EA200301121A1 - Тартраты 5,8,14-триазатетрацикло[10.3.1.02,11.04,9]гексадека-2(11),3,5,7,9-пентаена - Google Patents
Тартраты 5,8,14-триазатетрацикло[10.3.1.02,11.04,9]гексадека-2(11),3,5,7,9-пентаенаInfo
- Publication number
- EA200301121A1 EA200301121A1 EA200301121A EA200301121A EA200301121A1 EA 200301121 A1 EA200301121 A1 EA 200301121A1 EA 200301121 A EA200301121 A EA 200301121A EA 200301121 A EA200301121 A EA 200301121A EA 200301121 A1 EA200301121 A1 EA 200301121A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- polymorphs
- hexadeca
- tartrate
- present
- relates
- Prior art date
Links
- FEWJPZIEWOKRBE-JCYAYHJZSA-L L-tartrate(2-) Chemical compound [O-]C(=O)[C@H](O)[C@@H](O)C([O-])=O FEWJPZIEWOKRBE-JCYAYHJZSA-L 0.000 abstract 3
- FEWJPZIEWOKRBE-LWMBPPNESA-L D-tartrate(2-) Chemical compound [O-]C(=O)[C@@H](O)[C@H](O)C([O-])=O FEWJPZIEWOKRBE-LWMBPPNESA-L 0.000 abstract 1
- FEWJPZIEWOKRBE-XIXRPRMCSA-N Mesotartaric acid Chemical compound OC(=O)[C@@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-XIXRPRMCSA-N 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 150000003892 tartrate salts Chemical class 0.000 abstract 1
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
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Abstract
Настоящее изобретение относится к тартратам 5,8,14-триазатетрацикло[10.3.1.0.0]гексадека-2(11),3,5,7,9-пентаена формулы (1) и фармацевтическим композициям, содержащим указанные вещества. Настоящее изобретение, в частности, относится к L-тартрату и полиморфам L-тартрата, включающим два разных безводных полиморфа (определяемые как формы A и B) и гидратный полиморф (определяемый как форма C). Кроме того, настоящее изобретение относится к D-тартрату 5,8,14-триазатетрацикло[10.3.1.0.0]гексадека-2(11),3,5,7,9-пентаена и его полиморфам, D,L-тартрату и его полиморфам и мезотартрату и его полиморфам.Международная заявка была опубликована вместе с отчетом о международном поиске.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US29086101P | 2001-05-14 | 2001-05-14 | |
PCT/IB2002/001437 WO2002092089A1 (en) | 2001-05-14 | 2002-04-26 | Tartrate salts of 5,8,14-triazatetracyclo {10.3.1.0?2,11.04,9¿}-hexadeca-2(11),3,5,7,9-pentaene and pharmaceutical compositions thereof |
Publications (2)
Publication Number | Publication Date |
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EA200301121A1 true EA200301121A1 (ru) | 2004-02-26 |
EA005528B1 EA005528B1 (ru) | 2005-04-28 |
Family
ID=23117845
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA200301121A EA005528B1 (ru) | 2001-05-14 | 2002-04-26 | Тартраты 5,8,14-триазатетрацикло[10.3.1.02,11.04,9]гексадека-2(11),3,5,7,9-пентаена |
Country Status (48)
Families Citing this family (44)
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IL137937A0 (en) * | 1999-08-27 | 2001-10-31 | Pfizer Prod Inc | A pharmaceutical composition for the prevention and treatment of nicotine addiction in a mammal |
YU34501A (sh) * | 2000-05-26 | 2003-10-31 | Pfizer Products Inc. | Postupak reaktivne kristalizacije radi povećanja veličine čestica |
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