IT1286141B1 - Derivati diammidici dell'acido antranilico ad attivita' antigastrinica procedimento per la loro preparazione e loro uso farmaceutico. - Google Patents

Derivati diammidici dell'acido antranilico ad attivita' antigastrinica procedimento per la loro preparazione e loro uso farmaceutico.

Info

Publication number
IT1286141B1
IT1286141B1 IT96TO000564A ITTO960564A IT1286141B1 IT 1286141 B1 IT1286141 B1 IT 1286141B1 IT 96TO000564 A IT96TO000564 A IT 96TO000564A IT TO960564 A ITTO960564 A IT TO960564A IT 1286141 B1 IT1286141 B1 IT 1286141B1
Authority
IT
Italy
Prior art keywords
pct
gastrinic
diamid
derivatives
preparation
Prior art date
Application number
IT96TO000564A
Other languages
English (en)
Inventor
Francesco Makovec
Walter Peris
Lucio Rovati
Luigi Rovati
Original Assignee
Rotta Research Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rotta Research Lab filed Critical Rotta Research Lab
Publication of ITTO960564A0 publication Critical patent/ITTO960564A0/it
Priority to IT96TO000564A priority Critical patent/IT1286141B1/it
Priority to CA002259345A priority patent/CA2259345C/en
Priority to AU33448/97A priority patent/AU724814B2/en
Priority to ES97929297T priority patent/ES2299184T3/es
Priority to DE69738349T priority patent/DE69738349T2/de
Priority to AT97929297T priority patent/ATE380178T1/de
Priority to JP10503828A priority patent/JP2000515497A/ja
Priority to PT97929297T priority patent/PT918754E/pt
Priority to PCT/EP1997/003361 priority patent/WO1998000404A1/en
Priority to EP97929297A priority patent/EP0918754B1/en
Priority to DK97929297T priority patent/DK0918754T3/da
Priority to US09/214,229 priority patent/US6075033A/en
Priority to ZA9705898A priority patent/ZA975898B/xx
Publication of ITTO960564A1 publication Critical patent/ITTO960564A1/it
Application granted granted Critical
Publication of IT1286141B1 publication Critical patent/IT1286141B1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/20—Spiro-condensed ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT96TO000564A 1996-07-02 1996-07-02 Derivati diammidici dell'acido antranilico ad attivita' antigastrinica procedimento per la loro preparazione e loro uso farmaceutico. IT1286141B1 (it)

Priority Applications (13)

Application Number Priority Date Filing Date Title
IT96TO000564A IT1286141B1 (it) 1996-07-02 1996-07-02 Derivati diammidici dell'acido antranilico ad attivita' antigastrinica procedimento per la loro preparazione e loro uso farmaceutico.
JP10503828A JP2000515497A (ja) 1996-07-02 1997-06-26 アントラニル酸ジアミド誘導体、その製造および抗ガストリン剤としての医薬用途
PCT/EP1997/003361 WO1998000404A1 (en) 1996-07-02 1997-06-26 Anthranilic acid diamides derivatives, their preparation and pharmaceutical use as anti-gastrin agents
ES97929297T ES2299184T3 (es) 1996-07-02 1997-06-26 Derivados de diamidas de acido antranilico, su preparacion y uso farmaceutico como agentes anti-gastrina.
DE69738349T DE69738349T2 (de) 1996-07-02 1997-06-26 Anthranilsäurediamid-derivate, ihre herstellung und pharmazeutische verwendung als antigastrinmittel
AT97929297T ATE380178T1 (de) 1996-07-02 1997-06-26 Anthranilsäure diamide derivate, ihre herstellung und pharmazeutische verwendung als antigastrin mittel
CA002259345A CA2259345C (en) 1996-07-02 1997-06-26 Anthranilic acid diamides derivatives, their preparation and pharmaceutical use as anti-gastrin agents
PT97929297T PT918754E (pt) 1996-07-02 1997-06-26 Derivados de diamidas de ácido antranílico, sua preparação e utilização farmacêutica como agentes anti-gastrina
AU33448/97A AU724814B2 (en) 1996-07-02 1997-06-26 Anthranilic acid diamides derivatives, their preparation and pharmaceutical use as anti-gastrin agents
EP97929297A EP0918754B1 (en) 1996-07-02 1997-06-26 Anthranilic acid diamides derivatives, their preparation and pharmaceutical use as anti-gastrin agents
DK97929297T DK0918754T3 (da) 1996-07-02 1997-06-26 Anthranilsyrediamidderivater, fremstilling og farmaceutisk anvendelse deraf som antigastrinmidler
US09/214,229 US6075033A (en) 1996-07-02 1997-07-02 Anthranilic acid diamides derivatives, their preparation and pharmaceutical use as anti-gastrin agents
ZA9705898A ZA975898B (en) 1996-07-02 1997-07-02 Diamide derivatives of anthranilic acid with anti-gastrin activity, a method for their preparation and their pharmaceutical use.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT96TO000564A IT1286141B1 (it) 1996-07-02 1996-07-02 Derivati diammidici dell'acido antranilico ad attivita' antigastrinica procedimento per la loro preparazione e loro uso farmaceutico.

Publications (3)

Publication Number Publication Date
ITTO960564A0 ITTO960564A0 (it) 1996-07-02
ITTO960564A1 ITTO960564A1 (it) 1998-01-02
IT1286141B1 true IT1286141B1 (it) 1998-07-07

Family

ID=11414751

Family Applications (1)

Application Number Title Priority Date Filing Date
IT96TO000564A IT1286141B1 (it) 1996-07-02 1996-07-02 Derivati diammidici dell'acido antranilico ad attivita' antigastrinica procedimento per la loro preparazione e loro uso farmaceutico.

Country Status (13)

Country Link
US (1) US6075033A (it)
EP (1) EP0918754B1 (it)
JP (1) JP2000515497A (it)
AT (1) ATE380178T1 (it)
AU (1) AU724814B2 (it)
CA (1) CA2259345C (it)
DE (1) DE69738349T2 (it)
DK (1) DK0918754T3 (it)
ES (1) ES2299184T3 (it)
IT (1) IT1286141B1 (it)
PT (1) PT918754E (it)
WO (1) WO1998000404A1 (it)
ZA (1) ZA975898B (it)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19935219A1 (de) 1999-07-27 2001-02-01 Boehringer Ingelheim Pharma Carbonsäureamide, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Herstellung
WO2002092096A1 (fr) * 2001-05-11 2002-11-21 Yamanouchi Pharmaceutical Co., Ltd. Agents antitumoraux
ES2423412T3 (es) * 2005-06-06 2013-09-20 The Board Of Trustees Of The University Of Illinois Composiciones y métodos para tratar los trastornos del sueño
EP2275421A1 (en) 2009-07-15 2011-01-19 Rottapharm S.p.A. Spiro amino compounds suitable for the treatment of inter alia sleep disorders and drug addiction

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1241029B (it) * 1990-12-11 1993-12-27 Rotta Research Lab Derivati amidici biciclici e policiclici degli acidi glutammico, aspartico e 2-ammino adipico ad attivita' antigastrinica e procedimento per la loro preparazione
IT1263116B (it) * 1992-04-09 1996-07-30 Rotta Research Lab Derivati basici dell'acido glutammico ed acido aspartico, procedimento per la loro preparazione e loro uso farmaceutico
IT1264765B1 (it) * 1993-03-10 1996-10-04 Rotta Research Lab Derivati dell'acido glutammico ed acido aspartico, procedimento per la loro preparazione e loro uso come farmaci potenzianti la
IT1261255B (it) * 1993-09-09 1996-05-09 Rotta Research Lab Derivati acidi poliamidici ad attivita' antigastrinica, procedimento per la loro preparazione e loro uso farmaceutico.
IT1276462B1 (it) * 1995-07-03 1997-10-31 Rotta Research Lab Diamidi aromatiche acide ad attivita' antigastrinica, procedimento per la loro preparazione e loro uso farmaceutico

Also Published As

Publication number Publication date
WO1998000404A1 (en) 1998-01-08
ATE380178T1 (de) 2007-12-15
DE69738349D1 (de) 2008-01-17
ITTO960564A1 (it) 1998-01-02
PT918754E (pt) 2008-03-04
ZA975898B (en) 1998-01-30
JP2000515497A (ja) 2000-11-21
DK0918754T3 (da) 2008-03-31
EP0918754B1 (en) 2007-12-05
CA2259345C (en) 2006-01-31
EP0918754A1 (en) 1999-06-02
CA2259345A1 (en) 1998-01-08
ES2299184T3 (es) 2008-05-16
DE69738349T2 (de) 2008-11-13
AU3344897A (en) 1998-01-21
AU724814B2 (en) 2000-09-28
US6075033A (en) 2000-06-13
ITTO960564A0 (it) 1996-07-02

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Legal Events

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