EA023938B1 - Вектор гена - Google Patents
Вектор гена Download PDFInfo
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- EA023938B1 EA023938B1 EA201171335A EA201171335A EA023938B1 EA 023938 B1 EA023938 B1 EA 023938B1 EA 201171335 A EA201171335 A EA 201171335A EA 201171335 A EA201171335 A EA 201171335A EA 023938 B1 EA023938 B1 EA 023938B1
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- cell
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- mirna
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| RU2749971C2 (ru) * | 2016-09-22 | 2021-06-21 | Юниверсити Оф Массачусетс | Средство лечения болезни гентингтона на основе aav |
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| US9987309B2 (en) * | 2010-07-08 | 2018-06-05 | Duke University | Direct reprogramming of cells to cardiac myocyte fate |
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| WO2013152230A1 (en) * | 2012-04-04 | 2013-10-10 | The Trustees Of Columbia University In The City Of New York | Smooth muscle specific inhibition for anti-restenotic therapy |
| FI3597749T3 (fi) | 2012-05-25 | 2023-10-09 | Univ California | Menetelmiä ja koostumuksia rna-ohjattua kohde-dna-modifikaatiota varten ja rna-ohjattua transkription modulaatiota varten |
| WO2014011901A2 (en) * | 2012-07-11 | 2014-01-16 | Sangamo Biosciences, Inc. | Methods and compositions for delivery of biologics |
| PT3363902T (pt) | 2012-12-06 | 2019-12-19 | Sigma Aldrich Co Llc | Modificação e regulação de genoma baseadas em crispr |
| LT2956477T (lt) | 2013-02-15 | 2021-02-10 | Bioverativ Therapeutics Inc. | Optimizuotas faktoriaus viii genas |
| AU2014235794A1 (en) | 2013-03-14 | 2015-10-22 | Caribou Biosciences, Inc. | Compositions and methods of nucleic acid-targeting nucleic acids |
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| EP3160478A4 (en) | 2014-06-30 | 2018-05-16 | Bioverativ Therapeutics Inc. | Optimized factor ix gene |
| WO2016171235A1 (ja) * | 2015-04-22 | 2016-10-27 | 国立大学法人京都大学 | 組織細胞の選別方法 |
| US20180327820A1 (en) * | 2015-06-15 | 2018-11-15 | Murdoch Childrens Research Institute | Method of measuring chimerism |
| CA3001003A1 (en) | 2015-10-05 | 2017-04-13 | Modernatx, Inc. | Methods for therapeutic administration of messenger ribonucleic acid drugs |
| US10188750B1 (en) * | 2015-10-23 | 2019-01-29 | University Of South Florida | Self-replicating cell selective gene delivery compositions, methods, and uses thereof |
| PL3411478T3 (pl) | 2016-02-01 | 2022-10-03 | Bioverativ Therapeutics Inc. | Geny zoptymalizowanego czynnika VIII |
| GB201612214D0 (en) | 2016-07-14 | 2016-08-31 | Univ Oxford Innovation Ltd | Method |
| BR112019007982A2 (pt) * | 2016-10-18 | 2019-07-02 | Univ Oregon Health & Science | vetores de citomegalovírus elicitando células t restringidas por moléculas do complexo de histocompatibilidade e principal |
| CN106566838B (zh) * | 2016-11-14 | 2019-11-01 | 上海伯豪生物技术有限公司 | 一种基于CRISPR-Cas9技术的miR-126全长基因敲除试剂盒及其应用 |
| FI3612624T3 (fi) * | 2017-04-21 | 2024-12-04 | Ospedale San Raffaele Srl | Geeniterapia |
| IT201700086403A1 (it) * | 2017-07-27 | 2019-01-27 | Univ Del Piemonte Orientale | Endothelial-specific promoter sequences and uses thereof |
| JP7374883B2 (ja) | 2017-08-09 | 2023-11-07 | バイオベラティブ セラピューティクス インコーポレイテッド | 核酸分子およびその使用 |
| WO2019152692A1 (en) | 2018-02-01 | 2019-08-08 | Bioverativ Therapeutics, Inc. | Use of lentiviral vectors expressing factor viii |
| CN119955796A (zh) | 2018-08-09 | 2025-05-09 | 比奥维拉迪维治疗股份有限公司 | 核酸分子及其用于非病毒基因疗法的用途 |
| BR112021010047A2 (pt) | 2018-12-06 | 2021-08-24 | Bioverativ Therapeutics Inc. | Uso de vetores lentivirais expressando o fator ix |
| CN115279896A (zh) | 2019-09-30 | 2022-11-01 | 比奥维拉迪维治疗股份有限公司 | 慢病毒载体配制品 |
| KR20220097487A (ko) * | 2019-11-12 | 2022-07-07 | 더 리전트 오브 더 유니버시티 오브 캘리포니아 | X-연관 만성 육아종 질환을 치료하기 위한 조혈 줄기 세포에서의 렌티바이러스 벡터 |
| MX2023000156A (es) | 2020-06-24 | 2023-02-16 | Bioverativ Therapeutics Inc | Metodos para la eliminacion de factor viii libre de preparaciones de vectores lentivirales modificados para expresar dicha proteina. |
| CA3189673A1 (en) | 2020-08-23 | 2022-03-03 | Ajay MAGHODIA | Modified baculovirus system for improved production of closed-ended dna (cedna) |
| EP4392443A1 (en) | 2021-08-23 | 2024-07-03 | Bioverativ Therapeutics Inc. | Optimized factor viii genes |
| AU2022334711A1 (en) | 2021-08-23 | 2024-04-04 | Bioverativ Therapeutics Inc. | Baculovirus expression system |
| CN115725656A (zh) * | 2021-09-01 | 2023-03-03 | 联邦生物科技(珠海横琴)有限公司 | 一种以细胞质rna病毒为载体递送干扰rna的方法 |
| CA3232988A1 (en) | 2021-09-30 | 2023-04-06 | Bioverativ Therapeutics Inc. | Nucleic acids encoding factor viii polypeptides with reduced immunogenicity |
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| WO2025122739A1 (en) * | 2023-12-05 | 2025-06-12 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Compositions and methods for treating a heart disease |
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| US11046957B2 (en) | 2016-09-22 | 2021-06-29 | University Of Massachusetts | AAV treatment of Huntington's disease |
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