EA009902B1 - Модуляторы рецепторов андрогенов - Google Patents

Модуляторы рецепторов андрогенов Download PDF

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Publication number
EA009902B1
EA009902B1 EA200601267A EA200601267A EA009902B1 EA 009902 B1 EA009902 B1 EA 009902B1 EA 200601267 A EA200601267 A EA 200601267A EA 200601267 A EA200601267 A EA 200601267A EA 009902 B1 EA009902 B1 EA 009902B1
Authority
EA
Eurasian Patent Office
Prior art keywords
hydroxy
trifluoromethylbenznitrile
hydroxyalkyl
thioalkyl
group
Prior art date
Application number
EA200601267A
Other languages
English (en)
Russian (ru)
Other versions
EA200601267A1 (ru
Inventor
Лейн-Ен Ху
Хуангсу Лей
Дэниел Юнлонг Ду
Брюс Аллен Лефкер
Original Assignee
УОРНЕР-ЛАМБЕРТ КОМПАНИ Эл-Эл-Си
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by УОРНЕР-ЛАМБЕРТ КОМПАНИ Эл-Эл-Си filed Critical УОРНЕР-ЛАМБЕРТ КОМПАНИ Эл-Эл-Си
Publication of EA200601267A1 publication Critical patent/EA200601267A1/ru
Publication of EA009902B1 publication Critical patent/EA009902B1/ru

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/49Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/54Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/275Nitriles; Isonitriles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/275Nitriles; Isonitriles
    • A61K31/277Nitriles; Isonitriles having a ring, e.g. verapamil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/08Antiseborrheics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28Antiandrogens
EA200601267A 2004-02-13 2005-01-31 Модуляторы рецепторов андрогенов EA009902B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US54473804P 2004-02-13 2004-02-13
US60564704P 2004-08-30 2004-08-30
PCT/IB2005/000229 WO2005080320A1 (en) 2004-02-13 2005-01-31 Androgen receptor modulators

Publications (2)

Publication Number Publication Date
EA200601267A1 EA200601267A1 (ru) 2006-12-29
EA009902B1 true EA009902B1 (ru) 2008-04-28

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
EA200601267A EA009902B1 (ru) 2004-02-13 2005-01-31 Модуляторы рецепторов андрогенов

Country Status (20)

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US (1) US7576128B2 (US07576128-20090818-C00009.png)
EP (1) EP1716110A1 (US07576128-20090818-C00009.png)
JP (1) JP3997255B2 (US07576128-20090818-C00009.png)
KR (1) KR100783255B1 (US07576128-20090818-C00009.png)
AP (1) AP2006003700A0 (US07576128-20090818-C00009.png)
AR (1) AR047606A1 (US07576128-20090818-C00009.png)
AU (1) AU2005214167B2 (US07576128-20090818-C00009.png)
BR (1) BRPI0507670A (US07576128-20090818-C00009.png)
CA (1) CA2554696C (US07576128-20090818-C00009.png)
CR (1) CR8555A (US07576128-20090818-C00009.png)
EA (1) EA009902B1 (US07576128-20090818-C00009.png)
EC (1) ECSP066761A (US07576128-20090818-C00009.png)
IL (1) IL176935A0 (US07576128-20090818-C00009.png)
MA (1) MA28361A1 (US07576128-20090818-C00009.png)
NO (1) NO20064053L (US07576128-20090818-C00009.png)
PA (1) PA8623501A1 (US07576128-20090818-C00009.png)
PE (1) PE20051168A1 (US07576128-20090818-C00009.png)
TW (1) TW200534842A (US07576128-20090818-C00009.png)
UY (1) UY28746A1 (US07576128-20090818-C00009.png)
WO (1) WO2005080320A1 (US07576128-20090818-C00009.png)

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BRPI0509759A (pt) 2004-04-13 2007-10-16 Warner Lambert Co moduladores de androgênio
WO2005102990A1 (en) 2004-04-22 2005-11-03 Warner-Lambert Company Llc Androgen modulators
JP4874965B2 (ja) 2004-07-08 2012-02-15 ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー アンドロゲン調節剤
US20080064745A1 (en) * 2004-08-18 2008-03-13 Warner-Lambert Company Llc Androgen Modulators
ES2302229T3 (es) * 2004-08-31 2008-07-01 Warner-Lambert Company Llc Moduladores de androgenos.
TW200724139A (en) 2005-05-05 2007-07-01 Warner Lambert Co Androgen modulators
TW200708499A (en) * 2005-06-22 2007-03-01 Warner Lambert Co Process for producing ethers
WO2007007149A1 (en) * 2005-07-12 2007-01-18 Warner-Lambert Company Llc Androgen modulators
US20090170886A1 (en) * 2005-08-08 2009-07-02 Pfizer Inc Androgen modulators
EP3108879A1 (en) 2015-06-25 2016-12-28 Cassiopea S.p.A. High concentration formulation
US20210292335A1 (en) * 2018-08-07 2021-09-23 Emory University Heterocyclic Flavone Derivatives, Compositions, and Methods Related Thereto

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Also Published As

Publication number Publication date
AU2005214167B2 (en) 2008-08-07
BRPI0507670A (pt) 2007-07-17
TW200534842A (en) 2005-11-01
UY28746A1 (es) 2005-09-30
IL176935A0 (en) 2006-12-10
KR100783255B1 (ko) 2007-12-06
PE20051168A1 (es) 2006-02-18
JP3997255B2 (ja) 2007-10-24
KR20060116223A (ko) 2006-11-14
CA2554696C (en) 2009-06-30
PA8623501A1 (es) 2005-08-30
US7576128B2 (en) 2009-08-18
CR8555A (es) 2006-10-17
AR047606A1 (es) 2006-01-25
MA28361A1 (fr) 2006-12-01
ECSP066761A (es) 2006-11-16
JP2007522199A (ja) 2007-08-09
NO20064053L (no) 2006-11-08
EA200601267A1 (ru) 2006-12-29
EP1716110A1 (en) 2006-11-02
CA2554696A1 (en) 2005-09-01
US20050182132A1 (en) 2005-08-18
AP2006003700A0 (en) 2006-08-31
AU2005214167A1 (en) 2005-09-01
WO2005080320A1 (en) 2005-09-01

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