AU2010299967B2 - Use of nicotinic acetylcholine receptor alpha 7 activators - Google Patents

Use of nicotinic acetylcholine receptor alpha 7 activators Download PDF

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Publication number
AU2010299967B2
AU2010299967B2 AU2010299967A AU2010299967A AU2010299967B2 AU 2010299967 B2 AU2010299967 B2 AU 2010299967B2 AU 2010299967 A AU2010299967 A AU 2010299967A AU 2010299967 A AU2010299967 A AU 2010299967A AU 2010299967 B2 AU2010299967 B2 AU 2010299967B2
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bicyclo
aza
yloxy
octane
indol
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AU2010299967A1 (en
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Therese Di Paolo
Dominik Feuerbach
Baltazar Gomez-Mancilla
Donald Johns
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Novartis AG
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Novartis AG
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2010299967A 2009-09-22 2010-09-22 Use of nicotinic acetylcholine receptor alpha 7 activators Active AU2010299967B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24465809P 2009-09-22 2009-09-22
US61/244,658 2009-09-22
PCT/EP2010/063946 WO2011036167A1 (en) 2009-09-22 2010-09-22 Use of nicotinic acetylcholine receptor alpha 7 activators

Publications (2)

Publication Number Publication Date
AU2010299967A1 AU2010299967A1 (en) 2012-03-08
AU2010299967B2 true AU2010299967B2 (en) 2014-03-13

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AU2010299967A Active AU2010299967B2 (en) 2009-09-22 2010-09-22 Use of nicotinic acetylcholine receptor alpha 7 activators

Country Status (22)

Country Link
US (3) US10537539B2 (enExample)
EP (1) EP2480228B1 (enExample)
JP (2) JP6178074B2 (enExample)
KR (1) KR20120068878A (enExample)
CN (2) CN110051670A (enExample)
AU (1) AU2010299967B2 (enExample)
BR (1) BR112012006346A2 (enExample)
CA (1) CA2774801C (enExample)
CL (1) CL2012000702A1 (enExample)
EA (1) EA036742B1 (enExample)
ES (1) ES2614930T3 (enExample)
IL (1) IL218299A (enExample)
JO (1) JO3250B1 (enExample)
MA (1) MA33590B1 (enExample)
MX (1) MX359011B (enExample)
NZ (1) NZ598316A (enExample)
PH (1) PH12012500554A1 (enExample)
SG (1) SG178832A1 (enExample)
TN (1) TN2012000082A1 (enExample)
TW (1) TWI558398B (enExample)
WO (1) WO2011036167A1 (enExample)
ZA (1) ZA201201066B (enExample)

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US8729263B2 (en) * 2012-08-13 2014-05-20 Novartis Ag 1,4-disubstituted pyridazine analogs there of and methods for treating SMN-deficiency-related conditions
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BR112015016992A8 (pt) * 2013-01-15 2018-01-23 Novartis Ag uso de agonistas do receptor alfa 7 nicotínico de acetilcolina
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TW201446243A (zh) 2013-06-03 2014-12-16 Lupin Ltd 4-(5-(4-氯苯基)-2-(2-環丙基乙醯基)-1,4-二甲基-1氫-吡咯-3-基)苯磺醯胺作為α7尼古丁乙醯膽鹼受體調節劑
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AU2015362790A1 (en) 2014-12-16 2017-07-20 Axovant Sciences Gmbh Geminal substituted quinuclidine amide compounds as agonists of alpha-7 nicotinic acetylcholine receptors
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