MA33590B1 - Utilisation d'activateurs du récepteur nicotinique de l'acétylcholine alpha7 - Google Patents
Utilisation d'activateurs du récepteur nicotinique de l'acétylcholine alpha7Info
- Publication number
- MA33590B1 MA33590B1 MA34696A MA34696A MA33590B1 MA 33590 B1 MA33590 B1 MA 33590B1 MA 34696 A MA34696 A MA 34696A MA 34696 A MA34696 A MA 34696A MA 33590 B1 MA33590 B1 MA 33590B1
- Authority
- MA
- Morocco
- Prior art keywords
- acetylcholine
- tonic
- nicotine
- alpha
- reception
- Prior art date
Links
- OIPILFWXSMYKGL-UHFFFAOYSA-N acetylcholine Chemical compound CC(=O)OCC[N+](C)(C)C OIPILFWXSMYKGL-UHFFFAOYSA-N 0.000 title abstract 2
- 229960004373 acetylcholine Drugs 0.000 title abstract 2
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 title 1
- 229960002715 nicotine Drugs 0.000 title 1
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 title 1
- 230000001256 tonic effect Effects 0.000 title 1
- 208000012661 Dyskinesia Diseases 0.000 abstract 1
- 208000018737 Parkinson disease Diseases 0.000 abstract 1
- 238000011292 agonist therapy Methods 0.000 abstract 1
- 229940052760 dopamine agonists Drugs 0.000 abstract 1
- 239000003136 dopamine receptor stimulating agent Substances 0.000 abstract 1
- 108091006084 receptor activators Proteins 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24465809P | 2009-09-22 | 2009-09-22 | |
| PCT/EP2010/063946 WO2011036167A1 (en) | 2009-09-22 | 2010-09-22 | Use of nicotinic acetylcholine receptor alpha 7 activators |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA33590B1 true MA33590B1 (fr) | 2012-09-01 |
Family
ID=42990156
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA34696A MA33590B1 (fr) | 2009-09-22 | 2012-03-16 | Utilisation d'activateurs du récepteur nicotinique de l'acétylcholine alpha7 |
Country Status (22)
| Country | Link |
|---|---|
| US (3) | US10537539B2 (enExample) |
| EP (1) | EP2480228B1 (enExample) |
| JP (2) | JP6178074B2 (enExample) |
| KR (1) | KR20120068878A (enExample) |
| CN (2) | CN110051670A (enExample) |
| AU (1) | AU2010299967B2 (enExample) |
| BR (1) | BR112012006346A2 (enExample) |
| CA (1) | CA2774801C (enExample) |
| CL (1) | CL2012000702A1 (enExample) |
| EA (1) | EA036742B1 (enExample) |
| ES (1) | ES2614930T3 (enExample) |
| IL (1) | IL218299A (enExample) |
| JO (1) | JO3250B1 (enExample) |
| MA (1) | MA33590B1 (enExample) |
| MX (1) | MX359011B (enExample) |
| NZ (1) | NZ598316A (enExample) |
| PH (1) | PH12012500554A1 (enExample) |
| SG (1) | SG178832A1 (enExample) |
| TN (1) | TN2012000082A1 (enExample) |
| TW (1) | TWI558398B (enExample) |
| WO (1) | WO2011036167A1 (enExample) |
| ZA (1) | ZA201201066B (enExample) |
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| JO3250B1 (ar) * | 2009-09-22 | 2018-09-16 | Novartis Ag | إستعمال منشطات مستقبل نيكوتينيك أسيتيل كولين ألفا 7 |
| ES2570657T3 (es) | 2010-05-17 | 2016-05-19 | Forum Pharmaceuticals Inc | Una forma cristalina de hidrocloruro de (R)-7-cloro-n-(quinuclidin-3-il)benzo[b]tiofeno-2-carboxamida monohidrato |
| AU2012210652B2 (en) * | 2011-01-27 | 2016-04-07 | Novartis Ag | Use of nicotinic acetylcholine receptor alpha 7 activators |
| MX344701B (es) | 2011-02-03 | 2017-01-03 | Lupin Ltd | Derivados de pirrol como moduladores de nachr alfa 7. |
| EP2678327B9 (en) | 2011-02-23 | 2016-12-28 | Lupin Limited | Heteroaryl derivatives as alpha7 nachr modulators |
| KR20140018286A (ko) * | 2011-03-18 | 2014-02-12 | 노파르티스 아게 | 파킨슨병에서의 도파민 유발 이상운동증에서 사용하기 위한 알파 7 니코틴성 아세틸콜린 수용체 활성화제 및 mGluR5 길항제의 조합물 |
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| CA2852268C (en) * | 2011-10-20 | 2020-08-25 | Novartis Ag | Biomarkers predictive of responsiveness to alpha 7 nicotinic acetylcholine receptor activator treatment |
| NZ629453A (en) | 2012-03-06 | 2016-04-29 | Lupin Ltd | Thiazole derivatives as alpha 7 nachr modulators |
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