ITTO950554A0 - Diamidi aromatiche acide ad attivita' antigastrinica, procedimento perla loro preparazione e loro uso farmaceutico - Google Patents

Diamidi aromatiche acide ad attivita' antigastrinica, procedimento perla loro preparazione e loro uso farmaceutico

Info

Publication number
ITTO950554A0
ITTO950554A0 ITTO950554A ITTO950554A ITTO950554A0 IT TO950554 A0 ITTO950554 A0 IT TO950554A0 IT TO950554 A ITTO950554 A IT TO950554A IT TO950554 A ITTO950554 A IT TO950554A IT TO950554 A0 ITTO950554 A0 IT TO950554A0
Authority
IT
Italy
Prior art keywords
antigastrinic
activity
procedure
preparation
pharmaceutical use
Prior art date
Application number
ITTO950554A
Other languages
English (en)
Inventor
Francesco Makovec
Walter Peris
Lucio Rovati
Luigi Rovati
Original Assignee
Rotta Research Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rotta Research Lab filed Critical Rotta Research Lab
Publication of ITTO950554A0 publication Critical patent/ITTO950554A0/it
Priority to IT95TO000554A priority Critical patent/IT1276462B1/it
Priority to AU64182/96A priority patent/AU702749B2/en
Priority to DE69614553T priority patent/DE69614553T2/de
Priority to AT96923967T priority patent/ATE204257T1/de
Priority to US08/981,804 priority patent/US5922875A/en
Priority to JP50479697A priority patent/JP4021481B2/ja
Priority to EP96923967A priority patent/EP0839137B1/en
Priority to ES96923967T priority patent/ES2162086T3/es
Priority to PT96923967T priority patent/PT839137E/pt
Priority to DK96923967T priority patent/DK0839137T3/da
Priority to CA002224369A priority patent/CA2224369C/en
Priority to PCT/EP1996/002829 priority patent/WO1997002248A1/en
Publication of ITTO950554A1 publication Critical patent/ITTO950554A1/it
Application granted granted Critical
Publication of IT1276462B1 publication Critical patent/IT1276462B1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/20—Spiro-condensed ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyridine Compounds (AREA)
  • Medicinal Preparation (AREA)
IT95TO000554A 1995-07-03 1995-07-03 Diamidi aromatiche acide ad attivita' antigastrinica, procedimento per la loro preparazione e loro uso farmaceutico IT1276462B1 (it)

Priority Applications (12)

Application Number Priority Date Filing Date Title
IT95TO000554A IT1276462B1 (it) 1995-07-03 1995-07-03 Diamidi aromatiche acide ad attivita' antigastrinica, procedimento per la loro preparazione e loro uso farmaceutico
EP96923967A EP0839137B1 (en) 1995-07-03 1996-06-28 Aromatic acid diamides with antigastrin activity, a method for their preparation and their pharmaceutical use
PT96923967T PT839137E (pt) 1995-07-03 1996-06-28 Diamidas acidas aromaticas com accao antigastrina um metodo para a sua preparacao e para o seu uso farmaceutico
AT96923967T ATE204257T1 (de) 1995-07-03 1996-06-28 Aromatische carbonsaürediamide mit antigastrin wirkung, ihre herstellung und pharmazeutische verwendung
US08/981,804 US5922875A (en) 1995-07-03 1996-06-28 Aromatic acid diamides with antigastrin activity, a method for their preparation and their pharmaceutical use
JP50479697A JP4021481B2 (ja) 1995-07-03 1996-06-28 抗ガストリン活性を持つ芳香族酸ジアミド類、その製造法および医薬用途
AU64182/96A AU702749B2 (en) 1995-07-03 1996-06-28 Aromatic acid diamides with antigastrin activity, a method for their preparation and their pharmaceutical use
ES96923967T ES2162086T3 (es) 1995-07-03 1996-06-28 Diamidas acidas aromaticas con actividad antigastrina, un metodo para su preparacion y su uso farmaceutico.
DE69614553T DE69614553T2 (de) 1995-07-03 1996-06-28 Aromatische carbonsaürediamide mit antigastrin wirkung, ihre herstellung und pharmazeutische verwendung
DK96923967T DK0839137T3 (da) 1995-07-03 1996-06-28 Aromatiske carboxylsyrediamider med antigastrinvirkning, fremgangsmåde til deres fremstilling samt deres anvendelse som lægemidler
CA002224369A CA2224369C (en) 1995-07-03 1996-06-28 Aromatic acid diamides with antigastrin activity, a method for their preparation and their pharmaceutical use
PCT/EP1996/002829 WO1997002248A1 (en) 1995-07-03 1996-06-28 Aromatic acid diamides with antigastrin activity, a method for their preparation and their pharmaceutical use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT95TO000554A IT1276462B1 (it) 1995-07-03 1995-07-03 Diamidi aromatiche acide ad attivita' antigastrinica, procedimento per la loro preparazione e loro uso farmaceutico

Publications (3)

Publication Number Publication Date
ITTO950554A0 true ITTO950554A0 (it) 1995-07-03
ITTO950554A1 ITTO950554A1 (it) 1997-01-03
IT1276462B1 IT1276462B1 (it) 1997-10-31

Family

ID=11413693

Family Applications (1)

Application Number Title Priority Date Filing Date
IT95TO000554A IT1276462B1 (it) 1995-07-03 1995-07-03 Diamidi aromatiche acide ad attivita' antigastrinica, procedimento per la loro preparazione e loro uso farmaceutico

Country Status (12)

Country Link
US (1) US5922875A (it)
EP (1) EP0839137B1 (it)
JP (1) JP4021481B2 (it)
AT (1) ATE204257T1 (it)
AU (1) AU702749B2 (it)
CA (1) CA2224369C (it)
DE (1) DE69614553T2 (it)
DK (1) DK0839137T3 (it)
ES (1) ES2162086T3 (it)
IT (1) IT1276462B1 (it)
PT (1) PT839137E (it)
WO (1) WO1997002248A1 (it)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1286141B1 (it) * 1996-07-02 1998-07-07 Rotta Research Lab Derivati diammidici dell'acido antranilico ad attivita' antigastrinica procedimento per la loro preparazione e loro uso farmaceutico.
DE19935219A1 (de) 1999-07-27 2001-02-01 Boehringer Ingelheim Pharma Carbonsäureamide, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Herstellung
US8598164B2 (en) 2010-05-06 2013-12-03 Vertex Pharmaceuticals Incorporated Heterocyclic chromene-spirocyclic piperidine amides as modulators of ion channels
HUE028789T2 (en) 2011-02-02 2017-01-30 Vertex Pharma Pyrrolopyrazine spirocyclic piperidinamides as modulators of ion channels
CN103443105A (zh) 2011-02-18 2013-12-11 沃泰克斯药物股份有限公司 作为离子通道调节剂的苯并二氢吡喃-螺环哌啶酰胺
CN103517910B (zh) 2011-03-14 2016-12-14 沃泰克斯药物股份有限公司 作为离子通道调节剂的吗啉-螺环哌啶酰胺
UA111854C2 (uk) * 2011-09-07 2016-06-24 Інсайт Холдінгс Корпорейшн Способи і проміжні сполуки для отримання інгібіторів jak

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1241029B (it) * 1990-12-11 1993-12-27 Rotta Research Lab Derivati amidici biciclici e policiclici degli acidi glutammico, aspartico e 2-ammino adipico ad attivita' antigastrinica e procedimento per la loro preparazione
IT1263116B (it) * 1992-04-09 1996-07-30 Rotta Research Lab Derivati basici dell'acido glutammico ed acido aspartico, procedimento per la loro preparazione e loro uso farmaceutico
IT1264765B1 (it) * 1993-03-10 1996-10-04 Rotta Research Lab Derivati dell'acido glutammico ed acido aspartico, procedimento per la loro preparazione e loro uso come farmaci potenzianti la
IT1261255B (it) * 1993-09-09 1996-05-09 Rotta Research Lab Derivati acidi poliamidici ad attivita' antigastrinica, procedimento per la loro preparazione e loro uso farmaceutico.

Also Published As

Publication number Publication date
CA2224369C (en) 2008-11-25
JP4021481B2 (ja) 2007-12-12
DE69614553D1 (de) 2001-09-20
AU6418296A (en) 1997-02-05
IT1276462B1 (it) 1997-10-31
JPH11508892A (ja) 1999-08-03
DK0839137T3 (da) 2001-10-08
DE69614553T2 (de) 2002-04-18
ITTO950554A1 (it) 1997-01-03
EP0839137B1 (en) 2001-08-16
US5922875A (en) 1999-07-13
ATE204257T1 (de) 2001-09-15
ES2162086T3 (es) 2001-12-16
WO1997002248A1 (en) 1997-01-23
EP0839137A1 (en) 1998-05-06
PT839137E (pt) 2001-11-30
AU702749B2 (en) 1999-03-04
CA2224369A1 (en) 1997-01-23

Similar Documents

Publication Publication Date Title
NO306253B1 (no) Arylsulfonyl-hydroksamsyre-derivater, anvendelse derav og farmasöytisk preparat
ITMI950529A0 (it) Composizioni farmaceutiche e procedimento per la loro preparazione
FI971529L (fi) Uudet karboksyylihappojohdannaiset, niiden valmistus ja käyttö
IT8847956A0 (it) Benzo-b-pirani e piranopiridone, loro preparazione e loro impiego come medicamenti
IT1271462B (it) Antagonisti delle tachichinine,procedimento per la loro preparazione e loro impiego in formulazioni farmaceutiche.
EE04021B1 (et) 7a-( -aminoalküül)östratrieenid, nende valmistamise meetod, 7a-( -aminoalküül)östratrieene sisaldavad farmatseutilised preparaadid ja nende kasutamine ravimite valmistamiseks
ITRM920412A1 (it) Eteroprostanoidi, procedimento per la loro preparazione e loro impiego terapeutico.
ITMI913171A0 (it) Soluzione di farmaci con stabilita' aumentata a senza effetto dannoso sui tessuti e procedimento per la loro preparazione
FI950458L (fi) N-(3-aminopropyyli)-N-fenyyli-5,6,7,8-tetrahydronaftalen-2-karboksamidijohdannaiset, niiden valmistus ja terapeuttinen käyttö
BR9507771A (pt) Processos para preparação de ácido 1-Butil-2-(2'-(2H-Tetratozol-5-IL)-Bifenil-4-Ilmetil(-1H-Indol-3-Carboxílico
IT8948430A0 (it) Composti tripeptidici e loro uso farmaceutico come immuno-modulatori
EP0647229A1 (en) DIAMINE SALTS OF CLAVULIC ACID.
ITTO950554A0 (it) Diamidi aromatiche acide ad attivita' antigastrinica, procedimento perla loro preparazione e loro uso farmaceutico
ITMI922779A0 (it) Antagonisti delle tachichinine, procedimento per la loro preparazione e loro impiego in formulazioni farmaceutiche
FI925850A7 (fi) Pyridyylitiatsolidinikarboksyylihapon amidijohdannaiset, niiden valmistus ja niiden terapeuttiset käytöt
ITTO930661A0 (it) Derivati acidi poliamidici ad attivita' antigastrinica, procedimento per la loro preparazione e loro uso farmaceutico.
ITMI951417A0 (it) Composizioni farmaceutiche e procedimento per la loro preparazione
FI935888L (fi) 2-amino-6,7-dihydroksi-4-tiaheptaanihappojohdannaiset, niiden valmistus ja käyttö
FI943875L (fi) 2,3,4,5-Tetrahydro-1H-3-bentsatsepiinejä ja niiden farmaseuttisesti hyväksyttäviä happoadditiosuoloja
IT8622780A0 (it) "2-cloro-12-(-3-dimetilammino-2-metilpropil)-12h-dibenzo-/d,g//1,3,6/d iossazocine otticamente attive eprocedimento per la loro preparazione.
FR2756564B1 (fr) Derives d'acide quinoleine-8-carboxylique, leur preparation et leur application en therapeutique
FR2751970B1 (fr) Derives d'acide 6,7,8,9-tetrahydro-5h-imidazo[1,2-a]azepine- 3-acetique, leur preparation et leur application en therapeutique
IT8648189A0 (it) Benzammidi, loro procedimentodi preparazione e loro applicazione in campo terapeutico
IT1243702B (it) Composti ad attivita' nootropa, procedimento per la loro preparazione e relative composizioni farmaceutiche
FI935915A7 (fi) 2-tienyyli-imidatso(2,1-b)bentsotiatsol-3-etikkahappojohdannaiset, niiden valmistus ja terapeuttinen käyttö

Legal Events

Date Code Title Description
0001 Granted