EA017582B1 - Лечение метастатической стадии рака предстательной железы дегареликсом - Google Patents
Лечение метастатической стадии рака предстательной железы дегареликсом Download PDFInfo
- Publication number
- EA017582B1 EA017582B1 EA200901074A EA200901074A EA017582B1 EA 017582 B1 EA017582 B1 EA 017582B1 EA 200901074 A EA200901074 A EA 200901074A EA 200901074 A EA200901074 A EA 200901074A EA 017582 B1 EA017582 B1 EA 017582B1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- subject
- degarelix
- treatment
- level
- days
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Oncology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2774108P | 2008-02-11 | 2008-02-11 | |
| EP08250703 | 2008-02-29 | ||
| US14795609P | 2009-01-28 | 2009-01-28 | |
| PCT/IB2009/000370 WO2009101533A1 (en) | 2008-02-11 | 2009-02-10 | Treatment of metastatic stage prostate cancer with degarelix |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA200901074A1 EA200901074A1 (ru) | 2010-04-30 |
| EA017582B1 true EA017582B1 (ru) | 2013-01-30 |
Family
ID=39718285
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200901074A EA017582B1 (ru) | 2008-02-11 | 2009-02-10 | Лечение метастатической стадии рака предстательной железы дегареликсом |
| EA201300742A EA026521B1 (ru) | 2008-02-11 | 2009-02-10 | СПОСОБ ЛЕЧЕНИЯ РАКА ПРЕДСТАТЕЛЬНОЙ ЖЕЛЕЗЫ АНТАГОНИСТОМ ГОНАДОТРОПИН-ВЫСВОБОЖДАЮЩЕГО ГОРМОНА (GnRH) ДЕГАРЕЛИКСОМ |
| EA201300741A EA036695B1 (ru) | 2008-02-11 | 2009-02-10 | Применение композиции, содержащей дегареликс, для лечения рака предстательной железы у субъекта, имеющего повышенный уровень холестерина |
| EA200901075A EA020543B1 (ru) | 2008-02-11 | 2009-02-10 | СПОСОБ ЛЕЧЕНИЯ РАКА ПРЕДСТАТЕЛЬНОЙ ЖЕЛЕЗЫ АНТАГОНИСТОМ ГОНАДОТРОПИН-ВЫСВОБОЖДАЮЩЕГО ГОРМОНА (GnRH) ДЕГАРЕЛИКСОМ |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201300742A EA026521B1 (ru) | 2008-02-11 | 2009-02-10 | СПОСОБ ЛЕЧЕНИЯ РАКА ПРЕДСТАТЕЛЬНОЙ ЖЕЛЕЗЫ АНТАГОНИСТОМ ГОНАДОТРОПИН-ВЫСВОБОЖДАЮЩЕГО ГОРМОНА (GnRH) ДЕГАРЕЛИКСОМ |
| EA201300741A EA036695B1 (ru) | 2008-02-11 | 2009-02-10 | Применение композиции, содержащей дегареликс, для лечения рака предстательной железы у субъекта, имеющего повышенный уровень холестерина |
| EA200901075A EA020543B1 (ru) | 2008-02-11 | 2009-02-10 | СПОСОБ ЛЕЧЕНИЯ РАКА ПРЕДСТАТЕЛЬНОЙ ЖЕЛЕЗЫ АНТАГОНИСТОМ ГОНАДОТРОПИН-ВЫСВОБОЖДАЮЩЕГО ГОРМОНА (GnRH) ДЕГАРЕЛИКСОМ |
Country Status (25)
| Country | Link |
|---|---|
| US (17) | US20090203623A1 (https=) |
| EP (7) | EP2650012B1 (https=) |
| JP (12) | JP5924866B2 (https=) |
| KR (8) | KR20220009504A (https=) |
| CN (4) | CN101998861A (https=) |
| AU (2) | AU2009213751B2 (https=) |
| BR (2) | BRPI0908127A2 (https=) |
| CA (3) | CA2714445C (https=) |
| CY (3) | CY1115561T1 (https=) |
| DK (3) | DK2505204T3 (https=) |
| EA (4) | EA017582B1 (https=) |
| ES (3) | ES2532709T3 (https=) |
| HK (1) | HK1198243A1 (https=) |
| HR (3) | HRP20140665T1 (https=) |
| IL (3) | IL207295A (https=) |
| JO (1) | JOP20090061B1 (https=) |
| MX (2) | MX2010008817A (https=) |
| NZ (4) | NZ587057A (https=) |
| PL (3) | PL2505204T3 (https=) |
| PT (3) | PT2650012E (https=) |
| RU (2) | RU2504393C2 (https=) |
| SI (3) | SI2249859T1 (https=) |
| TW (2) | TWI539959B (https=) |
| WO (2) | WO2009101533A1 (https=) |
| ZA (1) | ZA201005697B (https=) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0117057D0 (en) * | 2001-07-12 | 2001-09-05 | Ferring Bv | Pharmaceutical composition |
| JO3525B1 (ar) * | 2008-02-11 | 2020-07-05 | Ferring Int Center Sa | علاج سرطان البروستاتا في المرحلة النقيلية بدواء ديجاريليكس |
| TWI539959B (zh) * | 2008-02-11 | 2016-07-01 | 菲瑞茵國際中心股份有限公司 | 治療轉移階段攝護腺癌的方法 |
| MX2011011431A (es) * | 2009-05-01 | 2012-02-23 | Ferring Bv | Composicion para el tratamiento de cancer de prostata. |
| TW201043221A (en) * | 2009-05-06 | 2010-12-16 | Ferring Int Ct Sa | Kit and method for preparation of a Degarelix solution |
| US20110039787A1 (en) * | 2009-07-06 | 2011-02-17 | Ferring International Center S.A. | Compositions, kits and methods for treating benign prostate hyperplasia |
| FR2964323B1 (fr) * | 2010-09-08 | 2012-11-09 | Jean Pierre Raynaud | Utilisation de la testosterone chez un patient en deficit androgenique et atteint d'un cancer de la prostate |
| LT2632934T (lt) | 2010-10-27 | 2017-01-10 | Ferring B.V. | Degarelikso ir jo tarpinių darinių gamybos būdas |
| EP2447276A1 (en) | 2010-10-27 | 2012-05-02 | Ferring B.V. | Process for the manufacture of Degarelix and its intermediates |
| JO3755B1 (ar) | 2011-01-26 | 2021-01-31 | Ferring Bv | تركيبات تستوستيرون |
| AU2012225232B2 (en) | 2011-03-09 | 2016-05-12 | Richard G. Pestell | Prostate cancer cell lines, gene signatures and uses thereof |
| CN102204889B (zh) * | 2011-05-23 | 2013-09-18 | 蚌埠丰原涂山制药有限公司 | 一种醋酸地加瑞克冻干粉针剂及其制备方法 |
| WO2013104745A1 (en) * | 2012-01-13 | 2013-07-18 | Ferring Bv | Pharmaceutical composition |
| JP6518585B2 (ja) | 2012-05-14 | 2019-05-22 | リチャード ジー. ペステル | がんの治療のためのccr5の修飾薬の使用 |
| PL4512390T1 (pl) | 2012-06-01 | 2025-09-01 | Ferring B.V. | Wytwarzanie degareliksu |
| NZ744456A (en) | 2012-09-26 | 2019-09-27 | Aragon Pharmaceuticals Inc | Anti-androgens for the treatment of non-metastatic castrate-resistant prostate cancer |
| PL2900675T3 (pl) | 2012-09-28 | 2019-08-30 | Takeda Pharmaceutical Company Limited | Sposób wytwarzania pochodnej tienopirymidyny |
| IL241595B2 (en) | 2013-03-15 | 2025-10-01 | Abbvie Inc | Composition for use in methods of treating heavy menstrual bleeding associated with uterine fibroids |
| WO2014186608A1 (en) * | 2013-05-15 | 2014-11-20 | Adverse Events, Inc. | System and method for surveillance and evaluation of safety risks associated with medical interventions |
| US10821152B2 (en) | 2014-08-26 | 2020-11-03 | Betanien Hospital | Methods, agents and compositions for treatment of inflammatory conditions |
| AU2016261770B2 (en) * | 2015-05-12 | 2022-06-02 | Drexel University | Compounds and compositions useful for treating or preventing cancer metastasis, and methods using same |
| CN110248661A (zh) | 2016-09-30 | 2019-09-17 | 梦欧文科学有限责任公司 | 前列腺癌的治疗 |
| BR112019014192A2 (pt) * | 2017-01-30 | 2020-02-11 | Antev Limited | Composição compreendendo pelo menos um antagonista de gnrh |
| US10702508B2 (en) | 2017-10-16 | 2020-07-07 | Aragon Pharmaceuticals, Inc. | Anti-androgens for the treatment of non-metastatic castration-resistant prostate cancer |
| AU2018419533A1 (en) | 2018-04-19 | 2020-11-12 | Abbvie Inc. | Methods of treating heavy menstrual bleeding |
| EP3829584A4 (en) * | 2018-08-01 | 2022-06-08 | Abbvie Inc. | DOSAGE SCHEDULES FOR ELAGOLIX |
| RU2731002C1 (ru) * | 2019-10-22 | 2020-08-26 | Государственное бюджетное учреждение здравоохранения Московской области "Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского" (ГБУЗ МО МОНИКИ им. М.Ф. Владимирского) | Способ лечения рака предстательной железы |
| CN116407494B (zh) * | 2023-03-02 | 2024-07-09 | 山东大学齐鲁医院 | 一种醋酸地加瑞克注射液及其制备方法、用途 |
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| US5296468A (en) | 1989-10-30 | 1994-03-22 | The Salk Institute For Biological Studies | GnRH analogs |
| DE69214818T2 (de) | 1991-04-25 | 1997-02-27 | Romano S.-Cergue Deghenghi | LHRH-Antagonisten |
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| CN1411803A (zh) | 2002-08-29 | 2003-04-23 | 四川大学 | 制备前体脂质体的方法及其装置 |
| BRPI0314546B8 (pt) | 2002-09-27 | 2021-05-25 | Zentaris Gmbh | composição de gel farmacêutico compreendendo peptídeos farmaceuticamente atvos com liberação sustentada, método para a produção dos mesmos kit. |
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| WO2006069779A1 (en) | 2004-12-30 | 2006-07-06 | F. Hoffmann-La Roche Ag | Preparing of peptides with excellent solubility |
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| EP1891964A1 (en) | 2006-08-08 | 2008-02-27 | AEterna Zentaris GmbH | Application of initial doses of LHRH analogues and maintenance doses of LHRH antagonists for the treatment of hormone-dependent cancers and corresponding pharmaceutical kits |
| EP1967202A1 (en) | 2007-03-05 | 2008-09-10 | AEterna Zentaris GmbH | Use of LHRH Antagonists for the Treatment of Lower Urinary Tract Symptoms, in particular Overactive Bladder and/or Detrusor Overactivity |
| IL182922A0 (en) | 2007-05-02 | 2007-09-20 | Medimop Medical Projects Ltd | Automatic liquid drug reconstitution apparatus |
| US8283331B2 (en) | 2007-10-09 | 2012-10-09 | Children's Medical Center Corporation | Methods to regulate miRNA processing by targeting Lin-28 |
| CA2711984A1 (en) | 2008-01-15 | 2009-07-23 | Abbott Gmbh & Co. Kg | Powdered protein compositions and methods of making same |
| TWI539959B (zh) | 2008-02-11 | 2016-07-01 | 菲瑞茵國際中心股份有限公司 | 治療轉移階段攝護腺癌的方法 |
| ES2589322T3 (es) | 2008-02-11 | 2016-11-11 | Safety Syringes, Inc. | Jeringa con protector de seguridad de aguja y clip para evitar la liberación del protector durante un proceso de reconstitución |
| WO2010121835A1 (en) | 2009-04-24 | 2010-10-28 | Polypeptide Laboratories A/S | Method for the manufacture of degarelix |
| MX2011011431A (es) | 2009-05-01 | 2012-02-23 | Ferring Bv | Composicion para el tratamiento de cancer de prostata. |
| TW201043221A (en) | 2009-05-06 | 2010-12-16 | Ferring Int Ct Sa | Kit and method for preparation of a Degarelix solution |
| US20110039787A1 (en) | 2009-07-06 | 2011-02-17 | Ferring International Center S.A. | Compositions, kits and methods for treating benign prostate hyperplasia |
| WO2011066386A1 (en) | 2009-11-25 | 2011-06-03 | Novetide, Ltd. | Process for production of degarelix |
| IT1399892B1 (it) | 2010-03-15 | 2013-05-09 | Spi Tecno Srl | Sistema per l illuminazione pubblica |
| ES2385240B1 (es) | 2010-07-26 | 2013-09-23 | Gp-Pharm, S.A. | Cápsulas de principios activos farmacéuticos y ácidos grasos poliinsaturados para el tratamiento de enfermedades de la próstata. |
| LT2632934T (lt) | 2010-10-27 | 2017-01-10 | Ferring B.V. | Degarelikso ir jo tarpinių darinių gamybos būdas |
| EP2447276A1 (en) | 2010-10-27 | 2012-05-02 | Ferring B.V. | Process for the manufacture of Degarelix and its intermediates |
| JO3755B1 (ar) | 2011-01-26 | 2021-01-31 | Ferring Bv | تركيبات تستوستيرون |
| CN102204889B (zh) | 2011-05-23 | 2013-09-18 | 蚌埠丰原涂山制药有限公司 | 一种醋酸地加瑞克冻干粉针剂及其制备方法 |
| KR20140063602A (ko) | 2011-07-15 | 2014-05-27 | 훼링 비.브이. | 피코설페이트 조성물을 투여하여 대장내시경의 시술 시기를 조절하는 방법 |
| PL4512390T1 (pl) | 2012-06-01 | 2025-09-01 | Ferring B.V. | Wytwarzanie degareliksu |
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2009
- 2009-02-09 TW TW098104073A patent/TWI539959B/zh active
- 2009-02-09 TW TW098104075A patent/TWI442932B/zh active
- 2009-02-09 JO JOP/2009/0061A patent/JOP20090061B1/ar active
- 2009-02-10 PL PL12165896T patent/PL2505204T3/pl unknown
- 2009-02-10 KR KR1020227000962A patent/KR20220009504A/ko not_active Ceased
- 2009-02-10 SI SI200930942T patent/SI2249859T1/sl unknown
- 2009-02-10 CN CN2009801127793A patent/CN101998861A/zh active Pending
- 2009-02-10 PT PT131684045T patent/PT2650012E/pt unknown
- 2009-02-10 MX MX2010008817A patent/MX2010008817A/es active IP Right Grant
- 2009-02-10 DK DK12165896T patent/DK2505204T3/da active
- 2009-02-10 EP EP13168404.5A patent/EP2650012B1/en not_active Revoked
- 2009-02-10 RU RU2010133481/15A patent/RU2504393C2/ru active
- 2009-02-10 RU RU2010133480/15A patent/RU2504394C2/ru active
- 2009-02-10 EA EA200901074A patent/EA017582B1/ru not_active IP Right Cessation
- 2009-02-10 KR KR1020107020035A patent/KR101542480B1/ko active Active
- 2009-02-10 EP EP09709538A patent/EP2249858A1/en not_active Ceased
- 2009-02-10 MX MX2010008816A patent/MX2010008816A/es active IP Right Grant
- 2009-02-10 CN CN200980104713XA patent/CN101939020B/zh not_active Ceased
- 2009-02-10 PT PT97113906T patent/PT2249859E/pt unknown
- 2009-02-10 NZ NZ587057A patent/NZ587057A/xx unknown
- 2009-02-10 DK DK09711390.6T patent/DK2249859T3/da active
- 2009-02-10 HR HRP20140665AT patent/HRP20140665T1/hr unknown
- 2009-02-10 SI SI200931181T patent/SI2650012T1/sl unknown
- 2009-02-10 ES ES12165896.7T patent/ES2532709T3/es active Active
- 2009-02-10 DK DK13168404.5T patent/DK2650012T3/da active
- 2009-02-10 KR KR1020187030959A patent/KR20180118830A/ko not_active Ceased
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