FR2861074B1 - Derives de n-[phenyl(piperidin-2-yl)methyl]benzamide, leur preparation et leur application en therapeutique - Google Patents
Derives de n-[phenyl(piperidin-2-yl)methyl]benzamide, leur preparation et leur application en therapeutiqueInfo
- Publication number
- FR2861074B1 FR2861074B1 FR0312140A FR0312140A FR2861074B1 FR 2861074 B1 FR2861074 B1 FR 2861074B1 FR 0312140 A FR0312140 A FR 0312140A FR 0312140 A FR0312140 A FR 0312140A FR 2861074 B1 FR2861074 B1 FR 2861074B1
- Authority
- FR
- France
- Prior art keywords
- piperidin
- phenyl
- methyl
- preparation
- therapeutic use
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Priority Applications (19)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0312140A FR2861074B1 (fr) | 2003-10-17 | 2003-10-17 | Derives de n-[phenyl(piperidin-2-yl)methyl]benzamide, leur preparation et leur application en therapeutique |
MEP-125/08A MEP12508A (en) | 2003-10-17 | 2004-10-15 | Derivatives of n-/phenyl(piperidine-2-yl) methyl benzamide, preparation method thereof and applications of same in therapeutics |
CNA2004800338506A CN1882540A (zh) | 2003-10-17 | 2004-10-15 | N-[苯基(哌啶-2-基)甲基]苯甲酰胺衍生物、其制备以及其治疗用途 |
BRPI0415504-1A BRPI0415504A (pt) | 2003-10-17 | 2004-10-15 | derivados de n-fenil(piperidin-2-il)metil benzamida, seu preparo e sua aplicação em terapêutica |
KR1020067007382A KR20060094079A (ko) | 2003-10-17 | 2004-10-15 | N-[페닐(피페리딘-2-일)메틸]벤즈아미드의 유도체, 그의제조 방법 및 치료법에서의 그의 용도 |
RU2006116885/04A RU2351588C2 (ru) | 2003-10-17 | 2004-10-15 | Производные n-фенил(пиперидин-2-ил)метил-бензамида и их применение в терапии |
PCT/FR2004/002640 WO2005037792A1 (fr) | 2003-10-17 | 2004-10-15 | Derives de n-``phenyl(piperidin-2-yl)methyl !benzamide, leur preparation et leur application en therapeutique |
AU2004281214A AU2004281214B2 (en) | 2003-10-17 | 2004-10-15 | Derivatives of N-``phenyl(piperidine-2-yl) methyl benzamide, preparation method thereof and applications of same in therapeutics |
NZ547164A NZ547164A (en) | 2003-10-17 | 2004-10-15 | Derivatives of n-[phenyl(piperidine-2-yl)methyl]benzamide, preparation and therapeutic use thereof |
JP2006534797A JP2007508358A (ja) | 2003-10-17 | 2004-10-15 | N−[フェニル(ピペリジン−2−イル)メチル]ベンズアミド誘導体、この調製方法およびこの治療法における使用 |
EP04791551A EP1680402A1 (fr) | 2003-10-17 | 2004-10-15 | Derives de n-[[phenyl(piperidin-2-yl)methyl]benzamide, leur preparation et leur application en therapeutique |
CA002542373A CA2542373A1 (fr) | 2003-10-17 | 2004-10-15 | Derives de n-[phenyl(piperidin-2-yl)methyl] benzamide, leur preparation et leur application en therapeutique |
YUP-2006/0318A RS20060318A (en) | 2003-10-17 | 2004-10-15 | Derivatives of n-/phenyl(piperidine-2-yl)methyl/benzamide, preparation method thereof and application of same in therapeutics |
IL174942A IL174942A (en) | 2003-10-17 | 2006-04-11 | Derivatives of n-[phenyl(piperidine-2-yl)methyl]arylamides, pharmaceutical compositions comprising them and their use in the preparation of medicaments |
MA28946A MA28101A1 (fr) | 2003-10-17 | 2006-04-17 | Derives de n-'' phenyl ( piperidin-2-yl) methyl ! benzamide, leur preparation et leur application en therapeutique |
US11/405,169 US7750025B2 (en) | 2003-10-17 | 2006-04-17 | Derivatives of N-phenyl (piperidine-2-yl) methyl benzamide, preparation method thereof and applications of same in therapeutics |
NO20062105A NO20062105L (no) | 2003-10-17 | 2006-05-10 | Derivater av N-"fenyl(piperidin-2-yl) metylbenzamid, fremgangsmate for fremstilling derav og anvendelse av forbindelsene innenfor terapi |
ZA200603937A ZA200603937B (en) | 2003-10-17 | 2006-05-16 | Derivatives of N-phenyl (piperidine-2-yl) methyl benzamide, preparation method thereof and applications of same in therapeutics |
US12/784,007 US20100234424A1 (en) | 2003-10-17 | 2010-05-20 | Derivatives of n-phenyl(piperidine-2-yl) methyl benzamide preparation method thereof and applications of same in therapeutics |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0312140A FR2861074B1 (fr) | 2003-10-17 | 2003-10-17 | Derives de n-[phenyl(piperidin-2-yl)methyl]benzamide, leur preparation et leur application en therapeutique |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2861074A1 FR2861074A1 (fr) | 2005-04-22 |
FR2861074B1 true FR2861074B1 (fr) | 2006-04-07 |
Family
ID=34385233
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR0312140A Expired - Fee Related FR2861074B1 (fr) | 2003-10-17 | 2003-10-17 | Derives de n-[phenyl(piperidin-2-yl)methyl]benzamide, leur preparation et leur application en therapeutique |
Country Status (18)
Country | Link |
---|---|
US (2) | US7750025B2 (fr) |
EP (1) | EP1680402A1 (fr) |
JP (1) | JP2007508358A (fr) |
KR (1) | KR20060094079A (fr) |
CN (1) | CN1882540A (fr) |
AU (1) | AU2004281214B2 (fr) |
BR (1) | BRPI0415504A (fr) |
CA (1) | CA2542373A1 (fr) |
FR (1) | FR2861074B1 (fr) |
IL (1) | IL174942A (fr) |
MA (1) | MA28101A1 (fr) |
ME (1) | MEP12508A (fr) |
NO (1) | NO20062105L (fr) |
NZ (1) | NZ547164A (fr) |
RS (1) | RS20060318A (fr) |
RU (1) | RU2351588C2 (fr) |
WO (1) | WO2005037792A1 (fr) |
ZA (1) | ZA200603937B (fr) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2842804B1 (fr) | 2002-07-29 | 2004-09-03 | Sanofi Synthelabo | Derives de n-[phenyl(piperidin-2-yl)methyl]benzamide, leur preparation et leur application en therapeutique |
GB0600427D0 (en) * | 2006-01-10 | 2006-02-15 | Glaxo Group Ltd | Compounds |
AU2008226947B2 (en) | 2007-03-08 | 2014-07-17 | The Board Of Trustees Of The Leland Stanford Junior University | Mitochondrial aldehyde dehydrogenase-2 modulators and methods of use thereof |
FR2917735B1 (fr) * | 2007-06-21 | 2009-09-04 | Sanofi Aventis Sa | Nouveaux indazoles substitutes, leur preparation et leur utilisation en therapeutique |
TW200911808A (en) * | 2007-07-23 | 2009-03-16 | Astrazeneca Ab | Novel compounds |
JP5619609B2 (ja) | 2007-08-22 | 2014-11-05 | アボット ゲーエムベーハーウント カンパニー カーゲー | 4−ベンジルアミノキノリン類、これらを含む医薬組成物およびこれらの使用 |
WO2009121872A2 (fr) | 2008-04-01 | 2009-10-08 | Abbott Gmbh & Co. Kg | Tétrahydroisoquinoléines, compositions pharmaceutiques les contenant et leur utilisation en thérapie |
JP2012502048A (ja) | 2008-09-08 | 2012-01-26 | ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティ | アルデヒドデヒドロゲナーゼ活性のモジュレーターおよびその使用方法 |
US8389522B2 (en) * | 2008-10-28 | 2013-03-05 | The Board Of Trustees Of The Leland Stanford Junior University | Modulators of aldehyde dehydrogenase and methods of use thereof |
PE20120500A1 (es) * | 2009-01-27 | 2012-05-04 | Hoffmann La Roche | Piperidinas sustituidas con heteroilamino y aroilamino como inhibidores de glyt-1 |
AR075182A1 (es) * | 2009-01-28 | 2011-03-16 | Astrazeneca Ab | Compuestos 2-aza-biciclo (2.2.2) octano y sus usos |
TW201038569A (en) | 2009-02-16 | 2010-11-01 | Abbott Gmbh & Co Kg | Heterocyclic compounds, pharmaceutical compositions containing them, and their use in therapy |
AR075442A1 (es) | 2009-02-16 | 2011-03-30 | Abbott Gmbh & Co Kg | Derivados de aminotetralina, composiciones farmaceuticas que las contienen y sus usos en terapia |
FR2943056A1 (fr) * | 2009-03-16 | 2010-09-17 | Sanofi Aventis | Derives de n-°2-aza-bicyclo°2.1.1!hex-1-yl)-aryl-methyl!- heterobenzamide, leur preparation et leur application en therapeutique |
FR2944283B1 (fr) * | 2009-04-14 | 2011-05-06 | Sanofi Aventis | Derives de n-°(2-aza-bicyclo°2.1.1!hex-1-yl)-aryl-methyl!- heterobenzamide, leur preparation et leur application en therapeutique |
CN102356074A (zh) * | 2009-03-16 | 2012-02-15 | 赛诺菲 | N-[(2-氮杂-二环[2.1.1]己-1-基)-芳基-)甲基]-杂苯甲酰胺的衍生物,它们的制备和它们在治疗中的应用 |
JP5618047B2 (ja) * | 2010-01-29 | 2014-11-05 | 国立大学法人千葉大学 | ポジトロン断層撮影法およびポジトロン放出化合物 |
US9045459B2 (en) | 2010-08-13 | 2015-06-02 | AbbVie Deutschland GmbH & Co. KG | Phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy |
US9051280B2 (en) | 2010-08-13 | 2015-06-09 | AbbVie Deutschland GmbH & Co. KG | Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy |
US8877794B2 (en) | 2010-08-13 | 2014-11-04 | Abbott Laboratories | Phenalkylamine derivatives, pharmaceutical compositions containing them, and their use in therapy |
US8883839B2 (en) | 2010-08-13 | 2014-11-11 | Abbott Laboratories | Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy |
US8846743B2 (en) | 2010-08-13 | 2014-09-30 | Abbott Laboratories | Aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy |
WO2012149106A1 (fr) | 2011-04-29 | 2012-11-01 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions et procédés d'augmentation de la prolifération de cellules souches salivaires adultes |
US9309200B2 (en) | 2011-05-12 | 2016-04-12 | AbbVie Deutschland GmbH & Co. KG | Benzazepine derivatives, pharmaceutical compositions containing them, and their use in therapy |
JP2014521682A (ja) | 2011-08-05 | 2014-08-28 | アッヴィ・ドイチュラント・ゲー・エム・ベー・ハー・ウント・コー・カー・ゲー | アミノクロマン、アミノチオクロマンおよびアミノ−1,2,3,4−テトラヒドロキノリン誘導体、これらを含有する医薬組成物、ならびに治療におけるこれらの使用 |
WO2013072520A1 (fr) | 2011-11-18 | 2013-05-23 | AbbVie Deutschland GmbH & Co. KG | Dérivés aminobenzocycloheptène, aminotétraline, aminoindane et phénalkylamine n-substitués, composition pharmaceutiques les contenant, et leur application thérapeutique |
FR2983197B1 (fr) * | 2011-11-29 | 2014-07-25 | Assist Publ Hopitaux De Paris | Utilisation de phacetoperane pour traiter un trouble deficit de l'attention hyperactivite |
US9365512B2 (en) | 2012-02-13 | 2016-06-14 | AbbVie Deutschland GmbH & Co. KG | Isoindoline derivatives, pharmaceutical compositions containing them, and their use in therapy |
CN105358531B (zh) | 2013-03-14 | 2017-11-14 | 利兰-斯坦福大学初级学院的董事会 | 线粒体醛脱氢酶‑2调节剂和其使用方法 |
US9656955B2 (en) | 2013-03-15 | 2017-05-23 | Abbvie Inc. | Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy |
US9650334B2 (en) | 2013-03-15 | 2017-05-16 | Abbvie Inc. | Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy |
WO2015055771A1 (fr) | 2013-10-17 | 2015-04-23 | AbbVie Deutschland GmbH & Co. KG | Dérivés d'aminotétraline et d'aminoindane, compositions pharmaceutiques les contenant et leur utilisation en thérapie |
EP3057960B1 (fr) | 2013-10-17 | 2019-02-27 | AbbVie Deutschland GmbH & Co. KG | Dérivés d'aminochromane, d'aminothiochromane et d'amino-1,2,3,4-tétrahydroquinoléine, compositions pharmaceutiques contenant ceux-ci et leur utilisation thérapeutique |
US9550754B2 (en) | 2014-09-11 | 2017-01-24 | AbbVie Deutschland GmbH & Co. KG | 4,5-dihydropyrazole derivatives, pharmaceutical compositions containing them, and their use in therapy |
RU2680526C1 (ru) * | 2016-07-05 | 2019-02-22 | Федеральное государственное бюджетное научное учреждение "Томский национальный исследовательский медицинский центр Российской академии наук" (Томский НИМЦ) | Нейропротекторное средство, обладающее свойствами антиоксиданта и донатора оксида азота |
WO2018232264A1 (fr) * | 2017-06-15 | 2018-12-20 | The Board Of Regents Of The University Of Oklahoma | Dérivés de benzamide permettant d'inhiber le stress du réticulum endoplasmique (er) |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
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US2928835A (en) * | 1959-02-19 | 1960-03-15 | Rhone Poulenc Sa | New esters |
US3336300A (en) * | 1965-04-13 | 1967-08-15 | American Home Prod | 1, 2, 3, 4-tetrahydro-5h-benzodiazepin-5-ones |
JPH02262562A (ja) | 1988-10-20 | 1990-10-25 | Ishihara Sangyo Kaisha Ltd | イミダゾール系化合物 |
JP2765876B2 (ja) | 1988-10-24 | 1998-06-18 | 科研製薬株式会社 | ピリジルケトオキシムエーテル誘導体 |
US5254569A (en) * | 1991-01-14 | 1993-10-19 | The Du Pont Merck Pharmaceutical Company | (Amidomethyl)nitrogen heterocyclic analgesics |
JP3026845B2 (ja) * | 1991-02-20 | 2000-03-27 | 日清製粉株式会社 | ピペリジン誘導体 |
FR2838739B1 (fr) * | 2002-04-19 | 2004-05-28 | Sanofi Synthelabo | Derives de n-[phenyl(piperidin-2-yl)methyl)benzamide, leur preparation et leur application en therapeutique |
FR2842804B1 (fr) * | 2002-07-29 | 2004-09-03 | Sanofi Synthelabo | Derives de n-[phenyl(piperidin-2-yl)methyl]benzamide, leur preparation et leur application en therapeutique |
FR2861073B1 (fr) * | 2003-10-17 | 2006-01-06 | Sanofi Synthelabo | Derives de n-[heteroaryl(piperidin-2-yl)methyl]benzamide, leur preparation et leur application en therapeutique |
FR2861076B1 (fr) * | 2003-10-17 | 2006-01-06 | Sanofi Synthelabo | Derives de n-heterocyclymethylbenzamide, leur preparation et leur application en therapeutique |
FR2861071B1 (fr) * | 2003-10-17 | 2006-01-06 | Sanofi Synthelabo | Derives de n-[phenyl(alkylpiperidin-2-yl) methyl]benzamide, leur prepartation et leur application en therapeutique |
FR2861070B1 (fr) * | 2003-10-17 | 2006-01-06 | Sanofi Synthelabo | Derives de n-[phenyl(pyrrolidin-2-yl)methyl]benzamide et n-[(azepan-2-yl)phenylmethyl]benzamide, leur preparation et leur application en therapeutique |
FR2906251B1 (fr) * | 2006-09-22 | 2008-11-07 | Sanofi Aventis Sa | Derives de pyrrolizine, indolizine et quinolizine, leur preparation et leur application en therapeutique |
-
2003
- 2003-10-17 FR FR0312140A patent/FR2861074B1/fr not_active Expired - Fee Related
-
2004
- 2004-10-15 BR BRPI0415504-1A patent/BRPI0415504A/pt not_active IP Right Cessation
- 2004-10-15 KR KR1020067007382A patent/KR20060094079A/ko not_active Application Discontinuation
- 2004-10-15 AU AU2004281214A patent/AU2004281214B2/en not_active Ceased
- 2004-10-15 EP EP04791551A patent/EP1680402A1/fr not_active Withdrawn
- 2004-10-15 JP JP2006534797A patent/JP2007508358A/ja active Pending
- 2004-10-15 RS YUP-2006/0318A patent/RS20060318A/sr unknown
- 2004-10-15 RU RU2006116885/04A patent/RU2351588C2/ru not_active IP Right Cessation
- 2004-10-15 NZ NZ547164A patent/NZ547164A/en not_active IP Right Cessation
- 2004-10-15 WO PCT/FR2004/002640 patent/WO2005037792A1/fr active Application Filing
- 2004-10-15 ME MEP-125/08A patent/MEP12508A/xx unknown
- 2004-10-15 CA CA002542373A patent/CA2542373A1/fr not_active Abandoned
- 2004-10-15 CN CNA2004800338506A patent/CN1882540A/zh active Pending
-
2006
- 2006-04-11 IL IL174942A patent/IL174942A/en not_active IP Right Cessation
- 2006-04-17 US US11/405,169 patent/US7750025B2/en not_active Expired - Fee Related
- 2006-04-17 MA MA28946A patent/MA28101A1/fr unknown
- 2006-05-10 NO NO20062105A patent/NO20062105L/no not_active Application Discontinuation
- 2006-05-16 ZA ZA200603937A patent/ZA200603937B/xx unknown
-
2010
- 2010-05-20 US US12/784,007 patent/US20100234424A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
FR2861074A1 (fr) | 2005-04-22 |
EP1680402A1 (fr) | 2006-07-19 |
CN1882540A (zh) | 2006-12-20 |
MA28101A1 (fr) | 2006-08-01 |
RS20060318A (en) | 2008-11-28 |
US20060223885A1 (en) | 2006-10-05 |
JP2007508358A (ja) | 2007-04-05 |
CA2542373A1 (fr) | 2005-04-28 |
BRPI0415504A (pt) | 2006-12-12 |
AU2004281214B2 (en) | 2010-07-08 |
WO2005037792A1 (fr) | 2005-04-28 |
ZA200603937B (en) | 2009-01-28 |
KR20060094079A (ko) | 2006-08-28 |
RU2006116885A (ru) | 2007-11-27 |
US7750025B2 (en) | 2010-07-06 |
RU2351588C2 (ru) | 2009-04-10 |
IL174942A (en) | 2011-03-31 |
MEP12508A (en) | 2010-06-10 |
NO20062105L (no) | 2006-05-10 |
AU2004281214A1 (en) | 2005-04-28 |
IL174942A0 (en) | 2006-08-20 |
NZ547164A (en) | 2009-11-27 |
US20100234424A1 (en) | 2010-09-16 |
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