EA007225B1 - Производные n-[фенил(пиперидин-2-ил)метил]бензамида и их применение в терапии - Google Patents
Производные n-[фенил(пиперидин-2-ил)метил]бензамида и их применение в терапии Download PDFInfo
- Publication number
- EA007225B1 EA007225B1 EA200401172A EA200401172A EA007225B1 EA 007225 B1 EA007225 B1 EA 007225B1 EA 200401172 A EA200401172 A EA 200401172A EA 200401172 A EA200401172 A EA 200401172A EA 007225 B1 EA007225 B1 EA 007225B1
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- EA
- Eurasian Patent Office
- Prior art keywords
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- general formula
- hydrogen atom
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- 239000003814 drug Substances 0.000 title claims abstract 3
- FYAFZECZBPTDGS-UHFFFAOYSA-N n-[phenyl(piperidin-2-yl)methyl]benzamide Chemical class C=1C=CC=CC=1C(=O)NC(C=1C=CC=CC=1)C1CCCCN1 FYAFZECZBPTDGS-UHFFFAOYSA-N 0.000 title 1
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- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims abstract description 11
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- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims abstract description 9
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- 125000001424 substituent group Chemical group 0.000 claims abstract description 6
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- 229910052757 nitrogen Inorganic materials 0.000 claims abstract description 4
- 125000004433 nitrogen atom Chemical group N* 0.000 claims abstract description 4
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Addiction (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0204916A FR2838739B1 (fr) | 2002-04-19 | 2002-04-19 | Derives de n-[phenyl(piperidin-2-yl)methyl)benzamide, leur preparation et leur application en therapeutique |
| PCT/FR2003/001232 WO2003089411A1 (fr) | 2002-04-19 | 2003-04-17 | Derives de n-[phenyl(piperidin-2-yl)methyl] benzamide, leur preparation et leur application en therapeutique |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA200401172A1 EA200401172A1 (ru) | 2005-04-28 |
| EA007225B1 true EA007225B1 (ru) | 2006-08-25 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200401172A EA007225B1 (ru) | 2002-04-19 | 2003-04-17 | Производные n-[фенил(пиперидин-2-ил)метил]бензамида и их применение в терапии |
Country Status (35)
| Country | Link |
|---|---|
| US (2) | US7326722B2 (https=) |
| EP (1) | EP1499589B1 (https=) |
| JP (1) | JP4597532B2 (https=) |
| KR (2) | KR20040103973A (https=) |
| CN (1) | CN100482646C (https=) |
| AR (1) | AR039413A1 (https=) |
| AT (1) | ATE361279T1 (https=) |
| AU (1) | AU2003262420B2 (https=) |
| BR (1) | BR0309397A (https=) |
| CA (1) | CA2481461C (https=) |
| CO (1) | CO5631432A2 (https=) |
| CY (1) | CY1108025T1 (https=) |
| DE (1) | DE60313602T2 (https=) |
| DK (1) | DK1499589T3 (https=) |
| EA (1) | EA007225B1 (https=) |
| EC (1) | ECSP045369A (https=) |
| ES (1) | ES2286444T3 (https=) |
| FR (1) | FR2838739B1 (https=) |
| HR (1) | HRP20040977B1 (https=) |
| IL (2) | IL164400A0 (https=) |
| IS (1) | IS2540B (https=) |
| MA (1) | MA27192A1 (https=) |
| ME (1) | MEP25608A (https=) |
| MX (1) | MXPA04010326A (https=) |
| NO (1) | NO329065B1 (https=) |
| NZ (1) | NZ536015A (https=) |
| PL (1) | PL373195A1 (https=) |
| PT (1) | PT1499589E (https=) |
| RS (1) | RS51888B (https=) |
| SI (1) | SI1499589T1 (https=) |
| TN (1) | TNSN04208A1 (https=) |
| TW (1) | TWI306402B (https=) |
| UA (1) | UA78025C2 (https=) |
| WO (1) | WO2003089411A1 (https=) |
| ZA (1) | ZA200408154B (https=) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2842804B1 (fr) | 2002-07-29 | 2004-09-03 | Sanofi Synthelabo | Derives de n-[phenyl(piperidin-2-yl)methyl]benzamide, leur preparation et leur application en therapeutique |
| FR2861073B1 (fr) * | 2003-10-17 | 2006-01-06 | Sanofi Synthelabo | Derives de n-[heteroaryl(piperidin-2-yl)methyl]benzamide, leur preparation et leur application en therapeutique |
| FR2861071B1 (fr) * | 2003-10-17 | 2006-01-06 | Sanofi Synthelabo | Derives de n-[phenyl(alkylpiperidin-2-yl) methyl]benzamide, leur prepartation et leur application en therapeutique |
| FR2861074B1 (fr) * | 2003-10-17 | 2006-04-07 | Sanofi Synthelabo | Derives de n-[phenyl(piperidin-2-yl)methyl]benzamide, leur preparation et leur application en therapeutique |
| FR2861070B1 (fr) * | 2003-10-17 | 2006-01-06 | Sanofi Synthelabo | Derives de n-[phenyl(pyrrolidin-2-yl)methyl]benzamide et n-[(azepan-2-yl)phenylmethyl]benzamide, leur preparation et leur application en therapeutique |
| WO2005044810A1 (en) * | 2003-10-30 | 2005-05-19 | Janssen Pharmaceutica, N.V. | Glyt2 modulators |
| US20050209317A1 (en) * | 2004-03-22 | 2005-09-22 | Apkarian A V | Method and compositions for treatment of chronic neuropathic pain |
| ES2520015T3 (es) * | 2005-04-08 | 2014-11-11 | Pfizer Products Inc. | [3.1.0]Heteroaril amidas bicíclicas como inhibidores de transporte de glicina de tipo 1 |
| JP2009179562A (ja) * | 2006-08-11 | 2009-08-13 | Taisho Pharmaceutical Co Ltd | グリシントランスポーター阻害剤 |
| FR2917735B1 (fr) * | 2007-06-21 | 2009-09-04 | Sanofi Aventis Sa | Nouveaux indazoles substitutes, leur preparation et leur utilisation en therapeutique |
| TW200911808A (en) * | 2007-07-23 | 2009-03-16 | Astrazeneca Ab | Novel compounds |
| MX2009014235A (es) | 2007-08-22 | 2010-04-27 | Abbott Gmbh & Co Kg | 4-bencilaminoquinolonas, composiciones farmaceuticas que las contiene y su uso. |
| MX2010010773A (es) | 2008-04-01 | 2011-04-11 | Abbott Gmbh & Co Kg | Tetrahidroisoquinolinas, composiciones farmaceuticas que las contienen y su uso en terapia. |
| WO2010087761A1 (en) * | 2009-01-28 | 2010-08-05 | Astrazeneca Ab | 2-aza-bicyclo[2.2.2]octane compounds and uses thereof |
| AR075442A1 (es) | 2009-02-16 | 2011-03-30 | Abbott Gmbh & Co Kg | Derivados de aminotetralina, composiciones farmaceuticas que las contienen y sus usos en terapia |
| TW201038569A (en) | 2009-02-16 | 2010-11-01 | Abbott Gmbh & Co Kg | Heterocyclic compounds, pharmaceutical compositions containing them, and their use in therapy |
| JP5618047B2 (ja) * | 2010-01-29 | 2014-11-05 | 国立大学法人千葉大学 | ポジトロン断層撮影法およびポジトロン放出化合物 |
| US8883839B2 (en) | 2010-08-13 | 2014-11-11 | Abbott Laboratories | Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy |
| US9051280B2 (en) | 2010-08-13 | 2015-06-09 | AbbVie Deutschland GmbH & Co. KG | Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy |
| US8877794B2 (en) | 2010-08-13 | 2014-11-04 | Abbott Laboratories | Phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy |
| US8846743B2 (en) | 2010-08-13 | 2014-09-30 | Abbott Laboratories | Aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy |
| US9045459B2 (en) | 2010-08-13 | 2015-06-02 | AbbVie Deutschland GmbH & Co. KG | Phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy |
| US9309200B2 (en) | 2011-05-12 | 2016-04-12 | AbbVie Deutschland GmbH & Co. KG | Benzazepine derivatives, pharmaceutical compositions containing them, and their use in therapy |
| EP2723718A1 (en) | 2011-06-24 | 2014-04-30 | Amgen Inc. | Trpm8 antagonists and their use in treatments |
| US8710043B2 (en) | 2011-06-24 | 2014-04-29 | Amgen Inc. | TRPM8 antagonists and their use in treatments |
| CA2844275A1 (en) | 2011-08-05 | 2013-02-14 | AbbVie Deutschland GmbH & Co. KG | Aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives, pharmaceutical compositions containing them, and their use in therapy |
| MX2014006004A (es) | 2011-11-18 | 2015-04-16 | Abbvie Deutschland | Derivados de aminobenzociclohepteno, aminotetralina, aminoindano y fenalcilamina n-sustituidas, composiciones farmaceuticas que los contienen, y su uso en terapia. |
| FR2983197B1 (fr) * | 2011-11-29 | 2014-07-25 | Assist Publ Hopitaux De Paris | Utilisation de phacetoperane pour traiter un trouble deficit de l'attention hyperactivite |
| US9365512B2 (en) | 2012-02-13 | 2016-06-14 | AbbVie Deutschland GmbH & Co. KG | Isoindoline derivatives, pharmaceutical compositions containing them, and their use in therapy |
| US8952009B2 (en) | 2012-08-06 | 2015-02-10 | Amgen Inc. | Chroman derivatives as TRPM8 inhibitors |
| US9656955B2 (en) | 2013-03-15 | 2017-05-23 | Abbvie Inc. | Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy |
| US9650334B2 (en) | 2013-03-15 | 2017-05-16 | Abbvie Inc. | Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy |
| CA2924689A1 (en) | 2013-10-17 | 2015-04-23 | AbbVie Deutschland GmbH & Co. KG | Aminochromane, aminothiochromane and amino-1,2,3,4-tetrahydroquinoline derivatives, pharmaceutical compositions containing them, and their use in therapy |
| MX2016004934A (es) | 2013-10-17 | 2016-12-20 | Abbvie Deutschland | Derivados de aminotetralina y aminoindano, composiciones farmaceuticas que los contienen, y su uso en terapia. |
| US9550754B2 (en) | 2014-09-11 | 2017-01-24 | AbbVie Deutschland GmbH & Co. KG | 4,5-dihydropyrazole derivatives, pharmaceutical compositions containing them, and their use in therapy |
| US20170143681A1 (en) | 2015-11-02 | 2017-05-25 | Apkarian Technologies Llc | Methods and compositions for treating pain |
| FR3045044B1 (fr) * | 2015-12-11 | 2019-04-19 | Liphatech | Composition et appat rodonticide comprenant du flocoumafene, procede de lutte contre des rongeurs cibles nuisibles |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5254569A (en) * | 1991-01-14 | 1993-10-19 | The Du Pont Merck Pharmaceutical Company | (Amidomethyl)nitrogen heterocyclic analgesics |
| JP3026845B2 (ja) * | 1991-02-20 | 2000-03-27 | 日清製粉株式会社 | ピペリジン誘導体 |
| US5524569A (en) * | 1995-03-20 | 1996-06-11 | Rich; William A. | Anchor cover |
| EP1058684A1 (en) * | 1998-03-06 | 2000-12-13 | Janssen Pharmaceutica N.V. | Glycine transport inhibitors |
| AU2001254546A1 (en) * | 2000-04-20 | 2001-11-07 | Nps Allelix Corp. | Aminopiperidines |
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2002
- 2002-04-19 FR FR0204916A patent/FR2838739B1/fr not_active Expired - Fee Related
-
2003
- 2003-04-15 AR ARP030101310A patent/AR039413A1/es unknown
- 2003-04-17 ME MEP-256/08A patent/MEP25608A/xx unknown
- 2003-04-17 DE DE60313602T patent/DE60313602T2/de not_active Expired - Lifetime
- 2003-04-17 RS YU91404A patent/RS51888B/sr unknown
- 2003-04-17 CA CA002481461A patent/CA2481461C/en not_active Expired - Fee Related
- 2003-04-17 PL PL03373195A patent/PL373195A1/xx not_active IP Right Cessation
- 2003-04-17 UA UA20041008110A patent/UA78025C2/uk unknown
- 2003-04-17 BR BR0309397-2A patent/BR0309397A/pt not_active IP Right Cessation
- 2003-04-17 JP JP2003586132A patent/JP4597532B2/ja not_active Expired - Fee Related
- 2003-04-17 ES ES03740634T patent/ES2286444T3/es not_active Expired - Lifetime
- 2003-04-17 AU AU2003262420A patent/AU2003262420B2/en not_active Ceased
- 2003-04-17 MX MXPA04010326A patent/MXPA04010326A/es active IP Right Grant
- 2003-04-17 KR KR10-2004-7016718A patent/KR20040103973A/ko not_active Ceased
- 2003-04-17 KR KR1020087018794A patent/KR101019313B1/ko not_active Expired - Fee Related
- 2003-04-17 US US10/511,886 patent/US7326722B2/en not_active Expired - Fee Related
- 2003-04-17 PT PT03740634T patent/PT1499589E/pt unknown
- 2003-04-17 SI SI200330893T patent/SI1499589T1/sl unknown
- 2003-04-17 IL IL16440003A patent/IL164400A0/xx unknown
- 2003-04-17 AT AT03740634T patent/ATE361279T1/de active
- 2003-04-17 EA EA200401172A patent/EA007225B1/ru not_active IP Right Cessation
- 2003-04-17 WO PCT/FR2003/001232 patent/WO2003089411A1/fr not_active Ceased
- 2003-04-17 DK DK03740634T patent/DK1499589T3/da active
- 2003-04-17 EP EP03740634A patent/EP1499589B1/fr not_active Expired - Lifetime
- 2003-04-17 CN CNB038140063A patent/CN100482646C/zh not_active Expired - Fee Related
- 2003-04-17 HR HR20040977A patent/HRP20040977B1/xx not_active IP Right Cessation
- 2003-04-17 NZ NZ536015A patent/NZ536015A/en not_active IP Right Cessation
- 2003-04-18 TW TW092109074A patent/TWI306402B/zh not_active IP Right Cessation
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2004
- 2004-09-30 IS IS7479A patent/IS2540B/is unknown
- 2004-10-04 IL IL164400A patent/IL164400A/en not_active IP Right Cessation
- 2004-10-07 MA MA27892A patent/MA27192A1/fr unknown
- 2004-10-08 ZA ZA200408154A patent/ZA200408154B/en unknown
- 2004-10-14 CO CO04103284A patent/CO5631432A2/es not_active Application Discontinuation
- 2004-10-15 NO NO20044388A patent/NO329065B1/no not_active IP Right Cessation
- 2004-10-18 TN TNP2004000208A patent/TNSN04208A1/fr unknown
- 2004-10-18 EC EC2004005369A patent/ECSP045369A/es unknown
-
2007
- 2007-04-03 US US11/695,912 patent/US20070197601A1/en not_active Abandoned
- 2007-07-24 CY CY20071100988T patent/CY1108025T1/el unknown
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| MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KZ KG MD TJ TM RU |