EA015706B1 - Моноклональное антитело или его фрагмент, связывающиеся с полипептидом il-22ra, гуманизированное антитело, полученное из указанного антитела, гибридомы, продуцирующие антитело, и применение указанного антитела - Google Patents
Моноклональное антитело или его фрагмент, связывающиеся с полипептидом il-22ra, гуманизированное антитело, полученное из указанного антитела, гибридомы, продуцирующие антитело, и применение указанного антитела Download PDFInfo
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- EA015706B1 EA015706B1 EA200700916A EA200700916A EA015706B1 EA 015706 B1 EA015706 B1 EA 015706B1 EA 200700916 A EA200700916 A EA 200700916A EA 200700916 A EA200700916 A EA 200700916A EA 015706 B1 EA015706 B1 EA 015706B1
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- antibody
- polypeptides
- polypeptide
- antibodies
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- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
- Y10S530/809—Fused cells, e.g. hybridoma
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| MXPA05010134A (es) * | 2003-03-24 | 2005-11-16 | Zymogenetics Inc | Anticuerpos anti-il-20, metodos y moleculas de enlace que se usan en la inflamacion. |
| JP4991307B2 (ja) * | 2003-11-21 | 2012-08-01 | ザイモジェネティクス, インコーポレイテッド | 抗il−20抗体および結合パートナーならびに炎症において用いる方法 |
| US7537761B2 (en) * | 2004-10-22 | 2009-05-26 | Zymogenetics, Inc. | Anti-IL-22RA antibodies and binding partners and methods of using in inflammation |
| EP1954719A2 (en) * | 2005-12-02 | 2008-08-13 | Genentech Inc. | Compositions and methods for the treatment of diseases and disorders associated with cytokine signaling involving antibodies that bind to il-22 and il-22r |
| WO2011047153A1 (en) * | 2009-10-15 | 2011-04-21 | President And Fellows Of Harvard College | Methods for modulating autoimmunity |
| PH12012500924A1 (en) | 2009-11-19 | 2012-11-26 | Merck Serono Sa | Humanized antibodies against human il-22ra |
| WO2011104381A2 (en) | 2010-02-26 | 2011-09-01 | Novo Nordisk A/S | Stable antibody containing compositions |
| CA2800188A1 (en) | 2010-05-28 | 2011-12-01 | Novo Nordisk A/S | Stable multi-dose compositions comprising an antibody and a preservative |
| AU2012204574B2 (en) | 2011-01-04 | 2017-05-11 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods of treating age-related macular degeneration |
| CA2828753C (en) | 2011-03-16 | 2022-07-26 | arGEN-X BV | Antibodies to cd70 |
| US8603470B1 (en) | 2012-08-07 | 2013-12-10 | National Cheng Kung University | Use of IL-20 antagonists for treating liver diseases |
| US10391168B1 (en) | 2014-08-22 | 2019-08-27 | University Of Bern | Anti-CD70 combination therapy |
| EP3442562B1 (en) * | 2016-04-15 | 2022-09-21 | Evive Biotechnology (Shanghai) Ltd | An il-22 dimer for use in treating necrotizing enterocolitis |
| EP3464357A1 (en) | 2016-05-24 | 2019-04-10 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and pharmaceutical compositions for the treatment of pulmonary bacterial infections |
| GB201612337D0 (en) | 2016-07-15 | 2016-08-31 | Argen-X N V | Ant-il-22r antibodies |
| WO2018097646A1 (ko) * | 2016-11-24 | 2018-05-31 | 이형근 | 질환의 진단용 조성물 |
| GB201800649D0 (en) | 2018-01-16 | 2018-02-28 | Argenx Bvba | CD70 Combination Therapy |
| WO2019236585A1 (en) | 2018-06-05 | 2019-12-12 | Bioatla, Llc | Anti-il-22 antibodies, antibody fragments, their immunoconjugates and uses thereof |
| CN110078832B (zh) * | 2019-04-18 | 2021-12-14 | 江南大学 | 一类基于ZZ domain的二抗及其制备方法和应用 |
| CN117425674A (zh) * | 2021-03-02 | 2024-01-19 | 丹娜法伯癌症研究院 | 治疗红细胞疾患的方法 |
| WO2024184333A1 (en) | 2023-03-08 | 2024-09-12 | Leo Pharma A/S | Il-22r antibody for use in treating atopic dermatitis |
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2005
- 2005-10-21 US US11/256,499 patent/US7537761B2/en active Active
- 2005-10-21 PT PT05816060T patent/PT1812476E/pt unknown
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- 2005-10-21 UA UAA200705409A patent/UA96122C2/ru unknown
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- 2005-10-21 ES ES05816060T patent/ES2347672T3/es not_active Expired - Lifetime
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- 2005-10-21 DE DE602005022475T patent/DE602005022475D1/de not_active Expired - Lifetime
- 2005-10-21 EP EP05816060A patent/EP1812476B1/en not_active Expired - Lifetime
- 2005-10-21 EA EA200700916A patent/EA015706B1/ru not_active IP Right Cessation
- 2005-10-21 DK DK05816060.7T patent/DK1812476T3/da active
- 2005-10-21 BR BRPI0516975-5A patent/BRPI0516975A/pt not_active IP Right Cessation
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2007
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- 2007-05-22 ZA ZA200704125A patent/ZA200704125B/xx unknown
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2009
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2010
- 2010-07-22 IL IL207146A patent/IL207146A/en not_active IP Right Cessation
- 2010-10-18 CY CY20101100932T patent/CY1110843T1/el unknown
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2012
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2013
- 2013-08-06 US US13/960,556 patent/US20130315919A1/en not_active Abandoned
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