсиса введением малых доз ингибитора пути тканевого фактора (tfpi) EA200400549A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32880601P 2001-10-15 2001-10-15
PCT/US2002/032625 WO2003055442A2 (en) 2001-10-15 2002-10-15 Treatment of sepsis by low dose administration of tissue factor pathway inhibitor (tfpi)

Publications (1)

Publication Number Publication Date
EA200400549A1 true EA200400549A1 (ru) 2005-02-24

Family

ID=23282520

Family Applications (2)

Application Number Title Priority Date Filing Date
EA200400549A EA200400549A1 (ru) 2001-10-15 2002-10-15 Лечение сепсиса введением малых доз ингибитора пути тканевого фактора (tfpi)
EA200400548A EA200400548A1 (ru) 2001-10-15 2002-10-15 Лечение тяжёлой пневмонии путём введения ингибитора пути тканевого фактора (tfpi)

Family Applications After (1)

Application Number Title Priority Date Filing Date
EA200400548A EA200400548A1 (ru) 2001-10-15 2002-10-15 Лечение тяжёлой пневмонии путём введения ингибитора пути тканевого фактора (tfpi)

Country Status (17)

Country Link
US (2) US7674769B2 (ru)
EP (2) EP1446140A4 (ru)
JP (5) JP2005515214A (ru)
KR (2) KR20040040489A (ru)
CN (2) CN1604787A (ru)
AU (2) AU2002365131B2 (ru)
BR (2) BR0213292A (ru)
CA (2) CA2463655A1 (ru)
EA (2) EA200400549A1 (ru)
HU (2) HUP0500472A2 (ru)
IL (2) IL161408A0 (ru)
IS (2) IS7224A (ru)
MX (2) MXPA04003547A (ru)
NO (2) NO20041996D0 (ru)
PL (2) PL372138A1 (ru)
WO (2) WO2003032904A2 (ru)
ZA (2) ZA200403601B (ru)

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Also Published As

Publication number Publication date
WO2003032904A3 (en) 2004-03-04
IL161407A0 (en) 2004-09-27
JP2005515214A (ja) 2005-05-26
AU2002340183B2 (en) 2008-11-13
IS7224A (is) 2004-04-15
HUP0500472A2 (hu) 2005-08-29
ZA200403690B (en) 2005-03-08
US7674769B2 (en) 2010-03-09
BR0213292A (pt) 2006-05-23
NO20041997D0 (no) 2004-05-14
JP2010006839A (ja) 2010-01-14
EA200400548A1 (ru) 2005-06-30
MXPA04003547A (es) 2004-07-22
JP2006008704A (ja) 2006-01-12
EP1446138A4 (en) 2007-03-14
EP1446138A2 (en) 2004-08-18
WO2003055442A2 (en) 2003-07-10
EP1446140A2 (en) 2004-08-18
ZA200403601B (en) 2006-06-28
JP2005506345A (ja) 2005-03-03
CA2463738A1 (en) 2003-07-10
IL161408A0 (en) 2004-09-27
WO2003055442A3 (en) 2004-03-04
KR20040040489A (ko) 2004-05-12
CA2463655A1 (en) 2003-04-24
CN1604787A (zh) 2005-04-06
PL374506A1 (en) 2005-10-31
WO2003032904A2 (en) 2003-04-24
HUP0501111A2 (en) 2007-12-28
AU2002365131A1 (en) 2003-07-15
NO20041996D0 (no) 2004-05-14
PL372138A1 (en) 2005-07-11
EP1446140A4 (en) 2007-03-07
JP2006008706A (ja) 2006-01-12
AU2002365131B2 (en) 2007-03-01
MXPA04003548A (es) 2004-07-22
US20030139339A1 (en) 2003-07-24
KR20050036867A (ko) 2005-04-20
CN1604790A (zh) 2005-04-06
IS7223A (is) 2004-04-15
BR0213293A (pt) 2004-12-21
US20030139340A1 (en) 2003-07-24

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