EA036742B1 - ПРИМЕНЕНИЕ (R)-3-(6-р-ТОЛИЛ-ПИРИДИН-3-ИЛОКСИ)-1-A3А-БИЦИКЛО[2.2.2]ОКТАНА ДЛЯ ЛЕЧЕНИЯ, ПРЕДУПРЕЖДЕНИЯ ИЛИ ОТСРОЧКИ ПРОГРЕССИРОВАНИЯ ДИСКИНЕЗИИ, АССОЦИИРОВАННОЙ С ЛЕЧЕНИЕМ БОЛЕЗНИ ПАРКИНСОНА АГОНИСТОМ ДОПАМИНА - Google Patents

ПРИМЕНЕНИЕ (R)-3-(6-р-ТОЛИЛ-ПИРИДИН-3-ИЛОКСИ)-1-A3А-БИЦИКЛО[2.2.2]ОКТАНА ДЛЯ ЛЕЧЕНИЯ, ПРЕДУПРЕЖДЕНИЯ ИЛИ ОТСРОЧКИ ПРОГРЕССИРОВАНИЯ ДИСКИНЕЗИИ, АССОЦИИРОВАННОЙ С ЛЕЧЕНИЕМ БОЛЕЗНИ ПАРКИНСОНА АГОНИСТОМ ДОПАМИНА Download PDF

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Publication number
EA036742B1
EA036742B1 EA201200507A EA201200507A EA036742B1 EA 036742 B1 EA036742 B1 EA 036742B1 EA 201200507 A EA201200507 A EA 201200507A EA 201200507 A EA201200507 A EA 201200507A EA 036742 B1 EA036742 B1 EA 036742B1
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Eurasian Patent Office
Prior art keywords
treatment
levodopa
nachr
parkinson
disease
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EA201200507A
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English (en)
Russian (ru)
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EA201200507A1 (ru
Inventor
Тересе Ди-Паоло
Доминик Фойербах
Бальтазар Гомеш-Мансилла
Доналд Джонс
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Новартис Аг
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Application filed by Новартис Аг filed Critical Новартис Аг
Publication of EA201200507A1 publication Critical patent/EA201200507A1/ru
Publication of EA036742B1 publication Critical patent/EA036742B1/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EA201200507A 2009-09-22 2010-09-22 ПРИМЕНЕНИЕ (R)-3-(6-р-ТОЛИЛ-ПИРИДИН-3-ИЛОКСИ)-1-A3А-БИЦИКЛО[2.2.2]ОКТАНА ДЛЯ ЛЕЧЕНИЯ, ПРЕДУПРЕЖДЕНИЯ ИЛИ ОТСРОЧКИ ПРОГРЕССИРОВАНИЯ ДИСКИНЕЗИИ, АССОЦИИРОВАННОЙ С ЛЕЧЕНИЕМ БОЛЕЗНИ ПАРКИНСОНА АГОНИСТОМ ДОПАМИНА EA036742B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24465809P 2009-09-22 2009-09-22
PCT/EP2010/063946 WO2011036167A1 (en) 2009-09-22 2010-09-22 Use of nicotinic acetylcholine receptor alpha 7 activators

Publications (2)

Publication Number Publication Date
EA201200507A1 EA201200507A1 (ru) 2012-10-30
EA036742B1 true EA036742B1 (ru) 2020-12-15

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EA201200507A EA036742B1 (ru) 2009-09-22 2010-09-22 ПРИМЕНЕНИЕ (R)-3-(6-р-ТОЛИЛ-ПИРИДИН-3-ИЛОКСИ)-1-A3А-БИЦИКЛО[2.2.2]ОКТАНА ДЛЯ ЛЕЧЕНИЯ, ПРЕДУПРЕЖДЕНИЯ ИЛИ ОТСРОЧКИ ПРОГРЕССИРОВАНИЯ ДИСКИНЕЗИИ, АССОЦИИРОВАННОЙ С ЛЕЧЕНИЕМ БОЛЕЗНИ ПАРКИНСОНА АГОНИСТОМ ДОПАМИНА

Country Status (22)

Country Link
US (3) US10537539B2 (enExample)
EP (1) EP2480228B1 (enExample)
JP (2) JP6178074B2 (enExample)
KR (1) KR20120068878A (enExample)
CN (2) CN102573830A (enExample)
AU (1) AU2010299967B2 (enExample)
BR (1) BR112012006346A2 (enExample)
CA (1) CA2774801C (enExample)
CL (1) CL2012000702A1 (enExample)
EA (1) EA036742B1 (enExample)
ES (1) ES2614930T3 (enExample)
IL (1) IL218299A (enExample)
JO (1) JO3250B1 (enExample)
MA (1) MA33590B1 (enExample)
MX (1) MX359011B (enExample)
NZ (1) NZ598316A (enExample)
PH (1) PH12012500554A1 (enExample)
SG (1) SG178832A1 (enExample)
TN (1) TN2012000082A1 (enExample)
TW (1) TWI558398B (enExample)
WO (1) WO2011036167A1 (enExample)
ZA (1) ZA201201066B (enExample)

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WO2014203150A1 (en) 2013-06-17 2014-12-24 Lupin Limited Pyrrole derivatives as alpha 7 nachr modulators
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