DZ3196A1 - Dérivés d'acide indolyl-3-glyoxyle à bonnes proprietes thérapeutiques. - Google Patents

Dérivés d'acide indolyl-3-glyoxyle à bonnes proprietes thérapeutiques.

Info

Publication number
DZ3196A1
DZ3196A1 DZ003196A DZ003196A DZ3196A1 DZ 3196 A1 DZ3196 A1 DZ 3196A1 DZ 003196 A DZ003196 A DZ 003196A DZ 003196 A DZ003196 A DZ 003196A DZ 3196 A1 DZ3196 A1 DZ 3196A1
Authority
DZ
Algeria
Prior art keywords
indolyl
acid derivatives
therapeutic properties
good therapeutic
glyoxyl acid
Prior art date
Application number
DZ003196A
Other languages
English (en)
French (fr)
Inventor
Bernd Nickel
Thomas Klenner
Gerald Bacher
Thomas Beckers
Peter Emig
Juergen Engel
Erik Bruyneel
Guenter Kamp
Kirsten Peters
Original Assignee
Baxter Healthcare Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19946301A external-priority patent/DE19946301A1/de
Application filed by Baxter Healthcare Sa filed Critical Baxter Healthcare Sa
Application granted granted Critical
Publication of DZ3196A1 publication Critical patent/DZ3196A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
DZ003196A 1999-09-28 2000-09-26 Dérivés d'acide indolyl-3-glyoxyle à bonnes proprietes thérapeutiques. DZ3196A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19946301A DE19946301A1 (de) 1998-04-02 1999-09-28 Indolyl-3-glyoxylsäure-Derivate mit therapeutisch wertvollen Eigenschaften

Publications (1)

Publication Number Publication Date
DZ3196A1 true DZ3196A1 (fr) 2001-04-05

Family

ID=7923485

Family Applications (1)

Application Number Title Priority Date Filing Date
DZ003196A DZ3196A1 (fr) 1999-09-28 2000-09-26 Dérivés d'acide indolyl-3-glyoxyle à bonnes proprietes thérapeutiques.

Country Status (32)

Country Link
EP (1) EP1218006B1 (cs)
JP (1) JP2003510274A (cs)
KR (1) KR100759242B1 (cs)
CN (1) CN1301712C (cs)
AR (1) AR025885A1 (cs)
AT (1) ATE459356T1 (cs)
AU (1) AU783436B2 (cs)
BG (1) BG106639A (cs)
BR (1) BR0014378A (cs)
CA (1) CA2386069C (cs)
CZ (1) CZ303246B6 (cs)
DE (1) DE50015879D1 (cs)
DZ (1) DZ3196A1 (cs)
EE (1) EE200200169A (cs)
ES (1) ES2342042T3 (cs)
GE (1) GEP20043250B (cs)
HK (1) HK1048941B (cs)
HR (1) HRP20020369A2 (cs)
HU (1) HUP0202788A3 (cs)
IL (2) IL148670A0 (cs)
IS (1) IS6319A (cs)
MX (1) MXPA02002824A (cs)
NO (1) NO322614B1 (cs)
NZ (1) NZ517988A (cs)
PL (1) PL199576B1 (cs)
RS (1) RS51302B (cs)
RU (1) RU2282444C2 (cs)
SK (1) SK287533B6 (cs)
TW (1) TWI269654B (cs)
UA (1) UA75872C2 (cs)
WO (1) WO2001022954A2 (cs)
ZA (1) ZA200202556B (cs)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19962300A1 (de) * 1999-12-23 2001-06-28 Asta Medica Ag Substituierte N-Benzyl-Indol-3-yl-glyoxylsäure-Derivate mit Antitumorwirkung
WO2001092224A1 (en) 2000-05-31 2001-12-06 Astrazeneca Ab Indole derivatives with vascular damaging activity
DE10037310A1 (de) 2000-07-28 2002-02-07 Asta Medica Ag Neue Indolderivate und deren Verwendung als Arzneimittel
MXPA05013121A (es) * 2003-06-05 2006-03-17 Zentaris Gmbh Derivados de indol con efecto de induccion de apoptosis.
EP1484329A1 (de) * 2003-06-06 2004-12-08 Zentaris GmbH Indolderivate mit Apoptose induzierender Wirkung
EP1595878A1 (de) * 2004-05-15 2005-11-16 Zentaris GmbH Indolderivate mit Apoptose induzierender Wirkung
US20050124623A1 (en) 2003-11-26 2005-06-09 Bender John A. Diazaindole-dicarbonyl-piperazinyl antiviral agents
CA2567813C (en) * 2004-05-23 2015-11-24 Gerard M. Housey Theramutein modulators
EP1809279B1 (en) * 2004-11-08 2013-05-29 Baxter International Inc. Particulate compositions of tubulin inhibitor
US20060100432A1 (en) 2004-11-09 2006-05-11 Matiskella John D Crystalline materials of 1-(4-benzoyl-piperazin-1-yl)-2-[4-methoxy-7-(3-methyl-[1,2,4]triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-ethane-1,2-dione
US8604055B2 (en) 2004-12-31 2013-12-10 Dr. Reddy's Laboratories Ltd. Substituted benzylamino quinolines as cholesterol ester-transfer protein inhibitors
US9040558B2 (en) 2004-12-31 2015-05-26 Dr. Reddy's Laboratories Ltd. Substituted benzylamino quinolines as cholesterol ester-transfer protein inhibitors
US7851476B2 (en) 2005-12-14 2010-12-14 Bristol-Myers Squibb Company Crystalline forms of 1-benzoyl-4-[2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-YL)-1-[(phosphonooxy)methyl]-1H-pyrrolo[2,3-C]pyridin-3-YL]-1,2-dioxoethyl]-piperazine
US7807671B2 (en) 2006-04-25 2010-10-05 Bristol-Myers Squibb Company Diketo-piperazine and piperidine derivatives as antiviral agents
CA2670778A1 (en) * 2006-11-28 2008-06-05 Ziopharm Oncology, Inc. Use of indolyl-3-glyoxylic acid derivatives including indibulin, alone or in combination with further agents for treating cancer
WO2013024358A2 (en) 2011-08-18 2013-02-21 Dr. Reddy's Laboratories Ltd. Substituted heterocyclic amine compounds as cholestryl ester-transfer protein (cetp) inhibitors
KR101803866B1 (ko) 2011-09-27 2017-12-04 닥터 레디스 레보러터리즈 리미티드 동맥경화증 치료에 유용한 콜레스테릴 에스테르-전달 단백질(cetp) 억제제로서 5-벤질아미노메틸-6-아미노피라졸로[3,4-b]피리딘 유도체
WO2014089177A2 (en) 2012-12-04 2014-06-12 Massachusetts Institute Of Technology Compounds, conjugates and compositions of epipolythiodiketopiperazines and polythiodiketopiperazines
US10201623B2 (en) 2013-03-15 2019-02-12 Memorial Sloan Kettering Cancer Center HSP90-targeted cardiac imaging and therapy
WO2017197045A1 (en) 2016-05-11 2017-11-16 Movassaghi Mohammad Convergent and enantioselective total synthesis of communesin analogs
WO2018209239A1 (en) 2017-05-11 2018-11-15 Massachusetts Institute Of Technology Potent agelastatin derivatives as modulators for cancer invasion and metastasis
CN109111501B (zh) * 2017-06-23 2022-04-22 首都医科大学 脂肪氨基酸修饰的吲哚乙醇衍生物, 其合成，活性和应用
US10640508B2 (en) 2017-10-13 2020-05-05 Massachusetts Institute Of Technology Diazene directed modular synthesis of compounds with quaternary carbon centers
US11535634B2 (en) 2019-06-05 2022-12-27 Massachusetts Institute Of Technology Compounds, conjugates, and compositions of epipolythiodiketopiperazines and polythiodiketopiperazines and uses thereof
WO2022182415A1 (en) 2021-02-24 2022-09-01 Massachusetts Institute Of Technology Himastatin derivatives, and processes of preparation thereof, and uses thereof

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4128089A (en) 1988-09-15 1990-03-22 Rorer International (Overseas) Inc. Monoclonal antibodies specific to human epidermal growth factor receptor and therapeutic methods employing same
RU2047603C1 (ru) * 1991-12-09 1995-11-10 Матвей Абрамович Рехтер 1-алкил-2-ацилиндолы и способы их получения
NZ314207A (en) * 1992-09-28 2000-12-22 Vertex Pharma 1-(2-Oxoacetyl)-piperidine-2-carboxylic acid derivatives as multi drug resistant cancer cell sensitizers
EP0617961A4 (en) * 1992-10-20 1995-03-29 Toray Industries INHIBITOR OF EOSINOPHILIN INFILTRATION.
DE19636150A1 (de) * 1996-09-06 1998-03-12 Asta Medica Ag N-substituierte Indol-3-glyoxylamide mit antiasthmatischer, antiallergischer und immunsuppressiver/immunmodulierender Wirkung
CA2286038A1 (en) 1997-04-08 1998-10-15 Banyu Pharmaceutical Co., Ltd. Cancerous metastasis-associated gene
EA003876B1 (ru) * 1998-02-25 2003-10-30 Дженетикс Инститьют, Ллс Ингибиторы фосфолипазных ферментов
HUP0102612A2 (hu) * 1998-03-12 2001-11-28 Novo Nordisk A/S Fehérje-tirozinfoszfatázokat moduláló vegyületek és ezeket tartalmazó gyógyászati készítmények
DE19814838C2 (de) * 1998-04-02 2001-01-18 Asta Medica Ag Indolyl-3-glyoxylsäure-Derivate mit Antitumorwirkung
UA59443C2 (uk) * 1998-04-28 2003-09-15 Арцнайміттельверк Дрезден Гмбх Гідроксііндол, спосіб його одержання, лікарська форма на його основі та спосіб її одержання
JP2000239252A (ja) * 1999-02-16 2000-09-05 Mitsubishi Chemicals Corp インドール誘導体
AU4834200A (en) * 1999-05-10 2000-11-21 Protarga, Inc. Fatty acid-n-substituted indol-3-glyoxyl-amide compositions and uses thereof

Also Published As

Publication number Publication date
BG106639A (bg) 2002-12-29
ATE459356T1 (de) 2010-03-15
HUP0202788A3 (en) 2003-02-28
WO2001022954A3 (de) 2002-03-28
CZ303246B6 (cs) 2012-06-20
YU22702A (sh) 2004-12-31
EP1218006A2 (de) 2002-07-03
SK4072002A3 (en) 2003-11-04
NO20021367L (no) 2002-05-22
PL199576B1 (pl) 2008-10-31
EE200200169A (et) 2003-04-15
NO322614B1 (no) 2006-11-06
CN1301712C (zh) 2007-02-28
IS6319A (is) 2002-03-21
KR20030019295A (ko) 2003-03-06
AU783436B2 (en) 2005-10-27
DE50015879D1 (de) 2010-04-15
HK1048941A1 (en) 2003-04-25
UA75872C2 (en) 2006-06-15
EP1218006B1 (de) 2010-03-03
AU7782900A (en) 2001-04-30
ES2342042T3 (es) 2010-07-01
MXPA02002824A (es) 2003-07-21
PL364811A1 (en) 2004-12-13
GEP20043250B (en) 2004-06-25
KR100759242B1 (ko) 2007-09-18
HRP20020369A2 (en) 2004-12-31
RS51302B (sr) 2010-12-31
RU2282444C2 (ru) 2006-08-27
IL148670A0 (en) 2002-09-12
WO2001022954A2 (de) 2001-04-05
HK1048941B (zh) 2007-09-21
JP2003510274A (ja) 2003-03-18
ZA200202556B (en) 2003-08-27
TWI269654B (en) 2007-01-01
SK287533B6 (sk) 2011-01-04
IL148670A (en) 2009-09-01
CN1376064A (zh) 2002-10-23
HUP0202788A2 (hu) 2003-01-28
AR025885A1 (es) 2002-12-18
CA2386069C (en) 2012-08-14
CA2386069A1 (en) 2001-04-05
CZ20021005A3 (cs) 2004-01-14
NZ517988A (en) 2004-10-29
NO20021367D0 (no) 2002-03-19
BR0014378A (pt) 2003-07-29

Similar Documents

Publication Publication Date Title
DZ3196A1 (fr) Dérivés d'acide indolyl-3-glyoxyle à bonnes proprietes thérapeutiques.
DZ2439A1 (fr) Dérivés d'acide hexanoïque nouveaux.
ATE299134T1 (de) Neuartige aminodicarbonsäurederivate mit pharmazeutischen eigenschaften
DZ2800A1 (fr) Nouveau dérivé de l'acide 3-aryl-2-hydroxypropionique.
MA26746A1 (fr) Conjugues d'erythropoietine
MA27041A1 (fr) Derives d'acide dicarboxylique aromatique
DZ2799A1 (fr) Nouveaux dérivés de l'acide 3-aryl propionique et analogues.
BRPI9909282B1 (pt) compostos de Éter aminociclohexÍlicos e usos dos mesmos.
EP1295865A4 (en) NEW DICARBOXYLENE DERIVATIVES
MA26848A1 (fr) Derives d'heterocyclo-alkylsufonylpyrazole nouveaux servant d'agents anti-inflammatoires/analgesiques.
FR2792273B1 (fr) Desaeration d'une direction assistee
ITRM940561A0 (it) Catetere di drenaggio per neo-vesciche urinarie contenenti realizzate con l'uso dell'intestino o dello stomaco
DE60020494D1 (de) Injektionskatheter
EP1153612A4 (en) Anticancer agent potentiators
FR2796829B1 (fr) Plaque d'osteotomie tibiale
ITTO950554A0 (it) Diamidi aromatiche acide ad attivita' antigastrinica, procedimento perla loro preparazione e loro uso farmaceutico
FR2794763B1 (fr) Nouveaux derives de l'acide hyaluronique, leur preparation et leur utilisation
UA3396S (uk) Куртка дитяча
UA3259S (uk) Тестер медичний "глюкофот-2"
ES1042364Y (es) "pañal perfeccionado".
UA3495S (uk) Печиво "аладін"
UA3553S (uk) Цитрусова карамель "рокс"
ES1042694Y (es) "expositor perfeccionado".
UA2995S (uk) Тренажер "тяга зверху"
UA3711S (uk) Сувенір "святиня"